{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T19:05:19Z","timestamp":1789585519263,"version":"build-2803163510"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Surg Endosc"],"DOI":"10.1007\/s00464-026-13376-2","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T18:41:25Z","timestamp":1789584085000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A pilot study on the efficacy of cyanoacrylate glue in preventing post-ESD bleeding at the gastric angle"],"prefix":"10.1007","author":[{"given":"Fengcheng","family":"Zang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunfu","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luojie","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,16]]},"reference":[{"issue":"1","key":"13376_CR1","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1111\/den.13883","volume":"33","author":"H Ono","year":"2021","unstructured":"Ono H, Yao K, Fujishiro M et al (2021) Guidelines for endoscopic submucosal dissection and endoscopic mucosal resection for early gastric cancer (second edition). Dig Endosc 33(1):4\u201320. https:\/\/doi.org\/10.1111\/den.13883","journal-title":"Dig Endosc"},{"issue":"3","key":"13376_CR2","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1016\/j.gie.2019.05.018","volume":"90","author":"D Yang","year":"2019","unstructured":"Yang D, Kotzev AI, Draganov PV (2019) Endoscopic submucosal dissection for early gastric cancer in the west: the absolute but not final word. Gastrointest Endosc 90(3):480\u2013482. https:\/\/doi.org\/10.1016\/j.gie.2019.05.018","journal-title":"Gastrointest Endosc"},{"issue":"5","key":"13376_CR3","doi-asserted-by":"publisher","first-page":"677","DOI":"10.5009\/gnl250113","volume":"19","author":"TS Kim","year":"2025","unstructured":"Kim TS, Kim TJ, Min YW et al (2025) A randomized controlled trial to evaluate the effect of fibrin glue on bleeding after gastric endoscopic submucosal dissection. Gut Liver 19(5):677\u2013684. https:\/\/doi.org\/10.5009\/gnl250113","journal-title":"Gut Liver"},{"issue":"6","key":"13376_CR4","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1159\/000446252","volume":"33","author":"ES Tan","year":"2016","unstructured":"Tan ES, Wang H, Lua GW et al (2016) Fibrin glue spray as a simple and promising method to prevent bleeding after gastric endoscopic submucosal dissection. Dig Surg 33(6):455\u2013461. https:\/\/doi.org\/10.1159\/000446252","journal-title":"Dig Surg"},{"issue":"10","key":"13376_CR5","doi-asserted-by":"publisher","first-page":"1150","DOI":"10.1055\/a-2646-7556","volume":"57","author":"IM Gralnek","year":"2025","unstructured":"Gralnek IM, Bhandari P, Alkandari A et al (2025) Topical hemostatic agents in endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) technical and technology review. Endoscopy 57(10):1150\u20131173. https:\/\/doi.org\/10.1055\/a-2646-7556","journal-title":"Endoscopy"},{"issue":"11","key":"13376_CR6","doi-asserted-by":"publisher","first-page":"1814","DOI":"10.1136\/gutjnl-2024-334463","volume":"74","author":"A Miyakawa","year":"2025","unstructured":"Miyakawa A, Tamaru Y, Mizumoto T et al (2025) Prophylactic clip closure after endoscopic submucosal dissection of large flat and sessile colorectal polyps: a multicentre randomised controlled trial (EPOC trial). Gut 74(11):1814\u20131820. https:\/\/doi.org\/10.1136\/gutjnl-2024-334463","journal-title":"Gut"},{"issue":"5","key":"13376_CR7","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD010180.pub2","volume":"2015","author":"E R\u00edos Castellanos","year":"2015","unstructured":"R\u00edos Castellanos E, Seron P, Gisbert JP et al (2015) Endoscopic injection of cyanoacrylate glue versus other endoscopic procedures for acute bleeding gastric varices in people with portal hypertension. Cochrane Database Syst Rev 