{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T17:57:31Z","timestamp":1781978251038,"version":"3.54.5"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,10,4]],"date-time":"2024-10-04T00:00:00Z","timestamp":1728000000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,10,4]],"date-time":"2024-10-04T00:00:00Z","timestamp":1728000000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Surg Endosc"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Introduction<\/jats:title>\n                <jats:p>Obesity is a major risk factor for idiopathic intracranial hypertension (IIH). Effective therapeutics for preventing disease progression and alleviating symptoms are limited. This study aims to examine the effects of bariatric surgery on clinical outcomes of IIH.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>We retrospectively collected data from the medical record of 97 patients with obesity and an existing diagnosis of IIH who underwent primary bariatric surgery at the Cleveland Clinic health system in the USA between 2005 and 2023. Pre- and postoperative data on presence of symptoms and clinical markers of IIH (headaches, visual field defects, papilledema, visual symptoms), intracranial pressure, and\u00a0usage of IIH medications were compared.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>A total of 97 patients (98% female, median age 46.7\u00a0years, median BMI 48.3\u00a0kg\/m<jats:sup>2<\/jats:sup>) with IIH who underwent bariatric surgery including Roux-en-Y gastric bypass (<jats:italic>n<\/jats:italic>\u2009=\u200966, 68%), sleeve gastrectomy (<jats:italic>n<\/jats:italic>\u2009=\u200927, 27.8%), and gastric banding (<jats:italic>n<\/jats:italic>\u2009=\u20094, 4.1%) were analyzed. In a median follow-up time of 3.0\u00a0years, the median total weight loss was 24% (interquartile range, 13\u201333%). There was a significant improvement in headache, papilledema, visual field deficits, and visual symptoms after bariatric surgery. The mean lumbar opening pressure before and after bariatric surgery was 34.8\u2009\u00b1\u20098.2\u00a0cm CSF and 24.2\u2009\u00b1\u20097.6\u00a0cm CSF, respectively, with a mean reduction of 10.7 cm CSF (95% confidence interval, 4.7 to 16.6), <jats:italic>p<\/jats:italic>\u2009=\u20090.003. The dosage of acetazolamide and topiramate, as well as the number of medications taken for IIH, decreased significantly after bariatric surgery (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>For patients who have obesity, bariatric surgery is a viable treatment modality for alleviation or improvement of symptoms of IIH.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00464-024-11254-3","type":"journal-article","created":{"date-parts":[[2024,10,4]],"date-time":"2024-10-04T15:02:01Z","timestamp":1728054121000},"page":"425-431","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Clinical outcomes of bariatric surgery in patients with obesity and idiopathic intracranial hypertension"],"prefix":"10.1007","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4414-0446","authenticated-orcid":false,"given":"M\u00e9lissa V.","family":"Wills","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Hesam","family":"Alavi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Essa M.","family":"Aleassa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Tu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rickesha","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricard","family":"Corcelles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toms","family":"Augustin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalman P.","family":"Bencsath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter","family":"Cha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesse","family":"Gutnick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Szomstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raul","family":"Rosenthal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Kroh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxi","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Aminian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,10,4]]},"reference":[{"issue":"1","key":"11254_CR1","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/S1474-4422(15)00298-7","volume":"15","author":"KA Markey","year":"2016","unstructured":"Markey KA, Mollan SP, Jensen RH, Sinclair AJ (2016) Understanding idiopathic intracranial hypertension: mechanisms, management, and future directions. 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Raul Rosenthal, MD reported receiving personal fees from Medtronic, Diagnostic Green, Medicad simulation, and Dendrite Imaging and serving as the interim CEO of Dendrite Imaging. M\u00e9lissa V Wills, MD, Mohammad Hesam Alavi, MD MPH, Essa M Aleassa, MD, Chao Tu, BS, Rickesha Wilson, MD, Ricard Corcelles, MD, Toms Augustin, MD, Kalman P Bencsath, MD, Walter Cha, MD, Jesse Gutnick, MD, Samuel Szomstein, MD, Matthew Kroh, MD, and Xiaoxi Feng, MD have no conflicts of interest or financial ties to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}}]}}