{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T18:23:04Z","timestamp":1775326984046,"version":"3.50.1"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T00:00:00Z","timestamp":1674777600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T00:00:00Z","timestamp":1674777600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Nephrol"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1007\/s00467-023-05878-1","type":"journal-article","created":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T09:04:08Z","timestamp":1674810248000},"page":"2023-2031","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Incidence, predictors, and short-term outcomes of acute kidney injury in children with diabetic ketoacidosis: a systematic review"],"prefix":"10.1007","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5230-4730","authenticated-orcid":false,"given":"Jitendra","family":"Meena","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaivinder","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jogender","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lesa","family":"Dawman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karalanglin","family":"Tiewosh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aliza","family":"Mittal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rakesh","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Devi","family":"Dayal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,1,27]]},"reference":[{"key":"5878_CR1","doi-asserted-by":"publisher","unstructured":"Rabbone I, Maltoni G, Tinti D, Zucchini S, Cherubini V, Bonfanti R, Scaramuzza A\u00a0(2020) Diabetes Study Group of the Italian Society for Pediatric Endocrinology and Diabetology (ISPED). Arch Dis Child 105:363\u2013366. https:\/\/doi.org\/10.1136\/archdischild-2019-316903","DOI":"10.1136\/archdischild-2019-316903"},{"key":"5878_CR2","doi-asserted-by":"publisher","unstructured":"Katsarou A, Gudbj\u00f6rnsdottir S, Rawshani A, Dabelea D, Bonifacio E, Anderson BJ, Jacobsen LM, Schatz DA, Lernmark \u00c5\u00a0(2017) Type 1 diabetes mellitus. Nat Rev Dis Primers 3:17016. https:\/\/doi.org\/10.1038\/nrdp.2017.16","DOI":"10.1038\/nrdp.2017.16"},{"key":"5878_CR3","doi-asserted-by":"publisher","first-page":"201","DOI":"10.2147\/IJNRD.S115096","volume":"9","author":"R Gordillo","year":"2016","unstructured":"Gordillo R, Ahluwalia T, Woroniecki R (2016) Hyperglycemia and acute kidney injury in critically ill children. Int J Nephrol Renovasc Dis 9:201\u2013204. https:\/\/doi.org\/10.2147\/IJNRD.S115096","journal-title":"Int J Nephrol Renovasc Dis"},{"key":"5878_CR4","doi-asserted-by":"publisher","unstructured":"Hessey E, Melhem N, Alobaidi R, Ulrich E, Morgan C, Bagshaw SM, Sinha MD (2021) Acute kidney injury in critically ill children is not all acute: lessons over the last 5 years. Front Pediatr 9:195. https:\/\/doi.org\/10.3389\/fped.2021.648587","DOI":"10.3389\/fped.2021.648587"},{"key":"5878_CR5","doi-asserted-by":"publisher","unstructured":"Huang JX, Casper TC, Pitts C, Myers S, Loomba L, Ramesh J, Kuppermann N, Glaser N (2021) Association of acute kidney injury during diabetic ketoacidosis with risk of microalbuminuria in children with type 1 diabetes. JAMA Pediatr 176:169\u2013175. https:\/\/doi.org\/10.1001\/jamapediatrics.2021.5038","DOI":"10.1001\/jamapediatrics.2021.5038"},{"key":"5878_CR6","doi-asserted-by":"publisher","unstructured":"Piani F, Reinicke