{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T21:14:23Z","timestamp":1760908463828},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Nephrol"],"published-print":{"date-parts":[[2009,1]]},"DOI":"10.1007\/s00467-008-0969-9","type":"journal-article","created":{"date-parts":[[2008,9,17]],"date-time":"2008-09-17T13:51:54Z","timestamp":1221659514000},"page":"105-111","source":"Crossref","is-referenced-by-count":12,"title":["Urine macrophage migration inhibitory factor (MIF) in children with urinary tract infection: a possible predictor of acute pyelonephritis"],"prefix":"10.1007","volume":"24","author":[{"given":"Hasan","family":"Otukesh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyed-Mohammad","family":"Fereshtehnejad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rozita","family":"Hoseini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sepideh","family":"Hekmat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamid","family":"Chalian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Majid","family":"Chalian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arash","family":"Bedayat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reza","family":"Salman Yazdi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saeed","family":"Sabaghi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saeed","family":"Mahdavi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,1,1]]},"reference":[{"key":"969_CR1","first-page":"986","volume":"41","author":"JC Criag","year":"2000","unstructured":"Criag JC, Wheeler DM, Irwig L (2000) How accurate is dimercatosuccinic acid scintigraphy for the diagnosis of acute pyelonephritis? A meta-analysis of experimental studies. J Nuclear Med 41:986\u2013993","journal-title":"J Nuclear Med"},{"key":"969_CR2","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1007\/BF00860724","volume":"9","author":"J Martinelli","year":"1995","unstructured":"Martinelli J, Claesson I, Lidin-Janson G, Jodal U (1995) Urinary infection, reflux and renal scarring in females continuously followed for 13\u201338\u00a0years. Pediatr Nephrol 9:131\u2013136","journal-title":"Pediatr Nephrol"},{"key":"969_CR3","first-page":"565","volume":"8","author":"J Smellie","year":"1975","unstructured":"Smellie J, Edwards D, Hunter N, Normand ICS, Prescod N (1975) Vesicoureteral reflux and renal scarring. Kidney Int 8:565\u2013575","journal-title":"Kidney Int"},{"key":"969_CR4","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1007\/s004670050243","volume":"11","author":"HG Rushton","year":"1997","unstructured":"Rushton HG (1997) The evaluation of acute pyelonephritis and renal scarring with technetium 99m-dimercaptosuccinic acid renal scintigraphy: evolving concepts and future directions. Pediatr Nephrol 11:108\u2013120","journal-title":"Pediatr Nephrol"},{"key":"969_CR5","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1542\/peds.104.1.79","volume":"104","author":"A Hoberman","year":"1999","unstructured":"Hoberman A, Wald ER, Hickey RW, Baskin M, Charron M, Majd M, Kearney DH, Reynolds EA, Ruley J, Janosky JE (1999) Oral versus initial intravenous therapy for urinary tract infections in young febrile children. Pediatrics 104:79\u201386","journal-title":"Pediatrics"},{"key":"969_CR6","doi-asserted-by":"publisher","first-page":"1338","DOI":"10.1136\/adc.67.11.1338","volume":"67","author":"B Jakobsson","year":"1992","unstructured":"Jakobsson B, Soderlundh S, Berg U (1992) Diagnostic significance of 99mTc-dimercaptosuccinic acid (DMSA) scintigraphy in urinary tract infection. Arch Dis Child 67:1338\u20131342","journal-title":"Arch Dis Child"},{"key":"969_CR7","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/S0022-3476(94)70248-9","volume":"124","author":"D Benador","year":"1994","unstructured":"Benador D, Benador N, Slosman DO, Nussle D, Mermillod B, Girardin E (1994) Cortical scintigraphy in the evaluation of renal parenchymal changes in children with pyelonephritis. J Pediatr 124:17\u201320","journal-title":"J