{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T18:27:38Z","timestamp":1694629658755},"reference-count":86,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2007,9,1]],"date-time":"2007-09-01T00:00:00Z","timestamp":1188604800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Nephrol"],"published-print":{"date-parts":[[2007,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Growth failure is a common and significant clinical problem for children on dialysis and often remains a major impediment to their rehabilitation. Early referral to a paediatric nephrology centre and appropriate management before the initiation of dialysis may significantly prevent growth deterioration. Growth in children on dialysis can be affected by nutritional, metabolic, and hormonal changes. Early diagnosis of malnutrition and aggressive management should be a priority. Gastrostomy feeding should be used when adequate oral intake to maintain normal height and weight velocity cannot be achieved. Active vitamin\u00a0D metabolites should be used carefully, to prevent low-turnover bone disease. All children should have an adequate regimen of dialysis and an appropriate management of malnutrition, renal osteodystrophy, metabolic acidosis, salt wasting and anaemia, before recombinant human growth hormone (rhGH) administration is considered. The current challenge of reversing growth impairment in children on dialysis can only be achieved by optimization of their care.<\/jats:p>","DOI":"10.1007\/s00467-007-0481-7","type":"journal-article","created":{"date-parts":[[2007,3,30]],"date-time":"2007-03-30T12:02:45Z","timestamp":1175256165000},"page":"1251-1259","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Growth of prepubertal children on dialysis"],"prefix":"10.1007","volume":"22","author":[{"given":"Constantinos J.","family":"Stefanidis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00fcnter","family":"Klaus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2007,9,1]]},"reference":[{"key":"481_CR1","first-page":"133","volume":"9","author":"C Kleinknecht","year":"1980","unstructured":"Kleinknecht C, Broyer M, Gagnadoux MF, Martihenneberg C, Dartois AM, Kermanach C, Pouliquen M, Degoulet P, Usberti M, Roy MP (1980) Growth in children treated with long-term dialysis. A study of 76 patients. Adv Nephrol Necker Hosp 9:133\u2013163","journal-title":"Adv Nephrol Necker Hosp"},{"key":"481_CR2","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1016\/S0022-3476(83)80233-9","volume":"102","author":"CJ Stefanidis","year":"1983","unstructured":"Stefanidis CJ, Hewitt IK, Balfe JW (1983) Growth in children receiving continuous ambulatory peritoneal dialysis. J Pediatr 102:681\u2013685","journal-title":"J Pediatr"},{"key":"481_CR3","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1007\/s00467-002-0838-x","volume":"17","author":"SL Furth","year":"2002","unstructured":"Furth SL, Hwang W, Yang C, Neu AM, Fivush BA, Powe NR (2002) Growth failure, risk of hospitalization and death for children with end-stage renal disease. Pediatr Nephrol 17:450\u2013455","journal-title":"Pediatr Nephrol"},{"key":"481_CR4","first-page":"55","volume":"23","author":"G Rizzoni","year":"1986","unstructured":"Rizzoni G, Broyer M, Brunner FP, Brynger H, Challah S, Kramer P, Oules R, Selwood NH, Wing AJ, Balas EA (1986) Combined report on regular dialysis and transplantation of children in Europe, XIII, 1983. Proc Eur Dial Transplant Assoc Eur Ren Assoc 23:55\u201383","journal-title":"Proc Eur Dial Transplant Assoc Eur Ren Assoc"},{"key":"481_CR5","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1001\/archpedi.1997.02170470051010","volume":"151","author":"GD Zimet","year":"1997","unstructured":"Zimet GD, Owens R, Dahms W, Cutler M, Litvene M, Cuttler L (1997) Psychosocial outcome of children evaluated for short stature. Arch Pediatr Adolesc Med 151:1017\u20131023","journal-title":"Arch Pediatr Adolesc Med"},{"issue":"9","key":"481_CR6","doi-asserted-by":"publisher","first-page":"1349","DOI":"10.1007\/s00467-006-0348-3","volume":"22","author":"Janette Cansick","year":"2006","unstructured":"Cansick J, Waller S, Ridout D, Rees L (2006) Growth and PTH in prepubertal children on long-term dialysis. Pediatr Nephrol DOI https:\/\/doi.org\/10.1007\/s00467-006-0348-3","journal-title":"Pediatric Nephrology"},{"key":"481_CR7","first-page":"215","volume-title":"Kidney disorders in children and adolescents","author":"CJ Stefanidis","year":"2006","unstructured":"Stefanidis CJ (2006) Nutritional and growth aspects of the care of children with kidney disease. In: Hogg R (ed) Kidney disorders in children and adolescents. Taylor & Francis, Oxford, pp 215\u2013223"},{"issue":"Suppl 3","key":"481_CR8","doi-asserted-by":"publisher","first-page":"S179","DOI":"10.1177\/089686080102103S30","volume":"21","author":"V Chadha","year":"2001","unstructured":"Chadha V, Blowey DL, Warady BA (2001) Is growth a valid outcome measure of dialysis clearance in children undergoing peritoneal dialysis? Perit Dial Int 21(Suppl 3):S179\u2013S184","journal-title":"Perit Dial Int"},{"key":"481_CR9","first-page":"1455","volume":"133","author":"F Cano","year":"2005","unstructured":"Cano F, Azocar PM, Marin V, Rodriguez E, Delucchi A, Ratner R, Cavada G (2005) Dialysis dose, nutrition and growth among pediatric patients on peritoneal dialysis. Rev Med Chil 133:1455\u20131464","journal-title":"Rev Med Chil"},{"key":"481_CR10","unstructured":"North American Pediatric Renal Transplant Cooperative Study (2006) Annual report. Renal transplantation, dialysis, chronic renal insufficiency. Available at: https:\/\/doi.org\/web.emmes.com\/study\/ped\/annlrept\/annlrept2006.pdf"},{"key":"481_CR11","doi-asserted-by":"publisher","first-page":"2175","DOI":"10.1093\/ndt\/gfh409","volume":"19","author":"RM Huisman","year":"2004","unstructured":"Huisman RM (2004) The deadly risk of late referral. Nephrol Dial Transplant 19:2175\u20132180","journal-title":"Nephrol Dial Transplant"},{"key":"481_CR12","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1046\/j.1523-1755.61.s80.6.x","volume":"61","author":"N Lameire","year":"2002","unstructured":"Lameire N, Wauters JP, Teruel J, Van Biesen W, Vanholder R (2002) An update on the referral pattern of patients with end-stage renal disease. Kidney Int 61:27\u201334","journal-title":"Kidney Int"},{"key":"481_CR13","doi-asserted-by":"publisher","first-page":"1808","DOI":"10.1093\/ndt\/gfg573","volume":"19","author":"WH Kazmi","year":"2004","unstructured":"Kazmi WH, Obrador GT, Khan SS, Pereira BJ, Kausz AT (2004) Late nephrology referral and mortality among patients with end-stage renal disease: a propensity score analysis. Nephrol Dial Transplant 19:1808\u20131814","journal-title":"Nephrol Dial Transplant"},{"key":"481_CR14","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1093\/ndt\/gfi313","volume":"21","author":"A Jander","year":"2006","unstructured":"Jander A, Nowicki M, Tkaczyk M, Roszkowska-Blaim M, Jarmolinski T, Marczak E, Paluba E, Pietrzyk JA, Siten G, Stankiewicz R, Szprynger K, Zajaczkowska M, Zachwieja J, Zoch-Zwierz W, Zwolinska D (2006) Does a late referral to a nephrologist constitute a problem in children starting renal replacement therapy in Poland? A nationwide study. Nephrol Dial Transplant 21:957\u2013961","journal-title":"Nephrol Dial Transplant"},{"key":"481_CR15","doi-asserted-by":"publisher","first-page":"1899","DOI":"10.1681\/ASN.V9101899","volume":"9","author":"D Haffner","year":"1998","unstructured":"Haffner D, Wuhl E, Schaefer F, Nissel R, Tonshoff B, Mehls O (1998) Factors predictive of the short- and long-term efficacy of growth hormone treatment in prepubertal children with chronic renal failure. German Study Group for growth hormone treatment in children with chronic renal failure. J Am Soc Nephrol 9:1899\u20131907","journal-title":"J Am Soc Nephrol"},{"key":"481_CR16","first-page":"S15","volume":"30","author":"H Trachtman","year":"1986","unstructured":"Trachtman H, Hackney P, Tejani A (1986) Pediatric hemodialysis: a decade\u2019s (1974\u20131984) perspective. Kidney Int 30:S15\u2013S22","journal-title":"Kidney Int"},{"key":"481_CR17","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1016\/S0022-3476(99)70205-2","volume":"134","author":"A Tom","year":"1999","unstructured":"Tom A, McCauley L, Bell L, Rodd C, Espinosa P, Yu G, Yu J, Girardin C, Sharma A (1999) Growth during maintenance hemodialysis: impact of enhanced nutrition and clearance. J Pediatr 134:464\u2013471","journal-title":"J Pediatr"},{"key":"481_CR18","doi-asserted-by":"publisher","first-page":"1746","DOI":"10.1007\/s00467-006-0226-z","volume":"21","author":"M Fischbach","year":"2006","unstructured":"Fischbach M, Terzic J, Menouer S, Dheu C, Soskin S, Helmstetter A, Burger MC (2006) Intensified and daily hemodialysis in children might improve statural growth. Pediatr Nephrol 21:1746\u20131752","journal-title":"Pediatr Nephrol"},{"key":"481_CR19","first-page":"S11","volume":"19","author":"DE Potter","year":"1986","unstructured":"Potter DE, San Luis E, Wipfler JE, Portale AA (1986) Comparison of continuous ambulatory peritoneal dialysis and hemodialysis in children. Kidney