2015(5):CD010180. https:\/\/doi.org\/10.1002\/14651858.CD010180.pub2","journal-title":"Cochrane Database Syst Rev"},{"issue":"1","key":"13376_CR8","doi-asserted-by":"publisher","first-page":"84","DOI":"10.4103\/EUS-D-22-00006","volume":"12","author":"L Tang","year":"2023","unstructured":"Tang L, Li X, Cui J et al (2023) EUS-guided coil placement and cyanoacrylate glue injection for gastric variceal bleeding with obvious spontaneous portosystemic shunts. Endosc Ultrasound 12(1):84\u201389. https:\/\/doi.org\/10.4103\/EUS-D-22-00006","journal-title":"Endosc Ultrasound"},{"issue":"11","key":"13376_CR9","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1055\/s-2002-35312","volume":"34","author":"S Seewald","year":"2002","unstructured":"Seewald S, Sriram PV, Naga M et al (2002) Cyanoacrylate glue in gastric variceal bleeding. Endoscopy 34(11):926\u2013932. https:\/\/doi.org\/10.1055\/s-2002-35312","journal-title":"Endoscopy"},{"issue":"11","key":"13376_CR10","doi-asserted-by":"publisher","first-page":"2141","DOI":"10.1007\/s00384-020-03678-9","volume":"35","author":"G Martines","year":"2020","unstructured":"Martines G, Picciariello A, Dibra R et al (2020) Efficacy of cyanoacrylate in the prevention of delayed bleeding after endoscopic mucosal resection of large colorectal polyps: a pilot study. Int J Colorectal Dis 35(11):2141\u20132144. https:\/\/doi.org\/10.1007\/s00384-020-03678-9","journal-title":"Int J Colorectal Dis"},{"issue":"2","key":"13376_CR11","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1016\/j.gie.2019.03.1171","volume":"90","author":"EJ Despott","year":"2019","unstructured":"Despott EJ, May A, Lazaridis N et al (2019) Double-balloon enteroscopy-facilitated cyanoacrylate-injection endotherapy of small-bowel varices: an international experience from 2 European tertiary centers (with videos). Gastrointest Endosc 90(2):302\u2013306. https:\/\/doi.org\/10.1016\/j.gie.2019.03.1171","journal-title":"Gastrointest Endosc"},{"issue":"7","key":"13376_CR12","doi-asserted-by":"publisher","first-page":"4048","DOI":"10.1007\/s00464-021-08480-4","volume":"35","author":"I Bo\u0161koski","year":"2021","unstructured":"Bo\u0161koski I, Hamanaka J, Barbaro F et al (2021) Feasibility and safety of a new endoscopic synthetic sealant nebulizing device over gastric endoscopic submucosal dissections. Surg Endosc 35(7):4048\u20134054. https:\/\/doi.org\/10.1007\/s00464-021-08480-4","journal-title":"Surg Endosc"},{"issue":"48","key":"13376_CR13","doi-asserted-by":"publisher","first-page":"10609","DOI":"10.3748\/wjg.v22.i48.10609","volume":"22","author":"R Grassia","year":"2016","unstructured":"Grassia R, Capone P, Iiritano E et al (2016) Non-variceal upper gastrointestinal bleeding: rescue treatment with a modified cyanoacrylate. World J Gastroenterol 22(48):10609\u201310616. https:\/\/doi.org\/10.3748\/wjg.v22.i48.10609","journal-title":"World J Gastroenterol"},{"issue":"5","key":"13376_CR14","doi-asserted-by":"publisher","first-page":"3155","DOI":"10.1007\/s00464-025-11702-8","volume":"39","author":"Y Ye","year":"2025","unstructured":"Ye Y, Liu L, Xu L (2025) Preliminary exploration of the application of cyanoacrylate glue in Forrest IIa and IIb peptic ulcer hemorrhage. Surg Endosc 39(5):3155\u20133166. https:\/\/doi.org\/10.1007\/s00464-025-11702-8","journal-title":"Surg Endosc"},{"issue":"1","key":"13376_CR15","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.gie.2015.09.035","volume":"83","author":"RD Acosta","year":"2016","unstructured":"Acosta RD, Abraham NS, Chandrasekhara V et al (2016) The management of antithrombotic agents for patients undergoing GI endoscopy. Gastrointest Endosc 83(1):3\u201316. https:\/\/doi.org\/10.1016\/j.gie.2015.09.035","journal-title":"Gastrointest Endosc"},{"issue":"6 Suppl","key":"13376_CR16","doi-asserted-by":"publisher","first-page":"S3","DOI":"10.1016\/s0016-5107(03)02159-x","volume":"58","author":"The