{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T15:42:05Z","timestamp":1772811725542,"version":"3.50.1"},"reference-count":66,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2020,1,2]],"date-time":"2020-01-02T00:00:00Z","timestamp":1577923200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,1,2]],"date-time":"2020-01-02T00:00:00Z","timestamp":1577923200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100000764","name":"King's College London","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000764","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Nephrol"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Living donor kidney transplantation is the optimal treatment for end-stage kidney disease (ESKD) but confers a risk upon the donor, both in the short term and many years after donation. While perioperative mortality is low and longevity does not appear to be adversely affected, there are small increases in the risk of other important morbidities. The overall risk of ESKD among donors is low but appears to be three- to five-fold higher than among healthy non-donors, and this relative risk is even higher among donors of African ancestry. For these individuals, apolipoprotein L1 genotyping may be helpful. Kidney donors also have an increased risk of developing hypertension post-donation and a modestly increased risk of developing gout. Living kidney donation also increases the risk of gestational hypertension and preeclampsia while not affecting other important pregnancy outcomes. As our understanding of donor risk grows, it is important to counsel prospective donors according to their individual risk and so obtain better informed donor consent. As knowledge advances, it is also important that all clinicians who manage kidney transplant candidates have an up to date understanding of donor risk to inform shared decision making.<\/jats:p>","DOI":"10.1007\/s00467-019-04456-8","type":"journal-article","created":{"date-parts":[[2020,1,2]],"date-time":"2020-01-02T12:37:51Z","timestamp":1577968671000},"page":"259-269","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["One size does not fit all: understanding individual living kidney donor risk"],"prefix":"10.1007","volume":"36","author":[{"given":"Elham","family":"Asgari","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5118-2017","authenticated-orcid":false,"given":"Rachel M.","family":"Hilton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,1,2]]},"reference":[{"issue":"suppl","key":"4456_CR1","first-page":"55","volume":"53","author":"A Tarantino","year":"2000","unstructured":"Tarantino A (2000) Why should we implement living donation in renal transplantation? Clin Nephrol 53(suppl):55\u201363","journal-title":"Clin Nephrol"},{"key":"4456_CR2","first-page":"167","volume":"67","author":"WR Guild","year":"1955","unstructured":"Guild WR, Harrison JH, Merrill JP, Murray J (1955) Successful homotransplantation of the kidney in an identical twin. Trans Am Clin Climatol Assoc 67:167\u2013173","journal-title":"Trans Am Clin Climatol Assoc"},{"key":"4456_CR3","unstructured":"NHS Blood and Transplant. Living donor kidney transplantation 2020: A UK strategy 2014. www.odt.nhs.uk\/pdf\/ldkt_2020_strategy.pdf. Accessed May 2019"},{"key":"4456_CR4","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1111\/ajt.13687","volume":"16","author":"KL Lentine","year":"2016","unstructured":"Lentine KL, Lam NN, Axelrod D, Schnitzler MA, Garg AX, Xiao H, Dzebisashvili N, Schold JD, Brennan DC, Randall H, King EA, Segev DL (2016) Perioperative complications after living kidney donation: a National Study. Am J Transplant 16:1848\u20131857","journal-title":"Am J