Int Suppl 19:S11\u2013S14","journal-title":"Kidney Int Suppl"},{"key":"481_CR20","doi-asserted-by":"publisher","first-page":"1786","DOI":"10.1681\/ASN.V1081786","volume":"10","author":"F Schaefer","year":"1999","unstructured":"Schaefer F, Klaus G, Mehls O (1999) Peritoneal transport properties and dialysis dose affect growth and nutritional status in children on chronic peritoneal dialysis. J Am Soc Nephrol 10:1786\u20131792","journal-title":"J Am Soc Nephrol"},{"key":"481_CR21","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1093\/ndt\/17.3.380","volume":"17","author":"M Fischbach","year":"2002","unstructured":"Fischbach M, Stefanidis CJ, Watson AR; European Paediatric Peritoneal Dialysis Working Group (2002) Guidelines by an ad hoc European committee on adequacy of paediatric peritoneal dialysis prescription. Nephrol Dial Transplant 17:380\u2013385","journal-title":"Nephrol Dial Transplant"},{"key":"481_CR22","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1007\/PL00013417","volume":"14","author":"T Holtta","year":"2000","unstructured":"Holtta T, Ronnholm K, Jalanko H, Holmberg C (2000) Clinical outcome of pediatric patients on peritoneal dialysis under adequacy control. Pediatr Nephrol 14:889\u2013897","journal-title":"Pediatr Nephrol"},{"issue":"Suppl 1","key":"481_CR23","first-page":"S89","volume":"20","author":"L McCauley","year":"2000","unstructured":"McCauley L, Champoux S, Parvex P, Rodd C, Sharma A, Tom A, Bell L (2000) Enhanced growth in children on peritoneal dialysis (PD): dialysis dose, nutrition, and metabolic control. Perit Dial Int 20(Suppl 1):S89","journal-title":"Perit Dial Int"},{"key":"481_CR24","first-page":"1620","volume":"21","author":"CJ Stefanidis","year":"2006","unstructured":"Stefanidis CJ, Mitsioni A, Askiti V, Siomou E, Siapera D (2006) The importance of residual renal function in children on chronic peritoneal dialysis. Pediatr Nephrol 21:1620 (abstract)","journal-title":"Pediatr Nephrol"},{"key":"481_CR25","first-page":"397","volume":"10","author":"J Rottembourg","year":"1982","unstructured":"Rottembourg J, Issad B, Gallego JL, Degoulet P, Aime F, Gueffaf B, Legrain M (1982) Evolution of residual renal function in patients undergoing maintenance hemodialysis or continuous ambulatory peritoneal dialysis. Proc Eur Dial Transplant Assoc 10:397\u2013403","journal-title":"Proc Eur Dial Transplant Assoc"},{"key":"481_CR26","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1007\/BF00858132","volume":"8","author":"J Feber","year":"1994","unstructured":"Feber J, Scharer K, Schaefer F, Mikova M, Janda J (1994) Residual renal function in children on hemodialysis and peritoneal dialysis therapy. Pediatr Nephrol 8:579\u2013583","journal-title":"Pediatr Nephrol"},{"key":"481_CR27","doi-asserted-by":"publisher","first-page":"858","DOI":"10.1007\/s004670100687","volume":"16","author":"E Erkan","year":"2001","unstructured":"Erkan E, Moritz M, Kaskel F (2001) Impact of residual renal function in children on hemodialysis. Pediatr Nephrol 16:858\u2013861","journal-title":"Pediatr Nephrol"},{"key":"481_CR28","first-page":"169","volume":"2","author":"PH Brown","year":"1988","unstructured":"Brown PH, Kalra PA, Turney JH, Cooper EH (1988) Serum low-molecular-weight proteins in hemodialysis patients: effect of residual renal function. Nephrol Dial Transplant 2:169\u2013173","journal-title":"Nephrol Dial Transplant"},{"key":"481_CR29","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1093\/ajcn\/38.4.599","volume":"38","author":"I Salusky","year":"1983","unstructured":"Salusky I, Fine R, Nelson P, Blumenkrantz M, Kopple J (1983) Nutritional status in children undergoing continuous ambulatory peritoneal dialysis. Am J Clin Nutr 38:599\u2013611","journal-title":"Am J Clin Nutr"},{"key":"481_CR30","first-page":"345","volume":"S16","author":"CJ Stefanidis","year":"1983","unstructured":"Stefanidis CJ, Hanning R, Cherian G, Hewitt IK, Balfe JW (1983) Nutritional aspects of continuous ambulatory peritoneal dialysis in children. Kidney Int S16:345","journal-title":"Kidney Int"},{"key":"481_CR31","doi-asserted-by":"publisher","first-page":"1946","DOI":"10.1093\/ndt\/gfl094","volume":"21","author":"A Edefonti","year":"2006","unstructured":"Edefonti A, Paglialonga F, Picca M, Perfumo F, Verrina E, Lavoratti G, Rinaldi S, Rizzoni G, Zacchello G, Ciofani A, Sorino P, Loi S, Grassi M (2006) A prospective multicentre study of the nutritional status in children on chronic peritoneal dialysis. Nephrol Dial Transplant 21:1946\u20131951","journal-title":"Nephrol Dial