{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T13:58:21Z","timestamp":1780408701205,"version":"3.54.1"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2016,1,12]],"date-time":"2016-01-12T00:00:00Z","timestamp":1452556800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Nephrol"],"published-print":{"date-parts":[[2016,4]]},"DOI":"10.1007\/s00467-015-3285-1","type":"journal-article","created":{"date-parts":[[2016,1,12]],"date-time":"2016-01-12T15:58:40Z","timestamp":1452614320000},"page":"595-604","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Body weight-based prednisolone versus body surface area-based prednisolone regimen for induction of remission in children with nephrotic syndrome: a randomized, open-label, equivalence clinical trial"],"prefix":"10.1007","volume":"31","author":[{"given":"Vaishnavi","family":"Raman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sriram","family":"Krishnamurthy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. T.","family":"Harichandrakumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,1,12]]},"reference":[{"key":"3285_CR1","doi-asserted-by":"crossref","unstructured":"Barnett HL (1979) Nephrotic syndrome in children: a randomized trial comparing two prednisone regimens in steroid-responsive patients who relapse early. Report of the international study of kidney disease in children. J Pediatr 95:228\u2013233","DOI":"10.1016\/S0022-3476(79)80658-7"},{"key":"3285_CR2","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1681\/ASN.2005090922","volume":"17","author":"PF Hoyer","year":"2006","unstructured":"Hoyer PF, Brodehl J (2006) Initial treatment of idiopathic nephrotic syndrome in children: prednisone versus prednisone plus cyclosporine a: a prospective, randomized trial. J Am Soc Nephrol 17:1151\u20131157","journal-title":"J Am Soc Nephrol"},{"key":"3285_CR3","unstructured":"Brodehl J, Ehrich JH (1988) Short versus standard prednisone therapy for initial treatment of idiopathic nephrotic syndrome in children. Arbeitsgemeinschaft f\u00fcr P\u00e4diatrische Nephrologie. Lancet 1:380\u2013383"},{"key":"3285_CR4","doi-asserted-by":"crossref","first-page":"30","DOI":"10.2165\/00003495-199142010-00003","volume":"42","author":"T Melvin","year":"1991","unstructured":"Melvin T, Bennett W (1991) Management of nephrotic syndrome in childhood. Drugs 42:30\u201351","journal-title":"Drugs"},{"key":"3285_CR5","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/BF01956754","volume":"152","author":"JH Ehrich","year":"1993","unstructured":"Ehrich JH, Brodehl J (1993) Long versus standard prednisone therapy for initial treatment of idiopathic nephrotic syndrome in children. Arbeitsgemeinschaft f\u00fcr P\u00e4diatrische Nephrologie. Eur J Pediatr 152:357\u2013361","journal-title":"Eur J Pediatr"},{"key":"3285_CR6","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1358\/dot.1999.35.1.522942","volume":"35","author":"B Gauthier","year":"1999","unstructured":"Gauthier B, Trachtman H (1999) Pharmacological treatment of nephrotic syndrome. Drugs Today (Barc) 35:13\u201326","journal-title":"Drugs Today (Barc)"},{"issue":"Suppl 6","key":"3285_CR7","first-page":"vi75","volume":"18","author":"G Filler","year":"2003","unstructured":"Filler G (2003) Treatment of nephrotic syndrome in children and controlled trials. Nephrol Dial Transplant 18 [Suppl 6]:vi75\u2013vi78","journal-title":"Nephrol Dial Transplant"},{"key":"3285_CR8","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/S0272-6386(03)00346-9","volume":"41","author":"M Hiraoka","year":"2003","unstructured":"Hiraoka M, Tsukahara H, Matsubara K, Tsurusawa M, Takeda N, Haruki S, Hayashi S, Ohta K, Momoi T, Ohshima Y, Suganuma N, Mayumi M, West Japan Cooperative Study Group of Kidney Disease in Children (2003) A randomized study of two long course prednisolone regimens for nephrotic syndrome in children. Am J Kidney Dis 41:1155\u20131162","journal-title":"Am J Kidney Dis"},{"key":"3285_CR9","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1111\/j.1651-2227.1995.tb13787.x","volume":"84","author":"J Ksiazek","year":"1995","unstructured":"Ksiazek J, Wyszy\u0144ska T (1995) Short versus long