{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:45:18Z","timestamp":1790790318317,"version":"4.1.0"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,4,11]],"date-time":"2019-04-11T00:00:00Z","timestamp":1554940800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2019,4,11]],"date-time":"2019-04-11T00:00:00Z","timestamp":1554940800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Surg Endosc"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Hemodynamic instability is frequently observed during adrenalectomy for pheochromocytoma (PCC). Guidelines recommend liberal preoperative volume administration. However, it is unclear whether fluid deficiency or vasoplegia causes shifting hemodynamics and whether minimally invasive hemodynamic monitoring with esophageal Doppler (EDM) can help visualize intraoperative changes avoiding volume overload and complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Ten patients with biochemically verified PCC and five patients with hormonally inactive adrenal tumors (HIAT; control group) were treated following a strict protocol. During laparoscopic adrenalectomy, goal-directed fluid therapy was performed using EDM. Hemodynamic and biochemical data were documented. The primary outcome variables were fluid requirement and hemodynamic parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Applying EDM, total intraoperative fluid administration was slightly higher in PCC patients than in patients with HIAT (2100\u2009\u00b1\u2009516 vs. 1550\u2009\u00b1\u2009622\u00a0ml,<jats:italic>p\u2009<\/jats:italic>=\u20090.097; 12.9\u2009\u00b1\u20094.8 vs. 8.3\u2009\u00b1\u20090.7\u00a0ml\u00a0kg<jats:sup>\u22121<\/jats:sup>h<jats:sup>\u22121<\/jats:sup>,<jats:italic>p\u2009<\/jats:italic>=\u20090.014). Hemodynamics varied considerably within the PCC group and was associated with type and level of secreted catecholamines. Arterial blood pressure and systemic vascular resistance index reached their minimum in the 10-min period after resection of PCC. Without liberal fluid administration, an increase in cardiac index was observed in both groups comparing baseline measurements to end of surgery. This increase was statistically significant only in PCC patients (PCC: 2.31 vs. 3.15\u00a0l\u00a0min<jats:sup>\u22121<\/jats:sup>m<jats:sup>\u22122<\/jats:sup>,<jats:italic>p\u2009<\/jats:italic>=\u20090.005; HIAT: 2.08 vs. 2.56\u00a0l\u00a0min<jats:sup>\u22121<\/jats:sup>m<jats:sup>\u22122<\/jats:sup>,<jats:italic>p\u2009<\/jats:italic>=\u20090.225).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>As vasoplegia, but not hypovolemia, was documented after tumor resection, there is no evidence that PCC patients profit from liberal fluid administration during laparoscopic adrenalectomy. To avoid volume overload, noninvasive techniques such as EDM should be routinely used to visualize the variable intraoperative course.<\/jats:p><jats:p>Trial registration: ClinicalTrials.gov, Identifier: NCT01425710.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00464-019-06777-z","type":"journal-article","created":{"date-parts":[[2019,4,11]],"date-time":"2019-04-11T16:04:37Z","timestamp":1554998677000},"page":"368-376","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["The determination of real fluid requirements in laparoscopic resection of pheochromocytoma using minimally invasive hemodynamic monitoring: a prospectively designed trial"],"prefix":"10.1007","volume":"34","clinical-trial-number":[{"clinical-trial-number":"nct01425710","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0450-6132","authenticated-orcid":false,"given":"Martin