{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T18:26:23Z","timestamp":1778783183006,"version":"3.51.4"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2021,3,9]],"date-time":"2021-03-09T00:00:00Z","timestamp":1615248000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,3,9]],"date-time":"2021-03-09T00:00:00Z","timestamp":1615248000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bioprocess Biosyst Eng"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1007\/s00449-021-02547-1","type":"journal-article","created":{"date-parts":[[2021,3,9]],"date-time":"2021-03-09T15:03:34Z","timestamp":1615302214000},"page":"1649-1658","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Oxytetracycline and paracetamol biodegradation performance in the same enriched feed medium with aerobic nitrification\/anaerobic denitrification SBR"],"prefix":"10.1007","volume":"44","author":[{"given":"Aytekin","family":"Celik","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,3,9]]},"reference":[{"key":"2547_CR1","doi-asserted-by":"publisher","first-page":"1176","DOI":"10.1111\/raq.12286","volume":"11","author":"JF Leal","year":"2019","unstructured":"Leal JF, Santos EBH, Esteves I (2019) Oxytetracycline in intensive aquaculture: water quality during and after its administration, environmental fate, toxicity and bacterial resistance. Rev Aquacult 11:1176\u20131194. https:\/\/doi.org\/10.1111\/raq.12286","journal-title":"Rev Aquacult"},{"key":"2547_CR2","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.biortech.2012.11.022","volume":"129","author":"GF Yan","year":"2013","unstructured":"Yan GF, Zhang QQ, Jin RC (2013) Changes in the nitrogen removal performance and the properties of granullar sludge in an ananammox system under oxytetracycline (otc) stress. Bioresour Technol 129:65\u201371","journal-title":"Bioresour Technol"},{"key":"2547_CR3","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1016\/j.jhazmat.2015.11.043","volume":"305","author":"Y Liu","year":"2016","unstructured":"Liu Y, He X, Fu Y, Dionysiou DD (2016) Kinetics and mechanism investigation on the destruction of oxytetracycline by UV-254nm activation of persulfate. J Hazard Mater 305:229\u2013239","journal-title":"J Hazard Mater"},{"key":"2547_CR4","first-page":"131","volume-title":"Oxytetracycline","author":"FAO","year":"1990","unstructured":"FAO (1990) Oxytetracycline. Residues of some veterinary drugs in animals and foods Food and Agriculture Organization of the United Nations, Rome, p 131"},{"issue":"14","key":"2547_CR5","doi-asserted-by":"publisher","first-page":"3933","DOI":"10.1021\/es0353053","volume":"38","author":"AL Boreen","year":"2004","unstructured":"Boreen AL, Arnold WA, McNeill K (2004) Photochemical fate of sulfa drugs in the aquatic environment: sulfa drugs containing five-membered heterocyclic groups. Environ Sci Technol 38(14):3933\u20133940","journal-title":"Environ Sci Technol"},{"key":"2547_CR6","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.apcatb.2013.01.003","volume":"134","author":"C Zhao","year":"2013","unstructured":"Zhao C, Pelaez M, Duan XD, Deng H, O\u2019Shea K, Fatta-Kassinos D (2013) Role of pH on photolytic and photocatalytic degradation of antibiotic oxytetracycline in aqueous solution under visible\/solar light: kinetics and mechanism studies. Appl Catal B 134:83","journal-title":"Appl Catal B"},{"key":"2547_CR7","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1016\/j.envpol.2016.03.040","volume":"213","author":"JF Leal","year":"2016","unstructured":"Leal JF, Esteves VI, Santos EBH (2016) Use of sunlight to degrade oxytetracycline in marine aquaculture\u2019s waters. Environ Pollut 213:932\u2013939","journal-title":"Environ Pollut"},{"issue":"2","key":"2547_CR8","doi-asserted-by":"publisher","first-page":"146","DOI":"10.3390\/ani4020146","volume":"4","author":"DI Masse","year":"2014","unstructured":"Masse DI, Saady NMC, Gilbert Y (2014) Potantial of biological process to eliminate antibiotics in livestock manure on overview. Animals 4(2):146\u2013163","journal-title":"Animals"},{"key":"2547_CR9","doi-asserted-by":"publisher","first-page":"5895","DOI":"10.1007\/s00216-016-9704-8","volume":"408","author":"SF Mbokou","year":"2016","unstructured":"Mbokou SF, Ponti\u00e9 M, Razafimandimby B, Bouchara JP, Njanja E, Tonle KI (2016) Evaluation of the degradation of acetaminophen by the filamentous fungus Scedosporium dehoogii using carbon-based modified electrodes. Anal Bioanal Chem 408:5895","journal-title":"Anal Bioanal Chem"},{"issue":"22","key":"2547_CR10","doi-asserted-by":"publisher","first-page":"21498","DOI":"10.1007\/s11356-018-2517-x","volume":"25","author":"J \u017bur","year":"2018","unstructured":"\u017bur J, Pi\u0144ski A, Marchlewicz A, Hupert-Kocurek K, Wojcieszy\u0144ska D, Guzik U (2018) Organic