initial prednisone treatment in steroid-sensitive nephrotic syndrome in children. Acta Paediatr 84:889\u2013893","journal-title":"Acta Paediatr"},{"key":"3285_CR10","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1007\/s004670050708","volume":"13","author":"A Bagga","year":"1999","unstructured":"Bagga A, Hari P, Srivastava RN (1999) Prolonged versus standard prednisolone therapy for initial episode of nephrotic syndrome. Pediatr Nephrol 13:824\u2013827","journal-title":"Pediatr Nephrol"},{"key":"3285_CR11","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1007\/s004670050344","volume":"11","author":"BK Ekka","year":"1997","unstructured":"Ekka BK, Bagga A, Srivastava RN (1997) Single-versus divided-dose prednisolone therapy for relapses of nephrotic syndrome. Pediatr Nephrol 11:597\u2013599","journal-title":"Pediatr Nephrol"},{"key":"3285_CR12","first-page":"203","volume":"45","author":"A Bagga","year":"2008","unstructured":"Indian Pediatric Nephrology Group, Indian Academy of Pediatrics, Bagga A, Ali U, Banerjee S, Kanitkar M, Phadke KD, Senguttuvan P, Sethi S, Shah M (2008) Management of steroid sensitive nephrotic syndrome: revised guidelines. Indian Pediatr 45:203\u2013214","journal-title":"Indian Pediatr"},{"key":"3285_CR13","volume":"4","author":"EM Hodson","year":"2007","unstructured":"Hodson EM, Willis NS, Craig JC (2007) Corticosteroid therapy for nephrotic syndrome in children. Cochrane Database Syst Rev 4, CD001533","journal-title":"Cochrane Database Syst Rev"},{"key":"3285_CR14","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1007\/s00467-008-1089-2","volume":"24","author":"J Feber","year":"2009","unstructured":"Feber J, Al-Matrafi J, Farhadi E, Vaillancourt R, Wolfish N (2009) Prednisone dosing per body weight or body surface area in children with nephrotic syndrome\u2014is it equivalent? Pediatr Nephrol 24:1027\u20131031","journal-title":"Pediatr Nephrol"},{"key":"3285_CR15","doi-asserted-by":"crossref","first-page":"2167","DOI":"10.1007\/s00467-011-1961-3","volume":"26","author":"SA Saadeh","year":"2011","unstructured":"Saadeh SA, Baracco R, Jain A, Kapur G, Mattoo TK, Valentini RP (2011) Weight or body surface area dosing of steroids in nephrotic syndrome: is there an outcome difference? Pediatr Nephrol 26:2167\u20132171","journal-title":"Pediatr Nephrol"},{"key":"3285_CR16","doi-asserted-by":"crossref","first-page":"2095","DOI":"10.1007\/s00467-011-1993-8","volume":"26","author":"O Mehls","year":"2011","unstructured":"Mehls O, Hoyer PF (2011) Dosing of glucocorticosteroids in nephrotic syndrome. Pediatr Nephrol 26:2095\u20132098","journal-title":"Pediatr Nephrol"},{"key":"3285_CR17","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1542\/peds.114.2.S2.555","volume":"114","author":"National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents","year":"2004","unstructured":"National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents (2004) The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics 114:555\u2013576","journal-title":"Pediatrics"},{"key":"3285_CR18","doi-asserted-by":"crossref","first-page":"e907","DOI":"10.1542\/peds.2006-2164","volume":"119","author":"BG Hinkes","year":"2007","unstructured":"Hinkes BG, Mucha B, Vlangos CN, Gbadegesin R, Liu J, Hasselbacher K, Hangan D, Ozaltin F, Zenker M, Hildebrandt F, Arbeitsgemeinschaft f\u00fcr Paediatrische Nephrologie Study Group (2007) Nephrotic syndrome in the first year of life: two thirds of cases are caused by mutations in 4 genes (NPHS1, NPHS2, WT1, and LAMB2). Pediatrics 119:e907\u2013e919","journal-title":"Pediatrics"},{"key":"3285_CR19","first-page":"1098","volume":"317","author":"RD Mosteller","year":"1987","unstructured":"Mosteller RD (1987) Simplified calculation of body-surface area. N Engl J Med 317:1098","journal-title":"N Engl J Med"},{"key":"3285_CR20","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1007\/s00467-011-2091-7","volume":"27","author":"TJ Neuhaus","year":"2012","unstructured":"Neuhaus TJ, Laube GF (2012) Weight dosing of steroids in nephrotic syndrome. Pediatr Nephrol 27:505","journal-title":"Pediatr Nephrol"},{"key":"3285_CR21","volume":"3","author":"D