Transplant"},{"key":"4456_CR5","doi-asserted-by":"crossref","first-page":"2264","DOI":"10.1097\/TP.0000000000001327","volume":"100","author":"K Kortram","year":"2016","unstructured":"Kortram K, Ijzermans JN, Dor FJ (2016) Perioperative events and complications in minimally invasive live donor nephrectomy: a systematic review and meta-analysis. Transplantation 100:2264\u20132275","journal-title":"Transplantation"},{"key":"4456_CR6","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1001\/jama.2010.237","volume":"303","author":"DL Segev","year":"2010","unstructured":"Segev DL, Muzaale AD, Caffo BS, Mehta SH, Singer AL, Taranto SE, McBride MA, Montgomery RA (2010) Perioperative mortality and long-term survival following live kidney donation. JAMA 303:959\u2013966","journal-title":"JAMA"},{"key":"4456_CR7","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1056\/NEJM199402103300607","volume":"330","author":"CA Steiner","year":"1994","unstructured":"Steiner CA, Bass EB, Talamini MA, Pitt HA, Steinberg EP (1994) Surgical rates and operative mortality for open and laparoscopic cholecystectomy in Maryland. N Engl J Med 330:403\u2013408","journal-title":"N Engl J Med"},{"key":"4456_CR8","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1056\/NEJMsa012337","volume":"346","author":"JD Birkmeyer","year":"2002","unstructured":"Birkmeyer JD, Siewers AE, Finlayson EV, Stukel TA, Lucas FL, Batista I, Welch HG, Wennberg DE (2002) Hospital volume and surgical mortality in the United States. N Engl J Med 346:1128\u20131137","journal-title":"N Engl J Med"},{"key":"4456_CR9","doi-asserted-by":"crossref","first-page":"e1203","DOI":"10.1136\/bmj.e1203","volume":"344","author":"AX Garg","year":"2012","unstructured":"Garg AX, Meirambayeva A, Huang A, Kim J, Prasad GV, Knoll G, Boudville N, Lok C, McFarlane P, Karpinski M, Storsley L, Klarenbach S, Lam N, Thomas SM, Dipchand C, Reese P, Doshi M, Gibney E, Taub K, Young A, Donor Nephrectomy Outcomes Research Network (2012) Cardiovascular disease in kidney donors: matched cohort study. BMJ 344:e1203","journal-title":"BMJ"},{"key":"4456_CR10","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1097\/TP.0b013e318192dc95","volume":"87","author":"M Okamoto","year":"2009","unstructured":"Okamoto M, Akioka K, Nobori S, Ushigome H, Kozaki K, Kaihara S, Yoshimura N (2009) Short- and long-term donor outcomes after kidney donation: analysis of 601 cases over a 35-year period at Japanese single center. Transplantation 87:419\u2013423","journal-title":"Transplantation"},{"key":"4456_CR11","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1038\/ki.2013.460","volume":"86","author":"G Mj\u00f8en","year":"2014","unstructured":"Mj\u00f8en G, Hallan S, Hartmann A, Foss A, Midtvedt K, \u00d8yen O, Reis\u00e6ter A, Pfeffer P, Jenssen T, Leivestad T, Line PD, \u00d8vrehus M, Dale DO, Pihlstr\u00f8m H, Holme I, Dekker FW, Holdaas H (2014) Long-term risks for kidney donors. Kidney Int 86:162\u2013167","journal-title":"Kidney Int"},{"key":"4456_CR12","doi-asserted-by":"crossref","first-page":"276","DOI":"10.7326\/M17-1235","volume":"168","author":"LM O'Keeffe","year":"2018","unstructured":"O'Keeffe LM, Ramond A, Oliver-Williams C, Willeit P, Paige E, Trotter P, Evans J, Wadstr\u00f6m J, Nicholson M, Collett D, Di Angelantonio E (2018) Mid- and long-term health risks in living kidney donors: a systematic review and meta-analysis. Ann Intern Med 168:276\u2013284","journal-title":"Ann Intern Med"},{"key":"4456_CR13","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1001\/jama.2013.285141","volume":"311","author":"AD Muzaale","year":"2014","unstructured":"Muzaale AD, Massie AB, Wang MC, Montgomery RA, McBride MA, Wainright JL, Segev DL (2014) Risk of end-stage renal disease following live kidney