{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T13:05:10Z","timestamp":1758891910182},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Nephrol"],"published-print":{"date-parts":[[2009,5]]},"DOI":"10.1007\/s00467-008-1026-4","type":"journal-article","created":{"date-parts":[[2008,10,13]],"date-time":"2008-10-13T15:45:27Z","timestamp":1223912727000},"page":"1065-1070","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Complete remission of nephrotic syndrome in an infant with focal segmental glomerulosclerosis: is it renin\u2013angiotensin blockade?"],"prefix":"10.1007","volume":"24","author":[{"given":"Neveen A.","family":"Soliman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magdi","family":"Francis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saskia F.","family":"Heeringa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gil","family":"Chernin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,5,1]]},"reference":[{"key":"1026_CR1","first-page":"380","volume":"1","author":"Arbeitsgemeinschaft f\u00fcr P\u00e4diatrische Nephrologie","year":"1988","unstructured":"Arbeitsgemeinschaft f\u00fcr P\u00e4diatrische Nephrologie (1988) Short versus standard prednisone therapy for initial treatment of idiopathic nephrotic syndrome in children. Lancet 1:380\u2013383","journal-title":"Lancet"},{"key":"1026_CR2","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1007\/s004670050414","volume":"12","author":"N Baqi","year":"1998","unstructured":"Baqi N, Singh A, Balachandra A, Ahmed H, Nicastri A, Kytinski S, Homel P, Tejani A (1998) The paucity of minimal change disease in adolescents with primary nephrotic syndrome. Pediatr Nephrol 12:105\u2013107","journal-title":"Pediatr Nephrol"},{"key":"1026_CR3","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1007\/BF00866790","volume":"10","author":"I Ichikawa","year":"1996","unstructured":"Ichikawa I, Fogo A (1996) Focal segmental glomerulosclerosis. Pediatr Nephrol 10:374\u2013391","journal-title":"Pediatr Nephrol"},{"key":"1026_CR4","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1007\/s004670050555","volume":"13","author":"T Srivastava","year":"1999","unstructured":"Srivastava T, Simon S, Alon U (1999) High incidence of focal segmental glomerulosclerosis in nephrotic syndrome in childhood. Pediatr Nephrol 13:13\u201318","journal-title":"Pediatr Nephrol"},{"key":"1026_CR5","first-page":"213","volume":"10","author":"JS Cameron","year":"1978","unstructured":"Cameron JS, Turner DR, Ogg CS, Chantler C, Williams DG (1978) The long-term prognosis of patients with focal segmental glomerulosclerosis. Clin Nephrol 10:213\u2013218","journal-title":"Clin Nephrol"},{"key":"1026_CR6","doi-asserted-by":"publisher","first-page":"773","DOI":"10.1016\/S0272-6386(12)80128-4","volume":"23","author":"SM Korbet","year":"1994","unstructured":"Korbet SM, Schwartz MM, Lewis EG (1994) Primary focal segmental glomerulosclerosis. Clinical course and response to therapy. Am J Kidney Dis 23:773\u2013783","journal-title":"Am J Kidney Dis"},{"key":"1026_CR7","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1016\/0272-6386(95)90120-5","volume":"25","author":"JJ Rydell","year":"1995","unstructured":"Rydell JJ, Korbet SM, Borok RZ, Schwartz MM (1995) Focal glomerular sclerosis in adults. Presentation, course and response to treatment. Am J Kidney Dis 25:534\u2013542","journal-title":"Am J Kidney Dis"},{"key":"1026_CR8","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1007\/BF00862503","volume":"4","author":"SA Mendoza","year":"1990","unstructured":"Mendoza SA, Reznik VM, Grisworld WR, Krensky AM, Yorgin PD, Tune BM (1990) Treatment of steroid-resistant focal segmental glomerulosclerosis with pulse methylprednisolone and alkylating agents. Pediatr Nephrol 4:303\u2013307","journal-title":"Pediatr Nephrol"},{"key":"1026_CR9","doi-asserted-by":"publisher","first-page":"772","DOI":"10.1007\/s004670050216","volume":"10","author":"BM Tune","year":"1996","unstructured":"Tune BM, Lieberman E, Mendoza SA (1996) Steroid-resistant nephrotic focal segmental glomerulosclerosis: a treatable disease. Pediatr Nephrol 10:772\u2013778","journal-title":"Pediatr Nephrol"},{"key":"1026_CR10","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1007\/s004670000494","volume":"16","author":"PD