{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T16:23:44Z","timestamp":1764174224797,"version":"3.37.3"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2015,12,21]],"date-time":"2015-12-21T00:00:00Z","timestamp":1450656000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100004963","name":"Seventh Framework Programme (BE)","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004963","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Nephrol"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1007\/s00467-015-3274-4","type":"journal-article","created":{"date-parts":[[2015,12,21]],"date-time":"2015-12-21T13:51:05Z","timestamp":1450705865000},"page":"1001-1010","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Cellular immune profile of kidney transplant patients developing anti-HLA antibodies during childhood"],"prefix":"10.1007","volume":"31","author":[{"given":"Veronica","family":"Santilli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Cagigi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabella","family":"Guzzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Rinaldi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadia","family":"Mora","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federica","family":"Zotta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonina","family":"Piazza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Rossi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Emma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Dello Strologo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Palma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,12,21]]},"reference":[{"key":"3274_CR1","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1056\/NEJMra011295","volume":"346","author":"M Pascual","year":"2002","unstructured":"Pascual M, Theruvath T, Kawai T, Tolkoff-Rubin N, Cosimi AB (2002) Strategies to improve long-term outcomes after renal transplantation. N Engl J Med 346:580\u2013590","journal-title":"N Engl J Med"},{"key":"3274_CR2","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.trim.2011.11.003","volume":"26","author":"O Thaunat","year":"2012","unstructured":"Thaunat O (2012) Humoral immunity in chronic allograft rejection: puzzle pieces come together. Transpl Immunol 26:101\u2013106","journal-title":"Transpl Immunol"},{"key":"3274_CR3","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1111\/j.1432-2277.2005.00085.x","volume":"18","author":"F Cardarelli","year":"2005","unstructured":"Cardarelli F, Delmonico FL, Zhang H, Cosimi AB, Saidman SL (2005) Prevalence and significance of anti-HLA and donor-specific antibodies long-term after renal transplantation. Transpl Int 18:532\u2013540","journal-title":"Transpl Int"},{"key":"3274_CR4","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1034\/j.1600-6143.2003.00135.x","volume":"3","author":"PI Terasaki","year":"2003","unstructured":"Terasaki PI (2003) Humoral theory of transplantation. Am J Transplant 3:665\u2013673","journal-title":"Am J Transplant"},{"key":"3274_CR5","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1097\/TP.0b013e3182a72115","volume":"97","author":"MD Stegall","year":"2014","unstructured":"Stegall MD, Moore N, Taner T, Li H, Dean PG (2014) Down-regulating humoral immune responses: implications for organ transplantation. Transplantation 97:247\u2013257","journal-title":"Transplantation"},{"key":"3274_CR6","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1084\/jem.20072683","volume":"20","author":"S Moir","year":"2008","unstructured":"Moir S, Ho J, Malaspina A, Wang W, DiPoto AC, O'Shea MA, Roby G, Kottilil S, Arthos J, Proschan MA, Chun TW, Fauci AS (2008) Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals. J Exp Med 20:1797\u20131805","journal-title":"J Exp Med"},{"key":"3274_CR7","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/s10522-011-9353-4","volume":"12","author":"S Buffa","year":"2011","unstructured":"Buffa S, Bulati M, Pellican\u00f2 M, Dunn-Walters DK, Wu YC, Candore G, Vitello S, Caruso C, Colonna-Romano G (2011) B cell immunosenescence: different features of naive and memory B cells in elderly. Biogerontology 