{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T12:01:37Z","timestamp":1791633697441,"version":"4.3.4"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Surg Endosc"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Surgery is the gold standard for the treatment of malignant tumors of the rectum. Intestinal anastomotic leakage remains a serious complication of colorectal surgery. The efficacy and safety of transrectal endoscopic drainage by vacuum therapy in patients with intestinal anastomotic leakage after surgical treatment of middle and distal rectal tumors were assessed.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Prospective analysis of treatment outcomes among patients undergoing surgery for middle and distal rectal tumors at the Department of General, Gastroenterological, and Oncological Surgery of the Ludwik Rydygier Collegium Medicum in Bydgoszcz and Nicolaus Copernicus University in Torun from 2016 to 2019 was conducted.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Seventy-nine patients with middle and distal rectal tumors underwent laparoscopic resection. Intestinal anastomotic leak was identified in 18 (22.79%) patients [all men, mean age 61.39 (43\u201386) years] during the postoperative period. Primary protective ileostomy was performed in 8\/18 (44.44%) patients.\u00a0All 18 patients were treated with endoluminal vacuum therapy via transrectal endoscopic drainage. The mean time from surgery to the diagnosis of leakage and initiation of endoscopic treatment was 16 (3\u2013728) days. The mean number of endoscopic procedures per patient was 6 (1\u201311). The mean duration of endoscopic treatment was 22 (4\u201343) days. Complications of endotherapy occurred in 2\/18 (11.11%) patients treated endoscopically for bleeding from the abscess cavity. Success of endoluminal vacuum therapy was achieved in 17\/18 (94.44%) patients. Moreover, 5\/18 (27.78%) patients required ileostomy during the endoscopic treatment. The mean follow-up period was 368 (118\u2013724) days. Long-term success of transrectal endoscopic drainage using vacuum-assisted therapy was achieved in 15\/18 (83.33%) patients.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Endoscopic rectal drainage using vacuum-assisted therapy is an effective and safe minimally invasive treatment in patients with intestinal anastomotic leaks following resection procedures within the middle and distal rectum.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00464-021-08359-4","type":"journal-article","created":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T17:03:16Z","timestamp":1614618196000},"page":"959-967","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Transrectal endoscopic drainage with vacuum-assisted therapy in patients with anastomotic leaks following rectal cancer resection"],"prefix":"10.1007","volume":"36","author":[{"given":"Mateusz","family":"Jagielski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacek","family":"Pi\u0105tkowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grzegorz","family":"Jarczyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Jackowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,3,1]]},"reference":[{"key":"8359_CR1","doi-asserted-by":"publisher","first-page":"1.e1","DOI":"10.1016\/j.ejca.2013.06.048","volume":"50","author":"CJ van de Velde","year":"2014","unstructured":"van de Velde CJ, Boelens PG, Borras JM, Coebergh JW, Cervantes A, Blomqvist L, Beets-Tan RG, van den Broek CB, Brown G, Van Cutsem E, Espin E, Haustermans K, Glimelius B, Iversen LH, van Krieken JH, Marijnen CA, Henning G, Gore-Booth J, Meldolesi E, Mroczkowski P, Nagtegaal I, Naredi P, Ortiz H, P\u00e5hlman L, Quirke P, R\u00f6del C, Roth A, Rutten H, Schmoll HJ, Smith JJ, Tanis PJ, Taylor C, Wibe A, Wiggers T, Gambacorta MA, Aristei C, Valentini V (2014) EURECCA colorectal: multidisciplinary management: European consensus conference colon & rectum. Eur J Cancer 50:1.e1-1.e34","journal-title":"Eur J Cancer"},{"key":"8359_CR2","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/j.clcc.2015.06.002","volume":"14","author":"M Lee","year":"2015","unstructured":"Lee M, Gibbs P, Wong R (2015) Multidisciplinary Management of Locally Advanced Rectal Cancer-an Evolving Landscape? Clin Colorectal Cancer 14:251\u2013261","journal-title":"Clin Colorectal Cancer"},{"key":"8359_CR3","doi-asserted-by":"publisher","first-page":"2537","DOI":"10.1016\/S0140-6736(18)31078-X","volume":"391","author":"van der Valk MJM, Hilling DE, Bastiaannet E, Meershoek-Klein Kranenbarg E, Beets GL, Figueiredo NL, Habr-Gama A, Perez