{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T03:09:15Z","timestamp":1791860955560,"version":"4.3.4"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2012,10,5]],"date-time":"2012-10-05T00:00:00Z","timestamp":1349395200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Nephrol"],"published-print":{"date-parts":[[2013,9]]},"DOI":"10.1007\/s00467-012-2321-7","type":"journal-article","created":{"date-parts":[[2012,10,4]],"date-time":"2012-10-04T03:03:50Z","timestamp":1349319830000},"page":"1757-1761","source":"Crossref","is-referenced-by-count":12,"title":["A translational approach to congenital non-obstructive hydronephrosis"],"prefix":"10.1007","volume":"28","author":[{"given":"Robyn P.","family":"Thom","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norman D.","family":"Rosenblum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,10,5]]},"reference":[{"key":"2321_CR1","doi-asserted-by":"crossref","first-page":"F31","DOI":"10.1136\/fn.76.1.F31","volume":"76","author":"JA Dudley","year":"1997","unstructured":"Dudley JA, Haworth JM, McGraw ME, Frank JD, Tizard EJ (1997) Clinical relevance and implications of antenatal hydronephrosis. Arch Dis Child Fetal Neonatal Ed 76:F31\u2013F34","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"2321_CR2","first-page":"1181","volume":"146","author":"CE Johnson","year":"1992","unstructured":"Johnson CE, Elder JS, Judge NE, Adeeb FN, Grisoni ER, Fattlar DC (1992) The accuracy of antenatal ultrasonography in identifying renal abnormalities. Am J Dis Child 146:1181\u20131184","journal-title":"Am J Dis Child"},{"key":"2321_CR3","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1172\/JCI45523","volume":"121","author":"JE Cain","year":"2011","unstructured":"Cain JE, Islam E, Haxho F, Blake J, Rosenblum ND (2011) GLI3 repressor controls functional development of the mouse ureter. J Clin Invest 121:1199\u20131206","journal-title":"J Clin Invest"},{"key":"2321_CR4","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1111\/j.1749-6632.1998.tb08932.x","volume":"847","author":"H Grandjean","year":"1998","unstructured":"Grandjean H, Larroque D, Levi S (1998) Sensitivity of routine ultrasound screening of pregnancies in the Eurofetus database. The Eurofetus Team. Ann N Y Acad Sci 847:118\u2013124","journal-title":"Ann N Y Acad Sci"},{"key":"2321_CR5","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1002\/uog.935","volume":"22","author":"S Levi","year":"2003","unstructured":"Levi S (2003) Mass screening for fetal malformations: the Eurofetus study. Ultrasound Obstet Gynecol 22:555\u2013558","journal-title":"Ultrasound Obstet Gynecol"},{"key":"2321_CR6","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1148\/radiology.178.1.1984303","volume":"178","author":"J Mandell","year":"1991","unstructured":"Mandell J, Blyth BR, Peters CA, Retik AB, Estroff JA, Benacerraf BR (1991) Structural genitourinary defects detected in utero. Radiology 178:193\u2013196","journal-title":"Radiology"},{"key":"2321_CR7","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1046\/j.1464-4096.2001.woodward.2578.x","volume":"89","author":"M Woodward","year":"2002","unstructured":"Woodward M, Frank D (2002) Postnatal management of antenatal hydronephrosis. BJU Int 89:149\u2013156","journal-title":"BJU Int"},{"key":"2321_CR8","volume-title":"Campbell\u2019s urology","author":"PC Walsh","year":"2002","unstructured":"Walsh PC, Retik AB, Vaughan ED, Wein AJ, Kavoussi LR, Novick AC, Partin AW, Peters CA (2002) Campbell\u2019s urology, 8th edn, Saunders, Philadelphia","edition":"8"},{"key":"2321_CR9","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1001\/archpedi.158.1.38","volume":"158","author":"AM Cheng","year":"2004","unstructured":"Cheng AM, Phan V, Geary DF, Rosenblum ND (2004) Outcome of isolated antenatal hydronephrosis. Arch Pediatr Adolesc Med 158:38\u201340","journal-title":"Arch Pediatr Adolesc Med"},{"key":"2321_CR10","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/S0022-5347(17)38842-0","volume":"142","author":"CA Peters","year":"1989","unstructured":"Peters CA, Mandell J, Lebowitz RL, Colodny AH, Bauer SB, Hendren WH, Retik AB (1989) Congenital obstructed megaureters in early infancy: diagnosis and treatment. J Urol 142:641\u2013645, discussion 667\u2013648","journal-title":"J Urol"},{"key":"2321_CR11","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1172\/JCI46400","volume":"121","author":"D Herzlinger","year":"2011","unstructured":"Herzlinger D (2011) Upper urinary tract pacemaker cells join the GLI club. J Clin Invest 121:836\u2013838","journal-title":"J Clin Invest"},{"key":"2321_CR12","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0092-8674(00)81960-1","volume":"98","author":"CH Chen","year":"1999","unstructured":"Chen CH, von Kessler DP, Park W, Wang B, Ma Y, Beachy PA (1999) Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression. Cell 98:305\u2013316","journal-title":"Cell"},{"key":"2321_CR13","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1016\/S1097-2765(03)00426-X","volume":"12","author":"L Lum","year":"2003","unstructured":"Lum L, Zhang C, Oh S, Mann RK, von Kessler DP, Taipale J, Weis-Garcia F, Gong R, Wang B, Beachy PA (2003) Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2. Mol Cell 12:1261\u20131274","journal-title":"Mol Cell"},{"key":"2321_CR14","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.devcel.2005.01.001","volume":"8","author":"W Zhang","year":"2005","unstructured":"Zhang W, Zhao Y, Tong C, Wang G, Wang B, Jia J, Jiang J (2005) Hedgehog-regulated Costal2-kinase complexes control phosphorylation and proteolytic processing of Cubitus interruptus. Dev Cell 8:267\u2013278","journal-title":"Dev Cell"},{"key":"2321_CR15","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1242\/dev.02220","volume":"133","author":"MC Hu","year":"2006","unstructured":"Hu MC, Mo R, Bhella S, Wilson CW, Chuang PT, Hui CC, Rosenblum ND (2006) GLI3-dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesis. Development 133:569\u2013578","journal-title":"Development"},{"key":"2321_CR16","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/ng0397-266","volume":"15","author":"S Kang","year":"1997","unstructured":"Kang S, Graham JM Jr, Olney AH, Biesecker LG (1997) GLI3 frameshift mutations cause autosomal dominant Pallister-Hall syndrome. Nat Genet 15:266\u2013268","journal-title":"Nat Genet"},{"key":"2321_CR17","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1146\/annurev.biochem.70.1.503","volume":"70","author":"CM Pickart","year":"2001","unstructured":"Pickart CM (2001) Mechanisms underlying ubiquitination. Annu Rev Biochem 70:503\u2013533","journal-title":"Annu Rev Biochem"},{"key":"2321_CR18","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1073\/pnas.95.5.2349","volume":"95","author":"Y Chen","year":"1998","unstructured":"Chen Y, Gallaher N, Goodman RH, Smolik SM (1998) Protein kinase A directly regulates the activity and proteolysis of cubitus interruptus. Proc Natl Acad Sci U S A 95:2349\u20132354","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2321_CR19","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1073\/pnas.0509927103","volume":"103","author":"B Wang","year":"2006","unstructured":"Wang B, Li Y (2006) Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing. Proc Natl Acad Sci U S A 103:33\u201338","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2321_CR20","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1038\/nature07884","volume":"458","author":"TA Soucy","year":"2009","unstructured":"Soucy TA, Smith PG, Milhollen MA, Berger AJ, Gavin JM, Adhikari S, Brownell JE, Burke KE, Cardin DP, Critchley S, Cullis CA, Doucette A, Garnsey JJ, Gaulin JL, Gershman RE, Lublinsky AR, McDonald A, Mizutani H, Narayanan U, Olhava EJ, Peluso S, Rezaei M, Sintchak MD, Talreja T, Thomas MP, Traore T, Vyskocil S, Weatherhead GS, Yu J, Zhang J, Dick LR, Claiborne CF, Rolfe M, Bolen JB, Langston SP (2009) An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer. Nature 458:732\u2013736","journal-title":"Nature"},{"key":"2321_CR21","doi-asserted-by":"crossref","first-page":"e7313","DOI":"10.1371\/journal.pone.0007313","volume":"4","author":"JE Cain","year":"2009","unstructured":"Cain JE, Islam E, Haxho F, Chen L, Bridgewater D, Nieuwenhuis E, Hui CC, Rosenblum ND (2009) GLI3 repressor controls nephron number via regulation of Wnt11 and Ret in ureteric tip cells. PLoS One 4:e7313","journal-title":"PLoS One"},{"key":"2321_CR22","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1080\/10611860600612953","volume":"14","author":"V Mishra","year":"2006","unstructured":"Mishra V, Mahor S, Rawat A, Gupta PN, Dubey P, Khatri K, Vyas SP (2006) Targeted brain delivery of AZT via transferrin anchored pegylated albumin nanoparticles. J Drug Target 14:45\u201353","journal-title":"J Drug Target"}],"container-title":["Pediatric Nephrology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-012-2321-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00467-012-2321-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-012-2321-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,4]],"date-time":"2019-07-04T11:37:49Z","timestamp":1562240269000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00467-012-2321-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10,5]]},"references-count":22,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["2321"],"URL":"https:\/\/doi.org\/10.1007\/s00467-012-2321-7","relation":{},"ISSN":["0931-041X","1432-198X"],"issn-type":[{"value":"0931-041X","type":"print"},{"value":"1432-198X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10,5]]}}}