{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T14:04:03Z","timestamp":1788357843659,"version":"build-2803163510"},"reference-count":68,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T00:00:00Z","timestamp":1738713600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T00:00:00Z","timestamp":1738713600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Ataturk University"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bioprocess Biosyst Eng"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:p>This study assesses the antimicrobial, antibiofilm, and antiurease properties of selenium (Se), zinc (Zn), and zinc selenide (ZnSe) nanoparticles (NPs) against clinically pathogenic strains of <jats:italic>Streptococcus salivarius<\/jats:italic> and <jats:italic>Proteus mirabilis<\/jats:italic>. The Se, Zn, and ZnSe NPs, synthesized by <jats:italic>Pseudomonas aeruginosa<\/jats:italic> OG1, were characterized using transmission electron microscopy (TEM) revealing average sizes of approximately 30\u2009\u00b1\u200910\u00a0nm, 30\u2009\u00b1\u200915\u00a0nm, and 40\u2009\u00b1\u200910 nm, respectively. Atomic force microscopy (AFM) was used to examine the morphological and topological characteristics of the NPs. The structural and crystal characteristics were investigated using X-ray diffraction (XRD). Among the evaluated NPs, Zn NPs at a concentration of 200\u00a0mg\/mL exhibited the most substantial growth inhibition zone against <jats:italic>S. salivarius<\/jats:italic>. Conversely, the highest antibiofilm activity was observed against <jats:italic>P. mirabilis<\/jats:italic>, notably with 200\u00a0\u00b5g\/mL Zn NPs. In the context of antiurease activity, both 100\u00a0\u03bcg Zn and ZnSe NPs caused complete urease inhibition (100%) in <jats:italic>P. mirabilis<\/jats:italic> within the initial 5\u00a0h, with notable inhibition rates of 94% and 80%, respectively, observed against <jats:italic>S. salivarius<\/jats:italic>. Significantly, in the current landscape of NP research primarily focused on antimicrobial and antibiofilm properties, our study stands out due to its pioneering exploration of antiurease activities with these NPs. This distinctive emphasis on antiurease effects contributes original and unique value to our study, offering novel insights into the broader spectrum of NP applications, and paving the way for potential therapeutic advancements.<\/jats:p>","DOI":"10.1007\/s00449-025-03130-8","type":"journal-article","created":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T12:13:35Z","timestamp":1738757615000},"page":"589-603","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Antimicrobial, antibiofilm, and antiurease activities of green-synthesized Zn, Se, and ZnSe nanoparticles against Streptococcus salivarius and Proteus mirabilis"],"prefix":"10.1007","volume":"48","author":[{"given":"Sumeyra","family":"Gurkok","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Ozdal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuba","family":"Cakici","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esabi Basaran","family":"Kurbanoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,2,5]]},"reference":[{"key":"3130_CR1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsusc.2023.157522","volume":"631","author":"T \u00c7ak\u0131c\u0131","year":"2023","unstructured":"\u00c7ak\u0131c\u0131 T, Ajjaq A, \u00c7a\u011f\u0131rtekin AO, Barin \u00d6, \u00d6zdal M, Acar S (2023) Surface activation of Si-based Schottky diodes by bacterial biosynthesized AgInSe2 trimetallic alloy nanoparticles with evidenced negative capacitance and enhanced electro-dielectric performance. Appl Surf Sci 631:157522. https:\/\/doi.org\/10.1016\/j.apsusc.2023.157522","journal-title":"Appl Surf Sci"},{"key":"3130_CR2","doi-asserted-by":"publisher","DOI":"10.1016\/j.inoche.2022.109362","volume":"139","author":"R Krishnamoorthi","year":"2022","unstructured":"Krishnamoorthi R, Mahalingam PU, Malaikozhundan B (2022) Edible mushroom extract engineered Ag NPs as safe antimicrobial and antioxidant agents with no significant cytotoxicity on human dermal fibroblast cells. Inorg Chem Commun 139:109362. https:\/\/doi.org\/10.1016\/j.inoche.2022.109362","journal-title":"Inorg Chem Commun"},{"key":"3130_CR3","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1080\/17518253.2020.1802517","volume":"13","author":"I Ijaz","year":"2020","unstructured":"Ijaz I, Gilani