{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T01:22:16Z","timestamp":1783041736395,"version":"3.54.6"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:00:00Z","timestamp":1783036800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:00:00Z","timestamp":1783036800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Dysphagia"],"DOI":"10.1007\/s00455-026-10975-y","type":"journal-article","created":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T01:08:58Z","timestamp":1783040938000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Exploring the Relationship Between Cerebral Blood Flow and Oral Exercise Using Head-Mounted Near-Infrared Spectroscopy"],"prefix":"10.1007","author":[{"given":"Chun-Hsien","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Chou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chia-Chih","family":"Kuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo-Xian","family":"Ou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bor-Shyh","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willy","family":"Chou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,3]]},"reference":[{"issue":"3","key":"10975_CR1","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1111\/ggi.12006","volume":"13","author":"Y Kimura","year":"2013","unstructured":"Kimura Y, Ogawa H, Yoshihara A, Yamaga T, Takiguchi T, Wada T, et al. Evaluation of chewing ability and its relationship with activities of daily living, depression, cognitive status and food intake in the community-dwelling elderly. Geriatr Gerontol Int. 2013;13(3):718\u201325.","journal-title":"Geriatr Gerontol Int"},{"key":"10975_CR2","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1016\/j.archger.2016.12.006","volume":"70","author":"A Tada","year":"2017","unstructured":"Tada A, Miura H. Association between mastication and cognitive status: a systematic review. Arch Gerontol Geriatr. 2017;70:44\u201353.","journal-title":"Arch Gerontol Geriatr"},{"key":"10975_CR3","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/j.jdsr.2023.10.001","volume":"59","author":"MT Sta. Maria","year":"2023","unstructured":"Sta. Maria MT, Hasegawa Y, Khaing AMM, Salazar S, Ono T. The relationships between mastication and cognitive function: A systematic review and meta-analysis. Jpn Dent Sci Rev. 2023;59:375\u201388.","journal-title":"Jpn Dent Sci Rev"},{"issue":"8","key":"10975_CR4","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1046\/j.1365-2842.2003.01124.x","volume":"30","author":"H Miura","year":"2003","unstructured":"Miura H, Yamasaki K, Kariyasu M, Miura K, Sumi Y. Relationship between cognitive function and mastication in elderly females. J Oral Rehabil. 2003;30(8):808\u201311.","journal-title":"J Oral Rehabil"},{"issue":"10","key":"10975_CR5","doi-asserted-by":"publisher","first-page":"1951","DOI":"10.1111\/j.1532-5415.2012.04154.x","volume":"60","author":"D Lexomboon","year":"2012","unstructured":"Lexomboon D, Trulsson M, W\u00e5rdh I, Parker MG. Chewing ability and tooth loss: association with cognitive impairment in an elderly population study. J Am Geriatr Soc. 2012;60(10):1951\u20136.","journal-title":"J Am Geriatr Soc"},{"issue":"3","key":"10975_CR6","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1016\/j.bandc.2012.12.002","volume":"81","author":"Y Hirano","year":"2013","unstructured":"Hirano Y, Obata T, Takahashi H, Tachibana A, Kuroiwa D, Takahashi T, et al. Effects of chewing on cognitive processing speed. Brain Cogn. 2013;81(3):376\u201381.","journal-title":"Brain Cogn"},{"issue":"3","key":"10975_CR7","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1016\/j.neubiorev.2010.06.002","volume":"35","author":"R Weijenberg","year":"2011","unstructured":"Weijenberg R, Scherder E, Lobbezoo F. Mastication for the mind\u2014the relationship between mastication and cognition in ageing and dementia. Neurosci Biobehav Rev. 2011;35(3):483\u201397.","journal-title":"Neurosci Biobehav Rev"},{"issue":"10","key":"10975_CR8","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1007\/s11910-013-0384-x","volume":"13","author":"JM Noble","year":"2013","unstructured":"Noble JM, Scarmeas N, Papapanou PN. Poor oral health as a chronic, potentially modifiable dementia risk factor: review of the literature. Curr Neurol Neurosci Rep. 2013;13(10):384.","journal-title":"Curr Neurol Neurosci Rep"},{"issue":"1","key":"10975_CR9","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1038\/jcbfm.2009.188","volume":"30","author":"OB Paulson","year":"2010","unstructured":"Paulson OB, Hasselbalch SG, Rostrup E, Knudsen GM, Pelligrino D. Cerebral blood flow response to functional activation. J Cereb Blood Flow Metab. 