{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T05:15:48Z","timestamp":1793164548688,"version":"4.5.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2019,11,8]],"date-time":"2019-11-08T00:00:00Z","timestamp":1573171200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,11,8]],"date-time":"2019-11-08T00:00:00Z","timestamp":1573171200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Nephrol"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1007\/s00467-019-04398-1","type":"journal-article","created":{"date-parts":[[2019,11,8]],"date-time":"2019-11-08T16:01:16Z","timestamp":1573228876000},"page":"455-462","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":60,"title":["Immunoglobulin serum levels in rituximab-treated patients with steroid-dependent nephrotic syndrome"],"prefix":"10.1007","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3849-2659","authenticated-orcid":false,"given":"Cyrielle","family":"Parmentier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Daniel","family":"Delbet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Decramer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia","family":"Boyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julien","family":"Hogan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Ulinski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,11,8]]},"reference":[{"key":"4398_CR1","first-page":"1083","volume":"27","author":"A-L Sellier-Leclerc","year":"2012","unstructured":"Sellier-Leclerc A-L, Baudouin V, Kwon T, Macher M-A, Gu\u00e9rin V, Lapillonne H, Desch\u00eanes G, Ulinski T (2012) Rituximab in steroid-dependent idiopathic nephrotic syndrome in childhood--follow-up after CD19 recovery. Nephrol Dial Transplant Off Publ Eur Dial Transpl Assoc - Eur Ren Assoc 27:1083\u20131089","journal-title":"Nephrol Dial Transplant Off Publ Eur Dial Transpl Assoc - Eur Ren Assoc"},{"key":"4398_CR2","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1007\/s00467-009-1377-5","volume":"25","author":"S Fujinaga","year":"2010","unstructured":"Fujinaga S, Hirano D, Nishizaki N, Kamei K, Ito S, Ohtomo Y, Shimizu T, Kaneko K (2010) Single infusion of rituximab for persistent steroid-dependent minimal-change nephrotic syndrome after long-term cyclosporine. Pediatr Nephrol Berl Ger 25:539\u2013544","journal-title":"Pediatr Nephrol Berl Ger"},{"key":"4398_CR3","doi-asserted-by":"publisher","first-page":"1811","DOI":"10.1681\/ASN.2015050523","volume":"27","author":"M Colucci","year":"2016","unstructured":"Colucci M, Carsetti R, Cascioli S, Casiraghi F, Perna A, Rav\u00e0 L, Ruggiero B, Emma F, Vivarelli M (2016) B Cell Reconstitution after Rituximab Treatment in Idiopathic Nephrotic Syndrome. J Am Soc Nephrol JASN 27:1811\u20131822","journal-title":"J Am Soc Nephrol JASN"},{"key":"4398_CR4","doi-asserted-by":"publisher","first-page":"1269","DOI":"10.1007\/s00467-008-0814-1","volume":"23","author":"V Guigonis","year":"2008","unstructured":"Guigonis V, Dallocchio A, Baudouin V, Dehennault M, Hachon-Le Camus C, Afanetti M, Groothoff J, Llanas B, Niaudet P, Nivet H, Raynaud N, Taque S, Ronco P, Bouissou F (2008) Rituximab treatment for severe steroid- or cyclosporine-dependent nephrotic syndrome: a multicentric series of 22 cases. Pediatr Nephrol Berl Ger 23:1269\u20131279","journal-title":"Pediatr Nephrol Berl Ger"},{"key":"4398_CR5","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.1007\/s00467-010-1465-6","volume":"25","author":"A-L Sellier-Leclerc","year":"2010","unstructured":"Sellier-Leclerc A-L, Macher M-A, Loirat C, Gu\u00e9rin V, Watier H, Peuchmaur M, Baudouin V, Desch\u00eanes G (2010) Rituximab efficiency in children with steroid-dependent nephrotic syndrome. Pediatr Nephrol Berl Ger 25:1109\u20131115","journal-title":"Pediatr Nephrol Berl Ger"},{"key":"4398_CR6","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1159\/000356439","volume":"38","author":"T Kimata","year":"2013","unstructured":"Kimata T, Hasui M, Kino J, Kitao T, Yamanouchi S, Tsuji S, Kaneko K (2013) Novel