{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T04:14:31Z","timestamp":1751516071521,"version":"3.41.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T00:00:00Z","timestamp":1748995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T00:00:00Z","timestamp":1748995200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Surg Endosc"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1007\/s00464-025-11822-1","type":"journal-article","created":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T14:53:56Z","timestamp":1749048836000},"page":"4432-4446","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Optimal lymph node dissection thresholds for early-stage esophageal squamous cell carcinoma: a retrospective multicenter study"],"prefix":"10.1007","volume":"39","author":[{"given":"Donghui","family":"Jin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hang","family":"Yi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haibo","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guochao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1120-241X","authenticated-orcid":false,"given":"Yousheng","family":"Mao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenqun","family":"Xing","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,6,4]]},"reference":[{"issue":"3","key":"11822_CR1","doi-asserted-by":"publisher","first-page":"209","DOI":"10.3322\/caac.21660","volume":"71","author":"H Sung","year":"2021","unstructured":"Sung H, Ferlay J, Siegel RL et al (2021) Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 71(3):209\u2013249. https:\/\/doi.org\/10.3322\/caac.21660","journal-title":"CA Cancer J Clin"},{"issue":"1","key":"11822_CR2","first-page":"22","volume":"95","author":"MW Short","year":"2017","unstructured":"Short MW, Burgers KG, Fry VT (2017) Esophageal cancer. Am Fam Physician 95(1):22\u201328","journal-title":"Am Fam Physician"},{"issue":"1","key":"11822_CR3","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1186\/s12885-021-07867-9","volume":"21","author":"D Chen","year":"2021","unstructured":"Chen D, Wang W, Mo J et al (2021) Minimal invasive versus open esophagectomy for patients with esophageal squamous cell carcinoma after neoadjuvant treatments. BMC Cancer 21(1):145. https:\/\/doi.org\/10.1186\/s12885-021-07867-9","journal-title":"BMC Cancer"},{"issue":"1","key":"11822_CR4","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.jtho.2016.10.016","volume":"12","author":"TW Rice","year":"2017","unstructured":"Rice TW, Ishwaran H, Ferguson MK et al (2017) Cancer of the esophagus and esophagogastric junction: an eighth edition staging primer. J Thorac Oncol 12(1):36\u201342. https:\/\/doi.org\/10.1016\/j.jtho.2016.10.016","journal-title":"J Thorac Oncol"},{"key":"11822_CR5","doi-asserted-by":"publisher","first-page":"106764","DOI":"10.1016\/j.ijsu.2022.106764","volume":"104","author":"D Tian","year":"2022","unstructured":"Tian D, Li HX, Yang YS et al (2022) The minimum number of examined lymph nodes for accurate nodal staging and optimal survival of stage T1\u20132 esophageal squamous cell carcinoma: a retrospective multicenter cohort with SEER database validation. Int J Surg 104:106764. https:\/\/doi.org\/10.1016\/j.ijsu.2022.106764","journal-title":"Int J Surg"},{"issue":"2","key":"11822_CR6","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1016\/j.surg.2012.08.001","volume":"153","author":"Y Baba","year":"2013","unstructured":"Baba Y, Watanabe M, Shigaki H et al (2013) Negative lymph-node count is associated with survival in patients with resected esophageal squamous cell carcinoma. Surgery 153(2):234\u2013241. https:\/\/doi.org\/10.1016\/j.surg.2012.08.001","journal-title":"Surgery"},{"issue":"2","key":"11822_CR7","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1097\/SLA.0b013e31817bbe59","volume":"248","author":"NK Altorki","year":"2008","unstructured":"Altorki NK, Zhou XK, Stiles B et al (2008) Total number of resected lymph nodes predicts survival in esophageal cancer. Ann Surg 248(2):221\u2013226. https:\/\/doi.org\/10.1097\/SLA.0b013e31817bbe59","journal-title":"Ann Surg"},{"issue":"4","key":"11822_CR8","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1097\/SLA.0b013e318188c474","volume":"248","author":"CG Peyre","year":"2008","unstructured":"Peyre CG, Hagen JA, Demeester SR et al (2008) The number of lymph nodes removed predicts survival in esophageal cancer: an international study on the impact of extent of surgical resection. Ann Surg 