{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T13:43:22Z","timestamp":1790948602227,"version":"4.1.0"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T00:00:00Z","timestamp":1774224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T00:00:00Z","timestamp":1774224000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100011104","name":"Universitat Aut\u00f2noma de Barcelona","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100011104","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bioprocess Biosyst Eng"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1007\/s00449-026-03316-8","type":"journal-article","created":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T08:13:15Z","timestamp":1774253595000},"page":"1287-1302","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Flavonoid production via solid-state fermentation of agro-industrial waste with biopesticidal fungi: screening, optimization and scale-up"],"prefix":"10.1007","volume":"49","author":[{"given":"Fab\u00edola Ribeiro","family":"de Oliveira","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7010-6984","authenticated-orcid":false,"given":"Arnau","family":"Sala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clarissa","family":"Okino-Delgado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Gea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda","family":"Casciatori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,23]]},"reference":[{"key":"3316_CR1","doi-asserted-by":"publisher","unstructured":"Damalas CA, Koutroubas SD (2018) Current Status and Recent Developments in Biopesticide Use, Agriculture. https:\/\/doi.org\/10.1080\/03650340.2017.1387651","DOI":"10.1080\/03650340.2017.1387651"},{"key":"3316_CR2","unstructured":"CropLife Brazil Research. Bioinputs in Brazil Industry Market Data (2024) Accessed on March 2025. Available in: https:\/\/croplifebrasil.org\/wp-content\/uploads\/2024\/06\/CropLife-Brasil-Industry-Market-Data-of-Bioinputs-in-Brazil.pdf"},{"key":"3316_CR3","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.jip.2015.11.011","volume":"133","author":"CA Valero-Jim\u00e9nez","year":"2016","unstructured":"Valero-Jim\u00e9nez CA, Wiegers H, Zwaan BJ, Koenraadt CJM, Van Kan JAL (2016) Genes involved in virulence of the entomopathogenic fungus Beauveria bassiana. J Invertebr Pathol 133:41\u201349. https:\/\/doi.org\/10.1016\/j.jip.2015.11.011","journal-title":"J Invertebr Pathol"},{"key":"3316_CR4","doi-asserted-by":"publisher","DOI":"10.1007\/s11274-016-2131-3","author":"GM Mascarin","year":"2016","unstructured":"Mascarin GM, Jaronski ST (2016) The production and uses of Beauveria bassiana as a microbial insecticide. World J Microbiol Biotechnol. https:\/\/doi.org\/10.1007\/s11274-016-2131-3","journal-title":"World J Microbiol Biotechnol"},{"key":"3316_CR5","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1023\/A:1009625831128","volume":"3","author":"YE Spiegel","year":"1998","unstructured":"Spiegel YE, Chet I (1998) Evaluation of Trichoderma spp. As a biocontrol agent against soilborne fungi and plant-parasitic nematodes in Israel. Integr Pest Manage Reviews Isr 3:169\u2013175. https:\/\/doi.org\/10.1023\/A:1009625831128","journal-title":"Integr Pest Manage Reviews Isr"},{"key":"3316_CR6","doi-asserted-by":"publisher","first-page":"149","DOI":"10.18276\/ab.2020.27-14","volume":"27","author":"E Pourtaghi","year":"2020","unstructured":"Pourtaghi E, Talaei-Hassanloui R, Nasibi F, Fotouhifar K (2020) Endophytic colonization of tomato by Beauveria bassiana for control of the greenhouse whitefly, Trialeurodes vaporariorum (Hemiptera: Aleyrodidae). Acta Biologica 27:149\u2013160. https:\/\/doi.org\/10.18276\/ab.2020.27-14","journal-title":"Acta Biologica"},{"key":"3316_CR7","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28073208","author":"I Ch\u00f3ez-Guaranda","year":"2023","unstructured":"Ch\u00f3ez-Guaranda I, Espinoza-Lozano F, Reyes-Araujo D, Romero C, Manzano P, Galarza L, Sosa D (2023) Chemical Characterization of Trichoderma spp. Extracts with Antifungal Activity against