micropollutants paracetamol and ibuprofen\u2014toxicity, biodegradation, and genetic background of their utilization by bacteria. Environ Sci Pollut Res Int 25(22):21498\u201321524","journal-title":"Environ Sci Pollut Res Int"},{"key":"2547_CR11","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1016\/j.ecoleng.2016.08.010","volume":"98","author":"J Vymazal","year":"2017","unstructured":"Vymazal J, B\u0159ezinov\u00e1 TD, Ko\u017eeluh M, Kule L (2017) Occurrence and removal of pharmaceuticals in four full-scale constructed wetlands in the Czech Republic \u2013 the first year of monitoring. Ecol Eng 98:354\u2013364","journal-title":"Ecol Eng"},{"key":"2547_CR12","doi-asserted-by":"publisher","first-page":"2507","DOI":"10.1016\/j.chemosphere.2015.10.100","volume":"144","author":"AMPT Pereira","year":"2016","unstructured":"Pereira AMPT, Silva LJG, Linoa CM, Meisel LM, Pena A (2016) Assessing environmental risk of pharmaceuticals in Portugal: an approach for the selection of the Portuguese monitoring stations in line with Directive 2013\/39\/EU. Chemosphere 144:2507\u20132515","journal-title":"Chemosphere"},{"issue":"1","key":"2547_CR13","doi-asserted-by":"publisher","first-page":"954","DOI":"10.1016\/j.envpol.2017.08.032","volume":"231","author":"J Wilkinson","year":"2017","unstructured":"Wilkinson J, Hooda PS, Barker J, Barton S, Swinden J (2017) Occurrence, fate and transformation of emerging contaminants in water: an overarching review of the field. Environ Pollut 231(1):954\u2013970","journal-title":"Environ Pollut"},{"key":"2547_CR14","doi-asserted-by":"publisher","first-page":"976","DOI":"10.1016\/j.envpol.2017.07.082","volume":"229","author":"M Brumovsk\u00fd","year":"2017","unstructured":"Brumovsk\u00fd M, Be\u010danov\u00e1 J, Kohoutek J, Borghini M, Nizzetto L (2017) Contaminants of emerging concern in the open sea waters of the Western Mediterranean. Environ Pollut 229:976\u2013983","journal-title":"Environ Pollut"},{"key":"2547_CR15","first-page":"110","volume-title":"The life-cycle of pharmaceuticals in the environment","author":"BM Peake","year":"2015","unstructured":"Peake BM, Braund R, Tong A, Louis A (2015) The life-cycle of pharmaceuticals in the environment. Woodhead Publishing Series, Cambridge, p 110"},{"key":"2547_CR16","doi-asserted-by":"publisher","first-page":"7358","DOI":"10.1016\/j.jece.2018.08.036","volume":"6","author":"S Periyasamya","year":"2018","unstructured":"Periyasamya S, Muthuchamya M (2018) Electrochemical oxidation of paracetamol in water by graphite anode: Effect of pH, electrolyte concentration and current density. J Environ Chem Eng 6:7358\u20137367","journal-title":"J Environ Chem Eng"},{"issue":"10","key":"2547_CR17","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1016\/S0165-9936(03)01105-1","volume":"22","author":"M Petrovi\u0107","year":"2003","unstructured":"Petrovi\u0107 M, Gonz\u00e1lez S, Barcel\u00f3 D (2003) Analysis and removal of emerging contaminants in wastewater and drinking water. Trends Analyt Chem 22(10):685\u2013696","journal-title":"Trends Analyt Chem"},{"issue":"1904","key":"2547_CR18","first-page":"3979","volume":"367","author":"M Petrovic","year":"2009","unstructured":"Petrovic M, L\u00f3pez de Alda MJ, D\u00edaz-Cruz S, Postigo C, Radjenovic J, Gros M, Barcel\u00f3 D (2009) Fate and removal of pharmaceuticals and illicit drugs in conventional and membrane bioreactor wastewater treatment plants and by riverbank filtration. Philos Trans Math Phys Eng Sci 367(1904):3979\u20134003","journal-title":"Philos Trans Math Phys Eng Sci"},{"key":"2547_CR19","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1016\/S0731-7085(02)00211-X","volume":"29","author":"G Chen","year":"2002","unstructured":"Chen G, Ye J, Bao H, Yang P (2002) Determination of the rate constants and activation energy of acetaminophen hydrolysis by capillary electrophoresis. J Pharm Biomed Anal 29:843\u2013850","journal-title":"J Pharm Biomed Anal"},{"key":"2547_CR20","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1080\/00032719108052889","volume":"24","author":"A Yesilada","year":"1991","unstructured":"Yesilada A, Erdogan H, Ertan M (1991) Second derivative spectrophotometric determination of p-Aminophenol in the presence of paracetamol. Anal Lett 24:129\u2013138","journal-title":"Anal Lett"},{"issue":"1","key":"2547_CR21","first-page":"7","volume":"9","author":"A Uygur","year":"2004","unstructured":"Uygur A, Karg\u0131 F, Baskaya HS (2004) Effects of sludge age on nutrient removal performance in a sequencing batch reactor. J Uluda\u011f Univ Faculty Eng Arch 9(1):7","journal-title":"J Uluda\u011f Univ Faculty Eng Arch"},{"key":"2547_CR22","doi-asserted-by":"publisher","first-page":"998","DOI":"10.1016\/j.chemosphere.2017.11.136","volume":"193","author":"L Hang","year":"2018","unstructured":"Hang