E, Nazir A, Bukhari A (2020) Detail review on chemical, physical and green synthesis, classification, characterizations and applications of nanoparticles. Green Chem Lett Rev 13:223\u2013245. https:\/\/doi.org\/10.1080\/17518253.2020.1802517","journal-title":"Green Chem Lett Rev"},{"key":"3130_CR4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jksus.2023.102642","volume":"35","author":"G Chackaravarthi","year":"2023","unstructured":"Chackaravarthi G, Alharbi NS, Mythili Gnanamangai B, Ramachandran G, Kanisha Chelliah C, Rajivgandhi G, Maruthupandy M, Quero F, Natesan M, Li W-J (2023) Anti-biofilm efficacy of marine actinomycete mediated zinc oxide nanoparticles increased the intracellular damages in biofilm forming K. pneumoniae. J King Saud Univ Sci 35:102642. https:\/\/doi.org\/10.1016\/j.jksus.2023.102642","journal-title":"J King Saud Univ Sci"},{"key":"3130_CR5","doi-asserted-by":"publisher","first-page":"7278","DOI":"10.3390\/ma8115377","volume":"8","author":"M Shah","year":"2015","unstructured":"Shah M, Fawcett D, Sharma S, Tripathy S, Poinern G (2015) Green synthesis of metallic nanoparticles via biological entities. Materials 8:7278\u20137308. https:\/\/doi.org\/10.3390\/ma8115377","journal-title":"Materials"},{"key":"3130_CR6","doi-asserted-by":"publisher","DOI":"10.1016\/j.mssp.2019.104610","author":"T \u00c7ak\u0131c\u0131","year":"2019","unstructured":"\u00c7ak\u0131c\u0131 T, \u00d6zdal M, Kundakc\u0131 M, Kayal\u0131 R (2019) ZnSe and CuSe NP\u2019s by microbial green synthesis method and comparison of I-V characteristics of Au\/ZnSe\/p-Si\/Al and Au\/CuSe\/p-Si\/Al structures. Mater Sci Semicond Process. https:\/\/doi.org\/10.1016\/j.mssp.2019.104610","journal-title":"Mater Sci Semicond Process"},{"key":"3130_CR7","doi-asserted-by":"publisher","first-page":"9","DOI":"10.12693\/APhysPolA.140.9","volume":"140","author":"T \u00c7ak\u0131c\u0131","year":"2021","unstructured":"\u00c7ak\u0131c\u0131 T, G\u00fcr \u00d6zdal \u00d6 (2021) Synthesising of MgSe complex nanoparticle via bacteria and characterisation of fabricated MgSe\/p-Si structure. Acta Phys Pol A 140:9\u201313. https:\/\/doi.org\/10.12693\/APhysPolA.140.9","journal-title":"Acta Phys Pol A"},{"key":"3130_CR8","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1007\/s12668-022-00968-0","volume":"12","author":"M Kumar","year":"2022","unstructured":"Kumar M, Upadhyay LSB, Kerketta A, Vasanth D (2022) Extracellular synthesis of silver nanoparticles using a novel bacterial strain Kocuria rhizophila BR-1: process optimization and evaluation of antibacterial activity. Bionanoscience 12:423\u2013438. https:\/\/doi.org\/10.1007\/s12668-022-00968-0","journal-title":"Bionanoscience"},{"key":"3130_CR9","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1016\/j.jphotobiol.2017.08.014","volume":"174","author":"B Malaikozhundan","year":"2017","unstructured":"Malaikozhundan B, Vaseeharan B, Vijayakumar S, Thangaraj MP (2017) Bacillus thuringiensis coated zinc oxide nanoparticle and its biopesticidal effects on the pulse beetle, Callosobruchus maculatus. J Photochem Photobiol B Biol 174:306\u2013314. https:\/\/doi.org\/10.1016\/j.jphotobiol.2017.08.014","journal-title":"J Photochem Photobiol B Biol"},{"key":"3130_CR10","doi-asserted-by":"publisher","first-page":"474","DOI":"10.1016\/j.colsurfb.2014.05.027","volume":"121","author":"NI Hulkoti","year":"2014","unstructured":"Hulkoti NI, Taranath TC (2014) Biosynthesis of nanoparticles using microbes\u2014A review. Colloids Surf B Biointerfaces 121:474\u2013483. https:\/\/doi.org\/10.1016\/j.colsurfb.2014.05.027","journal-title":"Colloids Surf B Biointerfaces"},{"key":"3130_CR11","doi-asserted-by":"publisher","first-page":"2185","DOI":"10.1016\/j.sjbs.2020.04.026","volume":"27","author":"KI Alsamhary","year":"2020","unstructured":"Alsamhary KI (2020) Eco-friendly synthesis of silver nanoparticles by Bacillus subtilis and their antibacterial activity. Saudi J Biol Sci 27:2185\u20132191. https:\/\/doi.org\/10.1016\/j.sjbs.2020.04.026","journal-title":"Saudi J Biol Sci"},{"key":"3130_CR12","doi-asserted-by":"publisher","first-page":"19593","DOI":"10.1016\/j.ceramint.2020.05.020","volume":"46","author":"P Gnanamozhi","year":"2020","unstructured":"Gnanamozhi P, Rajivgandhi G, Alharbi NS, Kadaikunnan S, Khaled JM, Almanaa TN, Pandiyan V, Li W-J (2020) Enhanced antibacterial and photocatalytic degradation of reactive red 120 using lead substituted ZnO