{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T09:45:27Z","timestamp":1768470327657,"version":"3.49.0"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2015,4,26]],"date-time":"2015-04-26T00:00:00Z","timestamp":1430006400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Nephrol"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1007\/s00467-015-3097-3","type":"journal-article","created":{"date-parts":[[2015,4,25]],"date-time":"2015-04-25T12:18:57Z","timestamp":1429964337000},"page":"1879-1888","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Risk factors for acute kidney injury during aminoglycoside therapy in patients with cystic fibrosis"],"prefix":"10.1007","volume":"30","author":[{"given":"Kevin J.","family":"Downes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neha R.","family":"Patil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marepalli B.","family":"Rao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajesh","family":"Koralkar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William T.","family":"Harris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John P.","family":"Clancy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stuart L.","family":"Goldstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David J.","family":"Askenazi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,4,26]]},"reference":[{"key":"3097_CR1","doi-asserted-by":"crossref","first-page":"153","DOI":"10.2174\/1568005043340858","volume":"4","author":"F Rougier","year":"2004","unstructured":"Rougier F, Claude D, Maurin M, Maire P (2004) Aminoglycoside nephrotoxicity. Curr Drug Targets Infect Disord 4:153\u2013162","journal-title":"Curr Drug Targets Infect Disord"},{"key":"3097_CR2","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1093\/ndt\/gfq375","volume":"26","author":"M Zappitelli","year":"2011","unstructured":"Zappitelli M, Moffett BS, Hyder A, Goldstein SL (2011) Acute kidney injury in non-critically ill children treated with aminoglycoside antibiotics in a tertiary healthcare centre: a retrospective cohort study. Nephrol Dial Transplant 26:144\u2013150","journal-title":"Nephrol Dial Transplant"},{"key":"3097_CR3","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1038\/sj.ki.5000032","volume":"69","author":"DJ Askenazi","year":"2006","unstructured":"Askenazi DJ, Feig DI, Graham NM, Hui-Stickle S, Goldstein SL (2006) 3\u20135\u00a0year longitudinal follow-up of pediatric patients after acute renal failure. Kidney Int 69:184\u2013189","journal-title":"Kidney Int"},{"key":"3097_CR4","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1007\/s00467-003-1186-1","volume":"18","author":"CL Abitbol","year":"2003","unstructured":"Abitbol CL, Bauer CR, Montane B, Chandar J, Duara S, Zilleruelo G (2003) Long-term follow-up of extremely low birth weight infants with neonatal renal failure. Pediatr Nephrol 18:887\u2013893","journal-title":"Pediatr Nephrol"},{"key":"3097_CR5","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1038\/ki.2011.379","volume":"81","author":"SG Coca","year":"2012","unstructured":"Coca SG, Singanamala S, Parikh CR (2012) Chronic kidney disease after acute kidney injury: a systematic review and meta-analysis. Kidney Int 81:442\u2013448","journal-title":"Kidney Int"},{"key":"3097_CR6","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.healun.2011.08.016","volume":"31","author":"E Wehbe","year":"2012","unstructured":"Wehbe E, Brock R, Budev M, Xu M, Demirjian S, Schreiber MJ, Stephany B (2012) Short-term and long-term outcomes of acute kidney injury after lung transplantation. J Heart Lung Transplant 31:244\u2013251","journal-title":"J Heart Lung Transplant"},{"key":"3097_CR7","doi-asserted-by":"crossref","first-page":"856","DOI":"10.2215\/CJN.08110910","volume":"6","author":"BS Moffett","year":"2011","unstructured":"Moffett BS, Goldstein SL (2011) Acute kidney injury and increasing nephrotoxic-medication exposure in noncritically-ill children. Clin J Am Soc Nephrol 6:856\u2013863","journal-title":"Clin J Am Soc Nephrol"},{"key":"3097_CR8","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/j.jpeds.2014.04.058","volume":"165","author":"S Menon","year":"2014","unstructured":"Menon S, Kirkendall ES, Nguyen H, Goldstein