L, Yongkui Y, Huifang S, Lin Z, Yu L (2018) Fate of tetracycline in enhanced biological nutrient removal process. Chemosphere 193:998\u20131003","journal-title":"Chemosphere"},{"key":"2547_CR23","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/j.jes.2017.10.006","volume":"69","author":"Y Wu","year":"2018","unstructured":"Wu Y, Yue Q, Gao Y, Ren Z, Gao B (2018) Performance of bimetallic nanoscale zero-valent iron particles for removal of oxytetracycline. J Environ Sci 69:173\u2013182","journal-title":"J Environ Sci"},{"issue":"15","key":"2547_CR24","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.jenvman.2018.08.022","volume":"226","author":"S Tang","year":"2018","unstructured":"Tang S, Yuan D, Rao Y, Zhang J, Qu Y, Gu J (2018) Evaluation of antibiotic oxytetracycline removal in water using a gas phase dielectric barrier discharge plasma. J Environ Manage 226(15):22\u201329","journal-title":"J Environ Manage"},{"issue":"15","key":"2547_CR25","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/j.matlet.2018.01.081","volume":"217","author":"J Li","year":"2018","unstructured":"Li J, Tian JJ, Wang LG, Chang CT (2018) Photocatalytic hydrogen production and photodegradation of oxytetracycline by Cu-CdS composites. Mater Lett 217(15):243\u2013246","journal-title":"Mater Lett"},{"key":"2547_CR26","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1016\/j.biortech.2018.07.133","volume":"267","author":"D Cheng","year":"2018","unstructured":"Cheng D, Ngo HH, Guo W, Liu Y, Chang SW, Nguyen DD, Nghiem LD, Zhou L, Ni B (2018) Anaerobic membrane bioreactors for antibiotic wastewater treatment: Performance and membrane fouling issues. Biores Technol 267:714\u2013724","journal-title":"Biores Technol"},{"issue":"15","key":"2547_CR27","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1016\/j.memsci.2018.03.005","volume":"554","author":"XQ Cheng","year":"2018","unstructured":"Cheng XQ, Wang ZX, Zhang Y, Ma J, Shao L (2018) Bio-inspired loose nanofiltration membranes with optimized separation performance for antibiotics removals. J Membr Sci 554(15):385\u2013394","journal-title":"J Membr Sci"},{"key":"2547_CR28","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.jhazmat.2018.05.040","volume":"356","author":"A Celik","year":"2018","unstructured":"Celik A, Casey E, Hasar H (2018) Degradation of oxytetracycline under autotrophic nitrifying conditions in a membrane aerated biofilm reactor and community fingerprinting. J Hazard Mater 356:26\u201333","journal-title":"J Hazard Mater"},{"key":"2547_CR29","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1016\/j.watres.2019.06.014","volume":"161","author":"X Wang","year":"2019","unstructured":"Wang X, Shen J, Kang J, Zhao X, Chen Z (2019) Mechanism of oxytetracycline removal by aerobic granular sludge in SBR. Water Res 161:308\u2013318","journal-title":"Water Res"},{"key":"2547_CR30","doi-asserted-by":"publisher","first-page":"103282","DOI":"10.1016\/j.jece.2019.103282","volume":"7","author":"D Dionisi","year":"2019","unstructured":"Dionisi D, Etteh CC (2019) Effectofprocessconditionsontheaerobicbiodegradationofphenoland paracetamol by open mixed microbial cultures. J Environ Chem Eng 7:103282","journal-title":"J Environ Chem Eng"},{"key":"2547_CR31","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1016\/j.chemosphere.2018.04.179","volume":"206","author":"J \u017bur","year":"2018","unstructured":"\u017bur J, Wojcieszy\u0144ska D, Hupert-Kocurek K, Marchlewicz A, Guzik U (2018) Paracetamol\u2013toxicity and microbial utilization. Pseudomonas moorei KB4 as a case study for exploring degradation pathway. Chemosphere 206:192\u2013202","journal-title":"Chemosphere"}],"container-title":["Bioprocess and Biosystems Engineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00449-021-02547-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00449-021-02547-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00449-021-02547-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T03:48:19Z","timestamp":1624938499000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00449-021-02547-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,9]]},"references-count":31,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["2547"],"URL":"https:\/\/doi.org\/10.1007\/s00449-021-02547-1","relation":{},"ISSN":["1615-7591","1615-7605"],"issn-type":[{"value":"1615-7591","type":"print"},{"value":"1615-7605","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,9]]},"assertion":[{"value":"2 October 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 March 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 March 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"There is nothing to be a conflict of interest in this study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}