nanoparticles prepared by ultrasonic-assisted co-precipitation method. Ceram Int 46:19593\u201319599. https:\/\/doi.org\/10.1016\/j.ceramint.2020.05.020","journal-title":"Ceram Int"},{"key":"3130_CR13","doi-asserted-by":"publisher","first-page":"902","DOI":"10.3390\/catal11080902","volume":"11","author":"P Dikshit","year":"2021","unstructured":"Dikshit P, Kumar J, Das A, Sadhu S, Sharma S, Singh S, Gupta P, Kim B (2021) Green synthesis of metallic nanoparticles: applications and limitations. Catalysts 11:902. https:\/\/doi.org\/10.3390\/catal11080902","journal-title":"Catalysts"},{"key":"3130_CR14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jece.2020.104533","volume":"8","author":"M Maruthupandy","year":"2020","unstructured":"Maruthupandy M, Rajivgandhi GN, Quero F, Li WJ (2020) Anti-quorum sensing and anti-biofilm activity of nickel oxide nanoparticles against Pseudomonas aeruginosa. J Environ Chem Eng 8:104533. https:\/\/doi.org\/10.1016\/j.jece.2020.104533","journal-title":"J Environ Chem Eng"},{"key":"3130_CR15","doi-asserted-by":"publisher","DOI":"10.1016\/j.rinp.2021.104065","volume":"23","author":"GN Rajivgandhi","year":"2021","unstructured":"Rajivgandhi GN, Ramachandran G, Kanisha CC, Alharbi NS, Kadaikunnan S, Khaled JM, Alanzi KF, Li W-J (2021) Effect of Ti and Cu doping on the structural, optical, morphological and anti-bacterial properties of nickel ferrite nanoparticles. Results Phys 23:104065. https:\/\/doi.org\/10.1016\/j.rinp.2021.104065","journal-title":"Results Phys"},{"key":"3130_CR16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2022.114787","volume":"653","author":"G Rajivgandhi","year":"2022","unstructured":"Rajivgandhi G, Ramachandran G, Chackaravarthi G, Chelliah CK, Maruthupandy M, Quero F, AL-mekhlafi FA, Wadaan MA, Li W-J, (2022) Preparation of antibacterial Zn and Ni substituted cobalt ferrite nanoparticles for efficient biofilm eradication. Anal Biochem 653:114787. https:\/\/doi.org\/10.1016\/j.ab.2022.114787","journal-title":"Anal Biochem"},{"key":"3130_CR17","doi-asserted-by":"publisher","DOI":"10.1016\/j.idcr.2022.e01410","volume":"27","author":"S Okada","year":"2022","unstructured":"Okada S, Ichimura Y, Iinuma M (2022) Emphysematous cystitis due to Streptococcus salivarius infection in a patient with a neurogenic bladder. IDCases 27:e01410. https:\/\/doi.org\/10.1016\/j.idcr.2022.e01410","journal-title":"IDCases"},{"key":"3130_CR18","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1128\/iai.64.2.585-592.1996","volume":"64","author":"YY Chen","year":"1996","unstructured":"Chen YY, Clancy KA, Burne RA (1996) Streptococcus salivarius urease: genetic and biochemical characterization and expression in a dental plaque streptococcus. Infect Immun 64:585\u2013592. https:\/\/doi.org\/10.1128\/iai.64.2.585-592.1996","journal-title":"Infect Immun"},{"key":"3130_CR19","doi-asserted-by":"publisher","first-page":"e00496","DOI":"10.1128\/AEM.00496-17","volume":"83","author":"B Chakraborty","year":"2017","unstructured":"Chakraborty B, Burne RA (2017) Effects of arginine on streptococcus mutans growth, virulence gene expression, and stress tolerance. Appl Environ Microbiol 83:e00496-e517. https:\/\/doi.org\/10.1128\/AEM.00496-17","journal-title":"Appl Environ Microbiol"},{"key":"3130_CR20","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1016\/S0003-9969(02)00114-0","volume":"47","author":"L Wong","year":"2002","unstructured":"Wong L, Sissons C, Pearce EI, Cutress T (2002) Calcium phosphate deposition in human dental plaque microcosm biofilms induced by a ureolytic pH-rise procedure. Arch Oral Biol 47:779\u2013790. https:\/\/doi.org\/10.1016\/S0003-9969(02)00114-0","journal-title":"Arch Oral Biol"},{"key":"3130_CR21","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1016\/S1286-4579(00)00312-9","volume":"2","author":"RA Burne","year":"2000","unstructured":"Burne RA, Chen Y-YM (2000) Bacterial ureases in infectious diseases. Microbes Infect 2:533\u2013542. https:\/\/doi.org\/10.1016\/S1286-4579(00)00312-9","journal-title":"Microbes Infect"},{"key":"3130_CR22","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0139315","volume":"10","author":"E Morou-Bermudez","year":"2015","unstructured":"Morou-Bermudez E, Rodriguez S, Bello AS, Dominguez-Bello MG (2015) Urease and dental plaque microbial profiles in children. PLoS ONE 10:e0139315. https:\/\/doi.org\/10.1371\/journal.pone.0139315","journal-title":"PLoS