Cocoa Pathogens. Molecules. https:\/\/doi.org\/10.3390\/molecules28073208","journal-title":"Molecules"},{"key":"3316_CR8","doi-asserted-by":"publisher","DOI":"10.3390\/agronomy10081209","author":"A Shah","year":"2020","unstructured":"Shah A, Smith DL (2020) Flavonoids in Agriculture: Chemistry and Roles in, Biotic and Abiotic Stress Responses, and Microbial Associations. Agronomy. https:\/\/doi.org\/10.3390\/agronomy10081209","journal-title":"Agronomy"},{"key":"3316_CR9","doi-asserted-by":"publisher","DOI":"10.1016\/j.cep.2022.108981","author":"MPD Silva","year":"2022","unstructured":"Silva MPD, Dutra RS, Casciatori FP, Grajales LM (2022) A two-phase model for simulation of water transfer during lipase production by solid-state cultivation in a tray bioreactor using babassu residues as substrate. Chem Engeneerign Process \u2013 Process Intensif. https:\/\/doi.org\/10.1016\/j.cep.2022.108981","journal-title":"Chem Engeneerign Process \u2013 Process Intensif"},{"key":"3316_CR10","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1016\/j.biotechadv.2011.01.008","volume":"29","author":"S Martins","year":"2011","unstructured":"Martins S, Mussatto SI, Mart\u00ednez-Avil G, Monta\u00f1ez-Saenz J, Aguilar CN, Teixeira JA (2011) Bioactive phenolic compounds: Production and extraction by solid-state fermentation. A review. Biotechnol Adv 29:365\u2013373. https:\/\/doi.org\/10.1016\/j.biotechadv.2011.01.008","journal-title":"Biotechnol Adv"},{"key":"3316_CR11","unstructured":"Casciatori FP (2015) Produ\u00e7\u00e3o de celulases f\u00fangicas por fermenta\u00e7\u00e3o em estado s\u00f3lido: amplia\u00e7\u00e3o de escala de biorreatores de leito fixo. Tese (Doutorado em Engenharia e Ci\u00eancia de Alimentos, Universidade Estadual Paulista J\u00falio de Mesquita Filho. S\u00e3o Jos\u00e9 do Rio Preto"},{"key":"3316_CR12","doi-asserted-by":"publisher","first-page":"326","DOI":"10.3109\/07388551.2013.857292","volume":"35","author":"C De La Quiroz","year":"2015","unstructured":"De La Quiroz C, Roussos R, Hern\u00e1ndez S, Rodr\u00edguez D, Castillo R, Aguilar F, C.N (2015) Challenges and opportunities of the bio-pesticides production by solid-state fermentation: filamentous fungi as a model. Crit Rev Biotechnol 35:326\u2013333. https:\/\/doi.org\/10.3109\/07388551.2013.857292","journal-title":"Crit Rev Biotechnol"},{"key":"3316_CR13","unstructured":"United Nations Environment Programme (2024) Food Waste Index Report 2024. Available in: https:\/\/brasil.un.org\/sites\/default\/files\/2024-03\/food_waste_index_report_2024_0.pdf Accessed in: March 2025"},{"key":"3316_CR14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jwpe.2024.105904","author":"YA Fonseca","year":"2024","unstructured":"Fonseca YA, Fernandes ARAC, Gurgel LVA, Ba\u00eata BEL (2024) Comparative life cycle assessment of early-stage technological layouts for brewers\u2019 spent grain upcycling: A sustainable approach for adding value to waste. J Water Process Eng. https:\/\/doi.org\/10.1016\/j.jwpe.2024.105904","journal-title":"J Water Process Eng"},{"key":"3316_CR15","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fbioe.2022.870744","volume":"10","author":"A Zeko-Pivac","year":"2022","unstructured":"Zeko-Pivac A, Tisma MA, Znidarsic-Plazl P, Kulisic B, Sakellaris G, Hao J, Planinic M (2022) The potential of brewer\u2019s spent grain in the circular bioeconomy: state of the art and future perspectives. Front Bioeng Biotechnol 10:1\u201315. https:\/\/doi.org\/10.3389\/fbioe.2022.870744","journal-title":"Front Bioeng Biotechnol"},{"key":"3316_CR16","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.scitotenv.2019.04.156","volume":"675","author":"M Kamil","year":"2019","unstructured":"Kamil M, Ramadan KM, Awad OI, Ibrahim TK, Inayat A, Ma X (2019) Environmental impacts of biodiesel production from waste spent coffee grounds and its implementation in a compression ignition engine. Sci Total Environ 675:13\u201330. https:\/\/doi.org\/10.1016\/j.scitotenv.2019.04.156","journal-title":"Sci Total