{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T05:20:35Z","timestamp":1789017635937,"version":"build-2803163510"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2022,1,18]],"date-time":"2022-01-18T00:00:00Z","timestamp":1642464000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,1,18]],"date-time":"2022-01-18T00:00:00Z","timestamp":1642464000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Nephrol"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1007\/s00467-021-05402-3","type":"journal-article","created":{"date-parts":[[2022,1,18]],"date-time":"2022-01-18T10:03:27Z","timestamp":1642500207000},"page":"2119-2126","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Defining kidney outcomes in children with acute lymphoblastic leukemia in the modern era"],"prefix":"10.1007","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2293-0319","authenticated-orcid":false,"given":"Reeti","family":"Kumar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanne","family":"Reed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph R.","family":"Stanek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John D.","family":"Mahan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,1,18]]},"reference":[{"key":"5402_CR1","doi-asserted-by":"publisher","first-page":"1541","DOI":"10.1056\/NEJMra1400972","volume":"373","author":"SP Hunger","year":"2015","unstructured":"Hunger SP, Mullighan CG (2015) Acute lymphoblastic leukemia in children. N Engl J Med 373:1541\u20131552","journal-title":"N Engl J Med"},{"key":"5402_CR2","doi-asserted-by":"publisher","first-page":"7","DOI":"10.3322\/caac.21387","volume":"67","author":"RL Siegel","year":"2017","unstructured":"Siegel RL, Miller KD, Jemal A (2017) Cancer statistics, 2017. CA Cancer J Clin 67:7\u201330","journal-title":"CA Cancer J Clin"},{"key":"5402_CR3","doi-asserted-by":"publisher","first-page":"5515","DOI":"10.1182\/blood-2007-10-117150","volume":"111","author":"R Mody","year":"2008","unstructured":"Mody R, Li S, Dover DC, Sallan S, Leisenring W, Oeffinger KC, Yasui Y, Robison LL, Neglia JP (2008) Twenty-five-year follow-up among survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study. Blood 111:5515\u20135523","journal-title":"Blood"},{"key":"5402_CR4","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1002\/ajh.20146","volume":"77","author":"S Yetgin","year":"2004","unstructured":"Yetgin S, Olgar S, Aras T, Cetin M, D\u00fczova A, Beylergil V, Akhan O, O\u011duz O, Sara\u00e7ba\u015fi O (2004) Evaluation of kidney damage in patients with acute lymphoblastic leukemia in long-term follow-up: value of renal scan. Am J Hematol 77:132\u2013139","journal-title":"Am J Hematol"},{"key":"5402_CR5","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1053\/j.ackd.2013.07.004","volume":"21","author":"RL Luciano","year":"2014","unstructured":"Luciano RL, Brewster UC (2014) Kidney Involvement in Leukemia and Lymphoma. Adv Chronic Kidney Dis 21:27\u201335","journal-title":"Adv Chronic Kidney Dis"},{"key":"5402_CR6","doi-asserted-by":"publisher","first-page":"782","DOI":"10.1007\/s00467-005-1839-3","volume":"20","author":"M Krawczuk-Rybak","year":"2005","unstructured":"Krawczuk-Rybak M, Ku\u017amicz M, Wysocka J (2005) Renal function during and after treatment for acute lymphoblastic leukemia in children. Pediatr Nephrol 20:782\u2013785","journal-title":"Pediatr Nephrol"},{"key":"5402_CR7","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1111\/j.1651-2227.1989.tb17945.x","volume":"78","author":"L Hovi","year":"1989","unstructured":"Hovi L, Koskimies O, Holmberg C, Rajantie J, Rautonen J, Siimes MA (1989) Risk of progressive kidney damage after acute leukemia. Acta Paediatr Scand 78:608\u2013614","journal-title":"Acta Paediatr Scand"},{"key":"5402_CR8","doi-asserted-by":"publisher","first-page":"2047","DOI":"10.1007\/s00467-017-3870-6","volume":"33","author":"VK Sigurjonsdottir","year":"2018","unstructured":"Sigurjonsdottir VK, Chaturvedi S, Mammen C, Sutherland SM (2018) Pediatric acute kidney injury and the subsequent risk for chronic kidney disease: is there cause for alarm? Pediatr Nephrol 33:2047\u20132055","journal-title":"Pediatr Nephrol"},{"key":"5402_CR9","doi-asserted-by":"publisher","first-page":"519","DOI":"10.3109\/08880019409141690","volume":"11","author":"SP Attard-Montalto","year":"1994","unstructured":"Attard-Montalto SP, Saha V, Ng YY, Kingston JE, Eden OB (1994) High incidence of hypertension in children presenting with acute lymphoblastic leukemia. Pediatr Hematol Oncol 11:519\u2013525","journal-title":"Pediatr Hematol Oncol"},{"key":"5402_CR10","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1007\/s00467-007-0720-y","volume":"23","author":"CU Louis","year":"2008","unstructured":"Louis CU, Butani L (2008) High blood pressure and hypertension in children with newly diagnosed acute leukemia and lymphoma. Pediatr Nephrol 23:603\u2013609","journal-title":"Pediatr Nephrol"},{"key":"5402_CR11","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1097\/01.mph.0000212990.64435.b9","volume":"28","author":"S Olgar","year":"2006","unstructured":"Olgar S, Yetgin S, Cetin M, Aras T (2006) Can renal leukemic infiltration cause hypertension in children? J Pediatr Hematol Oncol 28:579\u2013584","journal-title":"J Pediatr Hematol Oncol"},{"key":"5402_CR12","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1097\/MPH.0000000000000997","volume":"40","author":"I Bakk","year":"2018","unstructured":"Bakk I, Koch T, Stanek J, O\u2019Brien SH, Reed S (2018) Steroid-induced hypertension during induction chemotherapy for acute lymphoblastic leukemia in US Children\u2019s Hospitals. J Pediatr Hematol Oncol 40:27\u201330","journal-title":"J Pediatr Hematol Oncol"},{"key":"5402_CR13","doi-asserted-by":"publisher","first-page":"2313","DOI":"10.1002\/cncr.23050","volume":"110","author":"EJ Chow","year":"2007","unstructured":"Chow EJ, Pihoker C, Hunt K, Wilkinson K, Friedman DL (2007) Obesity and hypertension among children after treatment for acute lymphoblastic leukemia. Cancer 110:2313\u20132320","journal-title":"Cancer"},{"key":"5402_CR14","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1016\/S1470-2045(14)70265-7","volume":"15","author":"S Essig","year":"2014","unstructured":"Essig S, Li Q, Chen Y, Hitzler J, Leisenring W, Greenberg M, Sklar C, Hudson MM, Armstrong GT, Krull KR, Neglia JP, Oeffinger KC, Robison LL, Kuehni CE, Yasui Y, Nathan PC (2014) Risk of late effects of treatment in children newly diagnosed with standard-risk acute lymphoblastic leukaemia: a report from the Childhood Cancer Survivor Study cohort. Lancet Oncol 15:841\u2013851","journal-title":"Lancet Oncol"},{"key":"5402_CR15","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1053\/j.ajkd.2010.02.337","volume":"55","author":"AS Levey","year":"2010","unstructured":"Levey AS, Stevens LA (2010) Estimating GFR using the CKD Epidemiology Collaboration (CKD-EPI) creatinine equation: more accurate GFR estimates, lower CKD prevalence estimates, and better risk predictions. Am J Kidney Dis 55:622\u2013627","journal-title":"Am J Kidney Dis"},{"key":"5402_CR16","doi-asserted-by":"publisher","first-page":"2321","DOI":"10.1007\/s00467-010-1598-7","volume":"25","author":"A Staples","year":"2010","unstructured":"Staples A, LeBlond R, Watkins S, Wong C, Brandt J (2010) Validation of the revised Schwartz estimating equation in a predominantly non-CKD population. Pediatr Nephrol 25:2321\u20132326","journal-title":"Pediatr Nephrol"},{"key":"5402_CR17","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/kisup.2012.1","volume":"2","author":"KDIGO AKI Working Group","year":"2012","unstructured":"KDIGO AKI Working Group (2012) KDIGO clinical practice guideline for acute kidney injury. Kidney Int Suppl 2:1\u2013138","journal-title":"Kidney Int Suppl"},{"key":"5402_CR18","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1053\/j.ajkd.2014.01.416","volume":"63","author":"LA Inker","year":"2014","unstructured":"Inker LA, Astor BC, Fox CH, Isakova T, Lash JP, Peralta CA, Kurella Tamura M, Feldman HI (2014) KDOQI US commentary on the 2012 KDIGO clinical practice guideline for the evaluation and management of CKD. Am Journal Kidney Dis 63:713\u2013735","journal-title":"Am Journal Kidney Dis"},{"key":"5402_CR19","doi-asserted-by":"publisher","first-page":"e20171904","DOI":"10.1542\/peds.2017-1904","volume":"140","author":"JT Flynn","year":"2017","unstructured":"Flynn JT, Kaelber DC, Baker-Smith CM, Blowey D, Carroll AE, Daniels SR, de Ferranti SD, Dionne JM, Falkner B, Flinn SK, Gidding SS, Goodwin C, Leu MG, Powers ME, Rea C, Samuels J, Simasek M, Thaker VV, Urbina EM, Subcommittee on screening and management of high blood pressure in children (2017) Clinical practice guideline for screening and management of high blood pressure in children and adolescents. Pediatrics 140:e20171904","journal-title":"Pediatrics"},{"key":"5402_CR20","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1186\/s40885-015-0031-8","volume":"21","author":"H Lee","year":"2015","unstructured":"Lee H, Kong YH, Kim KH, Huh J, Kang IS, Song J (2015) Left ventricular hypertrophy and diastolic function in children and adolescents with essential hypertension. Clin Hypertens 