{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T20:30:31Z","timestamp":1791405031672,"version":"4.3.3"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T00:00:00Z","timestamp":1616457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T00:00:00Z","timestamp":1616457600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100010078","name":"Region Midtjylland","doi-asserted-by":"publisher","award":["A2352"],"award-info":[{"award-number":["A2352"]}],"id":[{"id":"10.13039\/501100010078","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Nephrol"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1007\/s00467-021-05042-7","type":"journal-article","created":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T01:02:46Z","timestamp":1616461366000},"page":"2777-2787","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Risk factors for kidney scarring and vesicoureteral reflux in 421 children after their first acute pyelonephritis, and appraisal of international guidelines"],"prefix":"10.1007","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8408-4381","authenticated-orcid":false,"given":"Anders","family":"Breinbjerg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3630-2329","authenticated-orcid":false,"given":"Cecilie Siggaard","family":"J\u00f8rgensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6206-8065","authenticated-orcid":false,"given":"J\u00f8rgen","family":"Fr\u00f8ki\u00e6r","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kjell","family":"Tullus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0104-4884","authenticated-orcid":false,"given":"Konstantinos","family":"Kamperis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7038-1652","authenticated-orcid":false,"given":"S\u00f8ren","family":"Rittig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,3,23]]},"reference":[{"key":"5042_CR1","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/s0022-3476(05)81531-8","volume":"123","author":"A Hoberman","year":"1993","unstructured":"Hoberman A, Chao HP, Keller DM, Hickey R, Davis HW, Ellis D (1993) Prevalence of urinary tract infection in febrile infants. J Pediatr 123:17\u201323. https:\/\/doi.org\/10.1016\/s0022-3476(05)81531-8","journal-title":"J Pediatr"},{"key":"5042_CR2","doi-asserted-by":"publisher","first-page":"e13","DOI":"10.1542\/peds.2015-0409","volume":"136","author":"R Keren","year":"2015","unstructured":"Keren R, Shaikh N, Pohl H, Gravens-Mueller L, Ivanova A, Zaoutis L, Patel M, deBerardinis R, Parker A, Bhatnagar S, Haralam MA, Pope M, Kearney D, Sprague B, Barrera R, Viteri B, Egigueron M, Shah N, Hoberman A (2015) Risk factors for recurrent urinary tract infection and renal scarring. Pediatrics 136:e13\u2013e21. https:\/\/doi.org\/10.1542\/peds.2015-0409","journal-title":"Pediatrics"},{"key":"5042_CR3","doi-asserted-by":"publisher","first-page":"1084","DOI":"10.1542\/peds.2010-0685","volume":"126","author":"N Shaikh","year":"2010","unstructured":"Shaikh N, Ewing AL, Bhatnagar S, Hoberman A (2010) Risk of renal scarring in children with a first urinary tract infection: a systematic review. Pediatrics 126:1084\u20131091. https:\/\/doi.org\/10.1542\/peds.2010-0685","journal-title":"Pediatrics"},{"key":"5042_CR4","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1067\/mpd.2003.13","volume":"142","author":"L Patzer","year":"2003","unstructured":"Patzer L, Seeman T, Luck C, Wuhl E, Janda J, Misselwitz J (2003) Day- and night-time blood pressure elevation in children with higher grades of renal scarring. J Pediatr 142:117\u2013122. https:\/\/doi.org\/10.1067\/mpd.2003.13","journal-title":"J