12:473\u2013483","journal-title":"Biogerontology"},{"key":"3274_CR8","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1182\/blood-2011-12-396648","volume":"120","author":"S Pallikkuth","year":"2012","unstructured":"Pallikkuth S, Parmigiani A, Silva SY, George VK, Fischl M, Pahwa R, Pahwa S (2012) Impaired peripheral blood T-follicular helper cell function in HIV-infected nonresponders to the 2009 H1N1\/09 vaccine. Blood 120:985\u2013993","journal-title":"Blood"},{"key":"3274_CR9","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1111\/j.1365-3083.2011.02591.x","volume":"74","author":"K Bienemann","year":"2011","unstructured":"Bienemann K, Iouannidou K, Schoenberg K, Krux F, Reuther S, Feyen O, Bienemann K, Schuster F, Uhrberg M, Laws HJ, Borkhardt A (2011) iNKT cell frequency in peripheral blood of Caucasian children and adolescent: the absolute iNKT cell count is stable from birth to adulthood. Scand J Immunol 74:406\u2013411","journal-title":"Scand J Immunol"},{"key":"3274_CR10","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1111\/j.1365-2567.2012.03570.x","volume":"136","author":"PJ Berg van de","year":"2012","unstructured":"van de Berg PJ, Hoevenaars EC, Yong SL, van Donselaar-van der Pant KA, van Tellingen A, Florquin S, van Lier RA, Bemelman FJ, ten Berge IJ (2012) Circulating lymphocyte subsets in different clinical situations after renal transplantation. Immunology 136:198\u2013207","journal-title":"Immunology"},{"key":"3274_CR11","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1111\/cei.12173","volume":"174","author":"A Cagigi","year":"2013","unstructured":"Cagigi A, Rinaldi S, Santilli V, Mora N, C Manno E, Cotugno N, Zangari P, Aquilani A, Guzzo I, Dello Strologo L, Rossi P, Palma P (2013) Premature ageing of the immune system relates to increased anti-lymphocyte antibodies (ALA) after an immunization in HIV-1-infected and kidney-transplanted patients. Clin Exp Immunol 174:274\u2013280","journal-title":"Clin Exp Immunol"},{"key":"3274_CR12","doi-asserted-by":"crossref","first-page":"2088","DOI":"10.1111\/j.1600-6143.2012.04053.x","volume":"12","author":"F Porcheray","year":"2012","unstructured":"Porcheray F, DeVito J, Helou Y, Dargon I, Fraser JW, Nobecourt P, Ferdman J, Germana S, Girouard TC, Kawai T, Saidman SL, Wong W, Colvin RB, Leguern C, Zorn E (2012) Expansion of polyreactive B cells cross-reactive to HLA and self in the blood of a patient with kidney graft rejection. Am J Transplant 12:2088\u20132097","journal-title":"Am J Transplant"},{"key":"3274_CR13","doi-asserted-by":"crossref","first-page":"2590","DOI":"10.1111\/ajt.12394","volume":"13","author":"F Porcheray","year":"2013","unstructured":"Porcheray F, Fraser JW, Gao B, McColl A, DeVito J, Dargon I, Helou Y, Wong W, Girouard TC, Saidman SL, Colvin RB, Palmisano A, Maggiore U, Vaglio A, Smith RN, Zorn E (2013) Polyreactive antibodies developing amidst humoral rejection of human kidney grafts bind apoptotic cells and activate complement. Am J Transplant 13:2590\u20132600","journal-title":"Am J Transplant"},{"key":"3274_CR14","doi-asserted-by":"crossref","first-page":"68","DOI":"10.4049\/jimmunol.173.1.68","volume":"173","author":"T Chtanova","year":"2004","unstructured":"Chtanova T, Tangye SG, Newton R, Frank N, Hodge MR, Rolph MS, Mackay CR (2004) T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1\/Th2 effector cells that provide help for B cells. J Immunol 173:68\u201378","journal-title":"J Immunol"},{"key":"3274_CR15","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.4049\/jimmunol.0803009","volume":"182","author":"D Konforte","year":"2009","unstructured":"Konforte D, Simard N, Paige CJ (2009) IL-21: an executor of B cell fate. J Immunol 182:1781\u20131787","journal-title":"J Immunol"},{"key":"3274_CR16","doi-asserted-by":"crossref","first-page":"5236","DOI":"10.4049\/jimmunol.177.8.5236","volume":"177","author":"KL Good","year":"2006","unstructured":"Good KL, Bryant VL, Tangye SG (2006) Kinetics of human B cell behavior and amplification of proliferative responses following stimulation with IL-21. J Immunol 177:5236\u20135247","journal-title":"J Immunol"},{"key":"3274_CR17","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1517\/14728222.2011.561319","volume":"15","author":"M