Transplant"},{"key":"481_CR32","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1177\/089686080302300607","volume":"23","author":"M Ekim","year":"2003","unstructured":"Ekim M, Ikinciogullari A, Ulukol B, Bakkaloglu SA, Ozkaya N, Kendirli T, Adiyaman P, Babacan E, Ocal G (2003) Evaluation of nutritional status and factors related to malnutrition in children on CAPD. Perit Dial Int 23:557\u2013562","journal-title":"Perit Dial Int"},{"issue":"Suppl 1","key":"481_CR33","doi-asserted-by":"publisher","first-page":"S561","DOI":"10.1177\/089686089601601S116","volume":"16","author":"C Stefanidis","year":"1996","unstructured":"Stefanidis C, Siapera D, Papadopoulou A, Michelis K (1996) Body composition of children on CAPD. Perit Dial Int 16(Suppl 1):S561\u2013S566","journal-title":"Perit Dial Int"},{"key":"481_CR34","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1007\/s004670000353","volume":"14","author":"F Schaefer","year":"2000","unstructured":"Schaefer F, W\u00fchl E, Feneberg R, Mehls O, Sch\u00e4rer K (2000) Assessment of body composition in children with chronic renal failure. Pediatr Nephrol 14:673\u2013678","journal-title":"Pediatr Nephrol"},{"issue":"4 Suppl 1","key":"481_CR35","doi-asserted-by":"publisher","first-page":"S68","DOI":"10.1053\/ajkd.2001.27578","volume":"38","author":"JD Kopple","year":"2001","unstructured":"Kopple JD; National Kidney Foundation K\/DOQI Work Group (2001) The National Kidney Foundation K\/DOQI clinical practice guidelines for dietary protein intake for chronic dialysis patients. Am J Kidney Dis 38(4 Suppl 1):S68\u2013S73","journal-title":"Am J Kidney Dis"},{"key":"481_CR36","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1046\/j.1523-1755.2002.00169.x","volume":"61","author":"CS Wong","year":"2002","unstructured":"Wong CS, Hingorani S, Gillen DL, Sherrard DJ, Watkins SL, Brandt JR, Ball A, Stehman-Breen CO (2002) Hypoalbuminemia and risk of death in pediatric patients with end-stage renal disease. Kidney Int 61:630\u2013637","journal-title":"Kidney Int"},{"key":"481_CR37","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1007\/s00467-002-0886-2","volume":"17","author":"AS Brem","year":"2002","unstructured":"Brem AS, Lambert C, Hill C, Kitsen J, Shemin DG (2002) Prevalence of protein malnutrition in children maintained on peritoneal dialysis. Pediatr Nephrol 17:527\u2013530","journal-title":"Pediatr Nephrol"},{"key":"481_CR38","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1136\/adc.64.4.573","volume":"64","author":"L Rees","year":"1989","unstructured":"Rees L, Rigden SPA, Ward GM (1989) Chronic renal failure and growth. Arch Dis Child 64:573\u2013577","journal-title":"Arch Dis Child"},{"issue":"Suppl 2","key":"481_CR39","doi-asserted-by":"publisher","first-page":"S251","DOI":"10.1177\/089686089301302S62","volume":"13","author":"C Stefanidis","year":"1993","unstructured":"Stefanidis C, Michelakaki H, Koulieri A, Michelis K (1993) Nutritional status and growth in children less than 12\u00a0kg treated with continuous ambulatory peritoneal dialysis. Perit Dial Int 13(Suppl 2):S251\u2013S253","journal-title":"Perit Dial Int"},{"key":"481_CR40","doi-asserted-by":"publisher","first-page":"1681","DOI":"10.1046\/j.1523-1755.2000.00013.x","volume":"57","author":"JA Kari","year":"2000","unstructured":"Kari JA, Gonzalez C, Ledermann SE, Shaw V, Rees L (2000) Outcome and growth of infants with severe chronic renal failure. Kidney Int 57:1681\u20131687","journal-title":"Kidney Int"},{"key":"481_CR41","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1136\/bmj.1.6058.416","volume":"1","author":"PR Betts","year":"1977","unstructured":"Betts PR, Magrath G, White RHR (1977) Role of dietary energy supplementation in growth of children with chronic renal insufficiency. Br Med J 1:416\u2013420","journal-title":"Br Med J"},{"issue":"Suppl 1","key":"481_CR42","doi-asserted-by":"publisher","first-page":"S521","DOI":"10.1177\/089686089601601S107","volume":"16","author":"BA Warady","year":"1996","unstructured":"Warady BA, Weis L, Johnson L (1996) Nasogastric tube feeding in infants on peritoneal dialysis. Perit Dial Int 16(Suppl 1):S521\u2013S525","journal-title":"Perit Dial Int"},{"key":"481_CR43","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1177\/089686080602600106","volume":"26","author":"AR Watson","year":"2006","unstructured":"Watson AR (2006) Gastrostomy feeding in children on chronic peritoneal dialysis. Perit Dial Int 26:41\u201342","journal-title":"Perit Dial Int"},{"key":"481_CR44","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1007\/s004670050239","volume":"11","author":"L Dello