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The red pulp removes old red cells or malformed erythrocytes found in spherocytosis. The high blood flow is also necessary to filter bacteria like pneumococci from the blood. Without a spleen or after splenectomy, there is the risk of a fatal postsplenectomy sepsis. Therefore, these patients have to be vaccinated. Splenic particles can regenerate. The\u00a0spleen is very important in lymphocyte recirculation and lymphocyte production. 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