{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:11:11Z","timestamp":1792678271360,"version":"4.5.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2019,7,10]],"date-time":"2019-07-10T00:00:00Z","timestamp":1562716800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,7,10]],"date-time":"2019-07-10T00:00:00Z","timestamp":1562716800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Surg Endosc"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1007\/s00464-019-06945-1","type":"journal-article","created":{"date-parts":[[2019,7,10]],"date-time":"2019-07-10T12:03:47Z","timestamp":1562760227000},"page":"1688-1695","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":67,"title":["Endoscopic submucosal dissection (ESD) versus transanal endoscopic microsurgery (TEM) for treatment of rectal tumors: a comparative systematic review and meta-analysis"],"prefix":"10.1007","volume":"34","author":[{"given":"Thomas R.","family":"McCarty","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad Najdat","family":"Bazarbashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly E.","family":"Hathorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6105-5270","authenticated-orcid":false,"given":"Christopher C.","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Aihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,7,10]]},"reference":[{"key":"6945_CR1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3322\/caac.21551","volume":"69","author":"RL Siegel","year":"2019","unstructured":"Siegel RL, Miller KD, Jemal A (2019) Cancer statistics, 2019. CA Cancer J Clin 69:7\u201334","journal-title":"CA Cancer J Clin"},{"key":"6945_CR2","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1055\/s-0032-1310015","volume":"44","author":"SU Park","year":"2012","unstructured":"Park SU, Min YW, Shin JU et al (2012) Endoscopic submucosal dissection or transanal endoscopic microsurgery for nonpolypoid rectal high grade dysplasia and submucosa-invading rectal cancer. Endoscopy 44:1031\u20131036","journal-title":"Endoscopy"},{"key":"6945_CR3","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.gie.2010.01.040","volume":"72","author":"HW Park","year":"2010","unstructured":"Park HW, Byeon JS, Park YS et al (2010) Endoscopic submucosal dissection for treatment of rectal carcinoid tumors. Gastrointest Endosc 72:143\u2013149","journal-title":"Gastrointest Endosc"},{"key":"6945_CR4","doi-asserted-by":"publisher","first-page":"202","DOI":"10.4174\/astr.2015.89.4.202","volume":"89","author":"MJ Nam","year":"2015","unstructured":"Nam MJ, Sohn DK, Hong CW et al (2015) Cost comparison between endoscopic submucosal dissection and transanal endoscopic microsurgery for the treatment of rectal tumors. Ann Surg Treat Res 89:202\u2013207","journal-title":"Ann Surg Treat Res"},{"key":"6945_CR5","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1055\/s-0031-1291448","volume":"44","author":"A Repici","year":"2012","unstructured":"Repici A, Hassan C, De Paula Pessoa D et al (2012) Efficacy and safety of endoscopic submucosal dissection for colorectal neoplasia: a systematic review. Endoscopy 44:137\u2013150","journal-title":"Endoscopy"},{"key":"6945_CR6","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1007\/s00464-009-0585-1","volume":"24","author":"M Guerrieri","year":"2010","unstructured":"Guerrieri M, Baldarelli M, de Sanctis A, Campagnacci R, Rimini M, Lezoche E (2010) Treatment of rectal adenomas by transanal endoscopic microsurgery: 15\u00a0years\u2019 experience. Surg Endosc 24:445\u2013449","journal-title":"Surg Endosc"},{"key":"6945_CR7","doi-asserted-by":"publisher","first-page":"45","DOI":"10.7812\/TPP\/11-120","volume":"16","author":"H Kunitake","year":"2012","unstructured":"Kunitake H, Abbas MA (2012) Transanal endoscopic microsurgery for rectal tumors: a review. Perm J 16:45\u201350","journal-title":"Perm J"},{"key":"6945_CR8","doi-asserted-by":"publisher","first-page":"1173","DOI":"10.1007\/s00464-013-3302-z","volume":"28","author":"FS