Strologo","year":"1997","unstructured":"Dello Strologo L, Principato F, Sinibaldi D, Appiani AC, Terzi F, Dartois AM, Rizzoni G (1997) Feeding dysfunction in infants with severe chronic renal failure after long-term nasogastric tube feeding. Pediatr Nephrol 11:84\u201386","journal-title":"Pediatr Nephrol"},{"key":"481_CR45","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1177\/089686089901900308","volume":"19","author":"IJ Ramage","year":"1999","unstructured":"Ramage IJ, Geary DF, Harvey E, Secker DJ, Balfe JA, Balfe JW (1999) Efficacy of gastrostomy feeding in infants and older children receiving chronic peritoneal dialysis. Perit Dial Int 19:231\u2013236","journal-title":"Perit Dial Int"},{"key":"481_CR46","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1007\/s00467-002-0846-x","volume":"17","author":"SE Ledermann","year":"2002","unstructured":"Ledermann SE, Spitz L, Moloney J, Rees L, Trompeter RS (2002) Gastrostomy feeding in infants and children on peritoneal dialysis. Pediatr Nephrol 17:246\u2013250","journal-title":"Pediatr Nephrol"},{"key":"481_CR47","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1177\/089686080602600111","volume":"26","author":"C von Schnakenburg","year":"2006","unstructured":"von Schnakenburg C, Feneberg R, Plank C, Zimmering M, Arbeiter K, Bald M, Fehrenbach H, Griebel M, Licht C, Konrad M, Timmermann K, Kemper MJ (2006) Percutaneous endoscopic gastrostomy in children on peritoneal dialysis. Perit Dial Int 26:69\u201377","journal-title":"Perit Dial Int"},{"key":"481_CR48","doi-asserted-by":"publisher","first-page":"S3","DOI":"10.1016\/S0022-3476(96)70182-8","volume":"129","author":"CL Abitbol","year":"1996","unstructured":"Abitbol CL, Chan JCM, Trachtman H, Strauss J, Greifer I (1996) Growth in children with moderate renal insufficiency: measurement, evaluation and treatment. J Pediatr 129:S3\u2013S8","journal-title":"J Pediatr"},{"key":"481_CR49","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1007\/s00467-001-0747-4","volume":"17","author":"AM Wingen","year":"2002","unstructured":"Wingen AM, Mehls O (2002) Nutrition in children with preterminal chronic renal failure. Myth or important therapeutic aid? Pediatr Nephrol 17:111\u2013120","journal-title":"Pediatr Nephrol"},{"key":"481_CR50","doi-asserted-by":"publisher","first-page":"1074","DOI":"10.1681\/ASN.V961074","volume":"9","author":"M Daschner","year":"1998","unstructured":"Daschner M, T\u00f6nshoff B, Blum WF, Englaro P, Wingen A-M, Schaefer F, W\u00fchl E, Rascher W, Mehls O (1998) Inappropriate elevation of serum leptin levels in children with chronic renal failure. European Study Group for nutritional treatment of chronic renal failure in childhood. J Am Soc Nephrol 9:1074\u20131079","journal-title":"J Am Soc Nephrol"},{"key":"481_CR51","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/S0272-6386(86)80068-3","volume":"7","author":"RW Chesney","year":"1986","unstructured":"Chesney RW, Mehls O, Anast CS, Brown E, Hammerman MR, Portale A, Fallon MD, Mahan J Jr, Alfrey AC (1986) Renal osteodystrophy in children: the role of vitamin D, phosphorus, and parathyroid hormone Am. J Kidney Dis 7:275\u2013284","journal-title":"Am J Kidney Dis"},{"key":"481_CR52","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1007\/s00467-005-1821-0","volume":"20","author":"B Tonshoff","year":"2005","unstructured":"Tonshoff B, Kiepe D, Ciarmatori S (2005) Growth hormone\/insulin-like growth factor system in children with chronic renal failure. Pediatr Nephrol 20:279\u2013289","journal-title":"Pediatr Nephrol"},{"key":"481_CR53","first-page":"S48","volume":"29","author":"HH Malluche","year":"1990","unstructured":"Malluche HH, Faugere MC (1990) Effects of 1,25(OH)2D3 administration on bone in patients with renal failure. Kidney Int Suppl 29:S48\u2013S53","journal-title":"Kidney Int Suppl"},{"key":"481_CR54","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1007\/s00467-003-1326-7","volume":"19","author":"M Fernandez-Fuente","year":"2004","unstructured":"Fernandez-Fuente M, Santos F, Carbajo-Perez E, Rodriguez J, Weruga A, Amil B, Molinos F, Garcia E (2004) Growth plate height of uremic rats is influenced by severity and duration of renal failure. Pediatr Nephrol 19:187\u2013192","journal-title":"Pediatr Nephrol"},{"key":"481_CR55","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1681\/ASN.V105971","volume":"10","author":"A Cobo","year":"1999","unstructured":"Cobo A, Lopez JM, Carbajo E, Santos F, Alvarez J, Fernandez M, Weruaga A (1999) Growth plate cartilage formation and resorption are differentially depressed