{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T11:55:22Z","timestamp":1759146922200},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2012,3,28]],"date-time":"2012-03-28T00:00:00Z","timestamp":1332892800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Nephrol"],"published-print":{"date-parts":[[2012,8]]},"DOI":"10.1007\/s00467-012-2142-8","type":"journal-article","created":{"date-parts":[[2012,3,27]],"date-time":"2012-03-27T06:26:55Z","timestamp":1332829615000},"page":"1389-1395","source":"Crossref","is-referenced-by-count":14,"title":["Elevated serum levels of B-cell activating factor in pediatric renal transplant patients"],"prefix":"10.1007","volume":"27","author":[{"given":"Anja","family":"Lehnhardt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franziska","family":"Dunst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"van Husen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastian","family":"Loos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Oh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Eiermann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Koch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus J.","family":"Kemper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,3,28]]},"reference":[{"key":"2142_CR1","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1038\/nrneph.2010.111","volume":"6","author":"AD Kirk","year":"2010","unstructured":"Kirk AD, Turgeon NA, Iwakoshi NN (2010) B cells and transplantation tolerance. Nat Rev Nephrol 6:584\u2013593","journal-title":"Nat Rev Nephrol"},{"key":"2142_CR2","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/j.1399-3046.2008.00943.x","volume":"13","author":"MR Muorah","year":"2009","unstructured":"Muorah MR, Brogan PA, Sebire NJ, Trompeter RS, Marks SD (2009) Dense B cell infiltrates in paediatric renal transplant biopsies are predictive of allograft loss. Pediatr Transplant 13:217\u2013222","journal-title":"Pediatr Transplant"},{"key":"2142_CR3","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1111\/j.1600-6143.2006.01246.x","volume":"6","author":"A Lehnhardt","year":"2006","unstructured":"Lehnhardt A, Mengel M, Pape L, Ehrich JH, Offner G, Strehlau J (2006) Nodular B-cell aggregates associated with treatment refractory renal transplant rejection resolved by rituximab. Am J Transplant 6:847\u2013851","journal-title":"Am J Transplant"},{"key":"2142_CR4","doi-asserted-by":"crossref","first-page":"2607","DOI":"10.1111\/j.1600-6143.2008.02411.x","volume":"8","author":"V Zarkhin","year":"2008","unstructured":"Zarkhin V, Li L, Kambham N, Sigdel T, Salvatierra O, Sarwal MM (2008) A randomized, prospective trial of rituximab for acute rejection in pediatric renal transplantation. Am J Transplant 8:2607\u20132617","journal-title":"Am J Transplant"},{"key":"2142_CR5","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1600-6143.2011.03830.x","volume":"12","author":"N Kohei","year":"2012","unstructured":"Kohei N, Hirai T, Omoto K, Ishida H, Tanabe K (2012) Chronic antibody-mediated rejection is reduced by targeting B-cell immunity during an introductory period. Am J Transplant 12:469\u2013476","journal-title":"Am J Transplant"},{"key":"2142_CR6","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1126\/science.285.5425.260","volume":"285","author":"PA Moore","year":"1999","unstructured":"Moore PA, Belvedere O, Orr A, Pieri K, LaFleur DW, Feng P, Soppet D, Charters M, Gentz R, Parmelee D, Li Y, Galperina O, Giri J, Roschke V, Nardelli B, Carrell J, Sosnovtseva S, Greenfield W, Ruben SM, Olsen HS, Fikes J, Hilbert DM (1999) BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator. Science 285:260\u2013263","journal-title":"Science"},{"key":"2142_CR7","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1038\/nri844","volume":"2","author":"F Mackay","year":"2002","unstructured":"Mackay F, Browning JL (2002) BAFF: a fundamental