use of rituximab for steroid-dependent nephrotic syndrome in children. Am J Nephrol 38:483\u2013488","journal-title":"Am J Nephrol"},{"key":"4398_CR7","doi-asserted-by":"publisher","first-page":"P42","DOI":"10.1186\/2045-7022-4-S1-P42","volume":"4","author":"JE Trujillo","year":"2014","unstructured":"Trujillo JE, Bosque M, Asensio \u00d2, Ranera A, Rojo JC, Vilella M, Guijarro E, Domingo X, Valdesoiro L, Larramona H (2014) PD42 - Is rituximab a trigger for persistent hypogammaglobulinemia in idiopathic nephrotic syndrome? Clin Transl Allergy 4:P42","journal-title":"Clin Transl Allergy"},{"key":"4398_CR8","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2018.4169","volume":"1","author":"S Barmettler","year":"2018","unstructured":"Barmettler S, Ong M-S, Farmer JR, Choi H, Walter J (2018) Association of Immunoglobulin Levels, Infectious Risk, and Mortality With Rituximab and Hypogammaglobulinemia. JAMA Netw Open 1:e184169","journal-title":"JAMA Netw Open"},{"key":"4398_CR9","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.jaut.2014.11.009","volume":"57","author":"DM Roberts","year":"2015","unstructured":"Roberts DM, Jones RB, Smith RM, Alberici F, Kumaratne DS, Burns S, Jayne DRW (2015) Rituximab-associated hypogammaglobulinemia: incidence, predictors and outcomes in patients with multi-system autoimmune disease. J Autoimmun 57:60\u201365","journal-title":"J Autoimmun"},{"key":"4398_CR10","doi-asserted-by":"publisher","first-page":"1818","DOI":"10.1093\/rheumatology\/keu194","volume":"53","author":"E Besada","year":"2014","unstructured":"Besada E, Koldingsnes W, Nossent JC (2014) Serum immunoglobulin levels and risk factors for hypogammaglobulinaemia during long-term maintenance therapy with rituximab in patients with granulomatosis with polyangiitis. Rheumatol Oxf Engl 53:1818\u20131824","journal-title":"Rheumatol Oxf Engl"},{"key":"4398_CR11","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1007\/s00467-012-2361-z","volume":"28","author":"L Delbe-Bertin","year":"2013","unstructured":"Delbe-Bertin L, Aoun B, Tudorache E, Lapillone H, Ulinski T (2013) Does rituximab induce hypogammaglobulinemia in patients with pediatric idiopathic nephrotic syndrome? Pediatr Nephrol Berl Ger 28:447\u2013451","journal-title":"Pediatr Nephrol Berl Ger"},{"key":"4398_CR12","doi-asserted-by":"publisher","first-page":"340","DOI":"10.5414\/CN108835","volume":"85","author":"S Fujinaga","year":"2016","unstructured":"Fujinaga S, Ozawa K, Sakuraya K, Yamada A, Shimizu T (2016) Late-onset adverse events after a single dose of rituximab in children with complicated steroid-dependent nephrotic syndrome. Clin Nephrol 85:340\u2013345","journal-title":"Clin Nephrol"},{"key":"4398_CR13","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1093\/clinchem\/28.1.126","volume":"28","author":"CR Jolliff","year":"1982","unstructured":"Jolliff CR, Cost KM, Stivrins PC, Grossman PP, Nolte CR, Franco SM, Fijan KJ, Fletcher LL, Shriner HC (1982) Reference intervals for serum IgG, IgA, IgM, C3, and C4 as determined by rate nephelometry. Clin Chem 28:126\u2013128","journal-title":"Clin Chem"},{"key":"4398_CR14","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1016\/S1081-1206(10)60665-5","volume":"99","author":"S Agarwal","year":"2007","unstructured":"Agarwal S, Cunningham-Rundles C (2007) Assessment and clinical interpretation of reduced IgG values. Ann Allergy Asthma Immunol Off Publ Am Coll Allergy Asthma Immunol 99:281\u2013283","journal-title":"Ann Allergy Asthma Immunol Off Publ Am Coll Allergy Asthma Immunol"},{"key":"4398_CR15","doi-asserted-by":"publisher","first-page":"1875","DOI":"10.1007\/s00467-013-2485-9","volume":"28","author":"A-L Sellier-Leclerc","year":"2013","unstructured":"Sellier-Leclerc A-L, Belli E, Gu\u00e9rin V, Dorfm\u00fcller P, Desch\u00eanes G (2013) Fulminant viral myocarditis after rituximab therapy in pediatric nephrotic syndrome. Pediatr Nephrol Berl Ger 28:1875\u20131879","journal-title":"Pediatr Nephrol Berl