SL (2014) Acute kidney injury associated with high nephrotoxic medication exposure leads to chronic kidney disease after 6\u00a0months. J Pediatr 165:522\u2013527, e522","journal-title":"J Pediatr"},{"key":"3097_CR9","first-page":"37","volume":"46","author":"AM Contreras","year":"1994","unstructured":"Contreras AM, Ramirez M, Cueva L, Alvarez S, de Loza R, Gamba G (1994) Low serum albumin and the increased risk of amikacin nephrotoxicity. Rev Invest Clin 46:37\u201343","journal-title":"Rev Invest Clin"},{"key":"3097_CR10","first-page":"93","volume":"42","author":"J Cortes","year":"1990","unstructured":"Cortes J, Gamba G, Contreras A, Pena JC (1990) Amikacin nephrotoxicity in patients with chronic liver disease. Rev Invest Clin 42:93\u201398","journal-title":"Rev Invest Clin"},{"key":"3097_CR11","first-page":"204","volume":"42","author":"G Gamba","year":"1990","unstructured":"Gamba G, Contreras AM, Cortes J, Nares F, Santiago Y, Espinosa A, Bobadilla J, Jimenez Sanchez G, Lopez G, Valadez A (1990) Hypoalbuminemia as a risk factor for amikacin nephrotoxicity. Rev Invest Clin 42:204\u2013209","journal-title":"Rev Invest Clin"},{"key":"3097_CR12","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/0140-6736(93)90137-6","volume":"341","author":"JM Prins","year":"1993","unstructured":"Prins JM, Buller HR, Kuijper EJ, Tange RA, Speelman P (1993) Once versus thrice daily gentamicin in patients with serious infections. Lancet 341:335\u2013339","journal-title":"Lancet"},{"key":"3097_CR13","doi-asserted-by":"crossref","first-page":"493","DOI":"10.2165\/00003088-200342050-00007","volume":"42","author":"F Rougier","year":"2003","unstructured":"Rougier F, Ducher M, Maurin M, Corvaisier S, Claude D, Jelliffe R, Maire P (2003) Aminoglycoside dosages and nephrotoxicity: quantitative relationships. Clin Pharmacokinet 42:493\u2013500","journal-title":"Clin Pharmacokinet"},{"key":"3097_CR14","doi-asserted-by":"crossref","first-page":"2494","DOI":"10.1128\/AAC.40.11.2494","volume":"40","author":"JM Prins","year":"1996","unstructured":"Prins JM, Weverling GJ, de Blok K, van Ketel RJ, Speelman P (1996) Validation and nephrotoxicity of a simplified once-daily aminoglycoside dosing schedule and guidelines for monitoring therapy. Antimicrob Agents Chemother 40:2494\u20132499","journal-title":"Antimicrob Agents Chemother"},{"key":"3097_CR15","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1681\/ASN.V4181","volume":"4","author":"DJ Leehey","year":"1993","unstructured":"Leehey DJ, Braun BI, Tholl DA, Chung LS, Gross CA, Roback JA, Lentino JR (1993) Can pharmacokinetic dosing decrease nephrotoxicity associated with aminoglycoside therapy. J Am Soc Nephrol 4:81\u201390","journal-title":"J Am Soc Nephrol"},{"key":"3097_CR16","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1093\/infdis\/167.1.173","volume":"167","author":"JS Bertino Jr","year":"1993","unstructured":"Bertino JS Jr, Booker LA, Franck PA, Jenkins PL, Franck KR, Nafziger AN (1993) Incidence of and significant risk factors for aminoglycoside-associated nephrotoxicity in patients dosed by using individualized pharmacokinetic monitoring. J Infect Dis 167:173\u2013179","journal-title":"J Infect Dis"},{"key":"3097_CR17","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1002\/j.1875-9114.1990.tb03566.x","volume":"10","author":"DJ Pauly","year":"1990","unstructured":"Pauly DJ, Musa DM, Lestico MR, Lindstrom MJ, Hetsko CM (1990) Risk of nephrotoxicity with combination vancomycin-aminoglycoside antibiotic therapy. Pharmacotherapy 10:378\u2013382","journal-title":"Pharmacotherapy"},{"key":"3097_CR18","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1128\/AAC.43.7.1549","volume":"43","author":"MJ Rybak","year":"1999","unstructured":"Rybak MJ, Abate BJ, Kang SL, Ruffing MJ, Lerner SA, Drusano GL (1999) Prospective evaluation of the effect of an aminoglycoside dosing regimen on rates of observed nephrotoxicity and ototoxicity. Antimicrob Agents Chemother 43:1549\u20131555","journal-title":"Antimicrob Agents Chemother"},{"key":"3097_CR19","doi-asserted-by":"crossref","first-page":"2887","DOI":"10.1128\/AAC.01430-08","volume":"53","author":"JF Oliveira","year":"2009","unstructured":"Oliveira JF, Silva CA, Barbieri CD, Oliveira