Paris endoscopic classification of superficial neoplastic lesions: esophagus, stomach, and colon: November 30 to December 1, 2002","year":"2003","unstructured":"The Paris endoscopic classification of superficial neoplastic lesions: esophagus, stomach, and colon: November 30 to December 1, 2002 (2003) Gastrointest Endosc 58(6 Suppl):S3-43. https:\/\/doi.org\/10.1016\/s0016-5107(03)02159-x","journal-title":"Gastrointest Endosc"},{"issue":"Suppl 1","key":"13376_CR17","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1111\/j.1443-1661.2012.01376.x","volume":"25","author":"I Oda","year":"2013","unstructured":"Oda I, Suzuki H, Nonaka S et al (2013) Complications of gastric endoscopic submucosal dissection. Dig Endosc 25(Suppl 1):71\u201378. https:\/\/doi.org\/10.1111\/j.1443-1661.2012.01376.x","journal-title":"Dig Endosc"},{"issue":"8","key":"13376_CR18","doi-asserted-by":"publisher","first-page":"6255","DOI":"10.1007\/s00464-023-10106-w","volume":"37","author":"L Liu","year":"2023","unstructured":"Liu L, Han M, Shi D et al (2023) Development and validation of a preoperative difficulty scoring system for endoscopic resection of gastric gastrointestinal stromal tumor: a multi-center study. Surg Endosc 37(8):6255\u20136266. https:\/\/doi.org\/10.1007\/s00464-023-10106-w","journal-title":"Surg Endosc"},{"issue":"6","key":"13376_CR19","doi-asserted-by":"publisher","first-page":"1311","DOI":"10.1016\/j.gie.2014.12.010","volume":"81","author":"JT Maple","year":"2015","unstructured":"Maple JT, Abu Dayyeh BK, Chauhan SS et al (2015) Endoscopic submucosal dissection. Gastrointest Endosc 81(6):1311\u20131325. https:\/\/doi.org\/10.1016\/j.gie.2014.12.010","journal-title":"Gastrointest Endosc"},{"issue":"7","key":"13376_CR20","doi-asserted-by":"publisher","first-page":"1358","DOI":"10.1111\/jgh.16545","volume":"39","author":"T Mimura","year":"2024","unstructured":"Mimura T, Yamamoto Y, Suzuki H et al (2024) Risk factors for intraoperative and delayed perforation related with gastric endoscopic submucosal dissection. J Gastroenterol Hepatol 39(7):1358\u20131366. https:\/\/doi.org\/10.1111\/jgh.16545","journal-title":"J Gastroenterol Hepatol"},{"issue":"3","key":"13376_CR21","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1136\/gutjnl-2019-319926","volume":"70","author":"W Hatta","year":"2021","unstructured":"Hatta W, Tsuji Y, Yoshio T et al (2021) Prediction model of bleeding after endoscopic submucosal dissection for early gastric cancer: BEST-J score. Gut 70(3):476\u2013484. https:\/\/doi.org\/10.1136\/gutjnl-2019-319926","journal-title":"Gut"},{"issue":"10","key":"13376_CR22","doi-asserted-by":"publisher","first-page":"994","DOI":"10.1055\/a-1312-9420","volume":"53","author":"DH Jung","year":"2021","unstructured":"Jung DH, Moon HS, Park CH et al (2021) Polysaccharide hemostatic powder to prevent bleeding after endoscopic submucosal dissection in high risk patients: a randomized controlled trial. Endoscopy 53(10):994\u20131002. https:\/\/doi.org\/10.1055\/a-1312-9420","journal-title":"Endoscopy"},{"issue":"1","key":"13376_CR23","doi-asserted-by":"publisher","DOI":"10.1002\/deo2.70299","volume":"6","author":"H Yodying","year":"2026","unstructured":"Yodying H, Viriyaroj V, Rookkachart T et al (2026) Prophylactic mechanical closure for preventing delayed bleeding after gastric endoscopic submucosal dissection: a systematic review and meta-analysis. DEN Open 6(1):e70299. https:\/\/doi.org\/10.1002\/deo2.70299","journal-title":"DEN Open"},{"issue":"9","key":"13376_CR24","doi-asserted-by":"publisher","DOI":"10.4240\/wjgs.v17.i9.109159","volume":"17","author":"SY Xu","year":"2025","unstructured":"Xu SY, Lou QF, Yu AY et al (2025) Meta-analysis of predictive factors for delayed hemorrhage after endoscopic submucosal dissection in