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Subsequent technical developments, including intracorporeal anastomosis, complete mesocolic excision (CME), refined pathologic grading systems and robotic approaches are increasingly used despite minimal supporting evidence. This international phase II trial aims to assess patient, surgical and pathological outcomes following robotic (RRHC) with laparoscopic right hemicolectomy (LRHC) for right sided colon cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Prospective, international multicentre pilot randomised phase II trial for patients with right colon adenocarcinoma, randomised 2:1 to robotic (RRHC) or laparoscopic (LRHC) surgery performed by accredited surgeons. Primary outcome was 90-day surgical morbidity measured using the Comprehensive Complication Index (CCI). Standardised pathology reviews, patient reported quality of life and surgeon task load index data was captured.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      RRHC vs. LRHC surgery allocation was 19 vs. 10, mean operative time 3.8 vs. 3.1 h with no operative mortality, all had R0 resection, CME rate 53 vs. 50% and intact mesocolon 94 v 100%. CCI was significantly lower at 30 and 90 days after RRHC (median (Q1, Q3): 0 (0, 9) vs. 21 (21, 26); median difference: 21; 95% CI 9\u201326;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005 at 30 days;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.008 at 90 days). No significant differences in pathological nor quality of life data was observed. Surgeons task load data tended to favour robotic procedures. Median follow-up was 6 months. Limited funding led to early study closure.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>RRHC improved short-term surgical morbidity and surgeon physical demand and performance whilst obtaining similar quality of life and pathological specimen quality compared to LRHC for right sided colon cancer, supporting the case for larger randomised trials.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial registration<\/jats:title>\n                    <jats:p>ACTRN12620001378910<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Graphical Abstract<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1007\/s00464-025-12400-1","type":"journal-article","created":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T19:50:18Z","timestamp":1765396218000},"page":"2062-2077","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["RoLaCaRT-1: pilot randomised phase II study of robotic vs laparoscopic hemicolectomy for right colon cancer"],"prefix":"10.1007","volume":"40","clinical-trial-number":[{"clinical-trial-number":"actrn12620001378910","registry":"10.18810\/anzctr"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5639-3526","authenticated-orcid":false,"given":"Andrew R. 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Professor Jim S Khan performs proctoring for Intuitive Surgical and educational activity with Johnson & Johnson. Dr Stephen Pillinger performs\u00a0proctoring for Device Technologies\/Intuitive Surgical; Director of TR300 and TR400 Training Courses for Intuitive Surgical. Dr Craig Lynch performs proctoring for Device Technologies and Medtronics. Professor Danilo Miskovic performs proctoring for Intuitive Surgical. Dr Carina F K Chow performs proctoring for Device Technologies\/Intuitive Surgical. Faculty of TR 300 and 400 Training Courses for Intuitive Surgical. Dr Darren Tonkin performs proctoring for Device Technologies and Medtronic. Ms Kate Wilson, Dr Rachel O\u2019Connell, Professor Nader Francis, Dr Nathan Curtis, Dr Andrew Clouston, Dr Gregory Miller, Associate Professor Satish Warrier, Professor Alexander Heriot, Associate Professor Stephen Bell, Associate Professor Mark Muhlmann, Dr Kirk Austin, Dr Chris Gillespie, Professor David Larson, Professor Larissa Temple, Professor Alessio Pigazzi and Dr Rebecca Mercieca-Bebber have no conflicts of interest or financial ties to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}}]}}