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For genetic analyses, informed consent was obtained from all patients or their parents\/legal guardians.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Consent for publication was waived in accordance with the guidelines.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"All authors declare no conflicts of interest concerning the present study. Koichi Kamei has received research funding from the Terumo Foundation for Life Sciences and Arts, and donations from Ono Pharmaceutical Co., Ltd. Kenji Ishikura has received grants from Asahi Kasei Pharma Corporation, Chugai Pharmaceutical Co., Ltd., Novartis International AG, Zenyaku Kogyo Co., Ltd., Japan Blood Products Organization, Otsuka Pharmaceutical Co., Ltd., Teijin Pharma Limited, Shionogi Co., Ltd., Eisai Co., Ltd., Astellas Pharma Inc., and JCR Pharmaceuticals Co., Ltd., and lecture fees from Asahi Kasei Pharma Corporation, Chugai Pharmaceutical Co., Ltd., Novartis International AG, Zenyaku Kogyo Co. Ltd., Otsuka Pharmaceutical Co., Ltd., Alexion Pharmaceuticals Inc., and Pfizer Inc., and consultant fees from Alexion Pharmaceuticals Inc. and Vifor Pharma Management Ltd. Shuichi Ito has received employment from Teijin Pharma Ltd., Honoraria from Sanofi K.K., and research funding from Teijin Pharma Ltd. and Astellas Pharma Co., Ltd. The other authors have no potential conflicts of interest to disclose.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}