Kawaguti","year":"2014","unstructured":"Kawaguti FS, Nahas CS, Marques CF et al (2014) Endoscopic submucosal dissection versus transanal endoscopic microsurgery for the treatment of early rectal cancer. Surg Endosc 28:1173\u20131179","journal-title":"Surg Endosc"},{"key":"6945_CR9","doi-asserted-by":"publisher","first-page":"115","DOI":"10.4103\/sjg.SJG_440_17","volume":"24","author":"Y Jung","year":"2018","unstructured":"Jung Y, Lee J, Cho JY et al (2018) Comparison of efficacy and safety between endoscopic submucosal dissection and transanal endoscopic microsurgery for the treatment of rectal tumor. Saudi J Gastroenterol 24:115\u2013121","journal-title":"Saudi J Gastroenterol"},{"key":"6945_CR10","doi-asserted-by":"publisher","first-page":"W65","DOI":"10.7326\/0003-4819-151-4-200908180-00136","volume":"151","author":"A Liberati","year":"2009","unstructured":"Liberati A, Altman DG, Tetzlaff J et al (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. Ann Intern Med 151:W65\u2013W94","journal-title":"Ann Intern Med"},{"key":"6945_CR11","doi-asserted-by":"publisher","first-page":"i4919","DOI":"10.1136\/bmj.i4919","volume":"355","author":"JA Sterne","year":"2016","unstructured":"Sterne JA, Hernan MA, Reeves BC et al (2016) ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ 355:i4919","journal-title":"BMJ"},{"key":"6945_CR12","unstructured":"Wells G, Shea B et al (2000) The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analysis. In: 3rd symposium on systematic reviews: beyond the basics; July 3\u20135; Oxford. \nhttp:\/\/www.ohri.ca\/programs\/clinical_epidemiology\/oxford.asp\n\n. Accessed 18 Dec 2018"},{"key":"6945_CR13","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","volume":"327","author":"JP Higgins","year":"2003","unstructured":"Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ 327:557\u2013560","journal-title":"BMJ"},{"key":"6945_CR14","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","volume":"315","author":"M Egger","year":"1997","unstructured":"Egger M, Davey Smith G, Schneider M, Minder C (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315:629\u2013634","journal-title":"BMJ"},{"key":"6945_CR15","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","volume":"7","author":"R DerSimonian","year":"1986","unstructured":"DerSimonian R, Laird N (1986) Meta-analysis in clinical trials. Control Clin Trials 7:177\u2013188","journal-title":"Control Clin Trials"},{"key":"6945_CR16","volume-title":"Kendall\u2019s advanced theory of statistics","author":"A Stuart","year":"1994","unstructured":"Stuart A, Ord JK (1994) Kendall\u2019s advanced theory of statistics, 6th edn. Edward Arnold, London","edition":"6"},{"key":"6945_CR17","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1272\/jnms.72.278","volume":"72","author":"H Suzuki","year":"2005","unstructured":"Suzuki H, Furukawa K, Kan H et al (2005) The role of transanal endoscopic microsurgery for rectal tumors. J Nippon Med Sch 72:278\u2013284","journal-title":"J Nippon Med Sch"},{"key":"6945_CR18","doi-asserted-by":"publisher","first-page":"6268","DOI":"10.3748\/wjg.v22.i27.6268","volume":"22","author":"S Tanaka","year":"2016","unstructured":"Tanaka S, Toyonaga T, Morita Y et al (2016) Feasibility and safety of endoscopic submucosal dissection for lower rectal tumors with hemorrhoids. World J Gastroenterol 22:6268\u20136275","journal-title":"World J Gastroenterol"},{"key":"6945_CR19","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1007\/s00464-013-3238-3","volume":"28","author":"A Arezzo","year":"2014","unstructured":"Arezzo A, Passera R, Saito Y et al (2014) Systematic review and meta-analysis of endoscopic submucosal dissection versus transanal endoscopic microsurgery for large noninvasive rectal lesions. Surg Endosc 28:427\u2013438","journal-title":"Surg Endosc"},{"key":"6945_CR20","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/j.giec.2013.11.005","volume":"24","author":"Y