ONE"},{"key":"3130_CR23","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2020.00414","author":"R Wasfi","year":"2020","unstructured":"Wasfi R, Hamed SM, Amer MA, Fahmy LI (2020) Proteus mirabilis Biofilm: Development and therapeutic strategies. Front Cell Infect Microbiol. https:\/\/doi.org\/10.3389\/fcimb.2020.00414","journal-title":"Front Cell Infect Microbiol"},{"key":"3130_CR24","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1007\/978-1-4613-4295-3_69","volume-title":"Urolithiasis Research","author":"DP Griffith","year":"1976","unstructured":"Griffith DP, Musher DM (1976) Urease: Principal cause of infection stones. Urolithiasis Research. Springer, US, Boston, MA, pp 451\u2013454"},{"key":"3130_CR25","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/j.ijbiomac.2022.08.087","volume":"220","author":"R Krishnamoorthi","year":"2022","unstructured":"Krishnamoorthi R, Srinivash M, Mahalingam PU, Malaikozhundan B, Suganya P, Gurushankar K (2022) Antimicrobial, anti-biofilm, antioxidant and cytotoxic effects of bacteriocin by Lactococcus lactis strain CH3 isolated from fermented dairy products\u2014An in vitro and in silico approach. Int J Biol Macromol 220:291\u2013306. https:\/\/doi.org\/10.1016\/j.ijbiomac.2022.08.087","journal-title":"Int J Biol Macromol"},{"key":"3130_CR26","doi-asserted-by":"publisher","first-page":"115","DOI":"10.5599\/admet.1172","volume":"10","author":"M Ozdal","year":"2022","unstructured":"Ozdal M, Gurkok S (2022) Recent advances in nanoparticles as antibacterial agent. ADMET DMPK 10:115\u2013129. https:\/\/doi.org\/10.5599\/admet.1172","journal-title":"ADMET DMPK"},{"key":"3130_CR27","doi-asserted-by":"publisher","first-page":"601","DOI":"10.3390\/md19110601","volume":"19","author":"F Khan","year":"2021","unstructured":"Khan F, Kang M-G, Jo D-M, Chandika P, Jung W-K, Kang HW, Kim Y-M (2021) Phloroglucinol-Gold and -Zinc Oxide nanoparticles: Antibiofilm and antivirulence activities towards Pseudomonas aeruginosa PAO1. Mar Drugs 19:601. https:\/\/doi.org\/10.3390\/md19110601","journal-title":"Mar Drugs"},{"key":"3130_CR28","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1007\/s42770-020-00406-x","volume":"52","author":"CD de Lacerda","year":"2021","unstructured":"de Lacerda CD, de Souza JB, Bueno EV, de Medeiros SM, FR, Cavalcanti IDL, Cavalcanti IMF, (2021) Antibacterial and antibiofilm potential of silver nanoparticles against antibiotic-sensitive and multidrug-resistant Pseudomonas aeruginosa strains. Brazilian J Microbiol 52:267\u2013278. https:\/\/doi.org\/10.1007\/s42770-020-00406-x","journal-title":"Brazilian J Microbiol"},{"key":"3130_CR29","doi-asserted-by":"publisher","first-page":"2788","DOI":"10.1007\/s12011-020-02369-4","volume":"199","author":"AA Mohamed","year":"2021","unstructured":"Mohamed AA, Abu-Elghait M, Ahmed NE, Salem SS (2021) Eco-friendly mycogenic synthesis of ZnO and CuO nanoparticles for in vitro antibacterial, antibiofilm, and antifungal applications. Biol Trace Elem Res 199:2788\u20132799. https:\/\/doi.org\/10.1007\/s12011-020-02369-4","journal-title":"Biol Trace Elem Res"},{"key":"3130_CR30","doi-asserted-by":"publisher","first-page":"893","DOI":"10.3390\/life12060893","volume":"12","author":"SS Salem","year":"2022","unstructured":"Salem SS, Badawy MSEM, Al-Askar AA, Arishi AA, Elkady FM, Hashem AH (2022) Green biosynthesis of selenium nanoparticles using orange peel waste: Characterization, antibacterial and antibiofilm activities against multidrug-resistant bacteria. Life 12:893. https:\/\/doi.org\/10.3390\/life12060893","journal-title":"Life"},{"key":"3130_CR31","doi-asserted-by":"publisher","DOI":"10.1002\/tcr.202200026","volume":"22","author":"S Loharch","year":"2022","unstructured":"Loharch S, Berlicki \u0141 (2022) Rational development of bacterial ureases inhibitors. Chem Rec 22:e202200026. https:\/\/doi.org\/10.1002\/tcr.202200026","journal-title":"Chem Rec"},{"key":"3130_CR32","doi-asserted-by":"publisher","first-page":"1146","DOI":"10.3390\/nano10061146","volume":"10","author":"MA Ali","year":"2020","unstructured":"Ali MA, Ahmed T, Wu W, Hossain A, Hafeez R, Islam Masum MM, Wang Y, An Q, Sun G, Li B (2020) Advancements in plant and microbe-based synthesis of metallic nanoparticles and their antimicrobial activity against plant pathogens. Nanomaterials 10:1146. https:\/\/doi.org\/10.3390\/nano10061146","journal-title":"Nanomaterials"},{"key":"3130_CR33","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1007\/s40097-021-00460-3","volume":"13","author":"H