{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T11:20:19Z","timestamp":1790508019629,"version":"4.1.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2015,9,3]],"date-time":"2015-09-03T00:00:00Z","timestamp":1441238400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Nephrol"],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1007\/s00467-015-3174-7","type":"journal-article","created":{"date-parts":[[2015,9,2]],"date-time":"2015-09-02T13:17:28Z","timestamp":1441199848000},"page":"425-434","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Long-term outcome of idiopathic steroid-resistant nephrotic syndrome in children"],"prefix":"10.1007","volume":"31","author":[{"given":"Aya","family":"Inaba","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuko","family":"Hamasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Ishikura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riku","family":"Hamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoyuki","family":"Sakai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Hataya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumiyo","family":"Komaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuji","family":"Kaneko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaaki","family":"Mori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masataka","family":"Honda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,9,3]]},"reference":[{"key":"3174_CR1","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/BF00862503","volume":"4","author":"SA Mendoza","year":"1990","unstructured":"Mendoza SA, Reznik VM, Griswold WR, Krensky AM, Yorgin PD, Tune BM (1990) Treatment of steroid-resistant focal segmental glomerulosclerosis with pulse methylprednisolone and alkylating agents. Pediatr Nephrol 4:303\u2013307","journal-title":"Pediatr Nephrol"},{"key":"3174_CR2","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1053\/ajkd.1998.v32.pm9669427","volume":"32","author":"DC Cattran","year":"1998","unstructured":"Cattran DC, Rao P (1998) Long-term outcome in children and adults with classic focal segmental glomerulosclerosis. Am J Kidney Dis 32:72\u201379","journal-title":"Am J Kidney Dis"},{"key":"3174_CR3","first-page":"84","volume":"43","author":"BM Tune","year":"1995","unstructured":"Tune BM, Kirpekar R, Sibley RK, Reznik VM, Griswold WR, Mendoza SA (1995) Intravenous methylprednisolone and oral alkylating agent therapy of prednisone-resistant pediatric focal segmental glomerulosclerosis: a long-term follow-up. Clin Nephrol 43:84\u201388","journal-title":"Clin Nephrol"},{"key":"3174_CR4","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1001\/archpedi.1988.02150090083029","volume":"142","author":"EH Garin","year":"1988","unstructured":"Garin EH, Orak JK, Hiott KL, Sutherland SE (1988) Cyclosporine therapy for steroid-resistant nephrotic syndrome. A controlled study. Am J Dis Child 142:985\u2013988","journal-title":"Am J Dis Child"},{"key":"3174_CR5","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1038\/ki.1993.194","volume":"43","author":"C Ponticelli","year":"1993","unstructured":"Ponticelli C, Rizzoni G, Edefonti A, Altieri P, Rivolta E, Rinaldi S, Ghio L, Lusvarghi E, Gusmano R, Locatelli F, Pasquali S, Castellani A, Casa-Alberighi OD (1993) A randomized trial of cyclosporine in steroid-resistant idiopathic nephrotic syndrome. Kidney Int 43:1377\u20131384","journal-title":"Kidney Int"},{"key":"3174_CR6","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1681\/ASN.V7156","volume":"7","author":"KV Lieberman","year":"1996","unstructured":"Lieberman KV, Tejani A (1996) A randomized double-blind placebo-controlled trial of cyclosporine in steroid-resistant idiopathic focal segmental glomerulosclerosis in children. J Am Soc Nephrol 7:56\u201363","journal-title":"J Am Soc