GM, Zanetta DM, Burdmann EA (2009) Prevalence and risk factors for aminoglycoside nephrotoxicity in intensive care units. Antimicrob Agents Chemother 53:2887\u20132891","journal-title":"Antimicrob Agents Chemother"},{"key":"3097_CR20","doi-asserted-by":"crossref","first-page":"17","DOI":"10.4103\/2229-5151.79277","volume":"1","author":"AT Gerlach","year":"2011","unstructured":"Gerlach AT, Stawicki SP, Cook CH, Murphy C (2011) Risk factors for aminoglycoside-associated nephrotoxicity in surgical intensive care unit patients. Int J Crit Illn Inj Sci 1:17\u201321","journal-title":"Int J Crit Illn Inj Sci"},{"key":"3097_CR21","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.jcf.2005.05.017","volume":"4","author":"M Al-Aloul","year":"2005","unstructured":"Al-Aloul M, Miller H, Stockton P, Ledson MJ, Walshaw MJ (2005) Acute renal failure in CF patients chronically infected by the Liverpool epidemic Pseudomonas aeruginosa strain (LES). J Cyst Fibros 4:197\u2013201","journal-title":"J Cyst Fibros"},{"key":"3097_CR22","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1136\/thx.2006.067595","volume":"62","author":"C Bertenshaw","year":"2007","unstructured":"Bertenshaw C, Watson AR, Lewis S, Smyth A (2007) Survey of acute renal failure in patients with cystic fibrosis in the UK. Thorax 62:541\u2013545","journal-title":"Thorax"},{"key":"3097_CR23","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1136\/thx.2007.088757","volume":"63","author":"A Smyth","year":"2008","unstructured":"Smyth A, Lewis S, Bertenshaw C, Choonara I, McGaw J, Watson A (2008) Case\u2013control study of acute renal failure in patients with cystic fibrosis in the UK. Thorax 63:532\u2013535","journal-title":"Thorax"},{"key":"3097_CR24","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1002\/ppul.20138","volume":"39","author":"M Al-Aloul","year":"2005","unstructured":"Al-Aloul M, Miller H, Alapati S, Stockton PA, Ledson MJ, Walshaw MJ (2005) Renal impairment in cystic fibrosis patients due to repeated intravenous aminoglycoside use. Pediatr Pulmonol 39:15\u201320","journal-title":"Pediatr Pulmonol"},{"key":"3097_CR25","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1111\/j.1600-6143.2005.00930.x","volume":"5","author":"SP Hmiel","year":"2005","unstructured":"Hmiel SP, Beck AM, de la Morena MT, Sweet S (2005) Progressive chronic kidney disease after pediatric lung transplantation. Am J Transplant 5:1739\u20131747","journal-title":"Am J Transplant"},{"key":"3097_CR26","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1038\/kisup.2011.32","volume":"2","author":"JA Kellum","year":"2012","unstructured":"Kellum JA (2012) KDIGO clinical practice guideline for acute kidney injury. Kidney Int Suppl 2:19\u201336","journal-title":"Kidney Int Suppl"},{"key":"3097_CR27","unstructured":"Elin RJ (2011) Appendix: Reference intervals and laboratory values. In: Goldman L, Schafer AI (eds) Goldman\u2019s Cecil medicine, 24th edn. Saunders Elsevier, Philadelphia, pp 2558\u20132569"},{"key":"3097_CR28","doi-asserted-by":"crossref","unstructured":"Arcara KM (2012) Blood chemistries and body fluids. In: Johns Hopkins Hospital, Arcara KM, Tschudy M (eds) The Harriet Lane handbook, 19th edn. Elsevier\/Mosby, Philadelphia, pp 639\u2013650","DOI":"10.1016\/B978-0-323-07942-6.00027-8"},{"key":"3097_CR29","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1017\/S1368980008002401","volume":"12","author":"E McLean","year":"2009","unstructured":"McLean E, Cogswell M, Egli I, Wojdyla D, de Benoist B (2009) Worldwide prevalence of anaemia, WHO vitamin and mineral nutrition information system, 1993\u20132005. Public Health Nutr 12:444\u2013454","journal-title":"Public Health Nutr"},{"key":"3097_CR30","first-page":"1","volume":"11","author":"RJ Kuczmarski","year":"2002","unstructured":"Kuczmarski RJ, Ogden CL, Guo SS, Grummer-Strawn LM, Flegal KM, Mei Z, Wei R, Curtin LR, Roche AF, Johnson CL (2002) 2000 CDC growth charts for the United States: methods and development. Vital Health Stat 11:1\u2013190","journal-title":"Vital Health Stat"},{"key":"3097_CR31","unstructured":"Lexicomp\u00ae (2009) Drug information handbook. Lexi-Comp, Inc., Hudson"},{"key":"3097_CR32","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1681\/ASN.2008030287","volume":"20","author":"GJ Schwartz","year":"2009","unstructured":"Schwartz GJ, Munoz A, Schneider MF, Mak RH, Kaskel F, Warady BA, Furth SL (2009) New equations to estimate GFR in children with CKD. J Am Soc Nephrol 20:629\u2013637","journal-title":"J Am Soc Nephrol"},{"key":"3097_CR33","doi-asserted-by":"crossref","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","volume":"150","author":"AS Levey","year":"2009","unstructured":"Levey AS, Stevens LA, Schmid CH, Zhang YL, Castro AF 3rd, Feldman HI, Kusek JW, Eggers P, Van Lente F, Greene T, Coresh J (2009) A new equation to estimate glomerular filtration rate. Ann Intern Med 150:604\u2013612","journal-title":"Ann Intern Med"},{"key":"3097_CR34","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","volume":"42","author":"PA Harris","year":"2009","unstructured":"Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG (2009) Research electronic data capture (REDCap)\u2013a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform 42:377\u2013381","journal-title":"J Biomed Inform"},{"issue":"Suppl 1","key":"3097_CR35","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/j.1744-9987.2011.00920.x","volume":"15","author":"R Kaseda","year":"2011","unstructured":"Kaseda R, Hosojima M, Sato H, Saito A (2011) Role of megalin and cubilin in the metabolism of vitamin D(3). Ther Apher Dial 15(Suppl 1):14\u201317","journal-title":"Ther Apher Dial"},{"key":"3097_CR36","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.jconrel.2003.12.005","volume":"95","author":"A Watanabe","year":"2004","unstructured":"Watanabe A, Nagai J, Adachi Y, Katsube T, Kitahara Y, Murakami T, Takano M (2004) Targeted prevention of renal accumulation and toxicity of gentamicin by aminoglycoside binding receptor antagonists. J Control Release 95:423\u2013433","journal-title":"J Control Release"},{"key":"3097_CR37","first-page":"11","volume":"119","author":"DG Maki","year":"1992","unstructured":"Maki DG, Fox BC, Kuntz J, Sollinger HW, Belzer FO (1992) A prospective, randomized, double-blind study of trimethoprim-sulfamethoxazole for prophylaxis of infection in renal transplantation. Side effects of trimethoprim-sulfamethoxazole, interaction with cyclosporine. J Lab Clin Med 119:11\u201324","journal-title":"J Lab Clin Med"},{"key":"3097_CR38","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1093\/jac\/dks030","volume":"67","author":"TN Fraser","year":"2012","unstructured":"Fraser TN, Avellaneda AA, Graviss EA, Musher DM (2012) Acute kidney injury associated with trimethoprim\/sulfamethoxazole. J Antimicrob Chemother 67:1271\u20131277","journal-title":"J Antimicrob Chemother"},{"key":"3097_CR39","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1177\/135965350200700307","volume":"7","author":"M Araujo de","year":"2002","unstructured":"de Araujo M, Seguro AC (2002) Trimethoprim-sulfamethoxazole (TMP\/SMX) potentiates indinavir nephrotoxicity. Antivir Ther 7:181\u2013184","journal-title":"Antivir Ther"},{"key":"3097_CR40","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/S0140-6736(05)70798-4","volume":"365","author":"A Smyth","year":"2005","unstructured":"Smyth A, Tan KH, Hyman-Taylor P, Mulheran M, Lewis S, Stableforth D, Prof Knox A (2005) Once versus three-times daily regimens of tobramycin treatment for pulmonary exacerbations of cystic fibrosis\u2013the TOPIC study: a randomised controlled trial. Lancet 365:573\u2013578","journal-title":"Lancet"}],"container-title":["Pediatric Nephrology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-015-3097-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00467-015-3097-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-015-3097-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,8]],"date-time":"2024-06-08T16:17:19Z","timestamp":1717863439000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00467-015-3097-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,26]]},"references-count":40,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["3097"],"URL":"https:\/\/doi.org\/10.1007\/s00467-015-3097-3","relation":{},"ISSN":["0931-041X","1432-198X"],"issn-type":[{"value":"0931-041X","type":"print"},{"value":"1432-198X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,26]]}}}