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Currently, coughing is assessed perceptually or aerodynamically. The goal of our research is to develop methods of acoustic cough analysis. In this study, we examined in a healthy population the acoustical differences between three protective maneuvers: voluntary cough, voluntary throat clearing, and induced reflexive cough. Forty healthy participants were included in this study. Voluntary cough, voluntary throat clearing, and reflexive cough samples were recorded and analyzed acoustically.\u00a0Temporal acoustic features were the following: the slope and curvature of the amplitude contour, as well as the average, slope, and curvature of the sample entropy and kurtosis contours of the recorded signal. Spectral features were the relative energy in the frequency bands (0\u2013400\u00a0Hz, 400\u2013800\u00a0Hz, 800\u20131600\u00a0Hz, 1600\u00a0Hz-3200\u00a0Hz,\u2009&gt;\u20093200\u00a0Hz) as well as the weighted spectral energy. Results showed that, compared to a voluntary cough, a throat clearing starts with a weaker onset pulse and involves oscillations from the onset to the offset (concave curvature of the amplitude contour,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05), lower average (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05), and slope (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05) as well as lower convex curvature (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05) of the kurtosis contour. An induced reflexive cough starts with a higher and briefer onset burst and includes higher frication noise (larger convexity of the curvature of the amplitude and kurtosis contours (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05)) compared to a voluntary cough. The conclusion is that voluntary coughs are acoustically significantly different from voluntary throat clearings and induced reflexive coughs.\n                  <\/jats:p>","DOI":"10.1007\/s00455-023-10574-1","type":"journal-article","created":{"date-parts":[[2023,5,28]],"date-time":"2023-05-28T04:02:01Z","timestamp":1685246521000},"page":"1467-1486","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Acoustic Analysis of Voluntary Coughs, Throat Clearings, and Induced Reflexive Coughs in a Healthy Population"],"prefix":"10.1007","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4917-7360","authenticated-orcid":false,"given":"Sofiana","family":"Mootassim-Billah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Schoentgen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"De Bodt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Roper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Digonnet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathilde","family":"Le Tensorer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwen","family":"Van Nuffelen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk","family":"Van Gestel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,5,28]]},"reference":[{"key":"10574_CR1","volume-title":"Speech pathology management of chronic refractory cough and related disorders","author":"AE Vertigan","year":"2016","unstructured":"Vertigan AE, Gibson PG. 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