survival factor for B cells. Nat Rev Immunol 2:465\u2013475","journal-title":"Nat Rev Immunol"},{"key":"2142_CR8","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1016\/j.humpath.2005.08.005","volume":"36","author":"SJ Rodig","year":"2005","unstructured":"Rodig SJ, Shahsafaei A, Li B, Mackay CR, Dorfman DM (2005) BAFF-R, the major B cell-activating factor receptor, is expressed on most mature B cells and B-cell lymphoproliferative disorders. Hum Pathol 36:1113\u20131119","journal-title":"Hum Pathol"},{"key":"2142_CR9","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.smim.2006.04.005","volume":"18","author":"F Mackay","year":"2006","unstructured":"Mackay F, Leung H (2006) The role of the BAFF\/APRIL system on T cell function. Semin Immunol 18:284\u2013289","journal-title":"Semin Immunol"},{"key":"2142_CR10","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1002\/1529-0131(200106)44:6<1313::AID-ART223>3.0.CO;2-S","volume":"44","author":"GS Cheema","year":"2001","unstructured":"Cheema GS, Roschke V, Hilbert DM, Stohl W (2001) Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases. Arthritis Rheum 44:1313\u20131319","journal-title":"Arthritis Rheum"},{"key":"2142_CR11","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1038\/nri2572","volume":"9","author":"F Mackay","year":"2009","unstructured":"Mackay F, Schneider P (2009) Cracking the BAFF code. Nat Rev Immunol 9:491\u2013502","journal-title":"Nat Rev Immunol"},{"key":"2142_CR12","doi-asserted-by":"crossref","first-page":"R167","DOI":"10.1186\/ar2076","volume":"8","author":"T Vallerskog","year":"2006","unstructured":"Vallerskog T, Heimburger M, Gunnarsson I, Zhou W, Wahren-Herlenius M, Trollmo C, Malmstrom V (2006) Differential effects on BAFF and APRIL levels in rituximab-treated patients with systemic lupus erythematosus and rheumatoid arthritis. Arthritis Res Ther 8:R167","journal-title":"Arthritis Res Ther"},{"key":"2142_CR13","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1002\/ajh.21328","volume":"84","author":"SM Ansell","year":"2009","unstructured":"Ansell SM, Novak AJ, Ziesmer S, Price-Troska T, LaPlant B, Dillon SR, Witzig TE (2009) Serum BLyS levels increase after rituximab as initial therapy in patients with follicular Grade 1 non-Hodgkin lymphoma. Am J Hematol 84:71\u201373","journal-title":"Am J Hematol"},{"key":"2142_CR14","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1097\/TP.0b013e3181bbba1a","volume":"88","author":"V Zarkhin","year":"2009","unstructured":"Zarkhin V, Li L, Sarwal MM (2009) BAFF may modulate the rate of B-cell repopulation after rituximab therapy for acute renal transplant rejection. Transplantation 88:1229\u20131230","journal-title":"Transplantation"},{"key":"2142_CR15","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1111\/j.1600-6143.2009.02710.x","volume":"9","author":"D Bloom","year":"2009","unstructured":"Bloom D, Chang Z, Pauly K, Kwun J, Fechner J, Hayes C, Samaniego M, Knechtle S (2009) BAFF is increased in renal transplant patients following treatment with alemtuzumab. Am J Transplant 9:1835\u20131845","journal-title":"Am J Transplant"},{"key":"2142_CR16","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1038\/nrrheum.2009.141","volume":"5","author":"T Dorner","year":"2009","unstructured":"Dorner T, Radbruch A, Burmester GR (2009) B-cell-directed therapies for autoimmune disease. Nat Rev Rheumatol 5:433\u2013441","journal-title":"Nat Rev Rheumatol"},{"key":"2142_CR17","doi-asserted-by":"crossref","first-page":"3865","DOI":"10.1182\/blood-2008-09-177840","volume":"113","author":"S Sarantopoulos","year":"2009","unstructured":"Sarantopoulos S, Stevenson KE, Kim HT, Cutler CS, Bhuiya NS, Schowalter M, Ho VT, Alyea EP, Koreth J, Blazar BR, Soiffer RJ, Antin JH, Ritz J (2009) Altered B-cell homeostasis and excess BAFF in human chronic graft-versus-host disease. Blood 