in growth retarded uremic rats. J Am Soc Nephrol 10:971\u2013979","journal-title":"J Am Soc Nephrol"},{"key":"481_CR56","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1046\/j.1523-1755.2000.00141.x","volume":"58","author":"SR Edmonson","year":"2000","unstructured":"Edmonson SR, Baker NL, Oh J, Kovacs G, Werther GA, Mehls O (2000) Growth hormone receptor abundance in tibial growth plates of uremic rats: GH\/IGF-I treatment. Kidney Int 58:62\u201370","journal-title":"Kidney Int"},{"key":"481_CR57","doi-asserted-by":"publisher","first-page":"1374","DOI":"10.1038\/ki.1995.193","volume":"47","author":"JD Hanna","year":"1995","unstructured":"Hanna JD, Santos F, Foreman JW, Chan JC, Han VK (1995) Insulin-like growth factor-I gene expression in the tibial epiphyseal growth plate of growth hormone-treated uremic rats. Kidney Int 47:1374\u20131382","journal-title":"Kidney Int"},{"key":"481_CR58","doi-asserted-by":"publisher","first-page":"1927","DOI":"10.1093\/ajcn\/31.10.1927","volume":"31","author":"O Mehls","year":"1978","unstructured":"Mehls O, Ritz E, Gilli G, Wangdak T, Krempien B (1978) Effect of vitamin D on growth in experimental uremia. Am J Clin Nutr 31:1927\u20131931","journal-title":"Am J Clin Nutr"},{"key":"481_CR59","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1007\/BF02556257","volume":"49","author":"G Klaus","year":"1991","unstructured":"Klaus G, Merke J, Eing H, Hugel U, Milde P, Reichel H, Ritz E, Mehls O (1991) 1,25(OH)2D3 receptor regulation and 1,25(OH)2D3 effects in primary cultures of growth cartilage cells of the rat. Calcif Tissue Int 49:340\u2013348","journal-title":"Calcif Tissue Int"},{"key":"481_CR60","doi-asserted-by":"publisher","first-page":"1307","DOI":"10.1210\/endo.135.4.7523093","volume":"135","author":"G Klaus","year":"1994","unstructured":"Klaus G, von Eichel B, May T, Hugel U, Mayer H, Ritz E, Mehls O (1994) Synergistic effects of parathyroid hormone and 1,25-dihydroxyvitamin D3 on proliferation and vitamin D receptor expression of rat growth cartilage cells. Endocrinology 135:1307\u20131315","journal-title":"Endocrinology"},{"key":"481_CR61","doi-asserted-by":"publisher","first-page":"1879","DOI":"10.1046\/j.1523-1755.1998.00199.x","volume":"54","author":"CP Sanchez","year":"1998","unstructured":"Sanchez CP, Salusky IB, Kuizon BD, Abdella P, Juppner H, Goodman WG (1998) Growth of long bones in renal failure: roles of hyperparathyroidism, growth hormone and calcitriol. Kidney Int 54:1879\u20131887","journal-title":"Kidney Int"},{"key":"481_CR62","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1097\/01.ASN.0000039565.56011.BE","volume":"14","author":"CP Sanchez","year":"2003","unstructured":"Sanchez CP, He YZ (2003) Effects of thyroparathyroidectomy, exogenous calcium, and short-term calcitriol therapy on the growth plate in renal failure. J Am Soc Nephrol 14:148\u2013158","journal-title":"J Am Soc Nephrol"},{"key":"481_CR63","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1007\/s004670000346","volume":"14","author":"O Mehls","year":"2000","unstructured":"Mehls O, Knoller N, Oh J, Wesch H, Wunsche B, Schmitt CP (2000) Daily but not pulse calcitriol therapy improves growth in experimental uremia. Pediatr Nephrol 14:658\u2013663","journal-title":"Pediatr Nephrol"},{"key":"481_CR64","doi-asserted-by":"publisher","first-page":"1160","DOI":"10.1038\/ki.1994.380","volume":"46","author":"WG Goodman","year":"1994","unstructured":"Goodman WG, Ramirez JA, Belin TR, Chon Y, Gales B, Segre GV, Salusky IB (1994) Development of adynamic bone in patients with secondary hyperparathyroidism after intermittent calcitriol therapy. Kidney Int 46:1160\u20131166","journal-title":"Kidney Int"},{"key":"481_CR65","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1007\/s00467-003-1091-7","volume":"18","author":"CP Schmitt","year":"2003","unstructured":"Schmitt CP, Ardissino G, Testa S, Claris-Appiani A, Mehls O (2003) Growth in children with chronic renal failure on intermittent versus daily calcitriol. Pediatr Nephrol 18:440\u2013444","journal-title":"Pediatr Nephrol"},{"key":"481_CR66","doi-asserted-by":"publisher","first-page":"1440","DOI":"10.1046\/j.1523-1755.2000.00306.x","volume":"58","author":"ML Picton","year":"2000","unstructured":"Picton ML, Moore PR, Mawer EB, Houghton D, Freemont AJ, Hutchison AJ, Gokal R, Hoyland JA (2000) Down-regulation of human osteoblast PTH\/PTHrP receptor mRNA in end-stage renal failure. Kidney Int 58:1440\u20131449, Oct","journal-title":"Kidney Int"},{"key":"481_CR67","doi-asserted-by":"publisher","first-page":"1904","DOI":"10.1093\/ndt\/gfh876","volume":"20","author":"Y