Ashraf","year":"2022","unstructured":"Ashraf H, Meer B, Iqbal J, Ali JS, Andleeb A, Butt H, Zia M, Mehmood A, Nadeem M, Drouet S, Blondeau J-P, Giglioli-Guivarc\u2019h N, Liu C, Hano C, Abbasi BH, (2022) Comparative evaluation of chemically and green synthesized zinc oxide nanoparticles: their in vitro antioxidant, antimicrobial, cytotoxic and anticancer potential towards HepG2 cell line. J Nanostructure Chem 13:243\u2013261. https:\/\/doi.org\/10.1007\/s40097-021-00460-3","journal-title":"J Nanostructure Chem"},{"key":"3130_CR34","doi-asserted-by":"publisher","first-page":"11783","DOI":"10.1021\/acsomega.1c01512","volume":"6","author":"A Sajjad","year":"2021","unstructured":"Sajjad A, Bhatti SH, Ali Z, Jaffari GH, Khan NA, Rizvi ZF, Zia M (2021) Photoinduced fabrication of zinc oxide nanoparticles: transformation of morphological and biological response on light irradiance. ACS Omega 6:11783\u201311793. https:\/\/doi.org\/10.1021\/acsomega.1c01512","journal-title":"ACS Omega"},{"key":"3130_CR35","doi-asserted-by":"publisher","first-page":"63","DOI":"10.5604\/17331331.1197325","volume":"65","author":"M Ozdal","year":"2016","unstructured":"Ozdal M, Ozdal OG, Algur OF (2016) Isolation and characterization of \u03b1-endosulfan degrading bacteria from the microflora of cockroaches. Polish J Microbiol 65:63\u201368. https:\/\/doi.org\/10.5604\/17331331.1197325","journal-title":"Polish J Microbiol"},{"key":"3130_CR36","doi-asserted-by":"publisher","first-page":"13886","DOI":"10.1038\/s41598-023-41103-7","volume":"13","author":"K Singh","year":"2023","unstructured":"Singh K, Nancy BM, Singh G, Mubarak NM, Singh J (2023) Light-absorption-driven photocatalysis and antimicrobial potential of PVP-capped zinc oxide nanoparticles. Sci Rep 13:13886. https:\/\/doi.org\/10.1038\/s41598-023-41103-7","journal-title":"Sci Rep"},{"key":"3130_CR37","doi-asserted-by":"publisher","first-page":"359","DOI":"10.53433\/yyufbed.1194875","volume":"28","author":"S G\u00fcrk\u00f6k","year":"2023","unstructured":"G\u00fcrk\u00f6k S, \u00d6zdal M (2023) Antimicrobial, antibiofilm and antiurease activities of microbially synthesized silver nanoparticles against Proteus mirabilis. Van Yuzuncu Y\u0131l Univ Inst Nat Appl Sci 28:359\u2013369. https:\/\/doi.org\/10.53433\/yyufbed.1194875","journal-title":"Van Yuzuncu Y\u0131l Univ Inst Nat Appl Sci"},{"key":"3130_CR38","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1007\/s12223-023-01100-9","volume":"69","author":"OG Ozdal","year":"2024","unstructured":"Ozdal OG (2024) Green synthesis of Ag, Se, and Ag2Se nanoparticles by Pseudomonas aeruginosa: characterization and their biological and photocatalytic applications. Folia Microbiol 69:625\u2013638. https:\/\/doi.org\/10.1007\/s12223-023-01100-9","journal-title":"Folia Microbiol"},{"key":"3130_CR39","first-page":"49","volume":"36","author":"AW Bauer","year":"1966","unstructured":"Bauer AW, Kirby WM, Sherris JC, Turck M (1966) Antibiotic susceptibility testing by a standardized single disk method. Tech Bull Regist Med Technol Am Soc Clin Pathol Regist Med Technol 36:49\u201352","journal-title":"Tech Bull Regist Med Technol Am Soc Clin Pathol Regist Med Technol"},{"key":"3130_CR40","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/j.foodcont.2018.08.020","volume":"95","author":"J-R Bai","year":"2019","unstructured":"Bai J-R, Zhong K, Wu Y-P, Elena G, Gao H (2019) Antibiofilm activity of shikimic acid against Staphylococcus aureus. Food Control 95:327\u2013333. https:\/\/doi.org\/10.1016\/j.foodcont.2018.08.020","journal-title":"Food Control"},{"key":"3130_CR41","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1007\/s13205-016-0544-1","volume":"6","author":"K Doriya","year":"2016","unstructured":"Doriya K, Kumar DS (2016) Isolation and screening of L-asparaginase free of glutaminase and urease from fungal sp. 3 Biotech 6:239. https:\/\/doi.org\/10.1007\/s13205-016-0544-1","journal-title":"3 Biotech"},{"key":"3130_CR42","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtcomm.2020.101553","volume":"25","author":"Z Obeizi","year":"2020","unstructured":"Obeizi Z, Benbouzid H, Ouchenane S, Y\u0131lmaz D, Culha M, Bououdina M (2020) Biosynthesis of zinc oxide nanoparticles from essential oil of Eucalyptus globulus with antimicrobial and anti-biofilm activities. Mater Today Commun 