Sarra","year":"2011","unstructured":"Sarra M, Franz\u00e8 E, Pallone F, Monteleone G (2011) Targeting interleukin-21 in inflammatory diseases. Expert Opin Ther Targets 15:695\u2013702","journal-title":"Expert Opin Ther Targets"},{"key":"3274_CR18","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1111\/j.1365-2796.2012.02550.x","volume":"272","author":"N Ruffin","year":"2012","unstructured":"Ruffin N, Lantto R, Pensieroso S, Sammicheli S, Hejdeman B, Rethi B, Chiodi F (2012) Immune activation and increased IL-21R expression are associated with the loss of memory B cells during HIV-1 infection. J Intern Med 272:492\u2013503","journal-title":"J Intern Med"},{"key":"3274_CR19","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1111\/j.1399-0039.2009.01382.x","volume":"74","author":"H S\u00f8ndergaard","year":"2009","unstructured":"S\u00f8ndergaard H, Skak K (2009) IL-21: roles in immunopathology and cancer therapy. Tissue Antigens 74:467\u2013479","journal-title":"Tissue Antigens"},{"key":"3274_CR20","doi-asserted-by":"crossref","first-page":"3638","DOI":"10.3748\/wjg.v16.i29.3638","volume":"16","author":"D Nitto De","year":"2010","unstructured":"De Nitto D, Sarra M, Pallone F, Monteleone G (2010) Interleukin-21 triggers effector cell responses in the gut. World J Gastroenterol 16:3638\u20133641","journal-title":"World J Gastroenterol"},{"key":"3274_CR21","doi-asserted-by":"crossref","first-page":"4077","DOI":"10.1007\/s11033-010-0527-y","volume":"38","author":"J Li","year":"2011","unstructured":"Li J, Pan HF, Cen H, Tian J, Ma Y, Tao JH, Ye DQ (2011) Interleukin-21 as a potential therapeutic target for systemic lupus erythematosus. Mol Biol Rep 38:4077\u20134081","journal-title":"Mol Biol Rep"},{"key":"3274_CR22","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1007\/s11033-010-0285-x","volume":"38","author":"FL Yuan","year":"2011","unstructured":"Yuan FL, Hu W, Lu WG, Li X, Li JP, Xu RS, Li CW, Chen FH, Jin C (2011) Targeting interleukin-21 in rheumatoid arthritis. Mol Biol Rep 38:1717\u20131721","journal-title":"Mol Biol Rep"},{"key":"3274_CR23","doi-asserted-by":"crossref","first-page":"3822","DOI":"10.4049\/jimmunol.178.6.3822","volume":"178","author":"D Herber","year":"2007","unstructured":"Herber D, Brown TP, Liang S, Young DA, Collins M, Dunussi-Joannopoulos K (2007) IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression. J Immunol 178:3822\u20133830","journal-title":"J Immunol"},{"key":"3274_CR24","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1002\/art.22452","volume":"56","author":"DA Young","year":"2007","unstructured":"Young DA, Hegen M, Ma HL, Whitters MJ, Albert LM, Lowe L, Senices M, Wu PW, Sibley B, Leathurby Y, Brown TP, Nickerson-Nutter C, Keith JC Jr, Collins M (2007) Blockade of the interleukin-21\/interleukin-21 receptor pathway ameliorates disease in animal models of rheumatoid arthritis. Arthritis Rheum 56:1152\u20131163","journal-title":"Arthritis Rheum"},{"key":"3274_CR25","doi-asserted-by":"crossref","first-page":"867","DOI":"10.2337\/db10-1157","volume":"60","author":"HM McGuire","year":"2011","unstructured":"McGuire HM, Walters S, Vogelzang A, Lee CM, Webster KE, Sprent J, Christ D, Grey S, King C (2011) Interleukin-21 is critically required in autoimmune and allogeneic responses to islet tissue in murine models. Diabetes 60:867\u2013875","journal-title":"Diabetes"},{"key":"3274_CR26","doi-asserted-by":"crossref","first-page":"3223","DOI":"10.2337\/db11-0880","volume":"60","author":"A Petrelli","year":"2011","unstructured":"Petrelli A, Carvello M, Vergani A, Lee KM, Tezza S, Du M, Kleffel S, Chengwen L, Mfarrej BG, Hwu P, Secchi A, Leonard WJ, Young D, Sayegh MH, Markmann JF, Zajac AJ, Fiorina P (2011) IL-21 is an antitolerogenic cytokine of the late-phase alloimmune response. Diabetes 60:3223\u20133234","journal-title":"Diabetes"},{"key":"3274_CR27","doi-asserted-by":"crossref","first-page":"1836","DOI":"10.1172\/JCI39933","volume":"120","author":"KA Newell","year":"2010","unstructured":"Newell KA, Asare A, Kirk AD, Gisler TD, Bourcier K, Suthanthiran M, Burlingham WJ, Marks WH, Sanz I, Lechler RI, Hernandez-Fuentes MP, Turka LA, Seyfert-Margolis VL (2010) Immune