Iwasaki-Ishizuka","year":"2005","unstructured":"Iwasaki-Ishizuka Y, Yamato H, Nii-Kono T, Kurokawa K, Fukagawa M (2005) Downregulation of parathyroid hormone receptor gene expression and osteoblastic dysfunction associated with skeletal resistance to parathyroid hormone in a rat model of renal failure with low turnover bone. Nephrol Dial Transplant 20:1904\u20131911","journal-title":"Nephrol Dial Transplant"},{"key":"481_CR68","doi-asserted-by":"publisher","first-page":"2008","DOI":"10.1093\/oxfordjournals.ndt.a027089","volume":"11","author":"P Urena","year":"1996","unstructured":"Urena P, Ferreira A, Morieux C, Drueke T, de Vernejoul MC (1996) PTH\/PTHrP receptor mRNA is down-regulated in epiphyseal cartilage growth plate of uraemic rats. Nephrol Dial Transplant 11:2008\u20132016","journal-title":"Nephrol Dial Transplant"},{"key":"481_CR69","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1046\/j.1523-1755.1998.00724.x","volume":"53","author":"BD Kuizon","year":"1998","unstructured":"Kuizon BD, Goodman WG, Juppner H, Boechat I, Nelson P, Gales B, Salusky IB (1998) Diminished linear growth during intermittent calcitriol therapy in children undergoing CCPD. Kidney Int 53:205\u2013211","journal-title":"Kidney Int"},{"key":"481_CR70","doi-asserted-by":"publisher","first-page":"800","DOI":"10.1016\/0140-6736(91)91429-X","volume":"337","author":"G Klaus","year":"1991","unstructured":"Klaus G, Mehls O, Hinderer J, Ritz E (1991) Is intermittent oral calcitriol safe and effective in renal secondary hyperparathyroidism? Lancet 337:800\u2013801","journal-title":"Lancet"},{"key":"481_CR71","unstructured":"K\/DOQI (2004) Clinical practice guidelines for bone metabolism and disease in chronic kidney disease. Available at: https:\/\/doi.org\/www.kidney.org\/professionals\/kdoqi\/guidelines_bone\/index.htm"},{"key":"481_CR72","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1007\/s00467-005-2082-7","volume":"21","author":"G Klaus","year":"2006","unstructured":"Klaus G, Watson A, Edefonti A, Fischbach M, Ronnholm K, Schaefer F, Simkova E, Stefanidis CJ, Strazdins V, Vande Walle J, Schroder C, Zurowska A, Ekim M; European Pediatric Dialysis Working Group (EPDWG) (2006) Prevention and treatment of renal osteodystrophy in children with chronic renal failure: European guidelines. Pediatr Nephrol 21:151\u2013159","journal-title":"Pediatr Nephrol"},{"key":"481_CR73","doi-asserted-by":"publisher","first-page":"1236","DOI":"10.1007\/s00467-003-1284-0","volume":"18","author":"S Waller","year":"2003","unstructured":"Waller S, Ledermann S, Trompeter R, van\u2019t Hoff W, Ridout D, Rees L (2003) Catch-up growth with normal parathyroid hormone levels in chronic renal failure. Pediatr Nephrol 18:1236\u20131241","journal-title":"Pediatr Nephrol"},{"key":"481_CR74","doi-asserted-by":"publisher","first-page":"1390","DOI":"10.1007\/s00467-004-1670-2","volume":"19","author":"AM Bakr","year":"2004","unstructured":"Bakr AM (2004) Bone mineral density and bone turnover markers in children with chronic renal failure. Pediatr Nephrol 19:1390\u20131393","journal-title":"Pediatr Nephrol"},{"key":"481_CR75","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1055\/s-2001-14931","volume":"33","author":"D Bonofiglio","year":"2001","unstructured":"Bonofiglio D, Maggiolini M, Catalano S, Marsico S, Aquila S, Ando S (2001) Bone mineral density is inversely related to parathyroid hormone in adolescent girls. Horm Metab Res 33:170\u2013174","journal-title":"Horm Metab Res"},{"key":"481_CR76","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1053\/j.ajkd.2003.12.003","volume":"43","author":"KJ Martin","year":"2004","unstructured":"Martin KJ, Olgaard K, Coburn JW, Coen GM, Fukagawa M, Langman C, Malluche HH, McCarthy JT, Massry SG, Mehls O, Salusky IB, Silver JM, Smogorzewski MT, Slatopolsky EM, McCann L; Bone Turnover Work Group (2004) Diagnosis, assessment, and treatment of bone turnover abnormalities in renal osteodystrophy. Am J Kidney Dis 43:558\u2013565","journal-title":"Am J Kidney Dis"},{"key":"481_CR77","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1016\/S0272-6386(03)00197-5","volume":"41","author":"AR Bervoets","year":"2003","unstructured":"Bervoets AR, Spasovski GB, Behets GJ, Dams G, Polenakovic MH, Zafirovska K, Van Hoof VO, De Broe ME, D\u2019Haese PC (2003) Useful biochemical markers for diagnosing renal osteodystrophy in predialysis end-stage renal failure patients. Am J Kidney Dis 41:997\u20131007","journal-title":"Am J Kidney