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Masafumi Inomata received research funding from Olympus Corporation for collaborative work. Olympus Corporation had no role in the study design, data analysis, interpretation, or manuscript preparation. Takumi Hasegawa, Tsuyoshi Etoh, Tomoki Nakano, Yusuke Matsunobu, Reo Fujishima, Syunsuke Fujita, Yuki Shitomi, Tomonori Akagi, Shigeo Ninomiya, Yoshitake Ueda, and Tatsushi Tokuyasu have no conflicts of interest or financial ties to disclose.","order":1,"name":"Ethics","label":"Disclosures","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The protocol for this research project has been approved by a suitably constituted Ethics Committee of the institution and it conforms to the provisions of the Declaration of Helsinki. Approval was granted by the Oita University Faculty of Medicine Ethics Committee (approval number: 2772-D25) and the institutional review boards of all participating institutions. 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