{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T04:04:04Z","timestamp":1791086644408,"version":"4.1.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2005,1,27]],"date-time":"2005-01-27T00:00:00Z","timestamp":1106784000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Nephrol"],"published-print":{"date-parts":[[2005,3]]},"DOI":"10.1007\/s00467-004-1689-4","type":"journal-article","created":{"date-parts":[[2005,1,30]],"date-time":"2005-01-30T15:53:30Z","timestamp":1107100410000},"page":"319-322","source":"Crossref","is-referenced-by-count":32,"title":["Impact of growth plate senescence on catch-up growth and epiphyseal fusion"],"prefix":"10.1007","volume":"20","author":[{"given":"Ola","family":"Nilsson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Baron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2005,1,27]]},"reference":[{"key":"CR1","unstructured":"National Center for Health Statistics (2000) NHANES III References and Reports. Centers for Disease Control and Prevention. Available at http:\/\/www.cdc.gov\/growthcharts\/"},{"key":"CR2","unstructured":"Valdes-Dapena M, Kalousek DK, Huff DS (1975) Rate of antenatal growth. In: Potter EL, Craig JM (eds) Pathology of the fetus and the infant. Year Book Medical, Chicago, pp 18?22"},{"key":"CR3","first-page":"349","volume":"106","author":"Hughes","year":"1970","unstructured":"Hughes PC, Tanner JM (1970) A longitudinal study of the growth of the black-hooded rat: methods of measurement and rates of growth for skull, limbs, pelvis, nose-rump and tail lengths. J Anat 106:349?370","journal-title":"J Anat"},{"key":"CR4","first-page":"409","volume":"5","author":"Walker","year":"1972","unstructured":"Walker KV, Kember NF (1972) Cell kinetics of growth cartilage in the rat tibia. II. Measurements during ageing. Cell Tissue Kinet 5:409?419","journal-title":"Cell Tissue Kinet"},{"key":"CR5","first-page":"288","volume":"95","author":"Kember","year":"1973","unstructured":"Kember NF (1973) Aspects of the maturation process in growth cartilage in the rat tibia. Clin Orthop 95:288?294","journal-title":"Clin Orthop"},{"key":"CR6","doi-asserted-by":"crossref","first-page":"6871","DOI":"10.1073\/pnas.121180498","volume":"98","author":"Weise","year":"2001","unstructured":"Weise M, De-Levi S, Barnes KM, Gafni RI, Abad V, Baron J (2001) Effects of estrogen on growth plate senescence and epiphyseal fusion. Proc Natl Acad Sci USA 98:6871?6876","journal-title":"Proc Natl Acad Sci USA"},{"key":"CR7","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1385\/ENDO:18:3:271","volume":"18","author":"Chrysis","year":"2002","unstructured":"Chrysis D, Nilsson O, Ritzen EM, Savendahl L (2002) Apoptosis is developmentally regulated in rat growth plate. Endocrine 18:271?278","journal-title":"Endocrine"},{"key":"CR8","first-page":"398","volume":"19","author":"Stevens","year":"1999","unstructured":"Stevens DG, Boyer MI, Bowen CV (1999) Transplantation of epiphyseal plate allografts between animals of different ages. J Pediatr Orthop 19:398?403","journal-title":"J Pediatr Orthop"},{"key":"CR9","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1203\/00006450-200111000-00014","volume":"50","author":"Gafni","year":"2001","unstructured":"Gafni RI, Weise M, Robrecht DT, Meyers JL, Barnes KM, De Levi S, Baron J (2001) Catch-up growth is associated with delayed senescence of the growth plate in rabbits. Pediatr Res 50:618?623","journal-title":"Pediatr Res"},{"key":"CR10","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1210\/endo.135.4.7925098","volume":"135","author":"Baron","year":"1994","unstructured":"Baron J, Klein KO, Colli MJ, Yanovski JA, Novosad JA, Bacher JD, Cutler GB Jr (1994) Catch-up growth after glucocorticoid excess: a mechanism intrinsic to the growth plate. Endocrinology 135:1367?1371","journal-title":"Endocrinology"},{"key":"CR11","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1006\/excr.1999.4665","volume":"253","author":"Wei","year":"1999","unstructured":"Wei W, Sedivy JM (1999) Differentiation between senescence (M1) and crisis (M2) in human fibroblast cultures. Exp Cell Res 253:519?522","journal-title":"Exp Cell Res"},{"key":"CR12","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/S0022-3476(63)80035-9","volume":"62","author":"Prader","year":"1963","unstructured":"Prader A, Tanner JM, Harnack G von (1963) Catch-up growth following illness or starvation. An example of developmental canalization in man. J Pediatr 62:646?659","journal-title":"J Pediatr"},{"key":"CR13","first-page":"817","volume":"34","author":"Tanner","year":"1963","unstructured":"Tanner JM (1963) The regulation of human growth. Child Dev 34:817?847","journal-title":"Child Dev"},{"key":"CR14","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0960-0760(97)80005-2","volume":"61","author":"Cutler","year":"1997","unstructured":"Cutler GB Jr (1997) The role of estrogen in bone growth and maturation during childhood and adolescence. J Steroid Biochem Mol Biol 61:141?144","journal-title":"J Steroid Biochem Mol Biol"},{"key":"CR15","unstructured":"Veldhuis JD, Bowers CY (2003) Three-peptide control of pulsatile and entropic feedback-sensitive modes of growth hormone secretion: modulation