{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T18:52:07Z","timestamp":1793472727527,"version":"4.5.0"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T00:00:00Z","timestamp":1674604800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T00:00:00Z","timestamp":1674604800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Capital\u2019s Funds for Health Improvement and Research","award":["(2020-2-1112)"],"award-info":[{"award-number":["(2020-2-1112)"]}]},{"name":"Research Foundation of Beijing Friendship Hospital, Capital Medical University","award":["yyqdkt2018-11"],"award-info":[{"award-number":["yyqdkt2018-11"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Surg Endosc"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Introduction<\/jats:title>\n                <jats:p>This study compares the perioperative results, aesthetic outcome and oncologic safety of single-port insufflation endoscopic nipple-sparing subcutaneous mastectomy combined with immediate reconstruction using prosthesis implantation (SIE-NSM-IRPI) with those of conventional open-nipple and areola-sparing subcutaneous mastectomy combined with immediate reconstruction using prosthesis implantation (C-NSM-IRPI).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>In this retrospective cohort study, 64 early-stage breast cancer patients were divided into SIE-NSM-IRPI (n\u2009=\u200938) and C-NSM-IRPI (n\u2009=\u200926) groups. Perioperative results (operation time, intraoperative blood loss, incision length, drainage duration, and recent complications) were then compared between the two groups. Differences in satisfaction with the breasts, psychosocial well-being, physical well-being (chest) and sexual well-being were analyzed according to the BREAST-Q scale, and survival outcomes were also compared.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The median follow-up time was 51.5\u00a0months. The incision length of SIE-NSM-IRPI was shorter than that of C-NSM-IRPI (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). SIE-NSM-IRPI achieved the same detection rate and median number of sentinel lymph nodes as C-NSM-IRPI (3.00vs. 4.00, <jats:italic>P<\/jats:italic>\u2009=\u20090.780). The incidence of prosthesis removal due to infection or prosthesis exposure in the SIE-NSM-IRPI group was lower than that in the C-NSM-IRPI group (<jats:italic>P<\/jats:italic>\u2009=\u20090.015). Satisfaction with breasts (82.00vs.59.00, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), psychosocial well-being (93.00vs.77.00, <jats:italic>P<\/jats:italic>\u2009=\u20090.001) and physical well-being (chest) (89.00vs.82.00, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) scores were higher in the SIE-NSM-IRPI group. There were no significant differences between the two groups in disease-free survival (hazard ratio\u2009=\u20090.829, 95% confidence interval\u2009=\u20090.182\u20133.779) and overall survival (hazard ratio\u2009=\u20091.919, 95% confidence interval\u2009=\u20090.169\u201321.842).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>In this selected cohort of patients with early breast cancer, SIE-NSM-IRPI was comparable to C-NSM-IRPI, considering oncologic safety and detection of sentinel lymph nodes. It had a lower incidence of prosthesis removal, shorter incision length, and was associated with better patient satisfaction with the breasts. More random clinical trials of this novel approach in a larger cohort of Chinese patients with an extended follow-up period are needed in the future.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00464-023-09862-6","type":"journal-article","created":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T16:02:53Z","timestamp":1674662573000},"page":"3842-3851","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Single-port nipple-sparing subcutaneous mastectomy with immediate prosthetic breast reconstruction for breast cancer"],"prefix":"10.1007","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8367-1146","authenticated-orcid":false,"given":"Zi-Han","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7115-5972","authenticated-orcid":false,"given":"Guo-Xuan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9700-7871","authenticated-orcid":false,"given":"Wei-Hua","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9791-8093","authenticated-orcid":false,"given":"Shan-Shan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2177-2283","authenticated-orcid":false,"given":"Fang","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo-qian","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1247-7239","authenticated-orcid":false,"given":"Ya-qian","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhong-tao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7969-1056","authenticated-orcid":false,"given":"Xiang","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,1,25]]},"reference":[{"issue":"1","key":"9862_CR1","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3322\/caac.21708","volume":"72","author":"RL Siegel","year":"2022","unstructured":"Siegel RL et al (2022) Cancer statistics, 2022. 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Zi-Han Wang, Guo-Xuan Gao, Wei-Hua Liu, Shan-Shan Wu, Fang Xie, Wei Xu, Guo-qian Ding, Ya-qian Xu, Zhong-tao Zhang and Xiang Qu have no conflicts of interest or financial ties to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosure"}},{"value":"All surgical procedures and details of informed consent were approved by the ethics committee of Beijing Friendship Hospital affiliated with Capital Medical University, Beijing, China (2019-P2-052\u201302).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}