donation. JAMA 311:579\u2013586","journal-title":"JAMA"},{"key":"4456_CR14","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1056\/NEJMoa1510491","volume":"374","author":"Grams ME, Sang Y, Levey AS, Matsushita K, Ballew S, Chang AR, Chow EK, Kasiske BL, Kovesdy CP, Nadkarni GN, Shalev V, Segev DL, Coresh J, Lentine KL, Garg AX; Chronic Kidney Disease Prognosis Consortium","year":"2016","unstructured":"Grams ME, Sang Y, Levey AS, Matsushita K, Ballew S, Chang AR, Chow EK, Kasiske BL, Kovesdy CP, Nadkarni GN, Shalev V, Segev DL, Coresh J, Lentine KL, Garg AX; Chronic Kidney Disease Prognosis Consortium (2016) Kidney-failure risk projection for the living kidney-donor candidate. N Engl J Med 374:411\u2013421","journal-title":"N Engl J Med"},{"key":"4456_CR15","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1111\/ajt.14671","volume":"18","author":"AJ Matas","year":"2018","unstructured":"Matas AJ, Berglund DM, Vock DM, Ibrahim HN (2018) Causes and timing of end-stage renal disease after living kidney donation. Am J Transplant 18:1140\u20131150","journal-title":"Am J Transplant"},{"key":"4456_CR16","unstructured":"Steiner RW (2019) \u201cYou can't get there from here\u201d: Critical obstacles to current estimates of the ESRD risks of young living kidney donors. Am J Transplant 19:32\u201336"},{"key":"4456_CR17","doi-asserted-by":"crossref","first-page":"2557","DOI":"10.1681\/ASN.2005020172","volume":"16","author":"WE Hoy","year":"2005","unstructured":"Hoy WE, Hughson MD, Bertram JF, Douglas-Denton R, Amann K (2005) Nephron number, hypertension, renal disease, and renal failure. J Am Soc Nephrol 16:2557\u20132564","journal-title":"J Am Soc Nephrol"},{"key":"4456_CR18","doi-asserted-by":"crossref","first-page":"2534","DOI":"10.1111\/ajt.14713","volume":"18","author":"OA Sanchez","year":"2018","unstructured":"Sanchez OA, Ferrara LK, Rein S, Berglund D, Matas AJ, Ibrahim HN (2018) Hypertension after kidney donation: incidence, predictors, and correlates. Am J Transplant 18:2534\u20132543","journal-title":"Am J Transplant"},{"key":"4456_CR19","doi-asserted-by":"crossref","first-page":"e010869","DOI":"10.1136\/bmjopen-2015-010869","volume":"6","author":"GT Thiel","year":"2016","unstructured":"Thiel GT, Nolte C, Tsinalis D, Steiger J, Bachmann LM (2016) Investigating kidney donation as a risk factor for hypertension and microalbuminuria: findings from the Swiss prospective follow-up of living kidney donors. BMJ Open 6:e010869","journal-title":"BMJ Open"},{"key":"4456_CR20","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1053\/j.ajkd.2015.01.019","volume":"66","author":"BL Kasiske","year":"2015","unstructured":"Kasiske BL, Anderson-Haag T, Israni AK, Kalil RS, Kimmel PL, Kraus ES, Kumar R, Posselt AA, Pesavento TE, Rabb H, Steffes MW, Snyder JJ, Weir MR (2015) A prospective controlled study of living kidney donors: three-year follow-up. Am J Kidney Dis 66:114\u2013124","journal-title":"Am J Kidney Dis"},{"key":"4456_CR21","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1111\/j.1600-6143.2012.04303.x","volume":"13","author":"MD Doshi","year":"2013","unstructured":"Doshi MD, Goggins MO, Li L, Garg AX (2013) Medical outcomes in African American live kidney donors: a matched cohort study. Am J Transplant 13:111\u2013118","journal-title":"Am J Transplant"},{"key":"4456_CR22","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1161\/HYPERTENSIONAHA.115.06608","volume":"67","author":"WE Moody","year":"2016","unstructured":"Moody WE, Ferro CJ, Edwards NC, Chue CD, Lin EL, Taylor RJ, Cockwell P, Steeds RP, Townend JN, CRIB-Donor Study Investigators (2016) Cardiovascular effects of unilateral nephrectomy in living kidney donors. Hypertension 