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Outcomes were collected up to 36\u00a0months. The primary outcome of the present study was cumulative morbidity and mortality. Secondary outcomes included reoperations (including stoma reversals), stoma rates, and sigmoidectomy rates in the lavage group.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Long-term follow-up was recorded in 77 of the 88 originally included patients, 39 were randomised to sigmoidectomy (51%) and 38 to laparoscopic lavage (49%). After 36\u00a0months, overall cumulative morbidity (sigmoidectomy 28\/39 (72%) versus lavage 32\/38 (84%), <jats:italic>p<\/jats:italic>\u2009=\u20090\u00b7272) and mortality (sigmoidectomy 7\/39 (18%) versus lavage 6\/38 (16%), <jats:italic>p<\/jats:italic>\u2009=\u20091\u00b7000) did not differ. The number of patients who underwent a reoperation was significantly lower for lavage compared to sigmoidectomy (sigmoidectomy 27\/39 (69%) versus lavage 17\/38 (45%), <jats:italic>p<\/jats:italic>\u2009=\u20090\u00b7039). After 36\u00a0months, patients alive with stoma in situ was lower in the lavage group (proportion calculated from the Kaplan\u2013Meier life table, sigmoidectomy 17% vs lavage 11%, log-rank <jats:italic>p<\/jats:italic>\u2009=\u20090\u00b70268). Eventually, 17 of 38 (45%) patients allocated to lavage underwent sigmoidectomy.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Long-term outcomes showed that laparoscopic lavage was associated with less patients who underwent reoperations and lower stoma rates in patients alive after 36\u00a0months compared to sigmoidectomy. No differences were found in terms of cumulative morbidity or mortality. Patient selection should be improved to reduce risk for short-term complications after which lavage could still be a valuable treatment option.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Graphical abstract<\/jats:title>\n                \n              <\/jats:sec>","DOI":"10.1007\/s00464-022-09326-3","type":"journal-article","created":{"date-parts":[[2022,5,23]],"date-time":"2022-05-23T17:13:58Z","timestamp":1653326038000},"page":"7764-7774","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Laparoscopic peritoneal lavage versus sigmoidectomy for perforated diverticulitis with purulent peritonitis: three-year follow-up of the randomised LOLA trial"],"prefix":"10.1007","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3445-2091","authenticated-orcid":false,"given":"Vincent T.","family":"Hoek","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8995-4166","authenticated-orcid":false,"given":"Pim P.","family":"Edomskis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pieter W.","family":"Stark","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel P. 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