T, Borghi C, Tommerdahl KL, Cara-Fuentes G, Johnson RJ, Bjornstad P\u00a0(2021) Acute kidney injury in pediatric diabetic kidney disease. Front Pediatr 9:668033. https:\/\/doi.org\/10.3389\/fped.2021.668033","DOI":"10.3389\/fped.2021.668033"},{"key":"5878_CR7","doi-asserted-by":"publisher","unstructured":"Huang SK, Huang CY, Lin CH, Cheng BW, Chiang YT, Lee YC, Yeh SN, Chan CI, Chua WK, Lee YJ, Ting WH (2020) Acute kidney injury is a common complication in children and adolescents hospitalized for diabetic ketoacidosis. PLoS One 15:e0239160. https:\/\/doi.org\/10.1371\/journal.pone.0239160","DOI":"10.1371\/journal.pone.0239160"},{"key":"5878_CR8","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1007\/s13312-018-1274-8","volume":"55","author":"M Baalaaji","year":"2018","unstructured":"Baalaaji M, Jayashree M, Nallasamy K, Singhi S, Bansal A (2018) Predictors and outcome of acute kidney injury in children with diabetic ketoacidosis. Indian Pediatr 55:311\u2013314","journal-title":"Indian Pediatr"},{"key":"5878_CR9","doi-asserted-by":"publisher","first-page":"e170020","DOI":"10.1001\/jamapediatrics.2017.0020","volume":"171","author":"BE Hursh","year":"2017","unstructured":"Hursh BE, Ronsley R, Islam N, Mammen C, Panagiotopoulos C (2017) Acute kidney injury in children with type 1 diabetes hospitalized for diabetic ketoacidosis. JAMA Pediatr 171:e170020. https:\/\/doi.org\/10.1001\/jamapediatrics.2017.0020","journal-title":"JAMA Pediatr"},{"key":"5878_CR10","doi-asserted-by":"publisher","first-page":"e10","DOI":"10.1097\/PCC.0000000000001758","volume":"20","author":"A Weissbach","year":"2019","unstructured":"Weissbach A, Zur N, Kaplan E, Kadmon G, Gendler Y, Nahum E (2019) Acute kidney injury in critically ill children admitted to the picu for diabetic ketoacidosis. A retrospective study. Pediatr Crit Care Med 20:e10\u2013e14. https:\/\/doi.org\/10.1097\/PCC.0000000000001758","journal-title":"Pediatr Crit Care Med"},{"key":"5878_CR11","doi-asserted-by":"publisher","unstructured":"Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff\nJM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hr\u00f3bjartsson A, Lalu MM, Li T, Loder EW, Mayo-\nWilson E, McDonald S, McGuinness LA, Stewart LA, Thomas J, Tricco AC, Welch VA, Whiting P, Moher D (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. PLoS Med 18:e1003583. https:\/\/doi.org\/10.1371\/journal.pmed.1003583","DOI":"10.1371\/journal.pmed.1003583"},{"key":"5878_CR12","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.jclinepi.2016.01.021","volume":"75","author":"J McGowan","year":"2016","unstructured":"McGowan J, Sampson M, Salzwedel DM, Cogo E, Foerster V, Lefebvre C (2016) PRESS Peer Review of Electronic Search Strategies: 2015 Guideline Statement. J Clin Epidemiol 75:40\u201346. https:\/\/doi.org\/10.1016\/j.jclinepi.2016.01.021","journal-title":"J Clin Epidemiol"},{"key":"5878_CR13","unstructured":"Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group (2012) KDIGO clinical practice guideline for acute kidney injury. Kidney Int Suppl 2:1\u2013138.\u00a0https:\/\/kdigo.org\/guidelines\/acute-kidney-injury\/.