Environ"},{"key":"3316_CR17","doi-asserted-by":"publisher","DOI":"10.1080\/87559129.2015.1041183","author":"CH Okino-Delgado","year":"2016","unstructured":"Okino-Delgado CH, Fleuri LF (2016) Orange and mango by-products: Agro-industrial waste as source of bioactive compounds and botanical versus commercial description\u2014A review. Food Reviews Int. https:\/\/doi.org\/10.1080\/87559129.2015.1041183","journal-title":"Food Reviews Int"},{"key":"3316_CR18","doi-asserted-by":"publisher","DOI":"10.1016\/j.biortech.2019.122322","author":"A Sala","year":"2020","unstructured":"Sala A, Artola A, S\u00e1nchez A, Barrena R (2020) Rice husk as a source for fungal biopesticide production by solid-state fermentation using B. bassiana and T. harzianum. Bioresour Technol. https:\/\/doi.org\/10.1016\/j.biortech.2019.122322","journal-title":"Bioresour Technol"},{"key":"3316_CR19","doi-asserted-by":"publisher","DOI":"10.1080\/10643389.2018.1557497","author":"A Sala","year":"2019","unstructured":"Sala A, Barrena R, Artola A, S\u00e1nchez A (2019) Current developments in the production of fungal biological control agents by solid-state fermentation using organic solid waste. Crit Rev Environ Sci Technol. https:\/\/doi.org\/10.1080\/10643389.2018.1557497","journal-title":"Crit Rev Environ Sci Technol"},{"key":"3316_CR20","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1080\/03650340.2017.1387651","volume":"64","author":"A Cervera-Mata","year":"2018","unstructured":"Cervera-Mata A, Pastoriza S, Rufi\u00b4An-Henares J\u00b4A, P\u00b4Arraga J, Mart\u00edn-Garc\u00eda JM, Delgado G (2018) Impact of spent coffee grounds as organic amendment on soil fertility and lettuce growth in two Mediterranean agricultural soils. Arch Agron Soil Sci 64:790\u2013804. https:\/\/doi.org\/10.1080\/03650340.2017.1387651","journal-title":"Arch Agron Soil Sci"},{"key":"3316_CR21","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/j.scienta.2011.03.040","volume":"129","author":"PA Roussos","year":"2011","unstructured":"Roussos PA (2011) Phytochemicals and antioxidant capacity of orange (Citrus sinensis (l.) Osbeck cv. Salustiana) juice produced under organic and integrated farming system in Greece. Sci Hortic 129:253\u2013258. https:\/\/doi.org\/10.1016\/j.scienta.2011.03.040","journal-title":"Sci Hortic"},{"key":"3316_CR22","doi-asserted-by":"publisher","first-page":"1963","DOI":"10.1007\/s12649-020-01148-5","volume":"12","author":"A Rodr\u00edguez","year":"2021","unstructured":"Rodr\u00edguez A, Gea T, S\u00e1nchez A et al (2021) Agro-wastes and Inert Materials as Supports for the Production of Biosurfactants by Solid-state Fermentation. Waste Biomass Valor 12:1963\u20131976. https:\/\/doi.org\/10.1007\/s12649-020-01148-5","journal-title":"Waste Biomass Valor"},{"key":"3316_CR23","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/j.rser.2015.07.092","volume":"52","author":"CS Farinas","year":"2015","unstructured":"Farinas CS (2015) Developments in solid-state fermentation for the production of biomass-degrading enzymes for the bioenergy sector. Renew Sustain Energy Rev 52:179\u2013188. https:\/\/doi.org\/10.1016\/j.rser.2015.07.092","journal-title":"Renew Sustain Energy Rev"},{"key":"3316_CR24","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-84041998000200004","author":"MD Santos","year":"1998","unstructured":"Santos MD, Blatt CTT (1998) Teor de flavon\u00f3ides e fen\u00f3is totais em folhas de Pyrostegia venusta Miers. de mata e de cerrado. Brazilian J Bot. https:\/\/doi.org\/10.1590\/S0100-84041998000200004","journal-title":"Brazilian J Bot"},{"key":"3316_CR25","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijfoodmicro.2021.109207","author":"AI Rodrigues","year":"2021","unstructured":"Rodrigues AI, Gudi\u00f1a EJ, Abrunhosa L, Malheiro AR, Fernandes R, Teixeira JA, Rodrigues LL (2021) Rhamnolipids inhibit aflatoxins production in Aspergillus flavus by causing structural damages in the fungal hyphae and down-regulating the expression of their biosynthetic genes. Int J Food Microbiol. https:\/\/doi.org\/10.1016\/j.ijfoodmicro.2021.109207","journal-title":"Int J Food