B.","family":"Niederle","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edith","family":"Fleischmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Kabon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Niederle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,4,11]]},"reference":[{"key":"6777_CR1","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.ejim.2018.01.015","volume":"51","author":"AMA Berends","year":"2018","unstructured":"Berends AMA, Buitenwerf E, de Krijger RR, Veeger N, van der Horst-Schrivers ANA, Links TP, Kerstens MN (2018) Incidence of pheochromocytoma and sympathetic paraganglioma in the Netherlands: a nationwide study and systematic review. Eur J Intern Med 51:68\u201373","journal-title":"Eur J Intern Med"},{"key":"6777_CR2","doi-asserted-by":"publisher","unstructured":"Ebbehoj A, Sondergaard E, Trolle C, Stochholm K, Poulsen P (2017) The epidemiology of pheochromocytoma: increasing incidence and changing clinical presentation. A population-based retrospective study 1977\u20132015. Endocrine Abstracts 49. https:\/\/doi.org\/10.1530\/endoabs.49.OC1.4","DOI":"10.1530\/endoabs.49.OC1.4"},{"key":"6777_CR3","doi-asserted-by":"publisher","first-page":"1915","DOI":"10.1210\/jc.2014-1498","volume":"99","author":"JW Lenders","year":"2014","unstructured":"Lenders JW, Duh QY, Eisenhofer G, Gimenez-Roqueplo AP, Grebe SK, Murad MH, Naruse M, Pacak K, Young WF Jr, Endocrine S (2014) Pheochromocytoma and paraganglioma: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 99:1915\u20131942","journal-title":"J Clin Endocrinol Metab"},{"key":"6777_CR4","doi-asserted-by":"publisher","first-page":"1208","DOI":"10.1245\/s10434-016-5701-6","volume":"24","author":"T Beninato","year":"2017","unstructured":"Beninato T, Kluijfhout WP, Drake FT, Lim J, Kwon JS, Xiong M, Shen WT, Gosnell JE, Liu C, Suh I, Duh QY (2017) Resection of pheochromocytoma improves diabetes mellitus in the majority of patients. Ann Surg Oncol 24:1208\u20131213","journal-title":"Ann Surg Oncol"},{"key":"6777_CR5","doi-asserted-by":"publisher","first-page":"2984","DOI":"10.1007\/s00464-015-4587-x","volume":"30","author":"S Gaujoux","year":"2016","unstructured":"Gaujoux S, Bonnet S, Lentschener C, Thillois JM, Duboc D, Bertherat J, Samama CM, Dousset B (2016) Preoperative risk factors of hemodynamic instability during laparoscopic adrenalectomy for pheochromocytoma. Surg Endosc 30:2984\u20132993","journal-title":"Surg Endosc"},{"key":"6777_CR6","doi-asserted-by":"publisher","first-page":"4175","DOI":"10.1245\/s10434-015-4519-y","volume":"22","author":"M Livingstone","year":"2015","unstructured":"Livingstone M, Duttchen K, Thompson J, Sunderani Z, Hawboldt G, Sarah Rose M, Pasieka J (2015) Hemodynamic stability during pheochromocytoma resection: lessons learned over the last two decades. Ann Surg Oncol 22:4175\u20134180","journal-title":"Ann Surg Oncol"},{"key":"6777_CR7","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.urology.2016.10.012","volume":"100","author":"TN Weingarten","year":"2017","unstructured":"Weingarten TN, Welch TL, Moore TL, Walters GF, Whipple JL, Cavalcante A, Bancos I, Young WF Jr, Gruber LM, Shah MZ, McKenzie TJ, Schroeder DR, Sprung J (2017) Preoperative levels of catecholamines and metanephrines and intraoperative hemodynamics of patients undergoing pheochromocytoma and paraganglioma resection. Urology 100:131\u2013138","journal-title":"Urology"},{"key":"6777_CR8","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1213\/00000539-199901000-00004","volume":"88","author":"JL Joris","year":"1999","unstructured":"Joris JL, Hamoir EE, Hartstein GM, Meurisse MR, Hubert BM, Charlier CJ, Lamy ML (1999) Hemodynamic changes and catecholamine release during laparoscopic adrenalectomy for