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Written informed consent was obtained from either the parents or patients.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"The Research Foundation Flanders (F.W.O.) supports Pieter Schellekens. DM reports research grants from Otsuka and serves in advisory boards for Otsuka, Sanofi Genzyme and Reata, all outside the submitted work and all paid to her institutions UZ Leuven and KU Leuven, Belgium. The other authors have no conflict of interest to declare related to this manuscript.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}