Saito","year":"2014","unstructured":"Saito Y, Sakamoto T, Nakajima T, Matsuda T (2014) Colorectal ESD: current indications and latest technical advances. Gastrointest Endosc Clin N Am 24:245\u2013255","journal-title":"Gastrointest Endosc Clin N Am"},{"key":"6945_CR21","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1038\/ajg.2009.547","volume":"105","author":"Y Takeuchi","year":"2010","unstructured":"Takeuchi Y, Uedo N, Ishihara R et al (2010) Efficacy of an endo-knife with a water-jet function (Flushknife) for endoscopic submucosal dissection of superficial colorectal neoplasms. Am J Gastroenterol 105:314\u2013322","journal-title":"Am J Gastroenterol"},{"key":"6945_CR22","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/j.gie.2008.10.064","volume":"70","author":"H Toyoizumi","year":"2009","unstructured":"Toyoizumi H, Kaise M, Arakawa H et al (2009) Ultrathin endoscopy versus high-resolution endoscopy for diagnosing superficial gastric neoplasia. Gastrointest Endosc 70:240\u2013245","journal-title":"Gastrointest Endosc"},{"key":"6945_CR23","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1111\/j.1463-1318.2006.01132.x","volume":"9","author":"S Maslekar","year":"2007","unstructured":"Maslekar S, Pillinger SH, Sharma A, Taylor A, Monson JR (2007) Cost analysis of transanal endoscopic microsurgery for rectal tumours. Colorectal Dis 9:229\u2013234","journal-title":"Colorectal Dis"},{"key":"6945_CR24","unstructured":"Higgins JP, Green S. Cochrane handbook for systematic reviews of interventions. Version 5.1.0. \nhttp:\/\/handbook-5-1.cochrane.org\n\n. Accessed 2 Dec 2018"},{"key":"6945_CR25","doi-asserted-by":"publisher","first-page":"3923","DOI":"10.1007\/s00464-011-1821-z","volume":"25","author":"SS Hon","year":"2011","unstructured":"Hon SS, Ng SS, Chiu PW et al (2011) Endoscopic submucosal dissection versus local excision for early rectal neoplasms: a comparative study. Surg Endosc 25:3923\u20133927","journal-title":"Surg Endosc"},{"key":"6945_CR26","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1055\/s-0034-1368593","volume":"140","author":"MH Hitzler","year":"2015","unstructured":"Hitzler MH, Heintz A (2015) Single centre study: results of transanal endoscopic microsurgery of rectal tumors since 2003 vs. results of endoscopic submucosal dissection reported in the literature. Zentralbl Chir 140:645\u2013650","journal-title":"Zentralbl Chir"}],"container-title":["Surgical Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00464-019-06945-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00464-019-06945-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00464-019-06945-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,8]],"date-time":"2020-07-08T19:08:00Z","timestamp":1594235280000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00464-019-06945-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,10]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["6945"],"URL":"https:\/\/doi.org\/10.1007\/s00464-019-06945-1","relation":{},"ISSN":["0930-2794","1432-2218"],"issn-type":[{"value":"0930-2794","type":"print"},{"value":"1432-2218","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,10]]},"assertion":[{"value":"26 February 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 June 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 July 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"Chris C. Thompson is a consultant for Boston Scientific, Olympus America, and Apollo Endosurgery. Hiroyuki Aihara is a consultant for Olympus America, Boston Scientific, and Fujifilm Medical Systems. Thomas R. McCarty, Ahmad Najdat Bazarbashi, and Kelly E. Hathorn have no conflicts to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}},{"value":"Institutional IRB approval and written consent was not required given the design of this systematic review and meta-analysis.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}