2010;30(1):2\u201314.","journal-title":"J Cereb Blood Flow Metab"},{"issue":"9","key":"10975_CR10","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1001\/archneur.1975.00490510088009","volume":"32","author":"VC Hachinski","year":"1975","unstructured":"Hachinski VC, Iliff LD, Zilhka E, Du Boulay GH, McAllister VL, Marshall J, et al. Cerebral blood flow in dementia. Arch Neurol. 1975;32(9):632\u20137.","journal-title":"Arch Neurol"},{"key":"10975_CR11","doi-asserted-by":"publisher","first-page":"599","DOI":"10.2147\/VHRM.S34874","volume":"8","author":"AE Roher","year":"2012","unstructured":"Roher AE, Debbins JP, Malek-Ahmadi M, Chen K, Pipe JG, Maze S, et al. Cerebral blood flow in Alzheimer\u2019s disease. Vasc Health Risk Manag. 2012;8:599\u2013611.","journal-title":"Vasc Health Risk Manag"},{"issue":"3","key":"10975_CR12","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1007\/s12576-017-0525-0","volume":"67","author":"S Ogoh","year":"2017","unstructured":"Ogoh S. Relationship between cognitive function and regulation of cerebral blood flow. J Physiol Sci. 2017;67(3):345\u201351.","journal-title":"J Physiol Sci"},{"key":"10975_CR13","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2021.101450","volume":"71","author":"H Zhang","year":"2021","unstructured":"Zhang H, Wang Y, Lyu D, Li Y, Li W, Wang Q, et al. Cerebral blood flow in mild cognitive impairment and Alzheimer\u2019s disease: A systematic review and meta-analysis. Ageing Res Rev. 2021;71:101450.","journal-title":"Ageing Res Rev"},{"issue":"4","key":"10975_CR14","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1203\/00006450-199810000-00020","volume":"44","author":"M Tsuji","year":"1998","unstructured":"Tsuji M, Duplessis A, Taylor G, Crocker R, Volpe JJ. Near infrared spectroscopy detects cerebral ischemia during hypotension in piglets. Pediatr Res. 1998;44(4):591\u20135.","journal-title":"Pediatr Res"},{"issue":"4","key":"10975_CR15","doi-asserted-by":"publisher","first-page":"2117","DOI":"10.1364\/BOE.10.002117","volume":"10","author":"T Pham","year":"2019","unstructured":"Pham T, Tgavalekos K, Sassaroli A, Blaney G, Fantini S. Quantitative measurements of cerebral blood flow with near-infrared spectroscopy. Biomed Opt Express. 2019;10(4):2117\u201334.","journal-title":"Biomed Opt Express"},{"issue":"4","key":"10975_CR16","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1203\/00006450-200010000-00005","volume":"48","author":"JS Soul","year":"2000","unstructured":"Soul JS, Taylor GA, Wypij D, Duplessis AJ, Volpe JJ. Noninvasive detection of changes in cerebral blood flow by near-infrared spectroscopy in a piglet model of hydrocephalus. Pediatr Res. 2000;48(4):445\u20139.","journal-title":"Pediatr Res"},{"issue":"2","key":"10975_CR17","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1203\/01.PDR.0000148714.51310.5E","volume":"57","author":"A Pryds","year":"2005","unstructured":"Pryds A, T\u00f8nnesen J, Pryds O, Knudsen GM, Greisen G. Cerebral pressure autoregulation and vasoreactivity in the newborn rat. Pediatr Res. 2005;57(2):294\u20138.","journal-title":"Pediatr Res"},{"issue":"1","key":"10975_CR18","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/s12877-017-0693-z","volume":"18","author":"C-s Lin","year":"2018","unstructured":"Lin C-s. Revisiting the link between cognitive decline and masticatory dysfunction. BMC Geriatr. 2018;18(1):5.","journal-title":"BMC Geriatr"},{"issue":"1","key":"10975_CR19","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1177\/0031512516683074","volume":"124","author":"T Yokoyama","year":"2017","unstructured":"Yokoyama T, Sato M, Natsui S, Kuboyama N, Suzuki K, Inaba H, et al. Effect of gum chewing frequency on oxygenation of the prefrontal cortex. Percept Mot Skills. 