{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T06:14:13Z","timestamp":1787724853383,"version":"build-2784847793"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T00:00:00Z","timestamp":1766966400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T00:00:00Z","timestamp":1766966400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100006034","name":"University of Southern California","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100006034","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Surg Endosc"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Anastomotic leak is a serious complication of bowel anastomosis, with multifactorial etiology. Thorough intraoperative evaluation of the anastomosis using white light endoscopy and leak tests is critical. Indocyanine green fluorescence angiography (ICG-FA) has emerged as a tool to assess bowel perfusion, but has limitations, including patient allergies and procedural complexity. The FUJIFILM ELUXEO\u00ae VISION Endoscopic Imaging System uses oxygen saturation imaging (OSI) to measure tissue oxygen saturation (StO\n                      <jats:sub>2<\/jats:sub>\n                      ) in real time, without requiring dye injection. This study investigates a novel quantitative approach for assessing bowel perfusion endoscopically by evaluating StO\n                      <jats:sub>2<\/jats:sub>\n                      at colon anastomoses.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The FUJIFILM VISION was used to obtain intraoperative mucosal StO\n                      <jats:sub>2<\/jats:sub>\n                      measurements in 12 patients\u2019 post-colon resection with anastomosis. Measurements were taken at four locations: proximal base, proximal staple line, distal staple line, and distal base. Two-tailed paired\n                      <jats:italic>t<\/jats:italic>\n                      tests were used to compare StO\n                      <jats:sub>2<\/jats:sub>\n                      measurements at distant healthy mucosa (base) to the staple line, both proximal and distal to the anastomosis. Patients were followed longitudinally via chart review to monitor outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The average StO\n                      <jats:sub>2<\/jats:sub>\n                      differences were +\u00a012.58% (95% CI 1.96\u00a0\u2013\u00a023.19%) between the proximal base and proximal staple line and +\u00a015.34% (95% CI 6.76\u00a0\u2013\u00a023.9%) between the distal base and distal staple line. Significant StO\n                      <jats:sub>2<\/jats:sub>\n                      differences were observed between baseline normal mucosa and staple line adjacent mucosa (proximal:\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.025; distal:\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003). No patients had intraoperative complications or developed anastomotic leaks during the study.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      This study shows that the ELUXEO\u00ae VISION Endoscopic Imaging System is a potentially useful tool for providing quantitative data on tissue perfusion at and near anastomotic sites, complementing traditional white light endoscopy and leak tests. Larger prospective studies with long-term follow-up are needed to confirm the relationship between StO\n                      <jats:sub>2<\/jats:sub>\n                      measurements and clinical outcomes such as anastomotic leaks and stricture.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00464-025-12526-2","type":"journal-article","created":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T16:29:28Z","timestamp":1767025768000},"page":"1704-1710","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Real-time bowel perfusion monitoring with FUJIFILM ELUXEO\u00ae VISION endoscopic imaging system in colorectal surgery"],"prefix":"10.1007","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-3971-750X","authenticated-orcid":false,"given":"Jordan","family":"Martucci","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aubrey","family":"Swinford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhinav","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexis","family":"Peters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sacha","family":"Broccard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle G.","family":"Cologne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joongho","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang W.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,29]]},"reference":[{"issue":"12","key":"12526_CR1","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1038\/nrgastro.2009.185","volume":"6","author":"G Nandakumar","year":"2009","unstructured":"Nandakumar G, Stein SL, Michelassi F (2009) Anastomoses of the lower gastrointestinal tract. 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Cologne, and Joongho Shin have no conflicts of interest or financial ties to disclose. Sang W. Lee reports receiving a research grant from FUJIFILM for data collection, serves as a Consultant for Noah Medical, and holds a patent with Guard Medical.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclosures"}},{"value":"All procedures performed in the study involving human subjects were in accordance with the ethical standards of the institutional review board at the University of Southern California, which granted a waiver of consent.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}