pheochromocytoma. Anesth Analg 88:16\u201321","journal-title":"Anesth Analg"},{"key":"6777_CR9","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1016\/j.urology.2013.05.011","volume":"82","author":"G Wu","year":"2013","unstructured":"Wu G, Zhang B, Yu C, Gao L, Gao Y, Huang Y, Yu L, Zhang G, Yang L, Yuan J (2013) Effect of early adrenal vein ligation on blood pressure and catecholeamine fluctuation during laparoscopic adrenalectomy for pheochromocytoma. Urology 82:606\u2013611","journal-title":"Urology"},{"key":"6777_CR10","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1016\/j.surg.2015.09.016","volume":"159","author":"T Namekawa","year":"2016","unstructured":"Namekawa T, Utsumi T, Kawamura K, Kamiya N, Imamoto T, Takiguchi T, Hashimoto N, Tanaka T, Naya Y, Suzuki H, Ichikawa T (2016) Clinical predictors of prolonged postresection hypotension after laparoscopic adrenalectomy for pheochromocytoma. Surgery 159:763\u2013770","journal-title":"Surgery"},{"key":"6777_CR11","doi-asserted-by":"publisher","first-page":"678","DOI":"10.1210\/jc.2009-1051","volume":"95","author":"H Bruynzeel","year":"2010","unstructured":"Bruynzeel H, Feelders RA, Groenland TH, van den Meiracker AH, van Eijck CH, Lange JF, de Herder WW, Kazemier G (2010) Risk factors for hemodynamic instability during surgery for pheochromocytoma. J Clin Endocrinol Metab 95:678\u2013685","journal-title":"J Clin Endocrinol Metab"},{"key":"6777_CR12","doi-asserted-by":"publisher","first-page":"3865","DOI":"10.1245\/s10434-014-3847-7","volume":"21","author":"CM Kiernan","year":"2014","unstructured":"Kiernan CM, Du L, Chen X, Broome JT, Shi C, Peters MF, Solorzano CC (2014) Predictors of hemodynamic instability during surgery for pheochromocytoma. Ann Surg Oncol 21:3865\u20133871","journal-title":"Ann Surg Oncol"},{"key":"6777_CR13","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1097\/MPA.0b013e3181ebb4f0","volume":"39","author":"H Chen","year":"2010","unstructured":"Chen H, Sippel RS, O\u2019Dorisio MS, Vinik AI, Lloyd RV, Pacak K, North American Neuroendocrine Tumor S (2010) The North American Neuroendocrine Tumor Society consensus guideline for the diagnosis and management of neuroendocrine tumors: pheochromocytoma, paraganglioma, and medullary thyroid cancer. Pancreas 39:775\u2013783","journal-title":"Pancreas"},{"key":"6777_CR14","doi-asserted-by":"publisher","first-page":"3960","DOI":"10.1007\/s00464-013-3169-z","volume":"27","author":"D Stefanidis","year":"2013","unstructured":"Stefanidis D, Goldfarb M, Kercher KW, Hope WW, Richardson W, Fanelli RD, Society of G, Endoscopic S (2013) SAGES guidelines for minimally invasive treatment of adrenal pathology. Surg Endosc 27:3960\u20133980","journal-title":"Surg Endosc"},{"key":"6777_CR15","doi-asserted-by":"publisher","first-page":"998","DOI":"10.1007\/BF03018362","volume":"50","author":"J Mallat","year":"2003","unstructured":"Mallat J, Pironkov A, Destandau MS, Tavernier B (2003) Systolic pressure variation (Deltadown) can guide fluid therapy during pheochromocytoma surgery. Can J Anaesth 50:998\u20131003","journal-title":"Can J Anaesth"},{"key":"6777_CR16","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1007\/BF03019097","volume":"51","author":"T Iijima","year":"2004","unstructured":"Iijima T, Takagi T, Iwao Y (2004) An increased circulating blood volume does not prevent hypotension after pheochromocytoma resection. Can J Anaesth 51:212\u2013215","journal-title":"Can J Anaesth"},{"key":"6777_CR17","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1111\/cen.13142","volume":"85","author":"C Lentschener","year":"2016","unstructured":"Lentschener C, Gaujoux S, Baillard C, Dousset B (2016) Inappropriate adrenoreceptor