{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T20:49:57Z","timestamp":1789591797323,"version":"build-2803163510"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2024,10,9]],"date-time":"2024-10-09T00:00:00Z","timestamp":1728432000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,10,9]],"date-time":"2024-10-09T00:00:00Z","timestamp":1728432000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Ministero della Salute","doi-asserted-by":"publisher","award":["Ricerca corrente 2024"],"award-info":[{"award-number":["Ricerca corrente 2024"]}],"id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004913","name":"Universit\u00e0 degli Studi di Palermo","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004913","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Surg Endosc"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background and Aims<\/jats:title>\n                <jats:p>Post-surgical biliary leaks (PSBL) are one of the most prevalent and significant adverse events emerging after liver or biliary tract surgeries. Endoscopic retrograde cholangiopancreatography (ERCP) alone or combined with another approach (Rendez Vous) as treatment of PSBL obtains optimal outcomes due to the possibility of modifying the resistances in the biliary tree.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>A retrospective double-center study was conducted in two tertiary centers. Consecutive patients who underwent at least one attempt of PSBL correction by ERCP or Rendez Vous procedure between January 2018 and August 2023 were included. The primary outcome was overall endoscopic clinical success. In contrast, the secondary outcomes were hospital stay exceeding five days and endoscopic clinical success with the first endoscopic procedure at the tertiary center. Both univariate and multivariate analyses were used to assess outcomes.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>65 patients were included. Patients with one or multiple) leaks had more possibility to achieve the endoscopic clinical success compared to those affected by the association of leaks and stricture (96% vs 67%, <jats:italic>p<\/jats:italic> value 0.005). Leaks occurring in the main biliary duct had less probability (67%) to achieve the overall endoscopic clinical success compared to those in the end-to-end anastomosis (90%), in the resection plane or biliary stump (96%) or first or secondary order biliary branches (100%, <jats:italic>p<\/jats:italic> value 0.038). A leak-bridging stent positioning had more probability of achieving the endoscopic clinical success than a not leak-bridging stent (91% vs 53%, <jats:italic>p<\/jats:italic> value 0.005).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>ERCP and Rendez Vous procedures are safe and effective for treating PSBL, regardless of the type of preceding surgery, even if technical or clinical success was not achieved on the first attempt. A stent should be placed, if feasible, leak-bridging to enhance treatment efficacy.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Graphical abstract<\/jats:title>\n                \n              <\/jats:sec>","DOI":"10.1007\/s00464-024-11243-6","type":"journal-article","created":{"date-parts":[[2024,10,9]],"date-time":"2024-10-09T16:01:51Z","timestamp":1728489711000},"page":"7233-7242","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Endoscopic or combined management of post-surgical biliary leaks: a two-center recent experience"],"prefix":"10.1007","volume":"38","author":[{"given":"Dario","family":"Quintini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9335-6740","authenticated-orcid":false,"given":"Giacomo Emanuele Maria","family":"Rizzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilaria","family":"Tarantino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giacomo","family":"Sarzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Fantin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Miraglia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Maruzzelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dario","family":"Ligresti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucio","family":"Carrozza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Rancatore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"Gruttadauria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umberto","family":"Cillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Ferrara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Traina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,10,9]]},"reference":[{"issue":"1","key":"11243_CR1","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1007\/s00268-015-3143-0","volume":"40","author":"M