Pediatr"},{"key":"5042_CR5","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1136\/bmj.39244.692442.55","volume":"335","author":"G Montini","year":"2007","unstructured":"Montini G, Toffolo A, Zucchetta P, Dall'Amico R, Gobber D, Calderan A, Maschio F, Pavanello L, Molinari PP, Scorrano D, Zanchetta S, Cassar W, Brisotto P, Corsini A, Sartori S, Da Dalt L, Murer L, Zacchello G (2007) Antibiotic treatment for pyelonephritis in children: multicentre randomised controlled non-inferiority trial. BMJ 335:386. https:\/\/doi.org\/10.1136\/bmj.39244.692442.55","journal-title":"BMJ"},{"key":"5042_CR6","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1001\/jamapediatrics.2014.637","volume":"168","author":"N Shaikh","year":"2014","unstructured":"Shaikh N, Craig JC, Rovers MM, Da Dalt L, Gardikis S, Hoberman A, Montini G, Rodrigo C, Taskinen S, Tuerlinckx D, Shope T (2014) Identification of children and adolescents at risk for renal scarring after a first urinary tract infection: a meta-analysis with individual patient data. JAMA Pediatr 168:893\u2013900. https:\/\/doi.org\/10.1001\/jamapediatrics.2014.637","journal-title":"JAMA Pediatr"},{"key":"5042_CR7","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1007\/s004670050535","volume":"12","author":"JM Smellie","year":"1998","unstructured":"Smellie JM, Prescod NP, Shaw PJ, Risdon RA, Bryant TN (1998) Childhood reflux and urinary infection: a follow-up of 10-41 years in 226 adults. Pediatr Nephrol 12:727\u2013736. https:\/\/doi.org\/10.1007\/s004670050535","journal-title":"Pediatr Nephrol"},{"key":"5042_CR8","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1046\/j.1464-410x.2000.00728.x","volume":"86","author":"EJ Kass","year":"2000","unstructured":"Kass EJ, Kernen KM, Carey JM (2000) Paediatric urinary tract infection and the necessity of complete urological imaging. BJU Int 86:94\u201396. https:\/\/doi.org\/10.1046\/j.1464-410x.2000.00728.x","journal-title":"BJU Int"},{"key":"5042_CR9","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1542\/peds.2011-1330","volume":"128","author":"KB Roberts","year":"2011","unstructured":"Roberts KB (2011) Urinary tract infection: clinical practice guideline for the diagnosis and management of the initial UTI in febrile infants and children 2 to 24 months. Pediatrics 128:595\u2013610. https:\/\/doi.org\/10.1542\/peds.2011-1330","journal-title":"Pediatrics"},{"key":"5042_CR10","unstructured":"National Institute for Health and Care Excellence (August 2007) Urinary tract infection in children. Available at: http:\/\/www.nice.org.uk\/CG54. Accessed 03 Feb\u00a02016"},{"key":"5042_CR11","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1016\/j.eururo.2014.11.007","volume":"67","author":"R Stein","year":"2015","unstructured":"Stein R, Dogan HS, Hoebeke P, Kocvara R, Nijman RJ, Radmayr C, Tekgul S (2015) Urinary tract infections in children: EAU\/ESPU guidelines. Eur Urol 67:546\u2013558. https:\/\/doi.org\/10.1016\/j.eururo.2014.11.007","journal-title":"Eur Urol"},{"key":"5042_CR12","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1111\/apa.14988","volume":"109","author":"A Ammenti","year":"2020","unstructured":"Ammenti A, Alberici I, Brugnara M, Chimenz R, Guarino S, La Manna A, La Scola C, Maringhini S, Marra G, Materassi M, Morello W, Nicolini G, Pennesi M, Pisanello L, Pugliese F, Scozzola F, Sica F, Toffolo A, Montini G (2020) Updated Italian recommendations for the diagnosis, treatment and follow-up of the first febrile urinary tract infection in young children. Acta Paediatr 109:236\u2013247. https:\/\/doi.org\/10.1111\/apa.14988","journal-title":"Acta