tolerance network ST507 study group. Identification of a B cell signature associated with renal transplant tolerance in humans. J Clin Invest 120:1836\u20131847","journal-title":"J Clin Invest"},{"key":"3274_CR28","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1172\/JCI39922","volume":"120","author":"P Sagoo","year":"2000","unstructured":"Sagoo P, Perucha E, Sawitzki B, Tomiuk S, Stephens DA, Miqueu P, Chapman S, Craciun L, Sergeant R, Brouard S, Rovis F, Jimenez E, Ballow A, Giral M, Rebollo-Mesa I, Le Moine A, Braudeau C, Hilton R, Gerstmayer B, Bourcier K, Sharif A, Krajewska M, Lord GM, Roberts I, Goldman M, Wood KJ, Newell K, Seyfert-Margolis V, Warrens AN, Janssen U, Volk HD, Soulillou JP, Hernandez-Fuentes MP, Lechler RI (2000) Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans. J Clin Invest 120:1848\u20131861","journal-title":"J Clin Invest"},{"key":"3274_CR29","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1084\/jem.20120994","volume":"209","author":"CS Ma","year":"2012","unstructured":"Ma CS, Deenick EK, Batten M, Tangye SG (2012) The origins, function, and regulation of T follicular helper cells. J Exp Med 209:1241\u20131253","journal-title":"J Exp Med"},{"key":"3274_CR30","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1111\/cei.12576","volume":"180","author":"GN Graav de","year":"2014","unstructured":"de Graav GN, Dieterich M, Hesselink DA, Boer K, Clahsen-van Groningen MC, Kraaijeveld R, Litjens NH, Bouamar R, Vanderlocht J, Tilanus M, Houba I, Boonstra A, Roelen DL, Claas FH, Betjes MG, Weimar W, Baan CC (2014) Follicular T-helper cells and humoral reactivity in kidney-transplant patients. Clin Exp Immunol 180:329\u2013340","journal-title":"Clin Exp Immunol"},{"key":"3274_CR31","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1111\/tri.12160","volume":"27","author":"MR Clatworthy","year":"2014","unstructured":"Clatworthy MR (2014) B-cell regulation and its application to transplantation. Transpl Int 27:117\u2013128","journal-title":"Transpl Int"},{"key":"3274_CR32","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/ajt.12526","volume":"14","author":"EJ Kim","year":"2014","unstructured":"Kim EJ, Kwun J, Gibby AC, Hong JJ, Farris AB 3rd, Iwakoshi NN, Villinger F, Kirk AD, Knechtle SJ (2014) Costimulation blockade alters germinal center responses and prevents antibody-mediated rejection. Am J Transplant 14:59\u201369","journal-title":"Am J Transplant"},{"key":"3274_CR33","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.1111\/j.1600-6143.2009.02742.x","volume":"9","author":"C Macedo","year":"2009","unstructured":"Macedo C, Orkis EA, Popescu I, Elinoff BD, Zeevi A, Shapiro R, Lakkis FG, Metes D (2009) Contribution of na\u00efve and memory T-cell populations to the human alloimmune response. Am J Transplant 9:2057\u20132066","journal-title":"Am J Transplant"},{"key":"3274_CR34","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/j.1600-6143.2011.03762.x","volume":"12","author":"WH Kitchens","year":"2012","unstructured":"Kitchens WH, Haridas D, Wagener ME, Song M, Kirk AD, Larsen CP, Ford ML (2012) Integrin antagonists prevent costimulatory blockade-resistant transplant rejection by CD8(+) memory T cells. Am J Transplant 12:69\u201380","journal-title":"Am J Transplant"},{"key":"3274_CR35","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1111\/j.1600-6143.2011.03492.x","volume":"11","author":"K Setoguchi","year":"2011","unstructured":"Setoguchi K, Schenk AD, Ishii D, Hattori Y, Baldwin WM 3rd, Tanabe K, Fairchild RL (2011) LFA-1 antagonism inhibits early infiltration of endogenous memory CD8 T cells into cardiac allografts and donor-reactive T cell priming. Am J Transplant 11:923\u2013935","journal-title":"Am J Transplant"},{"key":"3274_CR36","doi-asserted-by":"crossref","first-page":"5030","DOI":"10.1182\/blood-2011-11-389304","volume":"119","author":"A Chaidos","year":"2012","unstructured":"Chaidos A, Patterson S, Szydlo R, Chaudhry MS, Dazzi F, Kanfer E, McDonald D, Marin D, Milojkovic D, Pavlu J, Davis J, Rahemtulla A, Rezvani K, Goldman J, Roberts I, Apperley J, Karadimitris A (2012) Graft invariant natural killer T-cell dose predicts risk of acute graft-versus-host disease