\u00a0Accessed\u00a013 Aug 2022"},{"key":"5878_CR14","doi-asserted-by":"publisher","first-page":"1028","DOI":"10.1038\/sj.ki.5002231","volume":"71","author":"A Akcan-Arikan","year":"2007","unstructured":"Akcan-Arikan A, Zappitelli M, Loftis LL, Washburn KK, Jefferson LS, Goldstein SL (2007) Modified RIFLE criteria in critically ill children with acute kidney injury. Kidney Int 71:1028\u20131035. https:\/\/doi.org\/10.1038\/sj.ki.5002231","journal-title":"Kidney Int"},{"key":"5878_CR15","unstructured":"National Heart, Lung, and Blood Institute (2021) Study quality assessment tools. https:\/\/www.nhlbi.nih.gov\/health-topics\/study-quality-assessment-tools. Accessed 8 Jan 2022"},{"key":"5878_CR16","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1097\/XEB.0000000000000141","volume":"16","author":"L Furuya-Kanamori","year":"2018","unstructured":"Furuya-Kanamori L, Barendregt JJ, Doi SAR (2018) A new improved graphical and quantitative method for detecting bias in meta-analysis. Int J Evid Based Healthc 16:195\u2013203. https:\/\/doi.org\/10.1097\/XEB.0000000000000141","journal-title":"Int J Evid Based Healthc"},{"key":"5878_CR17","doi-asserted-by":"publisher","first-page":"135","DOI":"10.5546\/aap.2020.eng.135","volume":"118","author":"C S\u00e1nchez Garc\u00eda","year":"2020","unstructured":"S\u00e1nchez Garc\u00eda C, Briones Castellanos M, Velasco Morales A (2020) Acute kidney injury and diabetic ketoacidosis in pediatric patients: risk factors. Arch Argent Pediatr 118:135\u2013138. https:\/\/doi.org\/10.5546\/aap.2020.eng.135","journal-title":"Arch Argent Pediatr"},{"key":"5878_CR18","doi-asserted-by":"publisher","first-page":"e2720","DOI":"10.1210\/clinem\/dgab090","volume":"106","author":"P Marzuillo","year":"2021","unstructured":"Marzuillo P, Iafusco D, Zanfardino A, Guarino S et al (2021) Acute kidney injury and renal tubular damage in children with type 1 diabetes mellitus onset. J Clin Endocrinol Metab 106:e2720\u2013e2737. https:\/\/doi.org\/10.1210\/clinem\/dgab090","journal-title":"J Clin Endocrinol Metab"},{"key":"5878_CR19","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1007\/s12098-020-03549-9","volume":"88","author":"EM Yang","year":"2021","unstructured":"Yang EM, Lee HG, Oh KY, Kim CJ (2021) Acute kidney injury in pediatric diabetic ketoacidosis. Indian J Pediatr 88:568\u2013573. https:\/\/doi.org\/10.1007\/s12098-020-03549-9","journal-title":"Indian J Pediatr"},{"key":"5878_CR20","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1515\/jpem-2020-0251","volume":"34","author":"PP Giri","year":"2021","unstructured":"Giri PP, Akhtar S, Laha S, Sinha R (2021) Are we ignoring coexisting rhabdomyolysis as an important aggravating factor for acute kidney injury among childhood diabetic ketoacidosis? J Pediatr Endocrinol Metab 34:251\u2013254. https:\/\/doi.org\/10.1515\/jpem-2020-0251","journal-title":"J Pediatr Endocrinol Metab"},{"key":"5878_CR21","doi-asserted-by":"publisher","first-page":"e2025481","DOI":"10.1001\/jamanetworkopen.2020.25481","volume":"3","author":"SR Myers","year":"2020","unstructured":"Myers SR, Glaser NS, Trainor JL, Nigrovic LE, Garro A, Tzimenatos L, Quayle KS, Kwok MY, Rewers A, Stoner MJ, Schunk JE, McManemy JK, Brown KM, DePiero AD, Olsen CS, Casper TC, Ghetti S, Kuppermann N, Pediatric Emergency Care Applied Research Network (PECARN) DKA FLUID Study Group (2020) Frequency and risk factors of acute kidney injury during diabetic ketoacidosis in children and association with neurocognitive outcomes. JAMA Netw Open 3:e2025481. https:\/\/doi.org\/10.1001\/jamanetworkopen.2020.25481","journal-title":"JAMA Netw Open"},{"key":"5878_CR22","doi-asserted-by":"publisher","first-page":"A232","DOI":"10.1136\/archdischild-2019-rcpch.556","volume":"104","author":"CH