early-stage gastric carcinoma. World J Gastrointest Surg 17(9):109159. https:\/\/doi.org\/10.4240\/wjgs.v17.i9.109159","journal-title":"World J Gastrointest Surg"},{"key":"13376_CR25","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000003928","author":"N Uedo","year":"2026","unstructured":"Uedo N, Gotoda T, Takizawa K et al (2026) Low-dose aspirin continuation during gastric endoscopic submucosal dissection in patients with low thrombotic risk: a randomized trial. Am J Gastroenterol. https:\/\/doi.org\/10.14309\/ajg.0000000000003928","journal-title":"Am J Gastroenterol"},{"key":"13376_CR26","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-026-09715-x","author":"Y Huang","year":"2026","unstructured":"Huang Y, Liao F, Pan X et al (2026) Safety of early diet after endoscopic full-thickness resection of gastric tumor: a propensity match analysis. Dig Dis Sci. https:\/\/doi.org\/10.1007\/s10620-026-09715-x","journal-title":"Dig Dis Sci"},{"issue":"2","key":"13376_CR27","doi-asserted-by":"publisher","first-page":"1182","DOI":"10.1007\/s00464-025-12324-w","volume":"40","author":"G Liu","year":"2026","unstructured":"Liu G, Guo X, Yu H et al (2026) Effectiveness of the aspiration method in preventing delayed bleeding after gastric endoscopic submucosal dissection. Surg Endosc 40(2):1182\u20131190. https:\/\/doi.org\/10.1007\/s00464-025-12324-w","journal-title":"Surg Endosc"},{"issue":"1","key":"13376_CR28","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-026-38423-9","volume":"16","author":"S Uehara","year":"2026","unstructured":"Uehara S, Sasaki F, Maeda H et al (2026) Sprayable gelatin microparticles prevent delayed gastric bleeding in an anticoagulated swine model. Sci Rep 16(1):7075. https:\/\/doi.org\/10.1038\/s41598-026-38423-9","journal-title":"Sci Rep"},{"issue":"1","key":"13376_CR29","doi-asserted-by":"publisher","DOI":"10.1186\/s40001-025-03415-4","volume":"30","author":"M Chen","year":"2025","unstructured":"Chen M, Xu L, Lu Q et al (2025) Efficacy of human-derived fibrin sealant in preventing postoperative adverse events after gastric endoscopic submucosal dissection: a retrospective multicenter study. Eur J Med Res 30(1):1162. https:\/\/doi.org\/10.1186\/s40001-025-03415-4","journal-title":"Eur J Med Res"},{"issue":"1","key":"13376_CR30","doi-asserted-by":"publisher","DOI":"10.1080\/07853890.2025.2563749","volume":"57","author":"D Zhang","year":"2025","unstructured":"Zhang D, Han L, Jin R et al (2025) Stratified and propensity score matching analysis of the effectiveness of fibrin glue in preventing postoperative bleeding after endoscopic submucosal dissection. Ann Med 57(1):2563749. https:\/\/doi.org\/10.1080\/07853890.2025.2563749","journal-title":"Ann Med"},{"issue":"2","key":"13376_CR31","doi-asserted-by":"publisher","first-page":"1549","DOI":"10.1007\/s00464-025-12374-0","volume":"40","author":"I Tachec\u00ed","year":"2026","unstructured":"Tachec\u00ed I, \u0160embera \u0160, Zimandlov\u00e1 D et al (2026) Potential role of a synthetic peptide hydrogel in accelerating mucosal defect healing: evidence from a porcine model. Surg Endosc 40(2):1549\u20131558. https:\/\/doi.org\/10.1007\/s00464-025-12374-0","journal-title":"Surg Endosc"},{"key":"13376_CR32","doi-asserted-by":"publisher","DOI":"10.1177\/17562848251386760","volume":"18","author":"S Mukai","year":"2025","unstructured":"Mukai S, Okimoto K, Matsumura T et al (2025) Comparison of the preventive effects of proton pump inhibitors and vonoprazan on delayed bleeding after gastric endoscopic submucosal dissection. Ther Adv Gastroenterol 18:17562848251386760. https:\/\/doi.org\/10.1177\/17562848251386760","journal-title":"Ther Adv Gastroenterol"},{"issue":"1","key":"13376_CR33","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1186\/s12876-025-04575-7","volume":"26","author":"L