Pediatr"},{"key":"969_CR8","doi-asserted-by":"publisher","first-page":"1439","DOI":"10.1007\/s00467-005-1925-6","volume":"20","author":"N Ataei","year":"2005","unstructured":"Ataei N, Madani A, Habibi R, Khorasani M (2005) Evaluation of acute pyelonephritis with DMSA scans in children presenting after the age of 5\u00a0years. Pediatr Nephrol 20:1439\u20131444","journal-title":"Pediatr Nephrol"},{"key":"969_CR9","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1002\/art.10728","volume":"48","author":"EF Morand","year":"2003","unstructured":"Morand EF, Bucala R, Leech M (2003) Macrophage migration inhibitory factor: an emerging therapeutic target in rheumatoid arthritis. Arthritis Rheum 48:291\u2013299","journal-title":"Arthritis Rheum"},{"key":"969_CR10","doi-asserted-by":"publisher","first-page":"7849","DOI":"10.1073\/pnas.93.15.7849","volume":"93","author":"M Bacher","year":"1996","unstructured":"Bacher M, Metz CN, Calandra T, Mayer K, Chesney J, Lohoff M, Gemsa D, Donnelly T, Bucala R (1996) An essential regulatory role for macrophage migration inhibitory factor in T-cell activation. Proc Natl Acad Sci USA 93:7849\u20137854","journal-title":"Proc Natl Acad Sci USA"},{"key":"969_CR11","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/S0065-2776(08)60598-2","volume":"66","author":"CN Metz","year":"1997","unstructured":"Metz CN, Bucala R (1997) Role of macrophage migration inhibitory factor in the regulation of the immune response. Adv Immunol 66:197\u2013223","journal-title":"Adv Immunol"},{"key":"969_CR12","first-page":"703","volume-title":"Cytokine reference: a compendium of cytokines and other mediators of host defense, vol 1","author":"CN Metz","year":"2001","unstructured":"Metz CN, Bucala R (2001) MIF. In: Oppenheim JJ, Feldman M (eds) Cytokine reference: a compendium of cytokines and other mediators of host defense, vol 1. Academic Press, San Diego, pp 703\u2013716"},{"key":"969_CR13","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1053\/gast.2001.27205","volume":"121","author":"XR Huang","year":"2001","unstructured":"Huang XR, Hui CWC, Chen Y-X, Chun B, Wong Y, Fung PCW, Metz C, Cho CH, Hui WM, Bucala R, Lam S-K, Lan HY (2001) Macrophage migration inhibitory factor is an important mediator in the pathogenesis of gastric inflammation in rats. Gastroenterology 121:619\u2013630","journal-title":"Gastroenterology"},{"key":"969_CR14","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1053\/gast.2002.34236","volume":"123","author":"T Ohkawara","year":"2002","unstructured":"Ohkawara T, Nishihira J, Takeda J, Hige S, Kato M, Sugiyama T, Iwanaga T, Nakamura H, Mizue Y, Asaka M (2002) Amelioration of dextran sulfate sodium-induced colitis by anti-macrophage migration inhibitory factor antibody in mice. Gastroenterology 123:256\u2013270","journal-title":"Gastroenterology"},{"key":"969_CR15","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1007\/BF03401919","volume":"4","author":"M Bacher","year":"1998","unstructured":"Bacher M, Meinhardt A, Lan HY, Dhabhar FS, Mu W, Metz CN, Chesney JA, Gemsa D, Donnelly T, Atkins RC, Bucala R (1998) MIF expression in the rat brain: implications for neuronal function. Mol Med 4:217\u2013230","journal-title":"Mol Med"},{"key":"969_CR16","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1097\/01.ju.0000161606.15696.79","volume":"174","author":"PL Vera","year":"2005","unstructured":"Vera PL, Iczkowski KA, Leng L, Bucala R, Meyer-Siegler KL (2005) Macrophage migration inhibitory factor is released as a complex with alpha1-inhibitor-3 in the intraluminal fluid during bladder inflammation in the rat. J Urol 174:338\u2013343","journal-title":"J Urol"},{"key":"969_CR17","doi-asserted-by":"publisher","first-page":"1523","DOI":"10.1016\/S0022-5347(05)00650-6","volume":"175","author":"KL Meyer-Siegler","year":"2006","unstructured":"Meyer-Siegler KL, Iczkowski KA, Vera PL (2006) Macrophage migration inhibitory factor is increased in the urine of patients with urinary tract infection: macrophage migration inhibitory factor-protein complexes in human urine. J Urol 175:1523\u20131528","journal-title":"J