Nephrol"},{"key":"3174_CR7","doi-asserted-by":"crossref","first-page":"2177","DOI":"10.1007\/s00467-009-1264-0","volume":"24","author":"Y Hamasaki","year":"2009","unstructured":"Hamasaki Y, Yoshikawa N, Hattori S, Sasaki S, Iijima K, Nakanishi K, Matsuyama T, Ishikura K, Yata N, Kaneko T, Honda M (2009) Cyclosporine and steroid therapy in children with steroid-resistant nephrotic syndrome. Pediatr Nephrol 24:2177\u20132185","journal-title":"Pediatr Nephrol"},{"key":"3174_CR8","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1007\/s10157-014-1030-x","volume":"19","author":"K Ishikura","year":"2015","unstructured":"Ishikura K, Matsumoto S, Sako M, Tsuruga K, Nakanishi K, Kamei K, Saito H, Fujinaga S, Hamasaki Y, Chikamoto H, Ohtsuka Y, Komatsu Y, Ohta T, Nagai T, Kaito H, Kondo S, Ikezumi Y, Tanaka S, Kaku Y, Iijima K (2015) Clinical practice guideline for pediatric idiopathic nephrotic syndrome 2013: medical therapy. Clin Exp Nephrol 19:6\u201333","journal-title":"Clin Exp Nephrol"},{"key":"3174_CR9","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1542\/peds.58.2.259","volume":"58","author":"GJ Schwartz","year":"1976","unstructured":"Schwartz GJ, Haycock GB, Edelmann CM Jr, Spitzer A (1976) A simple estimate of glomerular filtration rate in children derived from body length and plasma creatinine. Pediatrics 58:259\u2013263","journal-title":"Pediatrics"},{"key":"3174_CR10","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1053\/j.ajkd.2008.12.034","volume":"53","author":"S Matsuo","year":"2009","unstructured":"Matsuo S, Imai E, Horio M, Yasuda Y, Tomita K, Nitta K, Yamagata K, Tomino Y, Yokoyama H, Hishida A (2009) Revised equations for estimated GFR from serum creatinine in Japan. Am J Kidney Dis 53:982\u2013992","journal-title":"Am J Kidney Dis"},{"key":"3174_CR11","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1007\/s00467-004-1584-z","volume":"19","author":"K Mori","year":"2004","unstructured":"Mori K, Honda M, Ikeda M (2004) Efficacy of methylprednisolone pulse therapy in steroid-resistant nephrotic syndrome. Pediatr Nephrol 19:1232\u20131236","journal-title":"Pediatr Nephrol"},{"key":"3174_CR12","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1007\/s00467-008-0794-1","volume":"23","author":"C Plank","year":"2008","unstructured":"Plank C, Kalb V, Hinkes B, Hildebrandt F, Gefeller O, Rascher W (2008) Cyclosporin A is superior to cyclophosphamide in children with steroid-resistant nephrotic syndrome-a randomized controlled multicentre trial by the Arbeitsgemeinschaft fur Padiatrische Nephrologie. Pediatr Nephrol 23:1483\u20131493","journal-title":"Pediatr Nephrol"},{"key":"3174_CR13","doi-asserted-by":"crossref","first-page":"2183","DOI":"10.1093\/ndt\/gfm092","volume":"22","author":"JH Ehrich","year":"2007","unstructured":"Ehrich JH, Geerlings C, Zivicnjak M, Franke D, Geerlings H, Gellermann J (2007) Steroid-resistant idiopathic childhood nephrosis: overdiagnosed and undertreated. Nephrol Dial Transplant 22:2183\u20132193","journal-title":"Nephrol Dial Transplant"},{"key":"3174_CR14","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1053\/j.ajkd.2008.11.033","volume":"53","author":"S Choudhry","year":"2009","unstructured":"Choudhry S, Bagga A, Hari P, Sharma S, Kalaivani M, Dinda A (2009) Efficacy and safety of tacrolimus versus cyclosporine in children with steroid-resistant nephrotic syndrome: a randomized controlled trial. Am J Kidney Dis 53:760\u2013769","journal-title":"Am J Kidney Dis"},{"key":"3174_CR15","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1007\/s00467-009-1138-5","volume":"24","author":"D Mekahli","year":"2009","unstructured":"Mekahli D, Liutkus A, Ranchin B, Yu A, Bessenay L, Girardin E, Van Damme-Lombaerts R, Palcoux JB, Cachat F, Lavocat MP, Bourdat-Michel G, Nobili F, Cochat P (2009) Long-term outcome of idiopathic steroid-resistant nephrotic syndrome: a multicenter study. Pediatr Nephrol 