Zou","year":"2026","unstructured":"Zou L, Yang Y, Shi J et al (2026) Validation of the BEST-J score and identification of bile reflux as a risk factor for delayed bleeding after gastric endoscopic submucosal dissection. BMC Gastroenterol 26(1):95. https:\/\/doi.org\/10.1186\/s12876-025-04575-7","journal-title":"BMC Gastroenterol"},{"key":"13376_CR34","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-026-12666-z","author":"K Gu","year":"2026","unstructured":"Gu K, Gu T, Xie W et al (2026) Prediction of delayed bleeding after endoscopic submucosal dissection in early gastric cancer and precancerous lesions by BEST-C score. Surg Endosc. https:\/\/doi.org\/10.1007\/s00464-026-12666-z","journal-title":"Surg Endosc"},{"issue":"2","key":"13376_CR35","doi-asserted-by":"publisher","first-page":"1116","DOI":"10.1007\/s00464-025-12361-5","volume":"40","author":"T Yoshikawa","year":"2026","unstructured":"Yoshikawa T, Utsumi T, Inoue T et al (2026) Factors associated with adverse events and three-year survival following endoscopic submucosal dissection for early gastric cancer in patients aged 85 years or older. Surg Endosc 40(2):1116\u20131127. https:\/\/doi.org\/10.1007\/s00464-025-12361-5","journal-title":"Surg Endosc"},{"issue":"12","key":"13376_CR36","doi-asserted-by":"publisher","first-page":"8418","DOI":"10.1007\/s00464-025-12201-6","volume":"39","author":"JY Park","year":"2025","unstructured":"Park JY, Kim MS, Kim BJ et al (2025) Analysis of risk factors for bleeding after gastric endoscopic submucosal dissection with an emphasis on age and sex differences: a nationwide population-based study. Surg Endosc 39(12):8418\u20138431. https:\/\/doi.org\/10.1007\/s00464-025-12201-6","journal-title":"Surg Endosc"},{"key":"13376_CR37","doi-asserted-by":"publisher","DOI":"10.1055\/a-2778-7997","volume":"14","author":"M Moreno-Sanchez","year":"2026","unstructured":"Moreno-Sanchez M, Herreros de Tejada A, Fern\u00e1ndez-Esparrach G et al (2026) Endoscopic submucosal dissection for early gastric cancer in the elderly: Spanish multicenter prospective study during initial experience. Endosc Int Open 14:a27787997. https:\/\/doi.org\/10.1055\/a-2778-7997","journal-title":"Endosc Int Open"},{"key":"13376_CR38","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-026-12655-2","author":"Q Zhang","year":"2026","unstructured":"Zhang Q, Yi L, Zhou Y, Wang Y, Huang S (2026) The efficacy and safety of traction-assisted endoscopic submucosal resection in early gastric cancer: a systematic review and meta-analysis. Surg Endosc. https:\/\/doi.org\/10.1007\/s00464-026-12655-2","journal-title":"Surg Endosc"}],"container-title":["Surgical Endoscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00464-026-13376-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00464-026-13376-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00464-026-13376-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T18:41:26Z","timestamp":1789584086000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00464-026-13376-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,16]]},"references-count":38,"alternative-id":["13376"],"URL":"https:\/\/doi.org\/10.1007\/s00464-026-13376-2","relation":{},"ISSN":["0930-2794","1432-2218"],"issn-type":[{"value":"0930-2794","type":"print"},{"value":"1432-2218","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,16]]},"assertion":[{"value":"12 March 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 September 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 September 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Fengcheng Zang, Yunfu Feng, Bin He, Chao Ma, Jian Chen, Luojie Liu, and Xiaodan Xu have no conflicts of interest or financial ties to disclose.","order":1,"name":"Ethics","label":"Disclosures","group":{"name":"EthicsHeading","label":"Declarations"}}]}}