Urol"},{"key":"969_CR18","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/1471-2202-4-17","volume":"4","author":"PL Vera","year":"2003","unstructured":"Vera PL, Meyer-Siegler KL (2003) Anatomical location of macrophage migration inhibitory factor in urogenital tissues, peripheral ganglia and lumbosacral spinal cord of the rat. BMC Neurosci 4:17","journal-title":"BMC Neurosci"},{"key":"969_CR19","first-page":"1007","volume-title":"Pediatric nephrology","author":"S Hansson","year":"2004","unstructured":"Hansson S, Jodal U (2004) Urinary tract infection. In: Avner E, Harmon W, Niaudet P (eds) Pediatric nephrology, 5th edn. Williams & Wilkins, Philadelphia, pp 1007\u20131026","edition":"5"},{"key":"969_CR20","unstructured":"Knapp RG, Miller MC (eds) (1992) Describing the performance of a diagnostic test. In: Knapp RG, Miller MC (eds) Clinical epidemiology and biostatistics, 1st edn. Williams & Wilkins, Baltimore, pp 41\u201342"},{"key":"969_CR21","doi-asserted-by":"publisher","first-page":"1895","DOI":"10.1084\/jem.179.6.1895","volume":"179","author":"T Calandra","year":"1994","unstructured":"Calandra T, Bernhagen J, Mitchell RA, Bucala R (1994) The macrophage is an important and previously unrecognized source of macrophage migration inhibitory factor. J Exp Med 179:1895\u20131902","journal-title":"J Exp Med"},{"key":"969_CR22","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1007\/BF03401892","volume":"1","author":"T Nishino","year":"1995","unstructured":"Nishino T, Bernhagen J, Shiiki H, Calandra T, Dohi K, Bucala R (1995) Localisation of macrophage migration inhibitory factor (MIF) to secretory granules within the corticotrophic and thyrotrophic cells of the pituitary gland. Mol Med 1:781\u2013788","journal-title":"Mol Med"},{"key":"969_CR23","first-page":"235","volume":"150","author":"M Bacher","year":"1997","unstructured":"Bacher M, Meinhardt A, Lan HY, Mu W, Metz CN, Chesney JA, Calandra T, Gemsa D, Donnelly T, Atkins RC, Bucala R (1997) Migration inhibitory factor expression in experimentally induced endotoxemia. Am J Pathol 150:235\u2013246","journal-title":"Am J Pathol"},{"key":"969_CR24","doi-asserted-by":"publisher","first-page":"5090","DOI":"10.1210\/endo.137.11.8895383","volume":"137","author":"A Meinhardt","year":"1996","unstructured":"Meinhardt A, Bacher M, McFarlane JR, Metz CN, Seitz J, Hedger MP, de Kretser DM, Bucala R (1996) Macrophage migration inhibitory factor production by Leydig cells: Evidence for a role in the regulation of testicular function. Endocrinology 137:5090\u20135095","journal-title":"Endocrinology"},{"key":"969_CR25","doi-asserted-by":"publisher","first-page":"4782","DOI":"10.1073\/pnas.94.9.4782","volume":"94","author":"G Waeber","year":"1997","unstructured":"Waeber G, Calandra T, Roduit R, Haefliger JA, Bonny C, Thompson N, Thorens B, Temler E, Meinhardt A, Bacher M, Metz CN, Nicod P, Bucala R (1997) Insulin secretion is regulated by the glucose-dependent production of islet beta cell macrophage migration inhibitory factor. Proc Natl Acad Sci USA 94:4782\u20134787","journal-title":"Proc Natl Acad Sci USA"},{"key":"969_CR26","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1007\/BF03401919","volume":"4","author":"M Bacher","year":"1998","unstructured":"Bacher M, Meinhardt A, Lan HY, Dhabhar FS, Mu W, Metz CN, Chesney JA, Gemsa D, Donnelly T, Atkins RC, Bucala R (1998) MIF expression in the rat brain: Implications for neuronal function. Mol Med 4:217\u2013230","journal-title":"Mol Med"},{"key":"969_CR27","doi-asserted-by":"publisher","first-page":"2869","DOI":"10.1172\/JCI1524","volume":"101","author":"AG Rossi","year":"1998","unstructured":"Rossi AG, Haslett C, Hirani N, Greening AP, Rahman I, Metz CN, Bucala R, Donnelly SC (1998) Human circulating eosinophils secrete macrophage migration inhibitory factor (MIF). Potential role in asthma. J Clin Invest 101:2869\u20132874","journal-title":"J Clin Invest"},{"key":"969_CR28","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1046\/j.1365-2133.1999.03206.x","volume":"141","author":"M Steinhoff","year":"1999","unstructured":"Steinhoff