24:1525\u20131532","journal-title":"Pediatr Nephrol"},{"key":"3174_CR16","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1053\/ajkd.2002.33382","volume":"39","author":"R Kirpekar","year":"2002","unstructured":"Kirpekar R, Yorgin PD, Tune BM, Kim MK, Sibley RK (2002) Clinicopathologic correlates predict the outcome in children with steroid-resistant idiopathic nephrotic syndrome treated with pulse methylprednisolone therapy. Am J Kidney Dis 39:1143\u20131152","journal-title":"Am J Kidney Dis"},{"key":"3174_CR17","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1007\/s00467-006-0138-y","volume":"21","author":"MM Abrantes","year":"2006","unstructured":"Abrantes MM, Cardoso LS, Lima EM, Penido Silva JM, Diniz JS, Bambirra EA, Oliveira EA (2006) Predictive factors of chronic kidney disease in primary focal segmental glomerulosclerosis. Pediatr Nephrol 21:1003\u20131012","journal-title":"Pediatr Nephrol"},{"key":"3174_CR18","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1007\/s00467-006-0301-5","volume":"22","author":"KH Paik","year":"2007","unstructured":"Paik KH, Lee BH, Cho HY, Kang HG, Ha IS, Cheong HI, Jin DK, Moon KC, Choi Y (2007) Primary focal segmental glomerular sclerosis in children: clinical course and prognosis. Pediatr Nephrol 22:389\u2013395","journal-title":"Pediatr Nephrol"},{"key":"3174_CR19","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1007\/s00467-005-2097-0","volume":"21","author":"DS Gipson","year":"2006","unstructured":"Gipson DS, Chin H, Presler TP, Jennette C, Ferris ME, Massengill S, Gibson K, Thomas DB (2006) Differential risk of remission and ESRD in childhood FSGS. Pediatr Nephrol 21:344\u2013349","journal-title":"Pediatr Nephrol"},{"key":"3174_CR20","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1007\/s004670100639","volume":"16","author":"R Martinelli","year":"2001","unstructured":"Martinelli R, Okumura AS, Pereira LJ, Rocha H (2001) Primary focal segmental glomerulosclerosis in children: prognostic factors. Pediatr Nephrol 16:658\u2013661","journal-title":"Pediatr Nephrol"},{"key":"3174_CR21","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1007\/s00467-008-0860-8","volume":"23","author":"M Mantan","year":"2008","unstructured":"Mantan M, Sriram CS, Hari P, Dinda A, Bagga A (2008) Efficacy of intravenous pulse cyclophosphamide treatment versus combination of intravenous dexamethasone and oral cyclophosphamide treatment in steroid-resistant nephrotic syndrome. Pediatr Nephrol 23:1495\u20131502","journal-title":"Pediatr Nephrol"},{"key":"3174_CR22","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1007\/s004670100680","volume":"16","author":"P Hari","year":"2001","unstructured":"Hari P, Bagga A, Jindal N, Srivastava RN (2001) Treatment of focal glomerulosclerosis with pulse steroids and oral cyclophosphamide. Pediatr Nephrol 16:901\u2013905","journal-title":"Pediatr Nephrol"},{"key":"3174_CR23","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1007\/s00467-003-1095-3","volume":"18","author":"A Bajpai","year":"2003","unstructured":"Bajpai A, Bagga A, Hari P, Dinda A, Srivastava RN (2003) Intravenous cyclophosphamide in steroid-resistant nephrotic syndrome. Pediatr Nephrol 18:351\u2013356","journal-title":"Pediatr Nephrol"},{"key":"3174_CR24","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1007\/s00467-012-2393-4","volume":"28","author":"Y Hamasaki","year":"2013","unstructured":"Hamasaki Y, Yoshikawa N, Nakazato H, Sasaki S, Iijima K, Nakanishi K, Matsuyama T, Ishikura K, Ito S, Kaneko T, Honda M (2013) Prospective 5-year follow-up of cyclosporine treatment in children with steroid-resistant nephrosis. Pediatr Nephrol 28:765\u2013771","journal-title":"Pediatr Nephrol"},{"key":"3174_CR25","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1053\/ajkd.2003.50116","volume":"41","author":"F Fakhouri","year":"2003","unstructured":"Fakhouri