Donadon","year":"2016","unstructured":"Donadon M, Costa G, Cimino M, Procopio F, Del Fabbro D, Palmisano A et al (2016) Diagnosis and management of bile leaks after hepatectomy: results of a prospective analysis of 475 hepatectomies. World J Surg 40(1):172\u2013181","journal-title":"World J Surg"},{"issue":"2","key":"11243_CR2","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1097\/XCS.0000000000000039","volume":"234","author":"B G\u00f6rgec","year":"2022","unstructured":"G\u00f6rgec B, Cacciaguerra AB, Aldrighetti LA, Ferrero A, Cillo U, Edwin B et al (2022) Incidence and clinical impact of bile leakage after laparoscopic and open liver resection: an international multicenter propensity score-matched study of 13,379 patients. J Am Coll Surg 234(2):99\u2013112","journal-title":"J Am Coll Surg"},{"issue":"8","key":"11243_CR3","doi-asserted-by":"publisher","first-page":"1898","DOI":"10.1007\/s00268-011-1114-7","volume":"35","author":"R Yoshioka","year":"2011","unstructured":"Yoshioka R, Saiura A, Koga R, Seki M, Kishi Y, Yamamoto J (2011) Predictive factors for bile leakage after hepatectomy: analysis of 505 consecutive patients. World J Surg 35(8):1898\u20131903","journal-title":"World J Surg"},{"issue":"1","key":"11243_CR4","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.hpb.2022.08.009","volume":"25","author":"E Braunwarth","year":"2023","unstructured":"Braunwarth E, Ratti F, Aldrighetti L, Al-Saffar HA, D`Souza MA, Sturesson C et al (2023) Incidence and risk factors for anastomotic bile leakage in hepatic resection with bilioenteric reconstruction \u2013 A international multicenter study. HPB 25(1):54\u201362","journal-title":"HPB"},{"issue":"1","key":"11243_CR5","doi-asserted-by":"publisher","first-page":"e000778","DOI":"10.1136\/bmjgast-2021-000778","volume":"9","author":"M Fasullo","year":"2022","unstructured":"Fasullo M, Patel M, Khanna L, Shah T (2022) Post-transplant biliary complications: advances in pathophysiology, diagnosis, and treatment. BMJ Open Gastroenterol 9(1):e000778","journal-title":"BMJ Open Gastroenterol"},{"issue":"1","key":"11243_CR6","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1186\/s13017-021-00369-w","volume":"16","author":"N DeAngelis","year":"2021","unstructured":"DeAngelis N, Catena F, Memeo R, Coccolini F, Mart\u00ednez-P\u00e9rez A, Romeo OM et al (2021) 2020 WSES guidelines for the detection and management of bile duct injury during cholecystectomy. World J Emerg Surg 16(1):30","journal-title":"World J Emerg Surg"},{"issue":"1","key":"11243_CR7","doi-asserted-by":"publisher","first-page":"66","DOI":"10.4254\/wjh.v13.i1.66","volume":"13","author":"I Boeva","year":"2021","unstructured":"Boeva I, Karagyozov PI, Tishkov I (2021) Post-liver transplant biliary complications: current knowledge and therapeutic advances. World J Hepatol 13(1):66\u201379","journal-title":"World J Hepatol"},{"issue":"9","key":"11243_CR8","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1055\/s-0029-1215050","volume":"41","author":"AY Wang","year":"2009","unstructured":"Wang AY, Ellen K, Berg CL, Schmitt TM, Kahaleh M (2009) Fully covered self-expandable metallic stents in the management of complex biliary leaks: preliminary data - a case series. Endoscopy 41(9):781\u2013786","journal-title":"Endoscopy"},{"issue":"7","key":"11243_CR9","doi-asserted-by":"publisher","first-page":"332","DOI":"10.4253\/wjge.v5.i7.332","volume":"5","author":"D Lalezari","year":"2013","unstructured":"Lalezari D, Singh I, Reicher S, Eysselein VE (2013) Evaluation of fully covered self-expanding metal stents in benign biliary strictures and bile leaks. World J Gastrointest Endosc 5(7):332\u2013339","journal-title":"World J Gastrointest Endosc"},{"issue":"1","key":"11243_CR10","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.gie.2014.11.038","volume":"82","author":"J Canena","year":"2015","unstructured":"Canena J, Liberato M, Meireles L, Marques I, Rom\u00e3o C, Coutinho AP et al (2015) A non-randomized study in consecutive patients with postcholecystectomy refractory biliary leaks who were managed endoscopically with the use of multiple plastic stents or fully covered self-expandable metal stents (with videos). Gastrointest Endosc 82(1):70\u201378","journal-title":"Gastrointest Endosc"},{"issue":"8","key":"11243_CR11","doi-asserted-by":"publisher","first-page":"1191","DOI":"10.14309\/ajg.0000000000000704","volume":"115","author":"DS Ahmad","year":"2020","unstructured":"Ahmad DS, Faulx A (2020) Management of postcholecystectomy biliary complications: a narrative review. Am J Gastroenterol 115(8):1191\u20131198","journal-title":"Am J Gastroenterol"},{"issue":"10","key":"11243_CR12","doi-asserted-by":"publisher","first-page":"e297","DOI":"10.1371\/journal.pmed.0040297","volume":"4","author":"JP