67:368\u2013377","journal-title":"Hypertension"},{"key":"4456_CR23","doi-asserted-by":"crossref","first-page":"e50046","DOI":"10.1371\/journal.pone.0050046","volume":"7","author":"E Krishnan","year":"2012","unstructured":"Krishnan E (2012) Reduced glomerular function and prevalence of gout: NHANES 2009-10. PLoS One 7:e50046","journal-title":"PLoS One"},{"key":"4456_CR24","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1053\/j.ajkd.2013.01.027","volume":"62","author":"BL Kasiske","year":"2013","unstructured":"Kasiske BL, Anderson-Haag T, Ibrahim HN, Pesavento TE, Weir MR, Nogueira JM, Cosio FG, Kraus ES, Rabb HH, Kalil RS, Posselt AA, Kimmel PL, Steffes MW (2013) A prospective controlled study of kidney donors: baseline and 6-month follow-up. Am J Kidney Dis 62:577\u2013586","journal-title":"Am J Kidney Dis"},{"key":"4456_CR25","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1053\/j.ajkd.2015.01.017","volume":"65","author":"NN Lam","year":"2015","unstructured":"Lam NN, McArthur E, Kim SJ, Prasad GV, Lentine KL, Reese PP, Kasiske BL, Lok CE, Feldman LS, Garg AX, Donor Nephrectomy Outcomes Research (DONOR) Network (2015) Gout after living kidney donation: a matched cohort study. Am J Kidney Dis 65:925\u2013932","journal-title":"Am J Kidney Dis"},{"key":"4456_CR26","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1159\/000381291","volume":"41","author":"NN Lam","year":"2015","unstructured":"Lam NN, Garg AX, Segev DL, Schnitzler MA, Xiao H, Axelrod D, Brennan DC, Kasiske BL, Tuttle-Newhall JE, Lentine KL (2015) Gout after living kidney donation: correlations with demographic traits and renal complications. Am J Nephrol 41:231\u2013240","journal-title":"Am J Nephrol"},{"key":"4456_CR27","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1007\/s11926-012-0307-x","volume":"15","author":"JA Singh","year":"2013","unstructured":"Singh JA (2013) Racial and gender disparities among patients with gout. Curr Rheumatol Rep 15:307","journal-title":"Curr Rheumatol Rep"},{"key":"4456_CR28","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1093\/aje\/kwt299","volume":"179","author":"JW Maynard","year":"2014","unstructured":"Maynard JW, McAdams-DeMarco MA, Law A, Kao L, Gelber AC, Coresh J, Baer AN (2014) Racial differences in gout incidence in a population-based cohort: atherosclerosis risk in communities study. Am J Epidemiol 179:576\u2013583","journal-title":"Am J Epidemiol"},{"key":"4456_CR29","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1053\/j.ajkd.2011.09.019","volume":"59","author":"A Young","year":"2012","unstructured":"Young A, Hodsman AB, Boudville N, Geddes C, Gill J, Goltzman D, Jassal SV, Klarenbach S, Knoll G, Muirhead N, Prasad GV, Treleaven D, Garg AX, Donor Nephrectomy Outcomes Research (DONOR) Network (2012) Bone and mineral metabolism and fibroblast growth factor 23 levels after kidney donation. Am J Kidney Dis 59:761\u2013769","journal-title":"Am J Kidney Dis"},{"key":"4456_CR30","doi-asserted-by":"crossref","first-page":"3041","DOI":"10.1111\/ajt.13453","volume":"15","author":"L Wirken","year":"2015","unstructured":"Wirken L, van Middendorp H, Hooghof CW, Rovers MM, Hoitsma AJ, Hilbrands LB, Evers AW (2015) The course and predictors of health-related quality of life in living kidney donors: a systematic review and meta-analysis. Am J Transplant 15:3041\u20133054","journal-title":"Am J Transplant"},{"key":"4456_CR31","doi-asserted-by":"crossref","first-page":"2924","DOI":"10.1111\/ajt.12434","volume":"13","author":"CR Gross","year":"2013","unstructured":"Gross CR, Messersmith EE, Hong BA, Jowsey SG, Jacobs C, Gillespie BW, Taler SJ, Matas AJ, Leichtman A, Merion RM, Ibrahim HN, RELIVE Study Group (2013) Health-related quality of life in kidney donors from the last five