{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T05:09:46Z","timestamp":1781932186107,"version":"3.54.5"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T00:00:00Z","timestamp":1751414400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T00:00:00Z","timestamp":1751414400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"St. Joseph's Foundation - A Dignity Health Member"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Surg Endosc"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Post-laparoscopic shoulder pain (PLSP) is a significant source of postoperative morbidity after hiatal hernia repair and antireflux surgery. We evaluated whether adjunctive pain relief strategies\u2014instillation of 0.25% bupivacaine over the left hemidiaphragm or postoperative back massager use\u2014reduced opioid use or pain severity after laparoscopic antireflux surgery (LARS).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>This single-center, randomized, open-label trial included patients who underwent elective primary LARS between May 2021 and April 2024. Participants were randomly assigned (1:1:1) to one of three groups: A, standard medication regimen; B, standard\u2009+\u2009intraoperative instillation of 0.25% bupivacaine over the left hemidiaphragm; or C, standard\u2009+\u2009back massager use. Primary outcomes included overall pain and postoperative use of opioids. The secondary outcomes were pain frequency and severity by anatomical location. Assessments were performed 1, 3, 6, 24, 72, and 168\u00a0h after surgery. This trial was registered (ClinicalTrials.gov: NCT04936711) and is now complete.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Forty-three patients were randomized to groups A (n\u2009=\u200916), B (n\u2009=\u200910), and C (n\u2009=\u200917). One had a postoperative complication, and four were excluded (missing data: n\u2009=\u20092, incorrect massager use: n\u2009=\u20092), leaving 38 per-protocol patients (A: 16, B: 9, C: 13). The median age was 66\u00a0years (IQR 57\u201369), median BMI 28.4\u00a0kg\/m<jats:sup>2<\/jats:sup> (IQR 25.5\u201331.2), and 68.4% were female. Incidence of PLSP within 7\u00a0days was 97.6%. Overall, 84.2% required opioids with the lowest use in group B (A: 100%, B: 55.6%, C: 84.6%; p\u2009=\u20090.014). Group B also had lower rates of PLSP at 1\u00a0h (A: 75%, B: 44.4%, C: 88.2%; p\u2009=\u20090.025) as well as any pain at 3\u00a0h (A: 81.3%, B: 66.7%, C: 100%; p\u2009=\u20090.049).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>PLSP is very common after LARS. Intraoperative bupivacaine instillation at the diaphragm reduced opioid use and pain severity in the immediate postoperative period, while back massagers provided no additional benefit.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00464-025-11939-3","type":"journal-article","created":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T16:00:36Z","timestamp":1751472036000},"page":"5355-5366","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Shoulder pain after laparoscopic antireflux surgery: a single-center, randomized, open-label trial"],"prefix":"10.1007","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2760-3891","authenticated-orcid":false,"given":"Sumeet K.","family":"Mittal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3401-8623","authenticated-orcid":false,"given":"Andr\u00e9s R.","family":"Latorre-Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2216-9109","authenticated-orcid":false,"given":"Ross M.","family":"Bremner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,7,2]]},"reference":[{"key":"11939_CR1","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1097\/JCMA.0000000000000190","volume":"82","author":"CH Sao","year":"2019","unstructured":"Sao CH, Chan-Tiopianco M, Chung KC, Chen YJ, Horng HC, Lee WL, Wang PH (2019) Pain after laparoscopic surgery: focus on shoulder-tip pain after gynecological laparoscopic surgery. 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