Vandenbroucke","year":"2007","unstructured":"Vandenbroucke JP, Von Elm E, Altman DG, G\u00f8tzsche PC, Mulrow CD, Pocock SJ et al (2007) Strengthening the reporting of observational studies in epidemiology (STROBE): explanation and elaboration. PLoS Med 4(10):e297","journal-title":"PLoS Med"},{"issue":"4","key":"11243_CR13","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1016\/j.gie.2016.08.018","volume":"85","author":"DG Adler","year":"2017","unstructured":"Adler DG, Papachristou GI, Taylor LJ, McVay T, Birch M, Francis G et al (2017) Clinical outcomes in patients with bile leaks treated via ERCP with regard to the timing of ERCP: a large multicenter study. Gastrointest Endosc 85(4):766\u2013772","journal-title":"Gastrointest Endosc"},{"issue":"4","key":"11243_CR14","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1016\/j.gie.2012.11.026","volume":"77","author":"SK Tewani","year":"2013","unstructured":"Tewani SK, Turner BG, Chuttani R, Pleskow DK, Sawhney MS (2013) Location of bile leak predicts the success of ERCP performed for postoperative bile leaks. Gastrointest Endosc 77(4):601\u2013608","journal-title":"Gastrointest Endosc"},{"issue":"3","key":"11243_CR15","doi-asserted-by":"publisher","first-page":"512","DOI":"10.4103\/joacp.joacp_535_21","volume":"39","author":"RA Flores-Franco","year":"2023","unstructured":"Flores-Franco RA, Flores-Aguilar DR (2023) A simple model of the Venturi effect with sufficient teaching facts. J Anaesthesiol Clin Pharmacol 39(3):512\u2013513","journal-title":"J Anaesthesiol Clin Pharmacol"},{"issue":"11","key":"11243_CR16","doi-asserted-by":"publisher","first-page":"1074","DOI":"10.1055\/a-0835-5940","volume":"51","author":"K Vlaemynck","year":"2019","unstructured":"Vlaemynck K, Lahousse L, Vanlander A, Piessevaux H, Hindryckx P (2019) Endoscopic management of biliary leaks: a systematic review with meta-analysis. Endoscopy 51(11):1074\u20131081","journal-title":"Endoscopy"},{"issue":"09","key":"11243_CR17","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1055\/a-0659-9864","volume":"50","author":"JM Dumonceau","year":"2018","unstructured":"Dumonceau JM, Tringali A, Papanikolaou I, Blero D, Mangiavillano B, Schmidt A et al (2018) Endoscopic biliary stenting: indications, choice of stents, and results: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline \u2013 Updated October 2017. Endoscopy 50(09):910\u2013930","journal-title":"Endoscopy"},{"issue":"02","key":"11243_CR18","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1055\/a-1075-4080","volume":"52","author":"JM Dumonceau","year":"2020","unstructured":"Dumonceau JM, Kapral C, Aabakken L, Papanikolaou IS, Tringali A, Vanbiervliet G et al (2020) ERCP-related adverse events: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy 52(02):127\u2013149","journal-title":"Endoscopy"},{"issue":"07","key":"11243_CR19","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1055\/s-0042-108641","volume":"48","author":"P Testoni","year":"2016","unstructured":"Testoni P, Mariani A, Aabakken L, Arvanitakis M, Bories E, Costamagna G et al (2016) Papillary cannulation and sphincterotomy techniques at ERCP: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline. Endoscopy 48(07):657\u2013683","journal-title":"Endoscopy"}],"container-title":["Surgical Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00464-024-11243-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00464-024-11243-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00464-024-11243-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T15:10:03Z","timestamp":1736176203000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00464-024-11243-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,9]]},"references-count":19,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["11243"],"URL":"https:\/\/doi.org\/10.1007\/s00464-024-11243-6","relation":{},"ISSN":["0930-2794","1432-2218"],"issn-type":[{"value":"0930-2794","type":"print"},{"value":"1432-2218","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,9]]},"assertion":[{"value":"10 June 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 August 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 October 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Drs. Dario Quintini, Dr. Giacomo Emanuele Maria Rizzo, Dr. Ilaria Tarantino, Dr. Giacomo Sarzo, Dr. Alberto Fantin, Dr. Roberto Miraglia, Dr. Luigi Maruzzelli, Dr. Dario Ligresti, Dr. Lucio Carrozza, Dr. Gabriele Rancatore, Dr. Salvatore Gruttadauria, Dr. Umberto Cillo, Dr. Francesco Ferrara, and Dr Mario Traina have no conflicts of interest or financial ties to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}}]}}