113:3865\u20133874","journal-title":"Blood"},{"key":"2142_CR18","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1016\/j.transproceed.2008.10.024","volume":"41","author":"H Xu","year":"2009","unstructured":"Xu H, He X, Liu Q, Shi D, Chen Y, Zhu Y, Zhang X (2009) Abnormal high expression of B-cell activating factor belonging to the TNF superfamily (BAFF) associated with long-term outcome in kidney transplant recipients. Transplant Proc 41:1552\u20131556","journal-title":"Transplant Proc"},{"key":"2142_CR19","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1007\/s00467-003-1271-5","volume":"18","author":"G Filler","year":"2003","unstructured":"Filler G, Lepage N (2003) Should the Schwartz formula for estimation of GFR be replaced by cystatin C formula? Pediatr Nephrol 18:981\u2013985","journal-title":"Pediatr Nephrol"},{"key":"2142_CR20","doi-asserted-by":"crossref","first-page":"3013","DOI":"10.1093\/ndt\/gfm318","volume":"22","author":"C White","year":"2007","unstructured":"White C, Akbari A, Hussain N, Dinh L, Filler G, Lepage N, Knoll GA (2007) Chronic kidney disease stage in renal transplantation classification using cystatin C and creatinine-based equations. Nephrol Dial Transplant 22:3013\u20133020","journal-title":"Nephrol Dial Transplant"},{"key":"2142_CR21","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1111\/j.1399-0039.1998.tb03100.x","volume":"51","author":"A Wolpl","year":"1998","unstructured":"Wolpl A, Halder T, Kalbacher H, Neumeyer H, Siemoneit K, Goldmann SF, Eiermann TH (1998) Human monoclonal antibody with T-cell-like specificity recognizes MHC class I self-peptide presented by HLA-DR1 on activated cells. Tissue Antigens 51:258\u2013269","journal-title":"Tissue Antigens"},{"key":"2142_CR22","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/j.jaci.2003.07.003","volume":"112","author":"WT Shearer","year":"2003","unstructured":"Shearer WT, Rosenblatt HM, Gelman RS, Oyomopito R, Plaeger S, Stiehm ER, Wara DW, Douglas SD, Luzuriaga K, McFarland EJ, Yogev R, Rathore MH, Levy W, Graham BL, Spector SA (2003) Lymphocyte subsets in healthy children from birth through 18 years of age: the Pediatric AIDS Clinical Trials Group P1009 study. J Allergy Clin Immunol 112:973\u2013980","journal-title":"J Allergy Clin Immunol"},{"key":"2142_CR23","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.cyto.2008.06.001","volume":"44","author":"MR Pranzatelli","year":"2008","unstructured":"Pranzatelli MR, Tate ED, Hoefgen ER, Swan JA, Colliver JA (2008) Therapeutic down-regulation of central and peripheral B-cell-activating factor (BAFF) production in pediatric opsoclonus-myoclonus syndrome. Cytokine 44:26\u201332","journal-title":"Cytokine"},{"key":"2142_CR24","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1097\/TP.0b013e318213df29","volume":"91","author":"V Zarkhin","year":"2011","unstructured":"Zarkhin V, Lovelace PA, Li L, Hsieh SC, Sarwal MM (2011) Phenotypic evaluation of B-cell subsets after rituximab for treatment of acute renal allograft rejection in pediatric recipients. Transplantation 91:1010\u20131018","journal-title":"Transplantation"},{"key":"2142_CR25","doi-asserted-by":"crossref","first-page":"497","DOI":"10.4049\/jimmunol.1102321","volume":"188","author":"M Kreuzaler","year":"2012","unstructured":"Kreuzaler M, Rauch M, Salzer U, Birmelin J, Rizzi M, Grimbacher B, Plebani A, Lougaris V, Quinti I, Thon V, Litzman J, Schlesier M, Warnatz K, Thiel J, Rolink AG, Eibel H (2012) Soluble BAFF levels inversely correlate with peripheral B cell numbers and the expression of BAFF receptors. J Immunol 188:497\u2013503","journal-title":"J Immunol"},{"key":"2142_CR26","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1097\/TP.0b013e318166910b","volume":"85","author":"A Demirkiran","year":"2008","unstructured":"Demirkiran A, Hendrikx TK, Baan CC, van der Laan LJ (2008) Impact of immunosuppressive drugs on CD4 + CD25 + FOXP3+ regulatory T cells: does in vitro evidence translate to the clinical setting? Transplantation 85:783\u2013789","journal-title":"Transplantation"},{"key":"2142_CR27","doi-asserted-by":"crossref","first-page":"807","DOI":"10.4049\/jimmunol.173.2.807","volume":"173","author":"LG Ng","year":"2004","unstructured":"Ng LG, Sutherland AP, Newton R, Qian F, Cachero TG, Scott ML, Thompson JS, Wheway J, Chtanova T, Groom J, Sutton IJ, Xin C, Tangye SG, Kalled SL, Mackay F, Mackay CR (2004) B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells. J Immunol 173:807\u2013817","journal-title":"J Immunol"},{"key":"2142_CR28","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1093\/ndt\/gfp397","volume":"25","author":"MV Pahl","year":"2009","unstructured":"Pahl MV, Gollapudi S, Sepassi L, Gollapudi P, Elahimehr R, Vaziri ND (2009) Effect of end-stage renal disease on B-lymphocyte subpopulations, IL-7, BAFF and BAFF receptor expression. Nephrol Dial Transplant 25:205\u2013212","journal-title":"Nephrol Dial Transplant"},{"key":"2142_CR29","first-page":"422","volume":"44","author":"TA Riccobene","year":"2003","unstructured":"Riccobene TA, Miceli RC, Lincoln C, Knight Y, Meadows J, Stabin MG, Sung C (2003) Rapid and specific targeting of 125I-labeled B lymphocyte stimulator to lymphoid tissues and B cell tumors in mice. J Nucl Med 44:422\u2013433","journal-title":"J Nucl Med"},{"key":"2142_CR30","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1177\/089686080002000628","volume":"20","author":"AH Bouts","year":"2000","unstructured":"Bouts AH, Out TA, Schroder CH, Monnens LA, Nauta J, Krediet RT, Davin JC (2000) Characteristics of peripheral and peritoneal white blood cells in children with chronic renal failure, dialyzed or not. Perit Dial Int 20:748\u2013756","journal-title":"Perit Dial Int"},{"key":"2142_CR31","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.cellimm.2009.10.004","volume":"261","author":"M Thorn","year":"2009","unstructured":"Thorn M, Lewis RH, Mumbey-Wafula A, Kantrowitz S, Spatz LA (2009) BAFF overexpression promotes anti-dsDNA B-cell maturation and antibody secretion. Cell Immunol 261:9\u201322","journal-title":"Cell Immunol"},{"key":"2142_CR32","doi-asserted-by":"crossref","first-page":"1648","DOI":"10.1097\/TP.0b013e3181735723","volume":"85","author":"O Thaunat","year":"2008","unstructured":"Thaunat O, Patey N, Gautreau C, Lechaton S, Fremeaux-Bacchi V, Dieu-Nosjean MC, Cassuto-Viguier E, Legendre C, Delahousse M, Lang P, Michel JB, Nicoletti A (2008) B cell survival in intragraft tertiary lymphoid organs after rituximab therapy. Transplantation 85:1648\u20131653","journal-title":"Transplantation"},{"key":"2142_CR33","author":"W Stohl","year":"2012","unstructured":"Stohl W, Hiepe F, Latinis KM, Thomas M, Scheinberg MA, Clarke A, Aranow C, Wellborne FR, Abud-Mendoza C, Hough DR, Pineda L, Migone TS, Zhong ZJ, Freimuth WW, Chatham WW (2012) Belimumab reduces autoantibodies, normalizes low complement, and reduces select B-cell populations in patients with systemic lupus erythematosus. Arthritis Rheum doi: 10.1002\/art.34400","journal-title":"Arthritis Rheum"}],"container-title":["Pediatric Nephrology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-012-2142-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00467-012-2142-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-012-2142-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,4]],"date-time":"2020-07-04T22:32:13Z","timestamp":1593901933000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00467-012-2142-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3,28]]},"references-count":33,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["2142"],"URL":"https:\/\/doi.org\/10.1007\/s00467-012-2142-8","relation":{},"ISSN":["0931-041X","1432-198X"],"issn-type":[{"value":"0931-041X","type":"print"},{"value":"1432-198X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,3,28]]}}}