decades: results from the RELIVE study. Am J Transplant 13:2924\u20132934","journal-title":"Am J Transplant"},{"key":"4456_CR32","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1097\/00007890-199804150-00009","volume":"65","author":"HM K\u00e4rrfelt","year":"1998","unstructured":"K\u00e4rrfelt HM, Berg UB, Lindblad FI, Tyd\u00e9n GE (1998) To be or not to be a living donor: questionnaire to parents of children who have undergone renal transplantation. Transplantation 65:915\u2013918","journal-title":"Transplantation"},{"key":"4456_CR33","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1034\/j.1399-3046.2000.00135.x","volume":"4","author":"HM K\u00e4rrfelt","year":"2000","unstructured":"K\u00e4rrfelt HM, Berg UB, Lindblad FI (2000) Renal transplantation in children: psychological and donation-related aspects from the parental perspective. Pediatr Transplant 4:305\u2013312","journal-title":"Pediatr Transplant"},{"key":"4456_CR34","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1111\/tri.12481","volume":"28","author":"K Thys","year":"2015","unstructured":"Thys K, Schwering KL, Siebelink M, Dobbels F, Borry P, Schotsmans P, Aujoulat I, ELPAT Pediatric Organ Donation and Transplantation Working Group (2015) Psychosocial impact of pediatric living-donor kidney and liver transplantation on recipients, donors, and the family: a systematic review. Transpl Int 28:270\u2013280","journal-title":"Transpl Int"},{"key":"4456_CR35","doi-asserted-by":"crossref","first-page":"41","DOI":"10.4045\/tidsskr.10.1403","volume":"132","author":"LC Buer","year":"2012","unstructured":"Buer LC, Hofmann BM (2012) How does kidney transplantation affect the relationship between donor and recipient? Tidsskr Nor Laegeforen 132:41\u201343","journal-title":"Tidsskr Nor Laegeforen"},{"key":"4456_CR36","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.eururo.2012.03.052","volume":"62","author":"CD Scales","year":"2012","unstructured":"Scales CD, Smith AC, Hanley JM, Saigal CS, Project UdiA (2012) Prevalence of kidney stones in the United States. Eur Urol 62:160\u2013165","journal-title":"Eur Urol"},{"key":"4456_CR37","first-page":"e86","volume":"12","author":"V Romero","year":"2010","unstructured":"Romero V, Akpinar H, Assimos DG (2010) Kidney stones: a global picture of prevalence, incidence, and associated risk factors. Rev Urol 12:e86\u2013e96","journal-title":"Rev Urol"},{"issue":"8","key":"4456_CR38","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.1093\/ndt\/gfq769","volume":"26","author":"EC Lorenz","year":"2011","unstructured":"Lorenz EC, Lieske JC, Vrtiska TJ et al (2011) Clinical characteristics of potential kidney donors with asymptomatic kidney stones. Nephrol Dial Transplant 26(8):2695\u20132700","journal-title":"Nephrol Dial Transplant"},{"key":"4456_CR39","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1111\/j.1464-410X.2012.11572.x","volume":"111","author":"J Olsburgh","year":"2013","unstructured":"Olsburgh J, Thomas K, Wong K, Bultitude M, Glass J, Rottenberg G, Silas L, Hilton R, Koffman G (2013) Incidental renal stones in potential live kidney donors: prevalence, assessment and donation, including role of ex vivo ureteroscopy. BJU Int 111:784\u2013792","journal-title":"BJU Int"},{"key":"4456_CR40","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1111\/j.1399-0012.2011.01567.x","volume":"26","author":"IK Kim","year":"2012","unstructured":"Kim IK, Tan JC, Lapasia J, Elihu A, Busque S, Melcher ML (2012) Incidental kidney stones: a single center experience with kidney donor selection. Clin Transpl 26:558\u2013563","journal-title":"Clin Transpl"},{"key":"4456_CR41","doi-asserted-by":"crossref","first-page":"2935","DOI":"10.1111\/ajt.12446","volume":"13","author":"SM