Paediatr"},{"key":"5042_CR13","doi-asserted-by":"publisher","first-page":"1253","DOI":"10.1007\/s00467-015-3168-5","volume":"31","author":"W Morello","year":"2016","unstructured":"Morello W, La Scola C, Alberici I, Montini G (2016) Acute pyelonephritis in children. Pediatr Nephrol 31:1253\u20131265. https:\/\/doi.org\/10.1007\/s00467-015-3168-5","journal-title":"Pediatr Nephrol"},{"key":"5042_CR14","doi-asserted-by":"publisher","first-page":"1018","DOI":"10.1111\/j.1651-2227.2012.02785.x","volume":"101","author":"A Toffolo","year":"2012","unstructured":"Toffolo A, Ammenti A, Montini G (2012) Long-term clinical consequences of urinary tract infections during childhood: a review. Acta Paediatr 101:1018\u20131031. https:\/\/doi.org\/10.1111\/j.1651-2227.2012.02785.x","journal-title":"Acta Paediatr"},{"key":"5042_CR15","doi-asserted-by":"publisher","first-page":"1064","DOI":"10.1542\/peds.2007-3770","volume":"122","author":"G Montini","year":"2008","unstructured":"Montini G, Rigon L, Zucchetta P, Fregonese F, Toffolo A, Gobber D, Cecchin D, Pavanello L, Molinari PP, Maschio F, Zanchetta S, Cassar W, Casadio L, Crivellaro C, Fortunati P, Corsini A, Calderan A, Comacchio S, Tommasi L, Hewitt IK, Da Dalt L, Zacchello G, Dall'Amico R (2008) Prophylaxis after first febrile urinary tract infection in children? A multicenter, randomized, controlled, noninferiority trial. Pediatrics 122:1064\u20131071. https:\/\/doi.org\/10.1542\/peds.2007-3770","journal-title":"Pediatrics"},{"key":"5042_CR16","doi-asserted-by":"publisher","first-page":"e1489","DOI":"10.1542\/peds.2007-2652","volume":"121","author":"M Pennesi","year":"2008","unstructured":"Pennesi M, Travan L, Peratoner L, Bordugo A, Cattaneo A, Ronfani L, Minisini S, Ventura A (2008) Is antibiotic prophylaxis in children with vesicoureteral reflux effective in preventing pyelonephritis and renal scars? A randomized, controlled trial. Pediatrics 121:e1489\u2013e1494. https:\/\/doi.org\/10.1542\/peds.2007-2652","journal-title":"Pediatrics"},{"key":"5042_CR17","doi-asserted-by":"publisher","first-page":"2367","DOI":"10.1056\/NEJMoa1401811","volume":"370","author":"A Hoberman","year":"2014","unstructured":"Hoberman A, Greenfield SP, Mattoo TK, Keren R, Mathews R, Pohl HG, Kropp BP, Skoog SJ, Nelson CP, Moxey-Mims M, Chesney RW, Carpenter MA (2014) Antimicrobial prophylaxis for children with vesicoureteral reflux. N Engl J Med 370:2367\u20132376. https:\/\/doi.org\/10.1056\/NEJMoa1401811","journal-title":"N Engl J Med"},{"key":"5042_CR18","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1016\/j.juro.2010.01.061","volume":"184","author":"P Brandstrom","year":"2010","unstructured":"Brandstrom P, Esbjorner E, Herthelius M, Swerkersson S, Jodal U, Hansson S (2010) The Swedish reflux trial in children: III. Urinary tract infection pattern. J Urol 184:286\u2013291. https:\/\/doi.org\/10.1016\/j.juro.2010.01.061","journal-title":"J Urol"},{"key":"5042_CR19","first-page":"5775","volume":"161","author":"A Hansen","year":"1999","unstructured":"Hansen A, Andersen KV, Cortes D, Nathan E, Nielsen OH (1999) A reference program for children with urinary tract infection. A proposal for diagnosis and treatment of children with urinary tract infection. Ugeskr Laeger 161:5775\u20135777","journal-title":"Ugeskr Laeger"},{"key":"5042_CR20","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1046\/j.1198-743x.2001.00237.x","volume":"7","author":"O Aspevall","year":"2001","unstructured":"Aspevall O, Hallander H, Gant V, Kouri T (2001) European guidelines for urinalysis: a collaborative document produced by European clinical microbiologists and clinical chemists under ECLM in collaboration with ESCMID. Clin Microbiol