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Markar, Nainika Menon, Nadia Guidozzi, Katerina-Maria Kontouli, Dimitrios Mavridis, Alexandros Andreou, Felix Berlth, Luigi Bonavina, Alfred Cushieri, Lana Fourie, James Gossage, Caroline Gronnier, Eric J. Hazebroek, Sheila Krishnadath, Donald E. Low, Mimi McCord, Roos E. Pouw, David I. Watson, Francesco Maria Carrano, Monica Ortenzi and Stavros A. Antoniou declare no direct conflicts of interest related to this work. Indirect conflicts of external advisors were documented and managed as per Guidelines International Network Standards. Detailed conflict of interest statements of all contributors can be found in . A patient version of this guideline is available in Supplementary File 1.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}