25:101553. https:\/\/doi.org\/10.1016\/j.mtcomm.2020.101553","journal-title":"Mater Today Commun"},{"key":"3130_CR43","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.jmrt.2020.12.098","volume":"11","author":"BA Al Jahdaly","year":"2021","unstructured":"Al Jahdaly BA, Al-Radadi NS, Eldin GMG, Almahri A, Ahmed MK, Shoueir K, Janowska I (2021) Selenium nanoparticles synthesized using an eco-friendly method: dye decolorization from aqueous solutions, cell viability, antioxidant, and antibacterial effectiveness. J Mater Res Technol 11:85\u201397. https:\/\/doi.org\/10.1016\/j.jmrt.2020.12.098","journal-title":"J Mater Res Technol"},{"key":"3130_CR44","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1038\/s41598-019-57333-7","volume":"10","author":"M Vahdati","year":"2020","unstructured":"Vahdati M, Tohidi Moghadam T (2020) Synthesis and characterization of selenium nanoparticles-lysozyme nanohybrid system with synergistic antibacterial properties. Sci Rep 10:510. https:\/\/doi.org\/10.1038\/s41598-019-57333-7","journal-title":"Sci Rep"},{"key":"3130_CR45","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1186\/s11671-017-2165-y","volume":"12","author":"F Jiang","year":"2017","unstructured":"Jiang F, Cai W, Tan G (2017) Facile synthesis and optical properties of small selenium nanocrystals and nanorods. Nanoscale Res Lett 12:401. https:\/\/doi.org\/10.1186\/s11671-017-2165-y","journal-title":"Nanoscale Res Lett"},{"key":"3130_CR46","doi-asserted-by":"publisher","first-page":"10086","DOI":"10.1103\/PhysRevB.46.10086","volume":"46","author":"C-Y Yeh","year":"1992","unstructured":"Yeh C-Y, Lu ZW, Froyen S, Zunger A (1992) Zinc-blende\u2013wurtzite polytypism in semiconductors. Phys Rev B 46:10086\u201310097. https:\/\/doi.org\/10.1103\/PhysRevB.46.10086","journal-title":"Phys Rev B"},{"key":"3130_CR47","doi-asserted-by":"publisher","first-page":"19","DOI":"10.30538\/psrp-ojc2018.0003","volume":"1","author":"Z Ahmad","year":"2018","unstructured":"Ahmad Z, UllahKha F, Mahmood S, Mahmood T, Shamim A (2018) Different approaches for the synthesis of zinc oxide nanoparticles. Open J Chem 1:19\u201325. https:\/\/doi.org\/10.30538\/psrp-ojc2018.0003","journal-title":"Open J Chem"},{"key":"3130_CR48","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1016\/j.colsurfb.2011.01.042","volume":"84","author":"CG Kumar","year":"2011","unstructured":"Kumar CG, Mamidyala SK (2011) Extracellular synthesis of silver nanoparticles using culture supernatant of Pseudomonas aeruginosa. Colloids Surf B Biointerfaces 84:462\u2013466. https:\/\/doi.org\/10.1016\/j.colsurfb.2011.01.042","journal-title":"Colloids Surf B Biointerfaces"},{"key":"3130_CR49","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1007\/s00203-023-03467-2","volume":"205","author":"SS Salem","year":"2023","unstructured":"Salem SS (2023) A mini review on green nanotechnology and its development in biological effects. Arch Microbiol 205:128. https:\/\/doi.org\/10.1007\/s00203-023-03467-2","journal-title":"Arch Microbiol"},{"key":"3130_CR50","doi-asserted-by":"publisher","DOI":"10.1016\/j.nxmate.2023.100071","volume":"3","author":"VD Videira","year":"2024","unstructured":"Videira VD, Harada BN, Vital VG, da Silva RAG, de Vasconcellos SP, Pellosi DS (2024) Structural and antibacterial evaluation of copper, silver, and bimetallic silver\/copper nanoalloys synthesized in chitosan biopolymer. Next Mater 3:100071. https:\/\/doi.org\/10.1016\/j.nxmate.2023.100071","journal-title":"Next Mater"},{"key":"3130_CR51","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2023.123111","volume":"642","author":"E Elekhnawy","year":"2023","unstructured":"Elekhnawy E, Almurshedi AS, Abdelkader DH, El-Masry TA, Aldosari BN, El-Bouseary MM, Donia AA, Negm WA (2023) Green synthesised zinc oxide nanoparticles reveal potent in vivo and in vitro antibacterial efficacy against Proteus mirabilis isolates. Int J Pharm 642:123111. https:\/\/doi.org\/10.1016\/j.ijpharm.2023.123111","journal-title":"Int J Pharm"},{"key":"3130_CR52","doi-asserted-by":"publisher","DOI":"10.1016\/j.lwt.2021.110969","volume":"141","author":"MT Yilmaz","year":"2021","unstructured":"Yilmaz MT, \u0130spirli H, Taylan O, Dertli E (2021) A green nano-biosynthesis of selenium nanoparticles with Tarragon extract: Structural, thermal, and antimicrobial characterization. LWT 141:110969. https:\/\/doi.org\/10.1016\/j.lwt.2021.110969","journal-title":"LWT"},{"key":"3130_CR53","doi-asserted-by":"publisher","first-page":"24900","DOI":"10.1039\/d1ra03133c","volume":"11","author":"S