Infect 7:173\u2013178. https:\/\/doi.org\/10.1046\/j.1198-743x.2001.00237.x","journal-title":"Clin Microbiol Infect"},{"key":"5042_CR21","doi-asserted-by":"crossref","unstructured":"(1981) Medical versus surgical treatment of primary vesicoureteral reflux: report of the International Reflux Study Committee. Pediatrics 67:392\u2013400","DOI":"10.1542\/peds.67.3.392"},{"key":"5042_CR22","unstructured":"Storby KA, Lund; Brandstr\u00f6m P, G\u00f6teborg; Hansson S, G\u00f6teborg; Herthelius M, Stockholm; Nev\u00e9us T, Uppsala; Rundqvist S, J\u00f6nk\u00f6ping; Swerkersson S, Sk\u00f6vde; Wennerstr\u00f6m M, G\u00f6teborg (2013) Urinv\u00e4gsinfektion (UVI) hos barn. http:\/\/nefro.barnlakarforeningen.se\/vardprogram\/urinvagsinfektioner-hos-barn-uvi\/. Accessed October 2019"},{"key":"5042_CR23","doi-asserted-by":"publisher","first-page":"1176","DOI":"10.1111\/apa.13894","volume":"106","author":"G Mola","year":"2017","unstructured":"Mola G, Wenger TR, Salomonsson P, Knudsen IJD, Madsen JL, Moller S, Olsen BH, Vinicoff PG, Thorup J, Cortes D (2017) Selective imaging modalities after first pyelonephritis failed to identify significant urological anomalies, despite normal antenatal ultrasounds. Acta Paediatr 106:1176\u20131183. https:\/\/doi.org\/10.1111\/apa.13894","journal-title":"Acta Paediatr"},{"key":"5042_CR24","doi-asserted-by":"publisher","first-page":"419","DOI":"10.3109\/21681805.2015.1009485","volume":"49","author":"MT Ristola","year":"2015","unstructured":"Ristola MT, Hurme T (2015) Consequences of following the new American Academy of Pediatrics guidelines for imaging children with urinary tract infection. Scand J Urol 49:419\u2013423. https:\/\/doi.org\/10.3109\/21681805.2015.1009485","journal-title":"Scand J Urol"},{"key":"5042_CR25","doi-asserted-by":"publisher","first-page":"e665","DOI":"10.1542\/peds.2012-0164","volume":"131","author":"C La Scola","year":"2013","unstructured":"La Scola C, De Mutiis C, Hewitt IK, Puccio G, Toffolo A, Zucchetta P, Mencarelli F, Marsciani M, Dall'Amico R, Montini G (2013) Different guidelines for imaging after first UTI in febrile infants: yield, cost, and radiation. Pediatrics 131:e665\u2013e671. https:\/\/doi.org\/10.1542\/peds.2012-0164","journal-title":"Pediatrics"},{"key":"5042_CR26","doi-asserted-by":"publisher","first-page":"1119","DOI":"10.1177\/0009922813515744","volume":"53","author":"S Roupakias","year":"2014","unstructured":"Roupakias S, Sinopidis X, Karatza A, Varvarigou A (2014) Predictive risk factors in childhood urinary tract infection, vesicoureteral reflux, and renal scarring management. Clin Pediatr (Phila) 53:1119\u20131133. https:\/\/doi.org\/10.1177\/0009922813515744","journal-title":"Clin Pediatr (Phila)"},{"key":"5042_CR27","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1111\/apa.14506","volume":"108","author":"I Alberici","year":"2019","unstructured":"Alberici I, La Manna A, Pennesi M, Starc M, Scozzola F, Nicolini G, Toffolo A, Marra G, Chimenz R, Sica F, Maringhini S, Monasta L, Montini G (2019) First urinary tract infections in children: the role of the risk factors proposed by the Italian recommendations. Acta Paediatr 108:544\u2013550. https:\/\/doi.org\/10.1111\/apa.14506","journal-title":"Acta Paediatr"},{"key":"5042_CR28","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.1016\/s0140-6736(81)92797-5","volume":"2","author":"G K\u00e4llenius","year":"1981","unstructured":"K\u00e4llenius G, M\u00f6llby R, Svenson SB, Helin I, Hultberg H, Cedergren B, Winberg J (1981) Occurrence of P-fimbriated Escherichia coli in urinary tract infections. Lancet 