2017;124(1):58\u201371.","journal-title":"Percept Mot Skills"},{"issue":"1","key":"10975_CR20","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/S0003-9969(96)00081-7","volume":"42","author":"T Momose","year":"1997","unstructured":"Momose T, Nishikawa J, Watanabe T, Sasaki Y, Senda M, Kubota K, et al. Effect of mastication on regional cerebral blood flow in humans examined by positron-emission tomography with 15O-labelled water and magnetic resonance imaging. Arch Oral Biol. 1997;42(1):57\u201361.","journal-title":"Arch Oral Biol"},{"key":"10975_CR21","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2021.649910","volume":"15","author":"TG White","year":"2021","unstructured":"White TG, Powell K, Shah KA, Woo HH, Narayan RK, Li C. Trigeminal nerve control of cerebral blood flow: a brief review. Front Neurosci. 2021;15:649910.","journal-title":"Front Neurosci"},{"issue":"5","key":"10975_CR22","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1136\/acupmed-2016-011247","volume":"35","author":"H Waki","year":"2017","unstructured":"Waki H, Suzuki T, Tanaka Y, Tamai H, Minakawa Y, Miyazaki S, et al. Effects of electroacupuncture to the trigeminal nerve area on the autonomic nervous system and cerebral blood flow in the prefrontal cortex. Acupunct Med. 2017;35(5):339\u201344.","journal-title":"Acupunct Med"},{"key":"10975_CR23","doi-asserted-by":"publisher","first-page":"174480692090189","DOI":"10.1177\/1744806920901890","volume":"16","author":"E Gambeta","year":"2020","unstructured":"Gambeta E, Chichorro JG, Zamponi GW. Trigeminal neuralgia: An overview from pathophysiology to pharmacological treatments. Mol Pain. 2020;16:1744806920901890.","journal-title":"Mol Pain"},{"issue":"12","key":"10975_CR24","doi-asserted-by":"publisher","first-page":"1440","DOI":"10.1016\/j.archoralbio.2011.04.005","volume":"56","author":"L Avivi-Arber","year":"2011","unstructured":"Avivi-Arber L, Martin R, Lee J-C, Sessle BJ. Face sensorimotor cortex and its neuroplasticity related to orofacial sensorimotor functions. Arch Oral Biol. 2011;56(12):1440\u201365.","journal-title":"Arch Oral Biol"},{"issue":"1","key":"10975_CR25","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1177\/154411130201300109","volume":"13","author":"KS T\u00fcrker","year":"2002","unstructured":"T\u00fcrker KS. Reflex control of human jaw muscles. Crit Rev Oral Biol Med. 2002;13(1):85\u2013104.","journal-title":"Crit Rev Oral Biol Med"},{"issue":"1","key":"10975_CR26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00455-023-10596-9","volume":"39","author":"CF Ross","year":"2024","unstructured":"Ross CF, Laurence-Chasen JD, Li P, Orsbon C, Hatsopoulos NG. Biomechanical and cortical control of tongue movements during chewing and swallowing. Dysphagia. 2024;39(1):1\u201332.","journal-title":"Dysphagia"},{"issue":"4","key":"10975_CR27","doi-asserted-by":"publisher","first-page":"2428","DOI":"10.1152\/jn.01144.2003","volume":"92","author":"RE Martin","year":"2004","unstructured":"Martin RE, MacIntosh BJ, Smith RC, Barr AM, Stevens TK, Gati JS, et al. Cerebral areas processing swallowing and tongue movement are overlapping but distinct: a functional magnetic resonance imaging study. J Neurophysiol. 2004;92(4):2428\u201343.","journal-title":"J Neurophysiol"},{"issue":"8","key":"10975_CR28","doi-asserted-by":"publisher","first-page":"2426","DOI":"10.1002\/hbm.20680","volume":"30","author":"P S\u00f6r\u00f6s","year":"2009","unstructured":"S\u00f6r\u00f6s P, Inamoto Y, Martin RE. Functional brain imaging of swallowing: an activation likelihood estimation meta-analysis. Hum Brain Mapp. 2009;30(8):2426\u201339.","journal-title":"Hum Brain Mapp"},{"issue":"10","key":"10975_CR29","doi-asserted-by":"publisher","first-page":"3209","DOI":"10.1002\/hbm.20743","volume":"30","author":"GA Malandraki","year":"2009","unstructured":"Malandraki GA, Sutton BP, Perlman AL, Karampinos DC, Conway C. Neural activation of swallowing and swallowing-related tasks in healthy young adults: an attempt to separate the components of deglutition. Hum Brain Mapp. 2009;30(10):3209\u201326.","journal-title":"Hum Brain Mapp"},{"issue":"3","key":"10975_CR30","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1007\/BF01354538","volume":"8","author":"RE Martin","year":"1993","unstructured":"Martin RE, Sessle BJ. The role of the cerebral cortex in swallowing. Dysphagia. 