F, Bocquet N, Taupin P, Presne C, Gagnadoux MF, Landais P, Lesavre P, Chauveau D, Knebelmann B, Broyer M, Grunfeld JP, Niaudet P (2003) Steroid-sensitive nephrotic syndrome: from childhood to adulthood. Am J Kidney Dis 41:550\u2013557","journal-title":"Am J Kidney Dis"},{"key":"3174_CR26","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.jpeds.2005.03.050","volume":"147","author":"EM Ruth","year":"2005","unstructured":"Ruth EM, Kemper MJ, Leumann EP, Laube GF, Neuhaus TJ (2005) Children with steroid-sensitive nephrotic syndrome come of age: long-term outcome. J Pediatr 147:202\u2013207","journal-title":"J Pediatr"},{"key":"3174_CR27","first-page":"S85","volume":"58","author":"P Niaudet","year":"1997","unstructured":"Niaudet P, Fuchshuber A, Gagnadoux MF, Habib R, Broyer M (1997) Cyclosporine in the therapy of steroid-resistant idiopathic nephrotic syndrome. Kidney Int Suppl 58:S85\u2013S90","journal-title":"Kidney Int Suppl"},{"key":"3174_CR28","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1046\/j.1523-1755.2002.00303.x","volume":"61","author":"K Iijima","year":"2002","unstructured":"Iijima K, Hamahira K, Tanaka R, Kobayashi A, Nozu K, Nakamura H, Yoshikawa N (2002) Risk factor for cyclosporine-induced tubulointerstitial lesions in children with minimal change nephrotic syndrome. Kidney Int 61:1801\u20131805","journal-title":"Kidney Int"},{"key":"3174_CR29","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.2215\/CJN.01520209","volume":"4","author":"S Kengne-Wafo","year":"2009","unstructured":"Kengne-Wafo S, Massella L, Diomedi-Camassei F, Gianviti A, Vivarelli M, Greco M, Stringini GR, Emma F (2009) Risk factors for cyclosporin A nephrotoxicity in children with steroid-dependent nephrotic syndrome. Clin J Am Soc Nephrol 4:1409\u20131416","journal-title":"Clin J Am Soc Nephrol"},{"key":"3174_CR30","doi-asserted-by":"crossref","first-page":"41","DOI":"10.4103\/0971-4065.107197","volume":"23","author":"A Sinha","year":"2013","unstructured":"Sinha A, Sharma A, Mehta A, Gupta R, Gulati A, Hari P, Dinda AK, Bagga A (2013) Calcineurin inhibitor induced nephrotoxicity in steroid resistant nephrotic syndrome. Indian J Nephrol 23:41\u201346","journal-title":"Indian J Nephrol"},{"key":"3174_CR31","doi-asserted-by":"crossref","first-page":"2065","DOI":"10.1007\/s00467-013-2535-3","volume":"28","author":"S Fujinaga","year":"2013","unstructured":"Fujinaga S, Shimizu T (2013) Chronic cyclosporine-induced nephrotoxicity in children with steroid-resistant nephrotic syndrome. Pediatr Nephrol 28:2065\u20132066","journal-title":"Pediatr Nephrol"},{"key":"3174_CR32","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.2215\/CJN.00110112","volume":"7","author":"K Ishikura","year":"2012","unstructured":"Ishikura K, Yoshikawa N, Nakazato H, Sasaki S, Iijima K, Nakanishi K, Matsuyama T, Ito S, Yata N, Ando T, Honda M (2012) Two-year follow-up of a prospective clinical trial of cyclosporine for frequently relapsing nephrotic syndrome in children. Clin J Am Soc Nephrol 7:1576\u20131583","journal-title":"Clin J Am Soc Nephrol"}],"container-title":["Pediatric Nephrology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-015-3174-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00467-015-3174-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-015-3174-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,21]],"date-time":"2022-05-21T06:57:13Z","timestamp":1653116233000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00467-015-3174-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,3]]},"references-count":32,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["3174"],"URL":"https:\/\/doi.org\/10.1007\/s00467-015-3174-7","relation":{},"ISSN":["0931-041X","1432-198X"],"issn-type":[{"value":"0931-041X","type":"print"},{"value":"1432-198X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,3]]}}}