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Hospitalizations for pancreatitis are common before TPIAT. However, data comparing hospitalization patterns before and after TPIAT remain limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This multicenter, prospective observational study of TPIAT (POST) enrolled 380 patients (age 26 (15, 43\u00a0years), 34% pediatric, 62% female) from 12 centers who underwent TPIAT for CP or RAP. Data were collected through patient self-report and electronic medical record confirmation for an 18-month period pre-TPIAT and post-TPIAT at 6\u00a0months, 1\u00a0year, and then yearly up to 4\u00a0years after TPIAT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Proportion of participants reporting any hospitalizations and median hospitalizations per year decreased after TPIAT. Percent with hospital admissions decreased from 86.8% in the 18\u00a0months prior to TPIAT to 47.3%, 31.2%, 31% and 30.8% at 1-, 2-, 3-, and 4-year follow-up intervals, respectively, with median hospitalizations per year decreasing from 2 (1, 4) to 0 (0, 2) at 1\u00a0year and 0 (0, 1) at each of 2-, 3-, and 4-year post-TPIAT (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001 for all). Median cumulative days in hospital decreased from 8 to 0\u00a0days at all intervals (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001 for all). Hospitalization risk was increased with ongoing opioid use at the 1\u20132-year and 2\u20133-year follow-up intervals (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.009 and\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005) but was not associated with insulin use post-TPIAT. Emergency department and office visits decreased after TPIAT at all follow-up intervals (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) as did proportion of participants with cross-sectional imaging. Abdominal reoperations occurred in about 38% by Kaplan\u2013Meier estimate by 4\u00a0years post-TPIAT.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Hospitalizations, emergency room visits, and office visits decreased after TPIAT when compared to baseline. Persistent opioid use after TPIAT was associated with increased admissions up to 3\u00a0years post-TPIAT.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00464-026-13228-z","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:09:50Z","timestamp":1787764190000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Rates of hospitalization pre- and post-total pancreatectomy with islet autotransplantation for patients with pancreatitis"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-8804-6815","authenticated-orcid":false,"given":"Niveditha","family":"Jagadesh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Eaton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan B.","family":"Ghai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guru","family":"Trikudanathan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn D.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikesh K.","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaimie D.","family":"Nathan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srinath","family":"Chinnakotla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maisam","family":"Abu-El-Haija","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed A.","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy B.","family":"Gardner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis F.","family":"Lara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Morgan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sri Prakash","family":"Mokshagundam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bashoo","family":"Naziruddin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Posselt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Wijkstrom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Witkowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory","family":"Beilman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melena D.","family":"Bellin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,8,26]]},"reference":[{"issue":"8","key":"13228_CR1","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1016\/j.pan.2022.10.004","volume":"22","author":"VK Singh","year":"2022","unstructured":"Singh VK, Whitcomb DC, Banks PA, AlKaade S, Anderson MA, Amann ST et al (2022) Acute pancreatitis precedes chronic pancreatitis in the majority of patients: results from the NAPS2 consortium. 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