{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T13:36:14Z","timestamp":1760189774077,"version":"3.37.3"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T00:00:00Z","timestamp":1612483200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T00:00:00Z","timestamp":1612483200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Surg Endosc"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Radio-frequency ablation (RFA) for Barrett\u2019s oesophagus (BE)-related neoplasia is currently used after endoscopic resection of visible neoplasia. The HALO 360 balloon has been used to ablate long segment BE. The Barrx\u2122 360 Express RFA self-sizing catheter (\u2018RFA Express\u2019) may potentially allow quicker ablation times and improved treatment outcomes. The aim of this paper is to present real world data on the use of the 360 Express Device.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Centres in the UK and Ireland submitted cases where the RFA Express was used. The primary outcome was regression of BE at 3\u00a0months. Secondary outcomes were the rate of symptomatic stricture formation and resolution of intestinal metaplasia (CR-IM) and dysplasia (CR-D) at End of Treatment (EoT).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>11 centres submitted 123 consecutive patients. 112 had a follow up endoscopy. The median age was 67\u00a0years (IQR 62\u201375). 3 dosimetries were used. The mean reduction in Circumferential (C) length was 78%\u2009\u00b1\u200936 and mean reduction in Maximal length (M) was 55%\u2009\u00b1\u200936. 17 patients (15%) developed strictures requiring dilation. There was a higher rate of stricture formation when the 12\u00a0J energy was used (p\u2009&lt;\u20090.05). 47 patients had EoT biopsies, 40 (85%) had CR-D and 34(76%) had CR-IM.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>The RFA 360 Express catheter shows reduction in length of baseline BE at 3\u00a0months after index treatment, and eradication of intestinal metaplasia and dysplasia at 12\u00a0months similar to other studies with earlier devices. It appears that the symptomatic stricture rate is slightly higher than previous series with the HALO 360 catheter.<\/jats:p>\n                <jats:p>This study was performed as part of the HALO registry and has been approved by the Research Ethics Committee - MREC Number 08\/H0714\/27 Local project reference 08\/0104 Project ID 15,033 IRAS Number 54678 EudraCT 2009-015980-1. Registered on ISRCTN as below: ISRCTN93069556. https:\/\/doi.org\/10.1186\/ISRCTN93069556<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00464-021-08325-0","type":"journal-article","created":{"date-parts":[[2021,2,8]],"date-time":"2021-02-08T15:11:31Z","timestamp":1612797091000},"page":"598-606","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Radiofrequency ablation for Barrett\u2019s oesophagus related neoplasia with the 360 Express catheter: initial experience from the United Kingdom and Ireland\u2014preliminary results"],"prefix":"10.1007","volume":"36","clinical-trial-number":[{"clinical-trial-number":"isrctn93069556","registry":"10.18810\/isrctn"}],"author":[{"given":"Cormac G.","family":"Magee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Graham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles","family":"Gordon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason","family":"Dunn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian","family":"Penman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Willert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Howard","family":"Smart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacobo","family":"Ortiz-Fernandez-Sordo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krish","family":"Ragunath","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Everson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Durayd","family":"Alzoubaidi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Banks","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle","family":"Morris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarmed","family":"Sami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan J.","family":"Morris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pradeep","family":"Bhandari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravi","family":"Narayanasamy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimiliano","family":"Di Pietro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurence B.","family":"Lovat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2063-1857","authenticated-orcid":false,"given":"Rehan","family":"Haidry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,2,5]]},"reference":[{"issue":"9","key":"8325_CR1","doi-asserted-by":"publisher","first-page":"1200","DOI":"10.1136\/gut.2007.142539","volume":"57","author":"O Pech","year":"2008","unstructured":"Pech O, Behrens A, May A et al (2008) Long term results and risk factor analysis for recurrence after curative endoscopic therapy in 349 patients with high grade intraepithelial neoplasia and mucosal adenocarcinoma in Barrett\u2019s oesophagus. 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Author Allan J Morris has declared grants and personal fees from companies unrelated to this study. Authors Cormac Magee, David Graham, Charles Gordon, Jason Dunn, Ian Penman, Robert Willert, Howard Smart, Jacobo Ortiz-Fernandez-Sordo, Krish Ragunath, Martin Everson, Durayd Alzoubaidi, Matthew Banks, Danielle Morris, Sarmed Sami, Allan J Morris, Pradeep Bhandari, Ravi Narayanasamy, Massimiliano Di Pietro, Laurence B Lovat, Rehan Haidry have no conflicts of interest or financial ties to disclose. There was no external funding provided for this study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}}]}}