Dis"},{"key":"481_CR78","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1515\/JPEM.1999.12.6.879","volume":"12","author":"J Piscitelli","year":"1999","unstructured":"Piscitelli J, Cabansag MR, Silverstein DM (1999) Correlation among markers of renal osteodystrophy in pediatric hemodialysis patients. J Pediatr Endocrinol Metab 12:879\u2013886","journal-title":"J Pediatr Endocrinol Metab"},{"key":"481_CR79","first-page":"140","volume":"48","author":"AK Bayazit","year":"2006","unstructured":"Bayazit AK, Cengiz N, Anarat R, Noyan A, Anarat A (2006) Peritoneal clearance of biochemical markers of bone turnover in children with end stage renal failure on peritoneal dialysis. Turk J Pediatr 48:140\u2013142","journal-title":"Turk J Pediatr"},{"key":"481_CR80","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1177\/089686080602600112","volume":"26","author":"M Avila-Diaz","year":"2006","unstructured":"Avila-Diaz M, Matos M, Garcia-Lopez E, Prado MD, Castro-Vazquez F, Ventura MD, Gonzalez E, Amato D, Paniagua R (2006) Serum markers of low-turnover bone disease in Mexican children with chronic kidney disease undergoing dialysis. Perit Dial Int 26:78\u201384","journal-title":"Perit Dial Int"},{"key":"481_CR81","doi-asserted-by":"publisher","first-page":"662","DOI":"10.1093\/ndt\/13.3.662","volume":"13","author":"B Behnke","year":"1998","unstructured":"Behnke B, Kemper M, Kruse HP, Muller-Wiefel DE (1998) Bone alkaline phosphatase in children with chronic renal failure. Nephrol Dial Transplant 13:662\u2013667","journal-title":"Nephrol Dial Transplant"},{"key":"481_CR82","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1007\/s004670050463","volume":"12","author":"CJ Stefanidis","year":"1998","unstructured":"Stefanidis CJ (1998) Chronic renal insufficiency and recombinant human growth hormone treatment. Pediatr Nephrol 12:340","journal-title":"Pediatr Nephrol"},{"key":"481_CR83","first-page":"321","volume":"10","author":"F Schaefer","year":"1994","unstructured":"Schaefer F, Wuhl E, Haffner D, Mehls O (1994) Stimulation of growth by recombinant human growth hormone in children undergoing peritoneal or hemodialysis treatment. German Study Group for growth hormone treatment in chronic renal failure. Adv Perit Dial 10:321\u2013326","journal-title":"Adv Perit Dial"},{"key":"481_CR84","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1007\/s004670050459","volume":"12","author":"E Berard","year":"1998","unstructured":"Berard E, Crosnier H, Six-Beneton A, Chevallier T, Cochat P, Broyer M (1998) Recombinant human growth hormone treatment of children on hemodialysis. French Society of Pediatric Nephrology. Pediatr Nephrol 12:304\u2013310","journal-title":"Pediatr Nephrol"},{"key":"481_CR85","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1007\/s00467-004-1801-9","volume":"20","author":"JA Kari","year":"2005","unstructured":"Kari JA, Rees L (2005) Growth hormone for children with chronic renal failure and on dialysis. Pediatr Nephrol 20:618\u2013621","journal-title":"Pediatr Nephrol"},{"key":"481_CR86","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1007\/s00467-006-0020-y","volume":"21","author":"JD Mahan","year":"2006","unstructured":"Mahan JD, Warady BA; Consensus Committee (2006) Assessment and treatment of short stature in pediatric patients with chronic kidney disease: a consensus statement. Pediatr Nephrol 21:917\u2013930","journal-title":"Pediatr Nephrol"}],"container-title":["Pediatric Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-007-0481-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00467-007-0481-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.springerlink.com\/index\/pdf\/10.1007\/s00467-007-0481-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-007-0481-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,18]],"date-time":"2022-04-18T22:07:50Z","timestamp":1650319670000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00467-007-0481-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,9]]},"references-count":86,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2007,9]]}},"alternative-id":["481"],"URL":"https:\/\/doi.org\/10.1007\/s00467-007-0481-7","relation":{},"ISSN":["0931-041X","1432-198X"],"issn-type":[{"value":"0931-041X","type":"print"},{"value":"1432-198X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,9]]},"assertion":[{"value":"5 November 2006","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 February 2007","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 March 2007","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 September 2007","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}