Hahn","year":"2015","unstructured":"Hahn D, Hodson EM, Willis NS, Craig JC (2015) Corticosteroid therapy for nephrotic syndrome in children. Cochrane Database Syst Rev 3:CD001533","journal-title":"Cochrane Database Syst Rev"},{"key":"3285_CR22","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1038\/ki.2014.240","volume":"87","author":"A Sinha","year":"2015","unstructured":"Sinha A, Saha A, Kumar M, Sharma S, Afzal K, Mehta A, Kalaivani M, Hari P, Bagga A (2015) Extending initial prednisolone treatment in a randomized control trial from 3 to 6\u00a0months did not significantly influence the course of illness in children with steroid-sensitive nephrotic syndrome. Kidney Int 87:217\u2013224","journal-title":"Kidney Int"},{"key":"3285_CR23","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1038\/ki.2014.260","volume":"87","author":"N Yoshikawa","year":"2015","unstructured":"Yoshikawa N, Nakanishi K, Sako M, Oba MS, Mori R, Ota E, Ishikura K, Hataya H, Honda M, Ito S, Shima Y, Kaito H, Nozu K, Nakamura H, Igarashi T, Ohashi Y, Iijima K, Japanese Study Group of Kidney Disease in Children (2015) A multicenter randomized trial indicates initial prednisolone treatment for childhood nephrotic syndrome for two months is not inferior to six-month treatment. Kidney Int 87:225\u2013232","journal-title":"Kidney Int"},{"key":"3285_CR24","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1038\/ki.2014.354","volume":"87","author":"PF Hoyer","year":"2015","unstructured":"Hoyer PF (2015) New lessons from randomized trials in steroid-sensitive nephrotic syndrome: clear evidence against long steroid therapy. Kidney Int 87:17\u201319","journal-title":"Kidney Int"},{"key":"3285_CR25","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1053\/ajkd.2003.50116","volume":"41","author":"F Fakhouri","year":"2003","unstructured":"Fakhouri F, Bocquet N, Taupin P, Presne C, Gagnadoux MF, Landais P, Lesavre P, Chauveau D, Knebelmann B, Broyer M, Gr\u00fcnfeld JP, Niaudet P (2003) Steroid-sensitive nephrotic syndrome: from childhood to adulthood. Am J Kidney Dis 41:550\u2013557","journal-title":"Am J Kidney Dis"},{"key":"3285_CR26","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1056\/NEJMoa040367","volume":"351","author":"MB Leonard","year":"2004","unstructured":"Leonard MB, Feldman HI, Shults J, Zemel BS, Foster BJ, Stallings VA (2004) Long-term, high-dose glucocorticoids and bone mineral content in childhood glucocorticoid-sensitive nephrotic syndrome. N Engl J Med 351:868\u2013875","journal-title":"N Engl J Med"},{"key":"3285_CR27","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.jpeds.2005.03.050","volume":"147","author":"EM R\u00fcth","year":"2005","unstructured":"R\u00fcth EM, Kemper MJ, Leumann EP, Laube GF, Neuhaus TJ (2005) Children with steroid-sensitive nephrotic syndrome come of age: long-term outcome. J Pediatr 147:202\u2013207","journal-title":"J Pediatr"},{"key":"3285_CR28","doi-asserted-by":"crossref","first-page":"1593","DOI":"10.2215\/CJN.05691108","volume":"4","author":"HA Kyrieleis","year":"2009","unstructured":"Kyrieleis HA, L\u00f6wik MM, Pronk I, Cruysberg HR, Kremer JA, Oyen WJ, van den Heuvel BL, Wetzels JF, Levtchenko EN (2009) Long-term outcome of biopsy-proven, frequently relapsing minimal-change nephrotic syndrome in children. Clin J Am Soc Nephrol 4:1593\u20131600","journal-title":"Clin J Am Soc Nephrol"}],"container-title":["Pediatric Nephrology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-015-3285-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00467-015-3285-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-015-3285-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T01:07:14Z","timestamp":1559092034000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00467-015-3285-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1,12]]},"references-count":28,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,4]]}},"alternative-id":["3285"],"URL":"https:\/\/doi.org\/10.1007\/s00467-015-3285-1","relation":{},"ISSN":["0931-041X","1432-198X"],"issn-type":[{"value":"0931-041X","type":"print"},{"value":"1432-198X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,1,12]]}}}