Ho","year":"2019","unstructured":"Ho CH, Wong CW, Randell TR (2019) G575(P) Acute kidney injury and diabetic ketoacidosis; intravenous fluids or ph the culprit? Arch Dis Child 104:A232. https:\/\/doi.org\/10.1136\/archdischild-2019-rcpch.556","journal-title":"Arch Dis Child"},{"key":"5878_CR23","doi-asserted-by":"publisher","unstructured":"Bhowmick R, Krishnan G, R R (2021) O030 \/ #804: Outcome of acute kidney injury in pediatric diabetic ketoacidosis: one-year prospective cohort study. Pediatr Crit Care Med 22 (Supplement 1 3S):19. https:\/\/doi.org\/10.1097\/01.pcc.0000738224.95557.89","DOI":"10.1097\/01.pcc.0000738224.95557.89"},{"key":"5878_CR24","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1097\/01.pcc.0000738924.08076.f7","volume":"22","author":"S Gupta","year":"2021","unstructured":"Gupta S, Mishra V, Jaswal R, Sharma M (2021) P0145 \/ #1860: risk factors and outcomes of acute kidney injury in children with diabetic ketoacidosis in pediatric intensive care unit at a tertiary care center. Pediatr Crit Care Med 22:99\u2013100. https:\/\/doi.org\/10.1097\/01.pcc.0000738924.08076.f7","journal-title":"Pediatr Crit Care Med"},{"key":"5878_CR25","doi-asserted-by":"publisher","first-page":"1446","DOI":"10.5005\/jp-journals-10071-24038","volume":"25","author":"V Raghunathan","year":"2021","unstructured":"Raghunathan V, Jevalikar G, Dhaliwal M, Singh D et al (2021) Risk factors for cerebral edema and acute kidney injury in children with diabetic ketoacidosis. Indian J Crit Care Med 25:1446\u20131451. https:\/\/doi.org\/10.5005\/jp-journals-10071-24038","journal-title":"Indian J Crit Care Med"},{"key":"5878_CR26","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1186\/s40842-021-00133-8","volume":"7","author":"V Williams","year":"2021","unstructured":"Williams V, Jayashree M, Nallasamy K, Dayal D et al (2021) Serial urinary neutrophil gelatinase associated lipocalin in pediatric diabetic ketoacidosis with acute kidney injury. Clin Diabetes Endocrinol 7:20. https:\/\/doi.org\/10.1186\/s40842-021-00133-8","journal-title":"Clin Diabetes Endocrinol"},{"key":"5878_CR27","doi-asserted-by":"publisher","first-page":"106","DOI":"10.12669\/pjms.341.13875","volume":"34","author":"Q Abbas","year":"2018","unstructured":"Abbas Q, Arbab S, Haque AU, Humayun KN (2018) Spectrum of complications of severe DKA in children in pediatric intensive care unit. Pak J Med Sci 34:106\u2013109. https:\/\/doi.org\/10.12669\/pjms.341.13875","journal-title":"Pak J Med Sci"},{"key":"5878_CR28","doi-asserted-by":"publisher","first-page":"1407","DOI":"10.1007\/s00467-021-05279-2","volume":"37","author":"HM Ahmed","year":"2021","unstructured":"Ahmed HM, Elnaby HRH, Kareem RMAE, Hodeib M (2021) The relationship between hyperchloremia and acute kidney injury in pediatric diabetic ketoacidosis and its impact on clinical outcomes. Pediatr Nephrol 37:1407\u20131413. https:\/\/doi.org\/10.1007\/s00467-021-05279-2","journal-title":"Pediatr Nephrol"},{"key":"5878_CR29","doi-asserted-by":"publisher","unstructured":"Pittman F, Di Somma H, Wong W, Prestidge C, Reed P, Gunn AJ, Jefferies C (2022) Determinants of acute kidney injury in children with new onset type 1 diabetes: a cohort study of children aged <15\u2009years: Auckland, New Zealand (2006-2016). Endocrinol Diabetes Metab 