Microbiol"},{"key":"3316_CR26","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1016\/j.jclepro.2019.06.211","volume":"234","author":"DZ Prado","year":"2019","unstructured":"Prado DZ, Oliveira SL, Okino-Delgado CH, Auer S, Ludwig-Muller J, Da Silva MR, Fleuri LF (2019) Aspergillus flavipes as a novel biostimulant for rooting-enhancement of Eucalyptus. J Clean Prod 234:681\u2013689. https:\/\/doi.org\/10.1016\/j.jclepro.2019.06.211","journal-title":"J Clean Prod"},{"key":"3316_CR27","doi-asserted-by":"publisher","first-page":"26","DOI":"10.4067\/S0717-34581998000300007","volume":"13","author":"M Raimbault","year":"1998","unstructured":"Raimbault M (1998) General and microbiological aspects of solid substrate fermentation. Electron J Biotechnol 13:26\u201327. https:\/\/doi.org\/10.4067\/S0717-34581998000300007","journal-title":"Electron J Biotechnol"},{"issue":"2","key":"3316_CR28","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1002\/jsfa.2740640204","volume":"64","author":"CE Lister","year":"1994","unstructured":"Lister CE, Lancaster JE, Sutton KH, Walker JR (1994) Developmental changes in the concentration and composition of flavonoids in skin of a red and a green apple cultivar. J Sci Food Agric 64(2):155\u2013161. https:\/\/doi.org\/10.1002\/jsfa.2740640204","journal-title":"J Sci Food Agric"},{"key":"3316_CR29","doi-asserted-by":"publisher","first-page":"161","DOI":"10.2134\/jeq2009.0294","volume":"165","author":"B Puyuelo","year":"2010","unstructured":"Puyuelo B, Gea T, S\u00e1nchez A (2010) A new control strategy for the composting process based on the oxygen uptake rate. Chem Eng J 165:161\u2013169. https:\/\/doi.org\/10.2134\/jeq2009.0294","journal-title":"Chem Eng J"},{"key":"3316_CR30","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/j.biortech.2018.04.106","volume":"263","author":"O Mart\u00ednez","year":"2018","unstructured":"Mart\u00ednez O, S\u00e1nchez A, Font X, Barrena R (2018) Enhancing the bioproduction of value-added aroma compounds via solid-state fermentation of sugarcane bagasse and sugar beet molasses: Operational strategies and scaling-up of the process. Bioresour Technol 263:136\u2013144. https:\/\/doi.org\/10.1016\/j.biortech.2018.04.106","journal-title":"Bioresour Technol"},{"key":"3316_CR31","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2021.131620","author":"A Sala","year":"2021","unstructured":"Sala A, Barrena R, Sanchez A, Artola A (2021) Fungal biopesticide production: process scale-up and sequential batch mode operation with Trichoderma harzianum using agro-industrial solid wastes of different biodegradability. Chem Eng J. https:\/\/doi.org\/10.1016\/j.cej.2021.131620","journal-title":"Chem Eng J"},{"key":"3316_CR32","volume-title":"Test Methods for the Examination of Composting and Compost","author":"U.S. Composting Council","year":"2001","unstructured":"U.S. Composting Council (2001) Test Methods for the Examination of Composting and Compost. Edaphos International, Houston"},{"key":"3316_CR33","doi-asserted-by":"publisher","first-page":"1372","DOI":"10.1021\/bp0499505","volume":"20","author":"TL Richard","year":"2004","unstructured":"Richard TL, Veeken AHM, De Wilde V, Hamelers HVM (2004) Air-filled porosity and permeability relationships during solid-state fermentation. Biotechnol Prog 20:1372\u20131381. https:\/\/doi.org\/10.1021\/bp0499505","journal-title":"Biotechnol Prog"},{"key":"3316_CR34","doi-asserted-by":"publisher","first-page":"1656","DOI":"10.1021\/ac60083a023","volume":"11","author":"TA Scott Jr","year":"1953","unstructured":"Scott TA Jr, Melvin EH (1953) Determination of dextran with anthrone. Anal Chem 11:1656\u20131661. https:\/\/doi.org\/10.1021\/ac60083a023","journal-title":"Anal Chem"},{"key":"3316_CR35","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/s0032-9592(01)00198-4","volume":"37","author":"K Lachhab","year":"2001","unstructured":"Lachhab K, Tyagi RD, Val\u00e9ro JR (2001) Production of Bacillus thuringiensis biopesticides using wastewater sludge as a raw material: effect of inoculum and sludge solids concentration. Process