{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T03:08:39Z","timestamp":1789096119602,"version":"build-2803163510"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T00:00:00Z","timestamp":1686873600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T00:00:00Z","timestamp":1686873600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Surg Endosc"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Introduction<\/jats:title>\n                <jats:p>The impact of delayed gastric emptying (DGE) on the outcome of anti-reflux surgery (ARS) is controversial. There is concern that poor gastric emptying diminishes outcomes. Magnetic sphincter augmentation (MSA) may have a comparatively mild impact on gastric physiology, but the relationship between DGE and MSA outcomes is unknown. This study aims to evaluate the relationship between objective DGE and MSA outcomes over time.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Patients who completed gastric emptying scintigraphy (GES) prior to MSA between 2013 and 2021 were included. DGE was defined as a 4 h retention\u2009&gt;\u200910% or half emptying time\u2009&gt;\u200990\u00a0min on GES. Outcomes were compared between DGE and normal gastric emptying (NGE) groups at 6 months, 1 and 2 years. Sub-analysis of patients with severe (&gt;\u200935%) DGE and correlation analysis between 4-h retention and symptom and acid-normalization were performed.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The study population consisted of 26 (19.8%) patients with DGE and 105 with NGE. DGE was associated with more 90-days readmissions (18.5 vs 2.9%, <jats:italic>p<\/jats:italic>\u2009=\u20090.009).<\/jats:p>\n                <jats:p>At 6 months patients with DGE had higher median (IQR) GERD-HRQL total [17.0(10\u201329) vs 5.5(3\u201316), <jats:italic>p<\/jats:italic>\u2009=\u20090.0013], heartburn [1(1\u20133) vs 0(0\u20131), <jats:italic>p<\/jats:italic>\u2009=\u20090.0010) and gas-bloat [4(2\u20135) vs 2(1\u20133), <jats:italic>p<\/jats:italic>\u2009=\u20090.033] scores.<\/jats:p>\n                <jats:p>Outcomes at 1 and 2 years follow-up were comparable (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05). From 6\u00a0months to 1-year the gas-bloat score decreased from 4(2\u20135<jats:underline>)<\/jats:underline> to 3(1\u20133), <jats:italic>p<\/jats:italic>\u2009=\u20090.041. Total and heartburn scores decreased, but not significantly.<\/jats:p>\n                <jats:p>Severe DGE (<jats:italic>n<\/jats:italic>\u2009=\u20094) patients had lower antiacid medication freedom at 6\u00a0months (75 vs 87%, <jats:italic>p<\/jats:italic>\u2009=\u20090.014) and 1-year (50 vs 92%, <jats:italic>p<\/jats:italic>\u2009=\u20090.046). There were non-significant trends for higher GERD-HRQL scores, dissatisfaction, and removal rates in severe DGE at 6\u00a0months and 1-year.<\/jats:p>\n                <jats:p>There was a weak correlation between 4-h retention and 6-month GERD-HRQL total score [<jats:italic>R<\/jats:italic>\u2009=\u20090.253, 95%CI (0.09\u20130.41), <jats:italic>p<\/jats:italic>\u2009=\u20090.039], but not acid-normalization (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Outcomes after MSA are diminished early on in patients with mild-to-moderate DGE, but comparable by 1 year and durable at 2 years. Severe DGE outcomes may be suboptimal.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Graphical abstract<\/jats:title>\n                \n              <\/jats:sec>","DOI":"10.1007\/s00464-023-10190-y","type":"journal-article","created":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T17:01:50Z","timestamp":1686934910000},"page":"7144-7152","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["The impact of delayed gastric emptying as measured by gastric emptying scintigraphy on the outcome of magnetic sphincter augmentation"],"prefix":"10.1007","volume":"37","author":[{"given":"Sven E.","family":"Eriksson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inanc S.","family":"Sarici","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinxin","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blair A.","family":"Jobe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8113-9164","authenticated-orcid":false,"given":"Shahin","family":"Ayazi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,6,16]]},"reference":[{"key":"10190_CR1","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1007\/s00268-006-0723-z","volume":"31","author":"S Masqusi","year":"2007","unstructured":"Masqusi S, Velanovich V (2007) Pyloroplasty with fundoplication in the treatment of combined gastroesophageal reflux disease and bloating. 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Shahin Ayazi and Blair Jobe are on the scientific advisory board of Johnson and Johnson and receive consulting fee. Drs. Sven Eriksson, Ping Zheng, Inanc Sarici and Ms. Xinxin Shen have no conflicts of interest or financial disclosures.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}}]}}