2:1369\u20131372. https:\/\/doi.org\/10.1016\/s0140-6736(81)92797-5","journal-title":"Lancet"},{"key":"5042_CR29","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1136\/archdischild-2018-315023","volume":"104","author":"K Tullus","year":"2019","unstructured":"Tullus K (2019) Fifteen-minute consultation: why and how do children get urinary tract infections? Arch Dis Child Educ Pract Ed 104:244\u2013247. https:\/\/doi.org\/10.1136\/archdischild-2018-315023","journal-title":"Arch Dis Child Educ Pract Ed"},{"key":"5042_CR30","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1056\/NEJMoa021698","volume":"348","author":"A Hoberman","year":"2003","unstructured":"Hoberman A, Charron M, Hickey RW, Baskin M, Kearney DH, Wald ER (2003) Imaging studies after a first febrile urinary tract infection in young children. N Engl J Med 348:195\u2013202. https:\/\/doi.org\/10.1056\/NEJMoa021698","journal-title":"N Engl J Med"},{"key":"5042_CR31","doi-asserted-by":"publisher","first-page":"e394","DOI":"10.1542\/peds.2013-2109","volume":"133","author":"CP Nelson","year":"2014","unstructured":"Nelson CP, Johnson EK, Logvinenko T, Chow JS (2014) Ultrasound as a screening test for genitourinary anomalies in children with UTI. Pediatrics 133:e394\u2013e403. https:\/\/doi.org\/10.1542\/peds.2013-2109","journal-title":"Pediatrics"},{"key":"5042_CR32","doi-asserted-by":"publisher","first-page":"CD010657","DOI":"10.1002\/14651858.CD010657.pub2","volume":"7","author":"N Shaikh","year":"2016","unstructured":"Shaikh N, Spingarn RB, Hum SW (2016) Dimercaptosuccinic acid scan or ultrasound in screening for vesicoureteral reflux among children with urinary tract infections. Cochrane Database Syst Rev 7:CD010657. https:\/\/doi.org\/10.1002\/14651858.CD010657.pub2","journal-title":"Cochrane Database Syst Rev"},{"key":"5042_CR33","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/s0022-3476(00)90045-3","volume":"136","author":"M Wennerstrom","year":"2000","unstructured":"Wennerstrom M, Hansson S, Jodal U, Stokland E (2000) Primary and acquired renal scarring in boys and girls with urinary tract infection. J Pediatr 136:30\u201334. https:\/\/doi.org\/10.1016\/s0022-3476(00)90045-3","journal-title":"J Pediatr"},{"key":"5042_CR34","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1001\/archpedi.154.4.339","volume":"154","author":"M Wennerstr\u00f6m","year":"2000","unstructured":"Wennerstr\u00f6m M, Hansson S, Jodal U, Sixt R, Stokland E (2000) Renal function 16 to 26 years after the first urinary tract infection in childhood. Arch Pediatr Adolesc Med 154:339\u2013345. https:\/\/doi.org\/10.1001\/archpedi.154.4.339","journal-title":"Arch Pediatr Adolesc Med"},{"key":"5042_CR35","doi-asserted-by":"publisher","first-page":"1493","DOI":"10.1007\/s00467-015-3084-8","volume":"30","author":"C Geb\u00e4ck","year":"2015","unstructured":"Geb\u00e4ck C, Hansson S, Martinell J, Sandberg T, Sixt R, Jodal U (2015) Renal function in adult women with urinary tract infection in childhood. Pediatr Nephrol 30:1493\u20131499. https:\/\/doi.org\/10.1007\/s00467-015-3084-8","journal-title":"Pediatr Nephrol"},{"key":"5042_CR36","first-page":"142","volume":"108","author":"Y Zhang","year":"1995","unstructured":"Zhang Y, Bailey RR (1995) A long term follow up of adults with reflux nephropathy. N Z Med J 108:142\u2013144","journal-title":"N Z Med J"},{"key":"5042_CR37","first-page":"50","volume":"41","author":"M el-Khatib","year":"1994","unstructured":"el-Khatib M, Packham DK, Becker GJ, Kincaid-Smith P (1994) Pregnancy-related complications in women with reflux nephropathy. Clin Nephrol 41:50\u201355","journal-title":"Clin