Manzoor","year":"2021","unstructured":"Manzoor S, Bashir DJ, Imtiyaz K, Rizvi MMA, Ahamad I, Fatma T, Agarwal NB, Arora I, Samim M (2021) Biofabricated platinum nanoparticles: therapeutic evaluation as a potential nanodrug against breast cancer cells and drug-resistant bacteria. RSC Adv 11:24900\u201324916. https:\/\/doi.org\/10.1039\/d1ra03133c","journal-title":"RSC Adv"},{"key":"3130_CR54","doi-asserted-by":"publisher","first-page":"9578","DOI":"10.1038\/srep09578","volume":"5","author":"M Arakha","year":"2015","unstructured":"Arakha M, Saleem M, Mallick BC, Jha S (2015) The effects of interfacial potential on antimicrobial propensity of ZnO nanoparticle. Sci Rep 5:9578. https:\/\/doi.org\/10.1038\/srep09578","journal-title":"Sci Rep"},{"key":"3130_CR55","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1016\/j.colsurfb.2019.02.013","volume":"177","author":"B Lallo da Silva","year":"2019","unstructured":"Lallo da Silva B, Caetano BL, Chiari-Andr\u00e9o BG, Pietro RCLR, Chiavacci LA (2019) Increased antibacterial activity of ZnO nanoparticles: Influence of size and surface modification. Colloids Surf B Biointerfaces 177:440\u2013447. https:\/\/doi.org\/10.1016\/j.colsurfb.2019.02.013","journal-title":"Colloids Surf B Biointerfaces"},{"key":"3130_CR56","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1016\/j.nano.2010.10.001","volume":"7","author":"M Premanathan","year":"2011","unstructured":"Premanathan M, Karthikeyan K, Jeyasubramanian K, Manivannan G (2011) Selective toxicity of ZnO nanoparticles toward Gram-positive bacteria and cancer cells by apoptosis through lipid peroxidation. Nanomed Nanotechnol Biol Med 7:184\u2013192. https:\/\/doi.org\/10.1016\/j.nano.2010.10.001","journal-title":"Nanomed Nanotechnol Biol Med"},{"key":"3130_CR57","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2023.126171","volume":"250","author":"M Srinivash","year":"2023","unstructured":"Srinivash M, Krishnamoorthi R, Mahalingam PU, Malaikozhundan B (2023) Exopolysaccharide from Lactococcus hircilactis CH4 and Lactobacillus delbrueckii GRIPUMSK as new therapeutics to treat biofilm pathogens, oxidative stress and human colon adenocarcinoma. Int J Biol Macromol 250:126171. https:\/\/doi.org\/10.1016\/j.ijbiomac.2023.126171","journal-title":"Int J Biol Macromol"},{"key":"3130_CR58","doi-asserted-by":"publisher","DOI":"10.1016\/j.jafr.2023.100517","volume":"11","author":"M Srinivash","year":"2023","unstructured":"Srinivash M, Krishnamoorthi R, Mahalingam PU, Malaikozhundan B, Keerthivasan M (2023) Probiotic potential of exopolysaccharide producing lactic acid bacteria isolated from homemade fermented food products. J Agric Food Res 11:100517. https:\/\/doi.org\/10.1016\/j.jafr.2023.100517","journal-title":"J Agric Food Res"},{"key":"3130_CR59","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/j.jtemb.2014.07.020","volume":"29","author":"M Shakibaie","year":"2015","unstructured":"Shakibaie M, Forootanfar H, Golkari Y, Mohammadi-Khorsand T, Shakibaie MR (2015) Anti-biofilm activity of biogenic selenium nanoparticles and selenium dioxide against clinical isolates of Staphylococcus aureus, Pseudomonas aeruginosa, and Proteus mirabilis. J Trace Elem Med Biol 29:235\u2013241. https:\/\/doi.org\/10.1016\/j.jtemb.2014.07.020","journal-title":"J Trace Elem Med Biol"},{"key":"3130_CR60","doi-asserted-by":"publisher","first-page":"5580","DOI":"10.1016\/j.ceramint.2020.10.142","volume":"47","author":"SZ Mirzaei","year":"2021","unstructured":"Mirzaei SZ, Ahmadi Somaghian S, Lashgarian HE, Karkhane M, Cheraghipour K, Marzban A (2021) Phyco-fabrication of bimetallic nanoparticles (zinc\u2013selenium) using aqueous extract of Gracilaria corticata and its biological activity potentials. Ceram Int 47:5580\u20135586. https:\/\/doi.org\/10.1016\/j.ceramint.2020.10.142","journal-title":"Ceram Int"},{"key":"3130_CR61","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics9020059","author":"LK Vestby","year":"2020","unstructured":"Vestby LK, Gr\u00f8nseth T, Simm R, Nesse LL (2020) Bacterial biofilm and its role in the pathogenesis of disease. Antibiotics. https:\/\/doi.org\/10.3390\/antibiotics9020059","journal-title":"Antibiotics"},{"key":"3130_CR62","doi-asserted-by":"publisher","first-page":"1366","DOI":"10.1021\/acscentsci.9b00359","volume":"5","author":"J Wu","year":"2019","unstructured":"Wu