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Endoscopic retrograde cholangiopancreatography (ERCP) is the mainstay of management for removal of CBDS, as cholecystectomy for the prevention of recurrent biliary event (RBE). RBE occurs in up to 47% if cholecystectomy is not done. The goal of this study was to evaluate the timing of occurrence of RBE after common bile duct clearance with ERCP and associated outcomes.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>The records of all patients who underwent ERCP for gallstone disease followed by cholecystectomy, in a single center from 2010 to 2022, were reviewed. All RBE were identified. Actuarial incidence of RBE was built. Patients with and without RBE were compared.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The study population is composed of 529 patients. Mean age was 58.0 (18\u201395). There were 221 RBE in 151 patients (28.5%), 39\/151 (25.8%) having more than one episode. The most frequent RBE was acute cholecystitis (n\u2009=\u2009104) followed by recurrent CBDS (n\u2009=\u200995). Median time for first RBE was 34 days. Actuarial incidence of RBE started from 2.5% at 7 days to reach 53.3% at 1 year. Incidence-rate of RBE was 2.9 per 100 person-months. Patients with RBE had significant longer hospitalisation time (11.7 vs 6.4 days; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001), longer operative time (66 vs 48 min; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001), longer postoperative stay (2.9 vs 0.9 days; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001), higher open surgery rate (7.9% vs 1.3%; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001), and more complicated pathology (23.8% vs 5.8%; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001) and cholecystitis (64.2% vs 25.9%; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001) as final diagnoses.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>RBE occurred in 28.5% of the subjects at a median time of 34 days, with an incidence of 2.5% as early as 1 week. Cholecystectomy should be done preferably within 7 days after common bile duct clearance in order to prevent RBE and adverse outcomes.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00464-023-10423-0","type":"journal-article","created":{"date-parts":[[2023,9,19]],"date-time":"2023-09-19T20:35:37Z","timestamp":1695155737000},"page":"9546-9555","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Delay for cholecystectomy after common bile duct clearance with ERCP is just running after recurrent biliary event"],"prefix":"10.1007","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7482-5801","authenticated-orcid":false,"given":"Eric","family":"Bergeron","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Th\u00e9o","family":"Doyon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thibaut","family":"Mani\u00e8re","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c9tienne","family":"D\u00e9silets","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,9,19]]},"reference":[{"key":"10423_CR1","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.7150\/ijms.52974","volume":"18","author":"Y Wu","year":"2021","unstructured":"Wu Y, Xu CJ, Xu SF (2021) Advances in risk factors for recurrence of common bile duct stones. 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Etienne D\u00e9silets declares payment for lectures for the \u201cAssociation des Gastroenterologues du Qu\u00e9bec\u201d and the \u201cF\u00e9d\u00e9ration des m\u00e9decins sp\u00e9cialistes du Qu\u00e9bec\u201d, but not for this work. Eric Bergeron, Th\u00e9o Doyon, Thibaut Maniere and Etienne D\u00e9silets have no conflicts of interest or financial ties to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}}]}}