Nephrol"},{"key":"5042_CR38","doi-asserted-by":"publisher","first-page":"1463","DOI":"10.1007\/s00467-010-1542-x","volume":"25","author":"A Hannula","year":"2010","unstructured":"Hannula A, Venhola M, Renko M, Pokka T, Huttunen NP, Uhari M (2010) Vesicoureteral reflux in children with suspected and proven urinary tract infection. Pediatr Nephrol 25:1463\u20131469. https:\/\/doi.org\/10.1007\/s00467-010-1542-x","journal-title":"Pediatr Nephrol"},{"key":"5042_CR39","doi-asserted-by":"publisher","first-page":"1875","DOI":"10.1111\/j.1651-2227.2010.01909.x","volume":"99","author":"M Venhola","year":"2010","unstructured":"Venhola M, Hannula A, Huttunen NP, Renko M, Pokka T, Uhari M (2010) Occurrence of vesicoureteral reflux in children. Acta Paediatr 99:1875\u20131878. https:\/\/doi.org\/10.1111\/j.1651-2227.2010.01909.x","journal-title":"Acta Paediatr"},{"key":"5042_CR40","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1001\/archpedi.152.9.879","volume":"152","author":"M Wennerstrom","year":"1998","unstructured":"Wennerstrom M, Hansson S, Jodal U, Stokland E (1998) Disappearance of vesicoureteral reflux in children. Arch Pediatr Adolesc Med 152:879\u2013883. https:\/\/doi.org\/10.1001\/archpedi.152.9.879","journal-title":"Arch Pediatr Adolesc Med"},{"key":"5042_CR41","doi-asserted-by":"publisher","first-page":"1071","DOI":"10.1097\/01.ju.0000135337.71154.60","volume":"172","author":"S Hansson","year":"2004","unstructured":"Hansson S, Dhamey M, Sigstrom O, Sixt R, Stokland E, Wennerstrom M, Jodal U (2004) Dimercapto-succinic acid scintigraphy instead of voiding cystourethrography for infants with urinary tract infection. J Urol 172:1071\u20131073; discussion 1073-1074. https:\/\/doi.org\/10.1097\/01.ju.0000135337.71154.60","journal-title":"J Urol"},{"key":"5042_CR42","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1007\/s00431-019-03324-9","volume":"178","author":"V Garc\u00eda-Nieto","year":"2019","unstructured":"Garc\u00eda-Nieto V, Garc\u00eda-Rodr\u00edguez VE, Luis-Yanes MI, Monge M, Arango-Sancho P, Garin EH (2019) Renal tubular markers as screening tools for severe vesicoureteral reflux. Eur J Pediatr 178:525\u2013531. https:\/\/doi.org\/10.1007\/s00431-019-03324-9","journal-title":"Eur J Pediatr"}],"container-title":["Pediatric Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-021-05042-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00467-021-05042-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-021-05042-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T05:05:25Z","timestamp":1671685525000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00467-021-05042-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,23]]},"references-count":42,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["5042"],"URL":"https:\/\/doi.org\/10.1007\/s00467-021-05042-7","relation":{},"ISSN":["0931-041X","1432-198X"],"issn-type":[{"value":"0931-041X","type":"print"},{"value":"1432-198X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,23]]},"assertion":[{"value":"4 December 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 February 2021","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 March 2021","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 March 2021","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was conducted with approval from the Danish Patient Safety Authority (number 3-3013-2075\/1), and the Danish Data Protection Agency (number 2012-58-006) under the Central Region of Denmark. The study was conducted in accordance with the declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"The authors declare that there are no conflicts of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}