Yorgin","year":"2001","unstructured":"Yorgin PD, Krasher J, Al-Uzri AY (2001) Pulse methylprednisolone treatment of idiopathic steroid-resistant nephrotic syndrome. Pediatr Nephrol 16:245\u2013250","journal-title":"Pediatr Nephrol"},{"key":"1026_CR11","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1016\/0002-9343(87)90155-0","volume":"82","author":"Y Pei","year":"1987","unstructured":"Pei Y, Cattran D, Delmore T, Katz A, Lang A, Rance P (1987) Evidence suggesting under-treatment in adults with idiopathic focal segmental glomerulosclerosis. Regional Glomerulonephritis Registry Study. Am J Med 82:938\u2013944","journal-title":"Am J Med"},{"key":"1026_CR12","first-page":"53","volume":"36","author":"G Banfi","year":"1991","unstructured":"Banfi G, Moriggi M, Sabadini E, Fellin G, D\u2019Amico G, Ponticelli C (1991) The impact of prolonged immunosuppression on the outcome of idiopathic focal-segmental glomerulosclerosis with nephrotic syndrome in adults. A collaborative retrospective study. Clin Nephrol 36:53\u201359","journal-title":"Clin Nephrol"},{"key":"1026_CR13","doi-asserted-by":"publisher","first-page":"c83","DOI":"10.1159\/000093994","volume":"104","author":"CM Stirling","year":"2006","unstructured":"Stirling CM (2006) Focal segmental glomerulosclerosis\u2014does treatment work? Nephron Clin Pract 104:c83\u2013c84","journal-title":"Nephron Clin Pract"},{"key":"1026_CR14","first-page":"115","volume":"33","author":"M Wehrmann","year":"1990","unstructured":"Wehrmann M, Bohle A, Held H, Schumm G, Kendziorra H, Pressler H (1990) Long-term prognosis of focal sclerosing glomerulonephritis. An analysis of 250 cases with particular regard to tubulointerstitial changes. Clin Nephrol 33:115\u2013122","journal-title":"Clin Nephrol"},{"key":"1026_CR15","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1053\/ajkd.1998.v32.pm9669427","volume":"32","author":"DC Cattran","year":"1998","unstructured":"Cattran DC, Rao P (1998) Long-term outcome in children and adults with classic focal segmental glomerulosclerosis. Am J Kidney Dis 32:72\u201379","journal-title":"Am J Kidney Dis"},{"key":"1026_CR16","first-page":"119","volume":"S57","author":"JS Cameron","year":"1996","unstructured":"Cameron JS (1996) The enigma of focal segmental glomerulosclerosis. Kidney Int Suppl S57:119\u2013131","journal-title":"Kidney Int Suppl"},{"key":"1026_CR17","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1093\/ndt\/14.3.550","volume":"14","author":"A Schmidt","year":"1999","unstructured":"Schmidt A, Mayer G (1999) The diagnostic trash bin of focal and segmental glomerulosclerosis\u2014an effort to provide rational clinical guidelines. Nephrol Dial Transplant 14:550\u2013552","journal-title":"Nephrol Dial Transplant"},{"key":"1026_CR18","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1097\/00005792-198609000-00003","volume":"65","author":"S Korbet","year":"1986","unstructured":"Korbet S, Schwartz M, Lewis EJ (1986) The prognosis of focal segmental glomerulosclerosis of adulthood. Medicine 65:304\u2013311","journal-title":"Medicine"},{"key":"1026_CR19","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1111\/j.1523-1755.2004.00775.x","volume":"66","author":"RG Ruf","year":"2004","unstructured":"Ruf RG, Schultheiss M, Lichtenberger A, Karle SM, Zalewski I, Mucha B, Everding AS, Neuhaus T, Patzer L, Plank C, Haas JP, Ozaltin F, Imm A, Fuchshuber A, Bakkaloglu A, Hildebrandt F, Members of the APN study group (2004) Prevalence of WT1 mutations in a large cohort of patients with steroid-resistant and steroid-sensitive nephrotic syndrome. Kidney Int 66:564\u2013570","journal-title":"Kidney Int"},{"key":"1026_CR20","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.semnephrol.2005.09.001","volume":"26","author":"N Daskalakis","year":"2005","unstructured":"Daskalakis N, Winn MP (2005) Focal and segmental glomerulosclerosis: varying biologic mechanisms underlie a final histologic end point. Semin Nephrol 26:89\u201394","journal-title":"Semin Nephrol"},{"key":"1026_CR21","doi-asserted-by":"publisher","first-page":"1397","DOI":"10.1038\/ng1918","volume":"38","author":"B Hinkes","year":"2006","unstructured":"Hinkes B, Wiggins RC, Gbadegesin R, Vlangos CN, Seelow D, N\u00fcrnberg G, Garg P, Verma