Thomas","year":"2013","unstructured":"Thomas SM, Lam NN, Welk BK, Nguan C, Huang A, Nash DM, Prasad GV, Knoll GA, Koval JJ, Lentine KL, Kim SJ, Lok CE, Garg AX, Donor Nephrectomy Outcomes Research (DONOR) Network (2013) Risk of kidney stones with surgical intervention in living kidney donors. Am J Transplant 13:2935\u20132944","journal-title":"Am J Transplant"},{"key":"4456_CR42","unstructured":"Guidelines for Living Donor Kidney Transplantation (2018) https:\/\/bts.org.uk\/wp-content\/uploads\/2018\/07\/FINAL_LDKT-guidelines_June-2018.pdf Accessed May 2019"},{"key":"4456_CR43","unstructured":"American Society of Transplantation. Kidney donation for people with kidney stones. Live Donor Toolkit: Resources for Those Considering Live Donation. http:\/\/www.livedonortoolkit.com\/medical-toolkit\/kidney-donation-people-kidney-stones Accessed May 2019"},{"key":"4456_CR44","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/S0140-6736(14)60460-8","volume":"384","author":"M Ng","year":"2014","unstructured":"Ng M, Fleming T, Robinson M et al (2014) Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the global burden of disease study 2013. Lancet 384:766\u2013781","journal-title":"Lancet"},{"key":"4456_CR45","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/S0140-6736(09)60318-4","volume":"373","author":"G Whitlock","year":"2009","unstructured":"Prospective Studies Collaboration, Whitlock G, Lewington S, Sherliker P, Clarke R, Emberson J, Halsey J, Qizilbash N, Collins R, Peto R (2009) Body-mass index and cause-specific mortality in 900,000 adults: collaborative analyses of 57 prospective studies. Lancet 373:1083\u20131096","journal-title":"Lancet"},{"key":"4456_CR46","doi-asserted-by":"crossref","first-page":"21","DOI":"10.7326\/0003-4819-144-1-200601030-00006","volume":"144","author":"CY Hsu","year":"2006","unstructured":"Hsu CY, McCulloch CE, Iribarren C, Darbinian J, Go AS (2006) Body mass index and risk for end-stage renal disease. Ann Intern Med 144:21\u201328","journal-title":"Ann Intern Med"},{"key":"4456_CR47","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1016\/j.jamcollsurg.2008.08.022","volume":"207","author":"NT Nguyen","year":"2008","unstructured":"Nguyen NT, Magno CP, Lane KT, Hinojosa MW, Lane JS (2008) Association of hypertension, diabetes, dyslipidemia, and metabolic syndrome with obesity: findings from the National Health and nutrition examination survey, 1999 to 2004. J Am Coll Surg 207:928\u2013934","journal-title":"J Am Coll Surg"},{"key":"4456_CR48","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1111\/j.1600-6143.2005.00791.x","volume":"5","author":"JK Heimbach","year":"2005","unstructured":"Heimbach JK, Taler SJ, Prieto M, Cosio FG, Textor SC, Kudva YC, Chow GK, Ishitani MB, Larson TS, Stegall MD (2005) Obesity in living kidney donors: clinical characteristics and outcomes in the era of laparoscopic donor nephrectomy. Am J Transplant 5:1057\u20131064","journal-title":"Am J Transplant"},{"key":"4456_CR49","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.ijsu.2017.09.007","volume":"46","author":"LW Unger","year":"2017","unstructured":"Unger LW, Feka J, Sabler P, Rasoul-Rockenschaub S, Gy\u00f6ri G, Hofmann M, Schwarz C, Soliman T, B\u00f6hmig G, Kainz A, Salat A, Berlakovich GA (2017) High BMI and male sex as risk factor for increased short-term renal impairment in living kidney donors - retrospective analysis of 289 consecutive cases. Int J Surg 46:172\u2013177","journal-title":"Int J Surg"},{"key":"4456_CR50","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/j.surg.2018.07.015","volume":"164","author":"OK Serrano","year":"2018","unstructured":"Serrano OK, Sengupta B, Bangdiwala A, Vock DM, Dunn TB, Finger