blockade prior to phaeochromocytoma removal is perhaps a \u2018timely reappraisal\u2019? Clin Endocrinol 85:989\u2013990","journal-title":"Clin Endocrinol"},{"key":"6777_CR18","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1530\/EJE-11-0162","volume":"165","author":"C Lentschener","year":"2011","unstructured":"Lentschener C, Gaujoux S, Tesniere A, Dousset B (2011) Point of controversy: perioperative care of patients undergoing pheochromocytoma removal-time for a reappraisal? Eur J Endocrinol 165:365\u2013373","journal-title":"Eur J Endocrinol"},{"key":"6777_CR19","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1093\/bja\/aew392","volume":"118","author":"H Groeben","year":"2017","unstructured":"Groeben H, Nottebaum BJ, Alesina PF, Traut A, Neumann HP, Walz MK (2017) Perioperative alpha-receptor blockade in phaeochromocytoma surgery: an observational case series. Br J Anaesth 118:182\u2013189","journal-title":"Br J Anaesth"},{"key":"6777_CR20","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1053\/jcan.2002.124150","volume":"16","author":"MA Kinney","year":"2002","unstructured":"Kinney MA, Narr BJ, Warner MA (2002) Perioperative management of pheochromocytoma. J Cardiothorac Vasc Anesth 16:359\u2013369","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"6777_CR21","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1245\/s10434-016-5514-7","volume":"24","author":"RW Randle","year":"2017","unstructured":"Randle RW, Balentine CJ, Pitt SC, Schneider DF, Sippel RS (2017) Selective versus non-selective alpha-blockade prior to laparoscopic adrenalectomy for pheochromocytoma. Ann Surg Oncol 24:244\u2013250","journal-title":"Ann Surg Oncol"},{"key":"6777_CR22","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1111\/anae.13309","volume":"71","author":"R Gupta","year":"2016","unstructured":"Gupta R, Gan TJ (2016) Peri-operative fluid management to enhance recovery. Anaesthesia 71:40\u201345","journal-title":"Anaesthesia"},{"key":"6777_CR23","first-page":"1118","volume":"91","author":"MA Kinney","year":"2000","unstructured":"Kinney MA, Warner ME, vanHeerden JA, Horlocker TT, Young WF Jr, Schroeder DR, Maxson PM, Warner MA (2000) Perianesthetic risks and outcomes of pheochromocytoma and paraganglioma resection. Anesth Analg 91:1118\u20131123","journal-title":"Anesth Analg"},{"key":"6777_CR24","doi-asserted-by":"publisher","first-page":"1129","DOI":"10.1213\/00000539-198312000-00016","volume":"62","author":"FG Mihm","year":"1983","unstructured":"Mihm FG (1983) Pulmonary artery pressure monitoring in patients with pheochromocytoma. Anesth Analg 62:1129\u20131133","journal-title":"Anesth Analg"},{"key":"6777_CR25","doi-asserted-by":"publisher","first-page":"1114","DOI":"10.1111\/j.1399-6576.1998.tb05387.x","volume":"42","author":"P Colson","year":"1998","unstructured":"Colson P, Ryckwaert F, Ribstein J, Mann C, Dareau S (1998) Haemodynamic heterogeneity and treatment with the calcium channel blocker nicardipine during phaeochromocytoma surgery. Acta Anaesthesiol Scand 42:1114\u20131119","journal-title":"Acta Anaesthesiol Scand"},{"key":"6777_CR26","doi-asserted-by":"publisher","first-page":"820","DOI":"10.1097\/00000542-200210000-00012","volume":"97","author":"TJ Gan","year":"2002","unstructured":"Gan TJ, Soppitt A, Maroof M, El-Moalem H, Robertson KM, Moretti E, Dwane P, Glass PS (2002) Goal-directed intraoperative fluid administration reduces length of hospital stay after major surgery. Anesthesiology 97:820\u2013826","journal-title":"Anesthesiology"},{"key":"6777_CR27","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1093\/bja\/88.1.65","volume":"88","author":"R Venn","year":"2002","unstructured":"Venn R, Steele