R, Chaib H, Hoskins BE, Ashraf S, Becker C, Hennies HC, Goyal M, Wharram BL, Schachter AD, Mudumana S, Drummond I, Kerjaschki D, Waldherr R, Dietrich A, Ozaltin F, Bakkaloglu A, Cleper R, Basel-Vanagaite L, Pohl M, Griebel M, Tsygin AN, Soylu A, M\u00fcller D, Sorli CS, Bunney TD, Katan M, Liu J, Attanasio M, O\u2019Toole JF, Hasselbacher K, Mucha B, Otto EA, Airik R, Kispert A, Kelley GG, Smrcka AV, Gudermann T, Holzman LB, N\u00fcrnberg P, Hildebrandt F (2006) Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible. Nat Genet 38:1397\u20131405","journal-title":"Nat Genet"},{"key":"1026_CR22","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1203\/01.pdr.0000202150.71520.9e","volume":"59","author":"T Benzing","year":"2006","unstructured":"Benzing T (2006) Genetic testing comes of age: WT1 mutations in steroid-resistant nephrotic syndrome. Pediatr Res 59:165\u2013166","journal-title":"Pediatr Res"},{"key":"1026_CR23","doi-asserted-by":"publisher","first-page":"722","DOI":"10.1097\/01.ASN.0000113552.59155.72","volume":"15","author":"RG Ruf","year":"2004","unstructured":"Ruf RG, Lichtenberger A, Karle SM, Haas JP, Anacleto FE, Schultheiss M, Zalewski I, Imm A, Ruf EM, Mucha B, Bagga A, Neuhaus T, Fuchshuber A, Bakkalouglu A, Hildebrandt F, The Arbeitsgemeinschaft f\u00fcr P\u00e4diatrische Nephrology (2004) Patients with mutations in NPHS2 (podocin) do not respond to standard steroid treatment of nephrotic syndrome. J Am Soc Nephrol 15:722\u2013732","journal-title":"J Am Soc Nephrol"},{"key":"1026_CR24","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1203\/01.pdr.0000196717.94518.f0","volume":"59","author":"B Mucha","year":"2006","unstructured":"Mucha B, Ozaltin F, Hinkes BG, Hasselbacher K, Ruf RG, Schultheiss M, Hangan D, Hoskins BE, Everding AS, Bogdanovic R, Seeman T, Hoppe B, Hildebrandt F, Members of the APN Study Group (2006) Mutations in the Wilms\u2019 tumor 1 gene cause isolated steroid resistant nephrotic syndrome and occur in exons 8 and 9. Pediatr Res 59:325\u2013331","journal-title":"Pediatr Res"},{"key":"1026_CR25","doi-asserted-by":"publisher","first-page":"e907","DOI":"10.1542\/peds.2006-2164","volume":"119","author":"BG Hinkes","year":"2007","unstructured":"Hinkes BG, Mucha B, Vlangos CN, Gbadegesin R, Liu J, Hasselbacher K, Hangan D, Ozaltin F, Zenker M, Hildebrandt F, Members of the Arbeitsgemeinschaft f\u00fcr P\u00e4diatrische Nephrologie Study Group (2007) Nephrotic syndrome in the first year of life: two thirds of cases are caused by mutations in 4 genes (NPHS1, NPHS2, WT1, and LAMB2). Pediatrics 119:e907\u2013e919","journal-title":"Pediatrics"},{"key":"1026_CR26","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1097\/00008480-200304000-00006","volume":"15","author":"C Benchimol","year":"2003","unstructured":"Benchimol C (2003) Focal segmental glomerulosclerosis: pathogenesis and treatment. Curr Opin Pediatr 15:171\u2013180","journal-title":"Curr Opin Pediatr"},{"key":"1026_CR27","first-page":"380","volume":"1","author":"Arbeitsgemeinschaft f\u00fcr P\u00e4diatrische Nephrologie","year":"1988","unstructured":"Arbeitsgemeinschaft f\u00fcr P\u00e4diatrische Nephrologie (1988) Short versus standard prednisone therapy for initial treatment of idiopathic nephrotic syndrome in children. Lancet 1:380\u2013383","journal-title":"Lancet"},{"key":"1026_CR28","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1681\/ASN.V85824","volume":"8","author":"BM Tune","year":"1997","unstructured":"Tune BM, Mendoza SA (1997) Treatment of the idiopathic nephritic syndrome: regimens and outcomes in children and adults. J Am Soc Nephrol 8:824\u2013832","journal-title":"J Am Soc Nephrol"},{"key":"1026_CR29","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1007\/BF00857534","volume":"7","author":"R Habib","year":"1993","unstructured":"Habib R (1993) Nephrotic syndrome in the 1st year of life. Pediatr Nephrol 7:347\u2013353","journal-title":"Pediatr Nephrol"},{"key":"1026_CR30","first-page":"503","volume-title":"Pediatric nephrology","author":"C Holmberg","year":"2004","unstructured":"Holmberg C, Tryggvason K, Kestila M, Jalanko H (2004) Congenital nephrotic syndrome. In: Avner E, Harmon WE, Niaudet P (eds) Pediatric nephrology, 5th edn. Lippincott Williams & Wilkins, Baltimore, pp 