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However, none of these diagnostic tools evaluate the pylorus itself. Our study demonstrates the successful measurement of pyloric distensibility in patients with DGCE after esophagectomy and in those without it.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods and procedures<\/jats:title>\n                <jats:p>Between May 2021 and October 2021, we performed a retrospective single-centre study of all patients who had an oncological Ivor-Lewis esophagectomy and underwent our post-surgery follow-up programme with surveillance endoscopies and computed tomography scans. EndoFlip\u2122 was used to perform measurements of the pylorus under endoscopic control, and distensibility was measured at 40\u00a0ml, 45\u00a0ml and 50\u00a0ml balloon filling.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>We included 70 patients, and EndoFlip\u2122 measurement was feasible in all patients. Successful application of EndoFlip\u2122 was achieved in all interventions (<jats:italic>n<\/jats:italic>\u2009=\u200970, 100%). 51 patients showed a normal postoperative course, whereas 19 patients suffered from DGCE. Distensibility proved to be smaller in patients with symptoms of DGCE compared to asymptomatic patients. For 40\u00a0ml, 45\u00a0ml and 50\u00a0ml, the mean distensibility was 6.4 vs 10.1, 5.7 vs 7.9 and 4.5 vs 6.3 mm<jats:sup>2<\/jats:sup>\/mmHg. The differences were significant for all three balloon fillings. No severe EndoFlip\u2122 treatment-related adverse events occurred.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Measurement with EndoFlip\u2122 is a safe and technically feasible endoscopic option for measuring the distensibility of the pylorus. Our study shows that the distensibility in asymptomatic patients after esophagectomy is significantly higher than that in patients suffering from DGCE. However, more studies need to be conducted to demonstrate the general use of EndoFlip\u2122 measurement of the pylorus after esophagectomy.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00464-022-09714-9","type":"journal-article","created":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T18:41:37Z","timestamp":1669920097000},"page":"5635-5643","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Assessment of pyloric sphincter physiology after Ivor-Lewis esophagectomy using an endoluminal functional lumen imaging probe"],"prefix":"10.1007","volume":"37","author":[{"given":"Stefanie","family":"Brunner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Lorenz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Dratsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenz","family":"Schr\u00f6der","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich","family":"Toex","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Babic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans Friedrich","family":"Fuchs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christiane Josephine","family":"Bruns","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Goeser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8923-6428","authenticated-orcid":false,"given":"Seung-Hun","family":"Chon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,12,1]]},"reference":[{"issue":"9","key":"9714_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/nmo.13980","volume":"32","author":"C Desprez","year":"2020","unstructured":"Desprez C, Roman S, Leroi AM, Gourcerol G (2020) The use of impedance planimetry (Endoscopic Functional Lumen Imaging Probe, EndoFLIP\u00ae) in the gastrointestinal tract: a systematic review. 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