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This study aims to evaluate the causes and types of reintervention following index admission LC with or without CBDE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospectively maintained database of LC and CBDE performed by a single surgeon was analysed. Preoperative factors, difficulty grading and perioperative complications requiring reintervention and readmissions were examined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Reinterventions were required in 112 of 5740 patients (2.0%), 89 (1.6%) being subsequent to complications. The reintervention cohort had a median age of 64\u00a0years, were more likely to be females (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0023) and to be emergency admissions (67.9%,<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.00001) with obstructive jaundice (35.7%,<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.00001). 46.4% of the reintervention cohort had a LC operative difficulty grade IV or V and 65.2% underwent a CBDE. Open conversion was predictive of the potential for reintervention (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.00001). The most common single cause of reintervention was retained stones (0.5%) requiring ERCP followed by bile leakage (0.3%) requiring percutaneous drainage, ERCP and relaparoscopy. Relaparoscopy was necessary in 17 patients and open surgery in 13, 6 of whom not resulting from complications. There were 5 deaths.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This large series had a low incidence of reinterventions resulting from complications in spite of a high workload of index admission surgery for biliary emergencies and bile duct stones. Surgical or endoscopic reinterventions following LC alone occurred in only 0.8%. The most common form of reintervention was ERCP for retained CBD stones. This important outcome parameter of laparoscopic biliary surgery can be optimised through early diagnosis and timely reintervention for complications.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00464-021-08568-x","type":"journal-article","created":{"date-parts":[[2021,6,2]],"date-time":"2021-06-02T14:23:30Z","timestamp":1622643810000},"page":"2809-2817","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Reinterventions following laparoscopic cholecystectomy and bile duct exploration. A review of prospective data from 5740 patients"],"prefix":"10.1007","volume":"36","author":[{"given":"Hwei Jene","family":"Ng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7878-7024","authenticated-orcid":false,"given":"Ahmad H. 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Ng and Nassar have no conflict of interest or financial ties to disclose. Dr A Nassar performed or personally supervised all operations included in this series.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}}]}}