5:e362. https:\/\/doi.org\/10.1002\/edm2.362","DOI":"10.1002\/edm2.362"},{"key":"5878_CR30","doi-asserted-by":"publisher","unstructured":"Yuan XW, Wang X, Tang N, Xie H, Gu W\u00a0(2022) A clinical study of acute kidney injury in children with type 1 diabetes and diabetic ketoacidosis. Zhongguo Dang Dai Er Ke Za Zhi 24:858\u2013862. https:\/\/doi.org\/10.7499\/j.issn.1008-8830.2203123","DOI":"10.7499\/j.issn.1008-8830.2203123"},{"key":"5878_CR31","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1111\/pedi.13370","volume":"23","author":"AM Hegab","year":"2022","unstructured":"Hegab AM, Khalil FF, Abosedera MM (2022) Incidence and factors associated with acute kidney injury among children with type 1 diabetes hospitalized with diabetic ketoacidosis: a prospective study. Pediatr Diabetes 23:783\u2013791. https:\/\/doi.org\/10.1111\/pedi.13370","journal-title":"Pediatr Diabetes"},{"key":"5878_CR32","doi-asserted-by":"publisher","unstructured":"Al Khalifah R, Al-Eyadhy A, Musibeeh N, Alshalawi A, Alanazi N, Alhboob A, Hassan G, Temsah MH, Alhaboob AAN, Raina R, Alhasan K (2022) Risk factors, outcomes, and predictors of resolution of acute kidney injury in children with diabetic ketoacidosis. Pediatr Nephrol 38:573\u2013582. https:\/\/doi.org\/10.1007\/s00467-022-05578-2","DOI":"10.1007\/s00467-022-05578-2"},{"key":"5878_CR33","doi-asserted-by":"publisher","unstructured":"Orban JC, Maizi\u00e8re EM, Ghaddab A, Van Obberghen E, Ichai C (2014) Incidence and characteristics of acute kidney injury in severe diabetic ketoacidosis. PLoS One 9:e110925. https:\/\/doi.org\/10.1371\/journal.pone.0110925","DOI":"10.1371\/journal.pone.0110925"},{"key":"5878_CR34","doi-asserted-by":"publisher","unstructured":"Chen J, Zeng H, Ouyang X, Zhu M, Huang Q, Yu W, Ling L, Lan HY, Xu A, Tang Y (2020) The incidence, risk factors, and long-term outcomes of acute kidney injury in hospitalized diabetic ketoacidosis patients. BMC Nephrol 21:48. https:\/\/doi.org\/10.1186\/s12882-020-1709-z","DOI":"10.1186\/s12882-020-1709-z"},{"key":"5878_CR35","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1111\/j.1523-1755.2004.761_3.x","volume":"66","author":"JJ Friedewald","year":"2004","unstructured":"Friedewald JJ, Rabb H (2004) Inflammatory cells in ischemic acute renal failure. Kidney Int 66:486\u2013491. https:\/\/doi.org\/10.1111\/j.1523-1755.2004.761_3.x","journal-title":"Kidney Int"}],"container-title":["Pediatric Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-023-05878-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00467-023-05878-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-023-05878-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,10]],"date-time":"2023-07-10T09:13:20Z","timestamp":1688980400000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00467-023-05878-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,27]]},"references-count":35,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["5878"],"URL":"https:\/\/doi.org\/10.1007\/s00467-023-05878-1","relation":{},"ISSN":["0931-041X","1432-198X"],"issn-type":[{"value":"0931-041X","type":"print"},{"value":"1432-198X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,27]]},"assertion":[{"value":"9 October 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 December 2022","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 December 2022","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 January 2023","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}