by estrogen and aromatizable androgen. J Pediatr Endocrinol Metab 16 [Suppl] 3:587?605"},{"key":"CR16","first-page":"996","volume":"76","author":"Keenan","year":"1993","unstructured":"Keenan BS, Richards GE, Ponder SW, Dallas JS, Nagamani M, Smith ER (1993) Androgen-stimulated pubertal growth: the effects of testosterone and dihydrotestosterone on growth hormone and insulin-like growth factor-I in the treatment of short stature and delayed puberty. J Clin Endocrinol Metab 76:996?1001","journal-title":"J Clin Endocrinol Metab"},{"key":"CR17","first-page":"635","volume":"81","author":"Nilsson","year":"1996","unstructured":"Nilsson KO, Albertsson-Wikland K, Alm J, Aronson S, Gustafsson J, Hagenas L, Hager A, Ivarsson SA, Karlberg J, Kristrom B, Marcus C, Moell C, Ritzen M, Tuvemo T, Wattsgard C, Westgren U, Westphal O, Aman J (1996) Improved final height in girls with Turner?s syndrome treated with growth hormone and oxandrolone. J Clin Endocrinol Metab 81:635?640","journal-title":"J Clin Endocrinol Metab"},{"key":"CR18","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1136\/adc.63.5.501","volume":"63","author":"Stanhope","year":"1988","unstructured":"Stanhope R, Buchanan CR, Fenn GC, Preece MA (1988) Double blind placebo controlled trial of low dose oxandrolone in the treatment of boys with constitutional delay of growth and puberty. Arch Dis Child 63:501?505","journal-title":"Arch Dis Child"},{"key":"CR19","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1210\/en.2002-221108","volume":"144","author":"Nilsson","year":"2003","unstructured":"Nilsson O, Falk J, Ritzen EM, Baron J, Savendahl L (2003) Raloxifene acts as an estrogen agonist on the rabbit growth plate. Endocrinology 144:1481?1485","journal-title":"Endocrinology"},{"key":"CR20","first-page":"4677","volume":"84","author":"Grumbach","year":"1999","unstructured":"Grumbach MM, Auchus RJ (1999) Estrogen: consequences and implications of human mutations in synthesis and action. J Clin Endocrinol Metab 84:4677?4694","journal-title":"J Clin Endocrinol Metab"},{"key":"CR21","first-page":"3689","volume":"80","author":"Morishima","year":"1995","unstructured":"Morishima A, Grumbach MM, Simpson ER, Fisher C, Qin K (1995) Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens. J Clin Endocrinol Metab 80:3689?3698","journal-title":"J Clin Endocrinol Metab"},{"key":"CR22","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1056\/NEJM199410203311604","volume":"331","author":"Smith","year":"1994","unstructured":"Smith EP, Boyd J, Frank GR, Takahashi H, Cohen RM, Specker B, Williams TC, Lubahn DB, Korach KS (1994) Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man. N Engl J Med 331:1056?1061","journal-title":"N Engl J Med"},{"key":"CR23","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1002\/aja.1000690206","volume":"69","author":"Silberberg","year":"1941","unstructured":"Silberberg M, Silberberg R (1941) Further investigations concerning the influence of estrogen on skeletal tissues. Am J Anat 69:295?325","journal-title":"Am J Anat"},{"key":"CR24","doi-asserted-by":"crossref","first-page":"151","DOI":"10.3181\/00379727-44-11385","volume":"44","author":"Sutro","year":"1940","unstructured":"Sutro CJ (1940) Effects of subcutaneous injection of estrogen upon skeleton in immature mice. Proc Soc Exp Biol Med 44:151?154","journal-title":"Proc Soc Exp Biol Med"},{"key":"CR25","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1001\/archpedi.1968.02100010311003","volume":"115","author":"Sigurjonsdottir","year":"1968","unstructured":"Sigurjonsdottir TJ, Hayles AB (1968) Precocious puberty. A report of 96 cases. Am J Dis Child 115:309?321","journal-title":"Am J Dis Child"},{"key":"CR26","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1056\/NEJM199808273390905","volume":"339","author":"Bilezikian","year":"1998","unstructured":"Bilezikian JP, Morishima A, Bell J, Grumbach MM (1998) Increased bone mass as a result of estrogen therapy in a man with aromatase deficiency. N Engl J Med 339:599?603","journal-title":"N Engl J Med"},{"key":"CR27","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1056\/NEJM199707103370204","volume":"337","author":"Carani","year":"1997","unstructured":"Carani C, Qin K, Simoni M, Faustini-Fustini M, Serpente S, Boyd J, Korach KS, Simpson ER (1997) Effect of testosterone and estradiol in a man with aromatase deficiency. N Engl J Med 337:91?95","journal-title":"N Engl J Med"}],"container-title":["Pediatric Nephrology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-004-1689-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00467-004-1689-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-004-1689-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T00:39:23Z","timestamp":1559090363000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00467-004-1689-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1,27]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005,3]]}},"alternative-id":["1689"],"URL":"https:\/\/doi.org\/10.1007\/s00467-004-1689-4","relation":{},"ISSN":["0931-041X","1432-198X"],"issn-type":[{"value":"0931-041X","type":"print"},{"value":"1432-198X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,1,27]]}}}