EB, Pruett TL, Matas AJ, Kandaswamy R (2018) Implications of excess weight on kidney donation: long-term consequences of donor nephrectomy in obese donors. Surgery 164:1071\u20131076","journal-title":"Surgery"},{"key":"4456_CR51","doi-asserted-by":"publisher","first-page":"E883","DOI":"10.3390\/jcm8060883","volume":"8","author":"MI Bellini","year":"2019","unstructured":"Bellini MI, Charalampidis S, Stratigos I, Dor FJMF, Papalois V (2019) The effect of Donors' demographic characteristics in renal function post-living kidney donation. Analysis of a UK single Centre cohort. J Clin med 8:E883. https:\/\/doi.org\/10.3390\/jcm8060883","journal-title":"J Clin med"},{"key":"4456_CR52","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1097\/TP.0b013e3181b27a17","volume":"88","author":"PP Reese","year":"2009","unstructured":"Reese PP, Feldman HI, Asch DA, Thomasson A, Shults J, Bloom RD (2009) Short-term outcomes for obese live kidney donors and their recipients. Transplantation 88:662\u2013671","journal-title":"Transplantation"},{"key":"4456_CR53","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1097\/TP.0000000000002411","volume":"103","author":"CM Holscher","year":"2019","unstructured":"Holscher CM, Bae S, Thomas AG, Henderson ML, Haugen CE, DiBrito SR, Muzaale AD, Garonzik Wang JM, Massie AB, Lentine KL, Segev DL (2019) Early hypertension and diabetes after living kidney donation: a National Cohort Study. Transplantation 103:1216\u20131223","journal-title":"Transplantation"},{"key":"4456_CR54","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/j.kint.2016.10.014","volume":"91","author":"JE Locke","year":"2017","unstructured":"Locke JE, Reed RD, Massie A, MacLennan PA, Sawinski D, Kumar V, Mehta S, Mannon RB, Gaston R, Lewis CE, Segev DL (2017) Obesity increases the risk of end-stage renal disease among living kidney donors. Kidney Int 91:699\u2013703","journal-title":"Kidney Int"},{"key":"4456_CR55","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.surg.2019.03.016","volume":"166","author":"JE Locke","year":"2019","unstructured":"Locke JE, Reed RD, Massie AB, MacLennan PA, Sawinski D, Kumar V, Snyder JJ, Carter AJ, Shelton BA, Mustian MN, Lewis CE, Segev DL (2019) Obesity and long-term mortality risk among living kidney donors. Surgery 166:205\u2013208","journal-title":"Surgery"},{"key":"4456_CR56","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1056\/NEJMoa1000950","volume":"363","author":"KL Lentine","year":"2010","unstructured":"Lentine KL, Schnitzler MA, Xiao H, Saab G, Salvalaggio PR, Axelrod D, Davis CL, Abbott KC, Brennan DC (2010) Racial variation in medical outcomes among living kidney donors. N Engl J Med 363:724\u2013732","journal-title":"N Engl J Med"},{"key":"4456_CR57","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1097\/TP.0000000000000733","volume":"99","author":"KL Lentine","year":"2015","unstructured":"Lentine KL, Schnitzler MA, Garg AX, Xiao H, Axelrod D, Tuttle-Newhall JE, Brennan DC, Segev DL (2015) Race, relationship and renal diagnoses after living kidney donation. Transplantation 99:1723\u20131729","journal-title":"Transplantation"},{"key":"4456_CR58","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.semnephrol.2015.04.008","volume":"35","author":"PD Dummer","year":"2015","unstructured":"Dummer PD, Limou S, Rosenberg AZ, Heymann J, Nelson G, Winkler CA, Kopp JB (2015) APOL1 kidney disease risk variants: an evolving landscape. Semin Nephrol 35:222\u2013236","journal-title":"Semin Nephrol"},{"key":"4456_CR59","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1681\/ASN.2017060658","volume":"29","author":"MD Doshi","year":"2018","unstructured":"Doshi MD, Ortigosa-Goggins M, Garg AX, Li L, Poggio ED, Winkler CA, Kopp