Biochem 37:197\u20132028. https:\/\/doi.org\/10.1016\/s0032-9592(01)00198-4","journal-title":"Process Biochem"},{"key":"3316_CR36","doi-asserted-by":"publisher","DOI":"10.1016\/j.jenvman.2021.113113","author":"A Sala","year":"2021","unstructured":"Sala A, Vittone S, Barrena R, S\u00e1nchez A, Artola A (2021) Scanning agro-industrial wastes as substrates for fungal biopesticides production: Use of Beauveria bassiana and Trichoderma harzianum in solid-state fermentation. J Environ Manage. https:\/\/doi.org\/10.1016\/j.jenvman.2021.113113","journal-title":"J Environ Manage"},{"key":"3316_CR37","unstructured":"MEYER MC, MAZARO SM, SILVA JC (2019) Trichoderma: uso na agricultura. Embrapa"},{"issue":"1","key":"3316_CR38","doi-asserted-by":"publisher","first-page":"511","DOI":"10.15406\/jabb.2017.04.00094","volume":"4","author":"MA Manan","year":"2017","unstructured":"Manan MA, Webb C (2017) Design aspects of solid state fermentation as applied to microbial bioprocessing. J Appl Biotechnol Bioeng 4(1):511\u2013532. https:\/\/doi.org\/10.15406\/jabb.2017.04.00094","journal-title":"J Appl Biotechnol Bioeng"},{"key":"3316_CR39","doi-asserted-by":"publisher","DOI":"10.1016\/j.ifset.2023.103308","author":"Q Zhao","year":"2023","unstructured":"Zhao Q, Yan X, Yue Y, Yue T, Yuan Y (2023) Improved flavonoid content in mulberry leaves by solid-state fermentation: Metabolic profile, activity, and mechanism. Innovative Food Sci Emerg Technol. https:\/\/doi.org\/10.1016\/j.ifset.2023.103308","journal-title":"Innovative Food Sci Emerg Technol"},{"key":"3316_CR40","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.foodchem.2016.04.016","volume":"209","author":"FV Dulf","year":"2016","unstructured":"Dulf FV, Vodnar DC, Socaciu C (2016) Effects of solid-state fermentation with two filamentous fungi on the total phenolic contents, flavonoids, antioxidant activities and lipid fractions of plum fruit (Prunus domestica L.) by-products. Food Chem 209:27\u201336. https:\/\/doi.org\/10.1016\/j.foodchem.2016.04.016","journal-title":"Food Chem"},{"key":"3316_CR41","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.ces.2018.05.024","volume":"188","author":"FP Casciatori","year":"2018","unstructured":"Casciatori FP, Thom\u00e9o JC (2018) Heat transfer in packed-beds of agricultural waste with low rates of air flow applicable to solid-state fermentation. Chem Eng Sci 188:97\u2013111. https:\/\/doi.org\/10.1016\/j.ces.2018.05.024","journal-title":"Chem Eng Sci"},{"issue":"3","key":"3316_CR42","doi-asserted-by":"publisher","first-page":"872","DOI":"10.3390\/pr11030872","volume":"11","author":"DA Mitchell","year":"2023","unstructured":"Mitchell DA, Ruiz HA, Krieger N (2023) A critical evaluation of recent studies on packed-bed bioreactors for solid-state fermentation. Processes 11(3):872. https:\/\/doi.org\/10.3390\/pr11030872","journal-title":"Processes"},{"key":"3316_CR43","unstructured":"Koppert Description about Trichodermil. Available in: https:\/\/www.koppert.com.br\/trichodermil\/ Accessed in March 2025"},{"key":"3316_CR44","unstructured":"Biotrop Description about NatuControl. Available in: https:\/\/biotrop.com.br\/produto\/natucontrol\/. Accessed in March 2025"}],"container-title":["Bioprocess and Biosystems Engineering"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00449-026-03316-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00449-026-03316-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00449-026-03316-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T20:41:23Z","timestamp":1781642483000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00449-026-03316-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,23]]},"references-count":44,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["3316"],"URL":"https:\/\/doi.org\/10.1007\/s00449-026-03316-8","relation":{},"ISSN":["1615-7591","1615-7605"],"issn-type":[{"value":"1615-7591","type":"print"},{"value":"1615-7605","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,23]]},"assertion":[{"value":"17 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}