248(4):549\u2013556. https:\/\/doi.org\/10.1097\/SLA.0b013e318188c474","journal-title":"Ann Surg"},{"issue":"1","key":"11822_CR9","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1111\/j.1442-2050.2010.01086.x","volume":"24","author":"Y Tachimori","year":"2011","unstructured":"Tachimori Y, Nagai Y, Kanamori N et al (2011) Pattern of lymph node metastases of esophageal squamous cell carcinoma based on the anatomical lymphatic drainage system. Dis Esophagus 24(1):33\u201338. https:\/\/doi.org\/10.1111\/j.1442-2050.2010.01086.x","journal-title":"Dis Esophagus"},{"issue":"7","key":"11822_CR10","doi-asserted-by":"publisher","first-page":"3625","DOI":"10.1007\/s00464-024-10853-4","volume":"38","author":"Y Koterazawa","year":"2024","unstructured":"Koterazawa Y, Goto H, Saiga H et al (2024) The number of resected lymph nodes from the upper mediastinal area predicts long-term outcomes of esophageal squamous cell carcinoma after minimally invasive esophagectomy. Surg Endosc 38(7):3625\u20133635. https:\/\/doi.org\/10.1007\/s00464-024-10853-4","journal-title":"Surg Endosc"},{"issue":"13","key":"11822_CR11","doi-asserted-by":"publisher","first-page":"3743","DOI":"10.1245\/s10434-011-1753-9","volume":"18","author":"C Castoro","year":"2011","unstructured":"Castoro C, Scarpa M, Cagol M et al (2011) Nodal metastasis from locally advanced esophageal cancer: how neoadjuvant therapy modifies their frequency and distribution. Ann Surg Oncol 18(13):3743\u20133754. https:\/\/doi.org\/10.1245\/s10434-011-1753-9","journal-title":"Ann Surg Oncol"},{"issue":"9","key":"11822_CR12","doi-asserted-by":"publisher","first-page":"3038","DOI":"10.1245\/s10434-013-2988-4","volume":"20","author":"R Shridhar","year":"2013","unstructured":"Shridhar R, Hoffe SE, Almhanna K et al (2013) Lymph node harvest in esophageal cancer after neoadjuvant chemoradiotherapy. Ann Surg Oncol 20(9):3038\u20133043. https:\/\/doi.org\/10.1245\/s10434-013-2988-4","journal-title":"Ann Surg Oncol"},{"issue":"9","key":"11822_CR13","doi-asserted-by":"publisher","first-page":"2857","DOI":"10.1245\/s10434-014-3665-y","volume":"21","author":"Z Zhu","year":"2014","unstructured":"Zhu Z, Chen H, Yu W et al (2014) Number of negative lymph nodes is associated with survival in thoracic esophageal squamous cell carcinoma patients undergoing three-field lymphadenectomy. Ann Surg Oncol 21(9):2857\u20132863. https:\/\/doi.org\/10.1245\/s10434-014-3665-y","journal-title":"Ann Surg Oncol"},{"issue":"1","key":"11822_CR14","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1186\/s12885-021-08080-4","volume":"21","author":"Y Wang","year":"2021","unstructured":"Wang Y, Zhang X, Zhang X et al (2021) Prognostic value of the extent of lymphadenectomy for esophageal cancer-specific survival among T1 patients. BMC Cancer 21(1):403. https:\/\/doi.org\/10.1186\/s12885-021-08080-4","journal-title":"BMC Cancer"},{"key":"11822_CR15","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/603194","volume":"2014","author":"W Song","year":"2014","unstructured":"Song W, Yuan Y, Wang L et al (2014) The prognostic value of lymph nodes dissection number on survival of patients with lymph node-negative gastric cancer. Gastroenterol Res Pract 2014:603194. https:\/\/doi.org\/10.1155\/2014\/603194","journal-title":"Gastroenterol Res Pract"},{"issue":"Suppl 8","key":"11822_CR16","doi-asserted-by":"publisher","first-page":"S724","DOI":"10.21037\/jtd.2017.06.19","volume":"9","author":"Y Tachimori","year":"2017","unstructured":"Tachimori Y (2017) Pattern of lymph node metastases of squamous cell esophageal cancer based on the anatomical lymphatic drainage system: efficacy of lymph node dissection according to tumor location. J Thorac Dis 9(Suppl 8):S724\u2013S730. https:\/\/doi.org\/10.21037\/jtd.2017.06.19","journal-title":"J Thorac Dis"},{"issue":"2","key":"11822_CR17","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1007\/BF00294412","volume":"18","author":"H Fujita","year":"1994","unstructured":"Fujita H, Kakegawa T, Yamana H et al (1994) Lymph node metastasis and recurrence in patients with a carcinoma of the thoracic esophagus who underwent three-field dissection. World J Surg 18(2):266\u2013272. https:\/\/doi.org\/10.1007\/BF00294412","journal-title":"World J Surg"},{"issue":"6","key":"11822_CR18","doi-asserted-by":"publisher","first-page":"1343","DOI":"10.1016\/s0022-5223(03)00036-9","volume":"125","author":"K Kuge","year":"2003","unstructured":"Kuge K, Murakami G, Mizobuchi S et al (2003) Submucosal territory of the direct lymphatic drainage system to the thoracic duct in the human esophagus. J Thorac Cardiovasc Surg 125(6):1343\u20131349. https:\/\/doi.org\/10.1016\/s0022-5223(03)00036-9","journal-title":"J Thorac Cardiovasc Surg"},{"key":"11822_CR19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s10388-015-0515-3","volume":"13","author":"Y Tachimori","year":"2016","unstructured":"Tachimori Y, Ozawa S, Numasaki H et al (2016) Efficacy of lymph node dissection by node zones according to tumor location for esophageal squamous cell carcinoma. Esophagus 13:1\u20137. https:\/\/doi.org\/10.1007\/s10388-015-0515-3","journal-title":"Esophagus"},{"issue":"1","key":"11822_CR20","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1002\/1096-9098(200009)75:1<37::aid-jso7>3.0.co;2-5","volume":"75","author":"H Igaki","year":"2000","unstructured":"Igaki H, Kato H, Tachimori Y et al (2000) Cervical lymph node metastasis in patients with submucosal carcinoma of the thoracic esophagus. J Surg Oncol 75(1):37\u201341. https:\/\/doi.org\/10.1002\/1096-9098(200009)75:1%3c37::aid-jso7%3e3.0.co;2-5","journal-title":"J Surg Oncol"},{"issue":"2","key":"11822_CR21","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1016\/j.ejcts.2006.10.033","volume":"31","author":"CH Kang","year":"2007","unstructured":"Kang CH, Kim YT, Jeon SH et al (2007) Lymphadenectomy extent is closely related to long-term survival in esophageal cancer. Eur J Cardiothorac Surg 31(2):154\u2013160. https:\/\/doi.org\/10.1016\/j.ejcts.2006.10.033","journal-title":"Eur J Cardiothorac Surg"},{"issue":"2","key":"11822_CR22","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1097\/sla.0000000000002824","volume":"269","author":"E Visser","year":"2019","unstructured":"Visser E, Markar SR, Ruurda JP et al (2019) Prognostic value of lymph node yield on overall survival in esophageal cancer patients: a systematic review and meta-analysis. Ann Surg 269(2):261\u2013268. https:\/\/doi.org\/10.1097\/sla.0000000000002824","journal-title":"Ann Surg"},{"key":"11822_CR23","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djv043","author":"M Van Der Schaaf","year":"2015","unstructured":"Van Der Schaaf M, Johar A, Wijnhoven B et al (2015) Extent of lymph node removal during esophageal cancer surgery and survival. J Natl Cancer Inst. https:\/\/doi.org\/10.1093\/jnci\/djv043","journal-title":"J Natl Cancer Inst"},{"issue":"1","key":"11822_CR24","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1001\/jamasurg.2015.2611","volume":"151","author":"J Lagergren","year":"2016","unstructured":"Lagergren J, Mattsson F, Zylstra J et al (2016) Extent of lymphadenectomy and prognosis after esophageal cancer surgery. JAMA Surg 151(1):32\u201339. https:\/\/doi.org\/10.1001\/jamasurg.2015.2611","journal-title":"JAMA Surg"},{"issue":"3","key":"11822_CR25","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1016\/s1072-7515(01)01177-2","volume":"194","author":"SM Griffin","year":"2002","unstructured":"Griffin SM, Shaw IH, Dresner SM (2002) Early complications after Ivor Lewis subtotal esophagectomy with two-field lymphadenectomy: risk factors and management. J Am Coll Surg 194(3):285\u2013297. https:\/\/doi.org\/10.1016\/s1072-7515(01)01177-2","journal-title":"J Am Coll Surg"}],"container-title":["Surgical Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00464-025-11822-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00464-025-11822-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00464-025-11822-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T17:38:28Z","timestamp":1751477908000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00464-025-11822-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,4]]},"references-count":25,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["11822"],"URL":"https:\/\/doi.org\/10.1007\/s00464-025-11822-1","relation":{},"ISSN":["0930-2794","1432-2218"],"issn-type":[{"type":"print","value":"0930-2794"},{"type":"electronic","value":"1432-2218"}],"subject":[],"published":{"date-parts":[[2025,6,4]]},"assertion":[{"value":"29 December 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 May 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 June 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Drs. Donghui Jin, Hang Yi, Haibo Sun, Guochao Zhang, Yan Zheng, Yousheng Mao and Wenqun Xing have no conflicts of interest or financial ties to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}}]}}