M, Meinhardt A, Steinhoff A, Gemsa D, Bucala R, Bacher M (1999) Evidence for a role of macrophage migration inhibitory factor in psoriatic skin disease. Br J Dermatol 141:1061\u20131066","journal-title":"Br J Dermatol"},{"key":"969_CR29","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1007\/BF03401805","volume":"3","author":"HY Lan","year":"1997","unstructured":"Lan HY, Yang N, Metz C, Mu W, Song Q, Nikolic-Paterson DJ, Bacher M, Bucala R, Atkins RC (1997) TNF-alpha up-regulates renal MIF expression in rat crescentic glomerulonephritis. Mol Med 3:136\u2013144","journal-title":"Mol Med"},{"key":"969_CR30","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1046\/j.1365-2249.1997.3671260.x","volume":"108","author":"K Miyazaki","year":"1997","unstructured":"Miyazaki K, Isbel NM, Lan HY, Hattori M, Ito K, Bacher M, Bucala R, Atkins RC, Nikolic-Paterson DJ (1997) Up-regulation of macrophage colony-stimulating factor (M-CSF) and migration inhibitory factor (MIF) expression and monocyte recruitment during lipid-induced glomerular injury in the exogenous hypercholesterolaemic (ExHC) rat. Clin Exp Immunol 108:318\u2013323","journal-title":"Clin Exp Immunol"},{"key":"969_CR31","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1111\/j.1440-1797.1996.tb00123.x","volume":"2","author":"Q Song","year":"1998","unstructured":"Song Q, Nikolic-Paterson DJ, Atkins RC, Bacher M, Bucala R, Lan HY (1998) Delayed-type hypersensitivity mediates Bowman\u2019s capsule rupture in Tamm-Horsfall protein-induced tubulointerstitial nephritis in the rat. Nephrology 2:417\u2013427","journal-title":"Nephrology"},{"key":"969_CR32","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1681\/ASN.V93417","volume":"9","author":"GH Tesch","year":"1998","unstructured":"Tesch GH, Nikolic-Paterson DJ, Metz CN, Mu W, Bacher M, Bucala R, Atkins RC, Lan HY (1998) Rat mesangial cells express macrophage migration inhibitory factor in vitro and in vivo. J Am Soc Nephrol 9:417\u2013424","journal-title":"J Am Soc Nephrol"},{"key":"969_CR33","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1089\/107999004772719918","volume":"24","author":"KL Meyer-Siegler","year":"2004","unstructured":"Meyer-Siegler KL, Ordorica RC, Vera PL (2004) Macrophage migration inhibitory factor is upregulated in an endotoxin-induced model of bladder inflammation in rats. J Interferon Cytokine Res 24:55\u201363","journal-title":"J Interferon Cytokine Res"},{"key":"969_CR34","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1097\/01.ju.0000066001.10343.d5","volume":"170","author":"PL Vera","year":"2003","unstructured":"Vera PL, Ordorica RC, Meyer-Siegler KL (2003) Hydrochloric acid-induced changes in macrophage migration inhibitory factor in the bladder, peripheral and central nervous system of the rat. J Urol 170:623\u2013627","journal-title":"J Urol"},{"key":"969_CR35","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1046\/j.1365-2249.2003.02076.x","volume":"131","author":"O Hertting","year":"2003","unstructured":"Hertting O, Khalil A, Jaremko G, Chromek M, Li YH, Bakhiet M, Bartfai T, Tullus K, Brauner A (2003) Enhanced chemokine response in experimental acute Escherichia coli pyelonephritis in IL-1\u03b2-deficient mice. Clin Exp Immunol 131:225\u2013233","journal-title":"Clin Exp Immunol"}],"container-title":["Pediatric Nephrology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-008-0969-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00467-008-0969-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-008-0969-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-008-0969-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,16]],"date-time":"2021-09-16T17:06:52Z","timestamp":1631812012000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00467-008-0969-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["969"],"URL":"https:\/\/doi.org\/10.1007\/s00467-008-0969-9","relation":{},"ISSN":["0931-041X","1432-198X"],"issn-type":[{"value":"0931-041X","type":"print"},{"value":"1432-198X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,1]]}}}