21:21","journal-title":"Clin Hypertens"},{"key":"5402_CR21","doi-asserted-by":"publisher","first-page":"130","DOI":"10.5492\/wjccm.v4.i2.130","volume":"4","author":"AE Mirrakhimov","year":"2015","unstructured":"Mirrakhimov AE, Voore P, Khan M, Ali AM (2015) Tumor lysis syndrome: a clinical review. World J Crit Care Med 4:130\u2013138","journal-title":"World J Crit Care Med"},{"key":"5402_CR22","doi-asserted-by":"publisher","first-page":"17684","DOI":"10.1038\/s41598-017-17716-0","volume":"7","author":"E Levy","year":"2017","unstructured":"Levy E, Samoilenko M, Morel S, England J, Amre D, Bertout L, Drouin S, Laverdi\u00e8re C, Krajinovic M, Sinnett D, Lefebvre G, Marcil V (2017) Cardiometabolic risk factors in childhood, adolescent and young adult survivors of acute lymphoblastic leukemia \u2013 a Petale cohort. Sci Rep 7:17684","journal-title":"Sci Rep"},{"key":"5402_CR23","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1111\/bjh.12754","volume":"165","author":"KA Nottage","year":"2014","unstructured":"Nottage KA, Ness KK, Li C, Srivastava D, Robison LL, Hudson MM (2014) Metabolic syndrome and cardiovascular risk among long-term survivors of acute lymphoblastic leukaemia - from the St. Jude lifetime cohort. Br J Haematol 165:364\u2013374","journal-title":"Br J Haematol"},{"key":"5402_CR24","doi-asserted-by":"publisher","first-page":"4442","DOI":"10.1182\/blood-2010-09-304899","volume":"117","author":"C Oudin","year":"2011","unstructured":"Oudin C, Simeoni MC, Sirvent N, Contet A, Begu-Le Coroller A, Bordigoni P, Curtillet C, Poir\u00e9e M, Thuret I, Play B, Massot MC, Chastagner P, Chambost H, Auquier P, Michel G (2011) Prevalence and risk factors of the metabolic syndrome in adult survivors of childhood leukemia. Blood 117:4442\u20134448","journal-title":"Blood"},{"key":"5402_CR25","doi-asserted-by":"publisher","first-page":"1603","DOI":"10.3324\/haematol.2016.148908","volume":"101","author":"P Saultier","year":"2016","unstructured":"Saultier P, Auquier P, Bertrand Y, Vercasson C, Oudin C, Contet A, Plantaz D, Poir\u00e9e M, Ducassou S, Kanold J, Tabone MD, Dalle JH, Lutz P, Gandemer V, Sirvent N, Thouvenin S, Berbis J, Chambost H, Baruchel A, Leverger G, Michel G (2016) Metabolic syndrome in long-term survivors of childhood acute leukemia treated without hematopoietic stem cell transplantation: an L.E.A. study. Haematologica 101:1603\u20131610","journal-title":"Haematologica"},{"key":"5402_CR26","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1002\/pbc.23251","volume":"58","author":"SJ Veringa","year":"2012","unstructured":"Veringa SJ, van Dulmen-den BE, Kaspers GJ, Veening MA (2012) Blood pressure and body composition in long-term survivors of childhood acute lymphoblastic leukemia. Pediatr Blood Cancer 58:278\u2013282","journal-title":"Pediatr Blood Cancer"},{"key":"5402_CR27","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1097\/MPH.0000000000001349","volume":"41","author":"T Ociepa","year":"2019","unstructured":"Ociepa T, Bartnik M, Zielezi\u0144ska K, Urasi\u0144ski T (2019) Prevalence and risk factors for arterial hypertension development in childhood acute lymphoblastic leukemia survivors. J Pediatr Hematol Oncol 41:175\u2013180","journal-title":"J Pediatr Hematol Oncol"}],"container-title":["Pediatric Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-021-05402-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00467-021-05402-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-021-05402-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,22]],"date-time":"2022-07-22T15:05:48Z","timestamp":1658502348000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00467-021-05402-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,18]]},"references-count":27,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["5402"],"URL":"https:\/\/doi.org\/10.1007\/s00467-021-05402-3","relation":{},"ISSN":["0931-041X","1432-198X"],"issn-type":[{"value":"0931-041X","type":"print"},{"value":"1432-198X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,18]]},"assertion":[{"value":"10 August 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 December 2021","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 December 2021","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 January 2022","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Ethical approval was waived by the local Ethics Committee of Nationwide Children\u2019s Hospital in view of the retrospective nature of the study, and all the procedures being performed were part of the routine care.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}