503\u2013516","edition":"5"},{"key":"1026_CR31","doi-asserted-by":"publisher","first-page":"1299","DOI":"10.1016\/S0140-6736(70)91905-7","volume":"1","author":"J Churg","year":"1970","unstructured":"Churg J, Habib R, White RHR (1970) The pathology of the nephrotic syndrome in children. A report of the International Study of Kidney Disease in Children. Lancet 1:1299\u20131302","journal-title":"Lancet"},{"key":"1026_CR32","doi-asserted-by":"publisher","first-page":"S3","DOI":"10.1053\/ajkd.2003.50074","volume":"41","author":"S Klahr","year":"2003","unstructured":"Klahr S, Morrissey J (2003) Progression of chronic renal disease. Am J Kidney Dis 41:S3\u2013S7","journal-title":"Am J Kidney Dis"},{"key":"1026_CR33","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1681\/ASN.2004070593","volume":"16","author":"S Troyanov","year":"2005","unstructured":"Troyanov S, Wall CA, Miller JA, Scholey JW, Cattran DC (2005) Focal and segmental glomerulosclerosis: definition and relevance of a partial remission. J Am Soc Nephrol 16:1061\u20131068","journal-title":"J Am Soc Nephrol"},{"key":"1026_CR34","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1007\/s00467-005-2097-0","volume":"21","author":"DS Gipson","year":"2006","unstructured":"Gipson DS, Chin H, Presler TP, Jennette C, Ferris ME, Massengill S, Gibson K, Thomas DB (2006) Differential risk of remission and ESRD in childhood FSGS. Pediatr Nephrol 21:344\u2013349","journal-title":"Pediatr Nephrol"},{"key":"1026_CR35","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.1517\/14656566.6.9.1539","volume":"6","author":"A Meyrier","year":"2005","unstructured":"Meyrier A (2005) Treatment of focal segmental glomerulosclerosis. Expert Opin Pharmacother 6:1539\u20131549","journal-title":"Expert Opin Pharmacother"},{"key":"1026_CR36","doi-asserted-by":"publisher","first-page":"1779","DOI":"10.1007\/s00467-007-0505-3","volume":"22","author":"L Copelovitch","year":"2007","unstructured":"Copelovitch L, Guttenberg M, Pollak MR, Kaplan PS (2007) Renin-angiotensin axis blockade reduces proteinuria in presymptomatic patients with familial FSGS. Pediatr Nephrol 22:1779\u20131784","journal-title":"Pediatr Nephrol"},{"key":"1026_CR37","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1007\/s00467-008-0789-y","volume":"23","author":"E W\u00fchl","year":"2008","unstructured":"W\u00fchl E, Schaefer F (2008) Therapeutic strategies to slow chronic kidney disease progression. Pediatr Nephrol 23:705\u2013716","journal-title":"Pediatr Nephrol"},{"key":"1026_CR38","doi-asserted-by":"publisher","first-page":"2421","DOI":"10.1001\/jama.288.19.2421","volume":"288","author":"JT Wright Jr","year":"2003","unstructured":"Wright JT Jr, Bakris G, Greene T, Agodoa LY, Appel LJ, Charleston J, Cheek D, Douglas-Baltimore JG, Gassman J, Glassock R, Hebert L, Jamerson K, Lewis J, Phillips RA, Toto RD, Middleton JP, Rostand SG (2003) African American study of kidney disease and hypertension: effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease: results from the AASK trial. JAMA 288:2421\u20132431","journal-title":"JAMA"}],"container-title":["Pediatric Nephrology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-008-1026-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00467-008-1026-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-008-1026-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-008-1026-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,18]],"date-time":"2021-09-18T11:35:39Z","timestamp":1631964939000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00467-008-1026-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5]]},"references-count":38,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2009,5]]}},"alternative-id":["1026"],"URL":"https:\/\/doi.org\/10.1007\/s00467-008-1026-4","relation":{},"ISSN":["0931-041X","1432-198X"],"issn-type":[{"value":"0931-041X","type":"print"},{"value":"1432-198X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,5]]},"assertion":[{"value":"14 April 2008","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 September 2008","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 September 2008","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 May 2009","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}