RO, Renehan AG, van de Velde CJH, IWWD Consortium","year":"2018","unstructured":"van der Valk MJM, Hilling DE, Bastiaannet E, Meershoek-Klein Kranenbarg E, Beets GL, Figueiredo NL, Habr-Gama A, Perez RO, Renehan AG, van de Velde CJH, IWWD Consortium (2018) Long-term outcomes of clinical complete responders after neoadjuvant treatment for rectal cancer in the International Watch & Wait Database (IWWD): an international multicentre registry study. Lancet 391:2537\u20132545","journal-title":"Lancet"},{"key":"8359_CR4","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1007\/s10151-017-1662-4","volume":"21","author":"M P\u0119dziwiatr","year":"2017","unstructured":"P\u0119dziwiatr M, Ma\u0142czak P, Mizera M, Witowski J, Torbicz G, Major P, Pisarska M, Wysocki M, Budzy\u0144ski A (2017) There is no difference in outcome between laparoscopic and open surgery for rectal cancer: a systematic review and meta-analysis on short- and long-term oncologic outcomes. Tech Coloproctol 21:595\u2013604","journal-title":"Tech Coloproctol"},{"key":"8359_CR5","doi-asserted-by":"publisher","first-page":"1418","DOI":"10.1007\/s11605-018-3738-5","volume":"22","author":"H Nienh\u00fcser","year":"2018","unstructured":"Nienh\u00fcser H, Heger P, Schmitz R, Kulu Y, Diener MK, Klose J, Schneider M, M\u00fcller-Stich BP, Ulrich A, B\u00fcchler MW, Mihaljevic AL, Schmidt T (2018) Short- and long-term oncological outcome after rectal cancer surgery: a systematic review and meta-analyzis comparing open versus laparoscopic rectal cancer surgery. J Gastrointest Surg 22:1418\u20131433","journal-title":"J Gastrointest Surg"},{"key":"8359_CR6","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1097\/SLA.0000000000003002","volume":"269","author":"ME Branda","year":"2019","unstructured":"Branda ME, Sargent DJ, Boller AM, George VV, Abbas MA, Peters WR, Maun DC, Chang GJ, Herline A, Fichera A, Mutch MG, Wexner SD, Whiteford MH, Marks J, Birnbaum E, Margolin DA, Larson DW, Marcello PW, Posner MC, Read TE, Monson JRT, Wren SM, Pisters PWT (2019) Nelson H (2019) Disease-free survival and local recurrence for laparoscopic resection compared with open resection of stage II to III rectal cancer: follow-up results of the ACOSOG Z6051 randomized controlled trial. Ann Surg 269:589\u2013595","journal-title":"Ann Surg"},{"key":"8359_CR7","doi-asserted-by":"crossref","unstructured":"Pi\u0105tkowski J, Jackowski M, Nowak M, Szeliga J (2019) TaTME: 2 Years of Experience of a Single Center Surg Laparosc Endosc Percutan Tech 29:64\u201368.","DOI":"10.1097\/SLE.0000000000000599"},{"key":"8359_CR8","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1046\/j.1365-2168.1998.00615.x","volume":"85","author":"E Rullier","year":"1999","unstructured":"Rullier E, Laurent C, Garrelon JL, Michel P, Saric J, Parneix M (1999) Risk factors for anastomotic leakage after resection of rectal cancer. Br J Surg 85:355\u2013358","journal-title":"Br J Surg"},{"key":"8359_CR9","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1016\/j.giec.2012.10.002","volume":"23","author":"N Kumar","year":"2013","unstructured":"Kumar N, Thompson CC (2013) Endoscopic therapy for postoperative leaks and fistulae. Gastrointest Endosc Clin N Am 23:123\u2013136","journal-title":"Gastrointest Endosc Clin N Am"},{"key":"8359_CR10","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/j.jamcollsurg.2008.10.015","volume":"208","author":"TP Kingham","year":"2009","unstructured":"Kingham TP, Pachter HL (2009) Colonic anastomotic leak: risk factors, diagnosis and treatment. J Am Coll Surg 208:269\u2013278","journal-title":"J Am Coll Surg"},{"key":"8359_CR11","unstructured":"Keighley MRB, Williams NS (1993) Surgery of the anus, rectum and colon. 1st Edition, Elsevier."},{"key":"8359_CR12","doi-asserted-by":"publisher","first-page":"1818","DOI":"10.1007\/s00464-007-9706-x","volume":"22","author":"R Weidenhagen","year":"2007","unstructured":"Weidenhagen R, Gruetzner KU, Wiecken T, Spelsberg F, Jauch KW (2007) Endoscopic vacuum-assisted closure of anastomotic leakage following anterior resection of the rectum: a new method. Surg Endosc 22:1818\u20131825","journal-title":"Surg Endosc"},{"key":"8359_CR13","doi-asserted-by":"publisher","first-page":"708","DOI":"10.1016\/j.gie.2007.10.064","volume":"67","author":"J Wedemeyer","year":"2008","unstructured":"Wedemeyer J, Schneider A, Manns MP, Jackobs S (2008) Endoscopic vacuum-assisted closure of upper intestinal anastomotic leaks. Gastrointest Endosc 67:708\u2013711","journal-title":"Gastrointest Endosc"},{"key":"8359_CR14","doi-asserted-by":"publisher","first-page":"1379","DOI":"10.1007\/s00464-008-0186-4","volume":"23","author":"PJ van Koperen","year":"2008","unstructured":"van Koperen PJ, van Berge Henegouwen MI, Rosman C, Bakker CM, Heres P, Slors JFM, Bemelman WA (2008) The dutch multicenter experience of the endo-sponge treatment for anastomotic leakage after colorectal burgery. Surg Endosc 23:1379\u20131383","journal-title":"Surg Endosc"},{"key":"8359_CR15","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1016\/j.bjps.2011.06.001","volume":"64","author":"H Birke-Sorensen","year":"2011","unstructured":"Birke-Sorensen H, Malmsjo M, Rome P, Hudson D, Krug E, Berg L, Bruhin A, Caravaggi C, Chariker M, Depoorter M, Dowsett C, Dunn R, Duteille F, Ferreira F, Mart\u00ednez JF, Grudzien G, Ichioka S, Ingemansson R, Jeffery S, Lee C, Vig S, Runkel N, Martin R, Smith J (2011) Evidence-based recommendations for negative pressure wound therapy: Treatment variables (pressure levels, wound filler and contact layer) \u2013 steps towards an international consensus. J Plast Reconstr Aesth Surg 64:S1\u2013S16","journal-title":"J Plast Reconstr Aesth Surg"},{"key":"8359_CR16","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1016\/S0020-1383(11)00041-6","volume":"42","author":"E Krug","year":"2011","unstructured":"Krug E, Berg L, Lee C, Hudson D, Birke-Sorensen H, Depoorter M, Dunn R, Jeffery S, Duteille F, Bruhin A, Caravaggi C, Chariker M, Dowsett C, Ferreira F, Mart\u00ednez JF, Grudzien G, Ichioka S, Ingemansson R, Malmsjo M, Rome P, Vig S, Runkel N, Martin R, Smith J (2011) Evidence-based recommendations for the use of negative pressure wound therapy in traumatic wounds and reconstructive surgery: Steps towards an international consensus. Injury 42:S1\u2013S12","journal-title":"Injury"},{"key":"8359_CR17","doi-asserted-by":"crossref","unstructured":"Riss S (2010) Recurrent abscess after primary successful endo-sponge treatment of anastomotic leakage following rectal surgery. World J Gastroenterol, vol. 16, no. 36, p. 4570, 2010.","DOI":"10.3748\/wjg.v16.i36.4570"},{"key":"8359_CR18","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1007\/s11605-015-3017-7","volume":"20","author":"F Kuehn","year":"2016","unstructured":"Kuehn F, Janisch F, Schwandner F, Alsfasser G, Schiffmann L, Gock M, Klar E (2016) Endoscopic vacuum therapy in colorectal surgery. J Gastrointest Surg 20:328\u2013334","journal-title":"J Gastrointest Surg"},{"key":"8359_CR19","doi-asserted-by":"publisher","first-page":"737","DOI":"10.6061\/clinics\/2017(12)04","volume":"72","author":"F Kamamoto","year":"2017","unstructured":"Kamamoto F, Lima ALM, Rezende MR, Mattar-Junior R, Leonhardt MC, Kojima KE, Santos CCD (2017) A new low-cost negative-pressure wound therapy versus a commercially available therapy device widely used to treat complex traumatic injuries: a prospective, randomized, non-inferiority trial. Clinics (Sao Paulo) 72:737\u2013742","journal-title":"Clinics (Sao Paulo)"},{"key":"8359_CR20","doi-asserted-by":"publisher","first-page":"560","DOI":"10.5114\/wiitm.2020.93204","volume":"15","author":"A Bobkiewicz","year":"2020","unstructured":"Bobkiewicz A, Krokowicz L, Banasiewicz T, Borejsza-Wysocki M (2020) Endoscopic vacuum therapy with instillation (iEVT) \u2013 a novel endoscopic concept for colorectal anastomotic leak and perianal complications. Videosurgery and Other Miniinvasive Techniques 15:560\u2013566","journal-title":"Videosurgery and Other Miniinvasive Techniques"}],"container-title":["Surgical Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00464-021-08359-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00464-021-08359-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00464-021-08359-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,13]],"date-time":"2022-01-13T16:12:11Z","timestamp":1642090331000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00464-021-08359-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,1]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["8359"],"URL":"https:\/\/doi.org\/10.1007\/s00464-021-08359-4","relation":{},"ISSN":["0930-2794","1432-2218"],"issn-type":[{"value":"0930-2794","type":"print"},{"value":"1432-2218","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,1]]},"assertion":[{"value":"8 July 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 February 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 March 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"Mateusz Jagielski, Jacek Pi\u0105tkowski, Grzegorz Jarczyk, and Marek Jackowski have no conflicts of interest or financial ties to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}}]}}