in allogeneic hematopoietic stem cell transplantation. Blood 119:5030\u20135036","journal-title":"Blood"},{"key":"3274_CR37","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1182\/blood-2005-02-0509","volume":"106","author":"A Beilhack","year":"2005","unstructured":"Beilhack A, Schulz S, Baker J, Beilhack GF, Wieland CB, Herman EI, Baker EM, Cao YA, Contag CH, Negrin RS (2005) In vivo analyses of early events in acute graft-versus-host disease reveal sequential infiltration of T-cell subsets. Blood 106:1113\u20131122","journal-title":"Blood"},{"key":"3274_CR38","doi-asserted-by":"crossref","first-page":"3116","DOI":"10.1182\/blood-2013-08-453126","volume":"122","author":"D Schneidawind","year":"2013","unstructured":"Schneidawind D, Pierini A, Negrin RS (2013) Regulatory T cells and natural killer T cells for modulation of GVHD following allogeneic hematopoietic cell transplantation. Blood 122:3116\u20133121","journal-title":"Blood"},{"key":"3274_CR39","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1172\/JCI8922","volume":"105","author":"Y Ikehara","year":"2000","unstructured":"Ikehara Y, Yasunami Y, Kodama S, Maki T, Nakano M, Nakayama T, Taniguchi M, Ikeda S (2000) CD4(+) Valpha14 natural killer T cells are essential for acceptance of rat islet xenografts in mice. J Clin Invest 105:1761\u20131767","journal-title":"J Clin Invest"},{"key":"3274_CR40","doi-asserted-by":"crossref","first-page":"2577","DOI":"10.1073\/pnas.041608298","volume":"98","author":"KI Seino","year":"2001","unstructured":"Seino KI, Fukao K, Muramoto K, Yanagisawa K, Takada Y, Kakuta S, Iwakura Y, Van Kaer L, Takeda K, Nakayama T, Taniguchi M, Bashuda H, Yagita H, Okumura K (2001) Requirement for natural killer T (NKT) cells in the induction of allograft tolerance. Proc Natl Acad Sci U S A 98:2577\u20132581","journal-title":"Proc Natl Acad Sci U S A"},{"key":"3274_CR41","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1111\/j.1600-6143.2007.01827.x","volume":"7","author":"X Jiang","year":"2007","unstructured":"Jiang X, Kojo S, Harada M, Ohkohchi N, Taniguchi M, Seino KI (2007) Mechanism of NKT cell-mediated transplant tolerance. Am J Transplant 7:1482\u20131490","journal-title":"Am J Transplant"},{"key":"3274_CR42","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1111\/j.1432-2277.2009.00884.x","volume":"22","author":"J Pratschke","year":"2009","unstructured":"Pratschke J, Stauch D, Kotsch K (2009) Role of NK and NKT cells in solid organ transplantation. Transpl Int 22:859\u2013868","journal-title":"Transpl Int"},{"key":"3274_CR43","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.trre.2015.02.001","volume":"29","author":"M Crespo","year":"2015","unstructured":"Crespo M, Heidt S, Redondo D, Pascual J (2015) Monitoring B cell subsets and alloreactivity in kidney transplantation. Transplant Rev (Orlando) 29:45\u201352","journal-title":"Transplant Rev (Orlando)"},{"key":"3274_CR44","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1111\/ajt.13122","volume":"15","author":"S Shabir","year":"2015","unstructured":"Shabir S, Girdlestone J, Briggs D, Kaul B, Smith H, Daga S, Chand S, Jham S, Navarrete C, Harper L, Ball S, Borrows R (2015) Transitional B lymphocytes are associated with protection from kidney allograft rejection: a prospective study. Am J Transplant 15:1384\u20131391","journal-title":"Am J Transplant"}],"container-title":["Pediatric Nephrology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-015-3274-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00467-015-3274-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-015-3274-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,30]],"date-time":"2022-05-30T01:15:35Z","timestamp":1653873335000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00467-015-3274-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,21]]},"references-count":44,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,6]]}},"alternative-id":["3274"],"URL":"https:\/\/doi.org\/10.1007\/s00467-015-3274-4","relation":{},"ISSN":["0931-041X","1432-198X"],"issn-type":[{"type":"print","value":"0931-041X"},{"type":"electronic","value":"1432-198X"}],"subject":[],"published":{"date-parts":[[2015,12,21]]}}}