A, Richardson P, Poloniecki J, Grounds M, Newman P (2002) Randomized controlled trial to investigate influence of the fluid challenge on duration of hospital stay and perioperative morbidity in patients with hip fractures. Br J Anaesth 88:65\u201371","journal-title":"Br J Anaesth"},{"key":"6777_CR28","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1093\/bja\/aei223","volume":"95","author":"HG Wakeling","year":"2005","unstructured":"Wakeling HG, McFall MR, Jenkins CS, Woods WG, Miles WF, Barclay GR, Fleming SC (2005) Intraoperative oesophageal Doppler guided fluid management shortens postoperative hospital stay after major bowel surgery. Br J Anaesth 95:634\u2013642","journal-title":"Br J Anaesth"},{"key":"6777_CR29","doi-asserted-by":"publisher","first-page":"1349","DOI":"10.1007\/s00464-006-9106-7","volume":"21","author":"A Okrainec","year":"2007","unstructured":"Okrainec A, Bergman S, Demyttenaere S, Feldman LS, Nutting A, Carli F, Fried GM (2007) Validation of esophageal Doppler for noninvasive hemodynamic monitoring under pneumoperitoneum. Surg Endosc 21:1349\u20131353","journal-title":"Surg Endosc"},{"key":"6777_CR30","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1507\/endocrj.EJ13-0471","volume":"61","author":"Y Matsuda","year":"2014","unstructured":"Matsuda Y, Kawate H, Shimada S, Matsuzaki C, Nagata H, Adachi M, Ohnaka K, Nomura M, Takayanagi R (2014) Perioperative sequential monitoring of hemodynamic parameters in patients with pheochromocytoma using the non-invasive cardiac system (NICaS). Endocr J 61:571\u2013575","journal-title":"Endocr J"},{"key":"6777_CR31","first-page":"941","volume":"94","author":"MF Roizen","year":"1983","unstructured":"Roizen MF, Hunt TK, Beaupre PN, Kremer P, Firmin R, Chang CN, Alpert RA, Thomas CJ, Tyrrell JB, Cahalan MK (1983) The effect of alpha-adrenergic blockade on cardiac performance and tissue oxygen delivery during excision of pheochromocytoma. Surgery 94:941\u2013945","journal-title":"Surgery"},{"key":"6777_CR32","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1007\/s00464-015-4294-7","volume":"30","author":"L Brunaud","year":"2016","unstructured":"Brunaud L, Nguyen-Thi PL, Mirallie E, Raffaelli M, Vriens M, Theveniaud PE, Boutami M, Finnerty BM, Vorselaars WM, Rinkes IB, Bellantone R, Lombardi C, Fahey T 3rd, Zarnegar R, Bresler L (2016) Predictive factors for postoperative morbidity after laparoscopic adrenalectomy for pheochromocytoma: a multicenter retrospective analysis in 225 patients. Surg Endosc 30:1051\u20131059","journal-title":"Surg Endosc"},{"key":"6777_CR33","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1093\/bjaed\/mkv033","volume":"16","author":"D Connor","year":"2016","unstructured":"Connor D, Boumphrey S (2016) Perioperative care of phaeochromocytoma. BJA Educ 16:153\u2013158","journal-title":"BJA Educ"},{"key":"6777_CR34","unstructured":"James MFM (2010) Anaesthesia for patients with endocrine disease. Oxford University Press, Oxford"},{"key":"6777_CR35","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1097\/ALN.0b013e3181b437e0","volume":"111","author":"RA Dyer","year":"2009","unstructured":"Dyer RA, Reed AR, van Dyk D, Arcache MJ, Hodges O, Lombard CJ, Greenwood J, James MF (2009) Hemodynamic effects of ephedrine, phenylephrine, and the coadministration of phenylephrine with oxytocin during spinal anesthesia for elective cesarean delivery. Anesthesiology 111:753\u2013765","journal-title":"Anesthesiology"},{"key":"6777_CR36","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1097\/ALN.0b013e31818a401f","volume":"109","author":"E Langesaeter","year":"2008","unstructured":"Langesaeter E, Rosseland LA, Stubhaug A (2008) Continuous