JB (2018) Genotype and renal function of black living donors. J Am Soc Nephrol 29:1309\u20131316","journal-title":"J Am Soc Nephrol"},{"key":"4456_CR60","unstructured":"APOL1 Long-Term Kidney Transplantation Outcomes Network (APOLLO) Clinical Centers: (Collaborative U01), Bethesda, MD, National Institutes of Health. Published 2017"},{"key":"4456_CR61","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1111\/j.1600-6143.2008.02427.x","volume":"9","author":"AV Reisaeter","year":"2009","unstructured":"Reisaeter AV, R\u00f8islien J, Henriksen T, Irgens LM, Hartmann A (2009) Pregnancy and birth after kidney donation: the Norwegian experience. Am J Transplant 9:820\u2013824","journal-title":"Am J Transplant"},{"key":"4456_CR62","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1111\/j.1600-6143.2009.02548.x","volume":"9","author":"HN Ibrahim","year":"2009","unstructured":"Ibrahim HN, Akkina SK, Leister E, Gillingham K, Cordner G, Guo H, Bailey R, Rogers T, Matas AJ (2009) Pregnancy outcomes after kidney donation. Am J Transplant 9:825\u2013834","journal-title":"Am J Transplant"},{"key":"4456_CR63","first-page":"1469","volume":"372","author":"AX Garg","year":"2015","unstructured":"Garg AX, McArthur E, Lentine KL, Network DNORD (2015) Gestational hypertension and preeclampsia in living kidney donors. N Engl J Med 372:1469\u20131470","journal-title":"N Engl J Med"},{"key":"4456_CR64","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1111\/ajt.12822","volume":"14","author":"PP Reese","year":"2014","unstructured":"Reese PP, Bloom RD, Feldman HI, Rosenbaum P, Wang W, Saynisch P, Tarsi NM, Mukherjee N, Garg AX, Mussell A, Shults J, Even-Shoshan O, Townsend RR, Silber JH (2014) Mortality and cardiovascular disease among older live kidney donors. Am J Transplant 14:1853\u20131861","journal-title":"Am J Transplant"},{"key":"4456_CR65","doi-asserted-by":"crossref","first-page":"2887","DOI":"10.2215\/CJN.04160511","volume":"6","author":"JC Berger","year":"2011","unstructured":"Berger JC, Muzaale AD, James N, Hoque M, Wang JM, Montgomery RA, Massie AB, Hall EC, Segev DL (2011) Living kidney donors ages 70 and older: recipient and donor outcomes. Clin J Am Soc Nephrol 6:2887\u20132893","journal-title":"Clin J Am Soc Nephrol"},{"key":"4456_CR66","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1111\/j.1600-6143.2011.03465.x","volume":"11","author":"LF Dols","year":"2011","unstructured":"Dols LF, Kok NF, Roodnat JI, Tran TC, Terkivatan T, Zuidema WC, Weimar W, Ijzermans JN (2011) Living kidney donors: impact of age on long-term safety. Am J Transplant 11:737\u2013742","journal-title":"Am J Transplant"}],"container-title":["Pediatric Nephrology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-019-04456-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00467-019-04456-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-019-04456-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,19]],"date-time":"2021-01-19T09:21:30Z","timestamp":1611048090000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00467-019-04456-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,2]]},"references-count":66,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["4456"],"URL":"https:\/\/doi.org\/10.1007\/s00467-019-04456-8","relation":{},"ISSN":["0931-041X","1432-198X"],"issn-type":[{"value":"0931-041X","type":"print"},{"value":"1432-198X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,2]]},"assertion":[{"value":"24 May 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 November 2019","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 December 2019","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 January 2020","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}