1993;8(3):195\u2013202.","journal-title":"Dysphagia"},{"issue":"6","key":"10975_CR31","doi-asserted-by":"publisher","first-page":"2674","DOI":"10.1044\/2025_JSLHR-24-00749","volume":"68","author":"RH Arkenberg","year":"2025","unstructured":"Arkenberg RH, Mitchell S, Venkatraman A, Sivasankar MP, Pearson WG Jr, Malandraki GA. Maximum vocal pitch elevation and swallowing: a secondary data analysis supporting additional shared biomechanics and potential treatment targets. J Speech Lang Hear Res. 2025;68(6):2674\u201384.","journal-title":"J Speech Lang Hear Res"},{"issue":"4","key":"10975_CR32","doi-asserted-by":"publisher","first-page":"1243","DOI":"10.1044\/2014_JSLHR-S-13-0168","volume":"57","author":"KV Miloro","year":"2014","unstructured":"Miloro KV, Pearson WG Jr, Langmore SE. Effortful pitch glide: a potential new exercise evaluated by dynamic MRI. J Speech Lang Hear Res. 2014;57(4):1243\u201350.","journal-title":"J Speech Lang Hear Res"},{"issue":"10","key":"10975_CR33","doi-asserted-by":"publisher","first-page":"3408","DOI":"10.1044\/2020_JSLHR-20-00125","volume":"63","author":"A Venkatraman","year":"2020","unstructured":"Venkatraman A, Fujiki RB, Craig BA, Sivasankar MP, Malandraki GA. Determining the underlying relationship between swallowing and maximum vocal pitch elevation: a preliminary study of their hyoid biomechanics in healthy adults. J Speech Lang Hear Res. 2020;63(10):3408\u201318.","journal-title":"J Speech Lang Hear Res"},{"issue":"9","key":"10975_CR34","doi-asserted-by":"publisher","first-page":"2531","DOI":"10.1161\/STROKEAHA.108.514877","volume":"39","author":"KM Brady","year":"2008","unstructured":"Brady KM, Lee JK, Kibler KK, Easley RB, Koehler RC, Shaffner DH. Continuous measurement of autoregulation by spontaneous fluctuations in cerebral perfusion pressure: comparison of 3 methods. Stroke. 2008;39(9):2531\u20137.","journal-title":"Stroke"},{"key":"10975_CR35","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.jneumeth.2018.09.003","volume":"309","author":"RB Govindan","year":"2018","unstructured":"Govindan RB, Massaro AN, du Plessis A. Ensuring signal quality of cerebral near infrared spectroscopy during continuous longterm monitoring. J Neurosci Methods. 2018;309:147\u201352.","journal-title":"J Neurosci Methods"},{"issue":"1","key":"10975_CR36","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1203\/01.PDR.0000147576.84092.F9","volume":"57","author":"H Bassan","year":"2005","unstructured":"Bassan H, Gauvreau K, Newburger JW, Tsuji M, Limperopoulos C, Soul JS, et al. Identification of pressure passive cerebral perfusion and its mediators after infant cardiac surgery. Pediatr Res. 2005;57(1):35\u201341.","journal-title":"Pediatr Res"},{"key":"10975_CR37","doi-asserted-by":"publisher","first-page":"934731","DOI":"10.3389\/fphys.2022.934731","volume":"13","author":"A Gomez","year":"2022","unstructured":"Gomez A, Sainbhi AS, Froese L, Batson C, Slack T, Stein KY, et al. The quantitative associations between near infrared spectroscopic cerebrovascular metrics and cerebral blood flow: a scoping review of the human and animal literature. Front Physiol. 2022;13:934731.","journal-title":"Front Physiol"},{"issue":"12","key":"10975_CR38","doi-asserted-by":"publisher","first-page":"466","DOI":"10.3390\/jcm7120466","volume":"7","author":"F Herold","year":"2018","unstructured":"Herold F, Wiegel P, Scholkmann F, M\u00fcller NG. Applications of functional near-infrared spectroscopy (fNIRS) neuroimaging in exercise-cognition science: a systematic, methodology-focused review. J Clin Med. 2018;7(12):466.","journal-title":"J Clin Med"}],"container-title":["Dysphagia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00455-026-10975-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00455-026-10975-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00455-026-10975-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T01:08:59Z","timestamp":1783040939000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00455-026-10975-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,3]]},"references-count":38,"alternative-id":["10975"],"URL":"https:\/\/doi.org\/10.1007\/s00455-026-10975-y","relation":{},"ISSN":["0179-051X","1432-0460"],"issn-type":[{"value":"0179-051X","type":"print"},{"value":"1432-0460","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,3]]},"assertion":[{"value":"10 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 March 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 June 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 July 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"There is no conflict of interest, financial, professional or otherwise, between the authors of this study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interests"}}]}}