Ger"},{"key":"4398_CR16","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1007\/s00467-018-4145-6","volume":"34","author":"S Fujinaga","year":"2019","unstructured":"Fujinaga S, Nishino T, Umeda C, Tomii Y, Watanabe Y, Sakuraya K (2019) Long-term outcomes after early treatment with rituximab for Japanese children with cyclosporine- and steroid-resistant nephrotic syndrome. Pediatr Nephrol Berl Ger 34:353\u2013357","journal-title":"Pediatr Nephrol Berl Ger"},{"key":"4398_CR17","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1080\/08830185.2017.1346092","volume":"36","author":"EAA Christou","year":"2017","unstructured":"Christou EAA, Giardino G, Worth A, Ladomenou F (2017) Risk factors predisposing to the development of hypogammaglobulinemia and infections post-Rituximab. Int Rev Immunol 36:352\u2013359","journal-title":"Int Rev Immunol"},{"key":"4398_CR18","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1093\/rheumatology\/keq368","volume":"50","author":"X Mariette","year":"2011","unstructured":"Mariette X, Gottenberg J-E, Ravaud P, Combe B (2011) Registries in rheumatoid arthritis and autoimmune diseases: data from the French registries. Rheumatol Oxf Engl 50:222\u2013229","journal-title":"Rheumatol Oxf Engl"},{"key":"4398_CR19","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1007\/s00467-018-4052-x","volume":"34","author":"J Hogan","year":"2019","unstructured":"Hogan J, Dossier C, Kwon T, Macher M-A, Maisin A, Couderc A, Niel O, Baudouin V, Desch\u00eanes G (2019) Effect of different rituximab regimens on B cell depletion and time to relapse in children with steroid-dependent nephrotic syndrome. Pediatr Nephrol Berl Ger 34:253\u2013259","journal-title":"Pediatr Nephrol Berl Ger"},{"key":"4398_CR20","doi-asserted-by":"publisher","first-page":"1252","DOI":"10.1016\/j.jpeds.2012.11.038","volume":"162","author":"M Kavcic","year":"2013","unstructured":"Kavcic M, Fisher BT, Seif AE, Li Y, Huang Y-S, Walker D, Aplenc R (2013) Leveraging administrative data to monitor rituximab use in 2875 patients at 42 freestanding children\u2019s hospitals across the United States. J Pediatr 162:1252\u20131258 1258.e1","journal-title":"J Pediatr"},{"key":"4398_CR21","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1542\/peds.113.4.701","volume":"113","author":"IC Michelow","year":"2004","unstructured":"Michelow IC, Olsen K, Lozano J, Rollins NK, Duffy LB, Ziegler T, Kauppila J, Leinonen M, McCracken GH (2004) Epidemiology and clinical characteristics of community-acquired pneumonia in hospitalized children. Pediatrics 113:701\u2013707","journal-title":"Pediatrics"},{"key":"4398_CR22","doi-asserted-by":"publisher","first-page":"1407","DOI":"10.1016\/j.jaci.2015.06.035","volume":"136","author":"S Barmettler","year":"2015","unstructured":"Barmettler S, Price C (2015) Continuing IgG replacement therapy for hypogammaglobulinemia after rituximab--for how long? J Allergy Clin Immunol 136:1407\u20131409","journal-title":"J Allergy Clin Immunol"}],"container-title":["Pediatric Nephrology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-019-04398-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00467-019-04398-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-019-04398-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,7]],"date-time":"2021-01-07T18:54:22Z","timestamp":1610045662000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00467-019-04398-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,8]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["4398"],"URL":"https:\/\/doi.org\/10.1007\/s00467-019-04398-1","relation":{},"ISSN":["0931-041X","1432-198X"],"issn-type":[{"value":"0931-041X","type":"print"},{"value":"1432-198X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,8]]},"assertion":[{"value":"27 June 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 September 2019","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 October 2019","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 November 2019","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}