J, Li F, Hu X, Lu J, Sun X, Gao J, Ling D (2019) Responsive assembly of silver nanoclusters with a biofilm locally amplified bactericidal effect to enhance treatments against multi-drug-resistant bacterial infections. ACS Cent Sci 5:1366\u20131376. https:\/\/doi.org\/10.1021\/acscentsci.9b00359","journal-title":"ACS Cent Sci"},{"key":"3130_CR63","doi-asserted-by":"publisher","first-page":"12619","DOI":"10.1038\/s41598-021-92006-4","volume":"11","author":"P Singh","year":"2021","unstructured":"Singh P, Pandit S, Jers C, Joshi AS, Garn\u00e6s J, Mijakovic I (2021) Silver nanoparticles produced from Cedecea sp. exhibit antibiofilm activity and remarkable stability. Sci Rep 11:12619. https:\/\/doi.org\/10.1038\/s41598-021-92006-4","journal-title":"Sci Rep"},{"key":"3130_CR64","doi-asserted-by":"publisher","first-page":"4390","DOI":"10.1007\/s10904-021-02053-7","volume":"31","author":"V Beena","year":"2021","unstructured":"Beena V, Ajitha S, Rayar SL, Parvathiraja C, Kannan K, Palani G (2021) Enhanced photocatalytic and antibacterial activities of ZnSe nanoparticles. J Inorg Organomet Polym Mater 31:4390\u20134401. https:\/\/doi.org\/10.1007\/s10904-021-02053-7","journal-title":"J Inorg Organomet Polym Mater"},{"key":"3130_CR65","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1007\/s10930-015-9627-9","volume":"34","author":"S Ponnuvel","year":"2015","unstructured":"Ponnuvel S, Subramanian B, Ponnuraj K (2015) Conformational change results in loss of enzymatic activity of jack bean urease on its interaction with silver nanoparticle. Protein J 34:329\u2013337. https:\/\/doi.org\/10.1007\/s10930-015-9627-9","journal-title":"Protein J"},{"key":"3130_CR66","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1002\/bab.1341","volume":"62","author":"HP Borase","year":"2015","unstructured":"Borase HP, Salunkhe RB, Patil CD, Suryawanshi RK, Salunke BK, Wagh ND, Patil SV (2015) Innovative approach for urease inhibition by Ficus carica extract-fabricated silver nanoparticles: an in vitro study. Biotechnol Appl Biochem 62:780\u2013784. https:\/\/doi.org\/10.1002\/bab.1341","journal-title":"Biotechnol Appl Biochem"},{"key":"3130_CR67","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1007\/s12649-021-01537-4","volume":"13","author":"R Ullah","year":"2022","unstructured":"Ullah R, Azam A, Aziz T, Farhan RHU, Qiao S, Hameed A (2022) Peacock feathers extract use as template for synthesis of Ag and Au nanoparticles and their biological applications. Waste Biomass Valor 13:659\u2013666. https:\/\/doi.org\/10.1007\/s12649-021-01537-4","journal-title":"Waste Biomass Valor"},{"key":"3130_CR68","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1556\/030.64.2017.004","volume":"64","author":"ST Khan","year":"2017","unstructured":"Khan ST, Malik A, Wahab R, Abd-Elkader OH, Ahamed M, Ahmad J, Musarrat J, Siddiqui MA, Al-Khedhairy AA (2017) Synthesis and characterization of some abundant nanoparticles, their antimicrobial and enzyme inhibition activity. Acta Microbiol Immunol Hung 64:203\u2013216. https:\/\/doi.org\/10.1556\/030.64.2017.004","journal-title":"Acta Microbiol Immunol Hung"}],"container-title":["Bioprocess and Biosystems Engineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00449-025-03130-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00449-025-03130-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00449-025-03130-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,22]],"date-time":"2025-03-22T20:28:15Z","timestamp":1742675295000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00449-025-03130-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,5]]},"references-count":68,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["3130"],"URL":"https:\/\/doi.org\/10.1007\/s00449-025-03130-8","relation":{},"ISSN":["1615-7591","1615-7605"],"issn-type":[{"value":"1615-7591","type":"print"},{"value":"1615-7605","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,5]]},"assertion":[{"value":"11 May 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 January 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 February 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that there is no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This declaration is not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The authors provided full consent for publication of the data.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}}]}}