invasive blood pressure and cardiac output monitoring during cesarean delivery: a randomized, double-blind comparison of low-dose versus high-dose spinal anesthesia with intravenous phenylephrine or placebo infusion. Anesthesiology 109:856\u2013863","journal-title":"Anesthesiology"},{"key":"6777_CR37","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9780511722172","volume-title":"Pharmacology for anaesthesia and intensive care","author":"T Peck","year":"2008","unstructured":"Peck T (2008) Pharmacology for anaesthesia and intensive care, 3rd edn. Cambridge University Press, New York","edition":"3"},{"key":"6777_CR38","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1016\/j.bja.2017.12.030","volume":"120","author":"C Lentschener","year":"2018","unstructured":"Lentschener C, Gaujoux S, Mion G, Dousset B, Baillard C (2018) Most patients undergoing phaeochromocytoma removal could be safely discharged from the post-anaesthesia care unit to the ward after three hours monitoring. Br J Anaesth 120:879\u2013880","journal-title":"Br J Anaesth"},{"key":"6777_CR39","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1111\/cen.13252","volume":"86","author":"BG Challis","year":"2017","unstructured":"Challis BG, Casey RT, Simpson HL, Gurnell M (2017) Is there an optimal preoperative management strategy for phaeochromocytoma\/paraganglioma? Clin Endocrinol 86:163\u2013167","journal-title":"Clin Endocrinol"},{"key":"6777_CR40","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1093\/bja\/ael290","volume":"97","author":"MC Bellamy","year":"2006","unstructured":"Bellamy MC (2006) Wet, dry or something else? Br J Anaesth 97:755\u2013757","journal-title":"Br J Anaesth"},{"key":"6777_CR41","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1093\/bja\/aex076","volume":"118","author":"RTJ Wilson","year":"2017","unstructured":"Wilson RTJ, Minto G (2017) The great fluid debate: time for Flexit? Br J Anaesth 118:819\u2013822","journal-title":"Br J Anaesth"},{"key":"6777_CR42","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1016\/j.surg.2017.05.029","volume":"163","author":"W Vorselaars","year":"2018","unstructured":"Vorselaars W, Postma EL, Mirallie E, Thiery J, Lustgarten M, Pasternak JD, Bellantone R, Raffaelli M, Fahey T 3rd, Vriens MR, Bresler L, Brunaud L, Zarnegar R (2018) Hemodynamic instability during surgery for pheochromocytoma: comparing the transperitoneal and retroperitoneal approach in a multicenter analysis of 341 patients. Surgery 163:176\u2013182","journal-title":"Surgery"}],"container-title":["Surgical Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00464-019-06777-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00464-019-06777-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00464-019-06777-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,15]],"date-time":"2022-09-15T19:55:36Z","timestamp":1663271736000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00464-019-06777-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,11]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["6777"],"URL":"https:\/\/doi.org\/10.1007\/s00464-019-06777-z","relation":{},"ISSN":["0930-2794","1432-2218"],"issn-type":[{"value":"0930-2794","type":"print"},{"value":"1432-2218","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,11]]},"assertion":[{"value":"7 November 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 April 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 April 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"Drs. Martin B. Niederle, Edith Fleischmann, Barbara Kabon and Bruno Niederle have no conflicts of interest or financial ties to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}}]}}