{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T22:56:24Z","timestamp":1772578584697,"version":"3.50.1"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2023,12,2]],"date-time":"2023-12-02T00:00:00Z","timestamp":1701475200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,12,2]],"date-time":"2023-12-02T00:00:00Z","timestamp":1701475200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Nephrol"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1007\/s00467-023-06231-2","type":"journal-article","created":{"date-parts":[[2023,12,2]],"date-time":"2023-12-02T03:02:05Z","timestamp":1701486125000},"page":"1435-1446","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Complement gene mutations in children with C3 glomerulopathy: do they affect the response to mycophenolate mofetil?"],"prefix":"10.1007","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0995-8501","authenticated-orcid":false,"given":"Neslihan","family":"G\u00fcnay","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0191-4344","authenticated-orcid":false,"given":"\u0130smail","family":"Dursun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6896-5162","authenticated-orcid":false,"given":"\u0130brahim","family":"G\u00f6k\u00e7e","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0790-323X","authenticated-orcid":false,"given":"Mehtap","family":"Akbal\u0131k Kara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7013-1354","authenticated-orcid":false,"given":"Demet","family":"Tekcan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5859-4177","authenticated-orcid":false,"given":"Neslihan","family":"\u00c7i\u00e7ek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3760-7028","authenticated-orcid":false,"given":"Meral","family":"Torun Bayram","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6707-1001","authenticated-orcid":false,"given":"Mustafa","family":"Koyun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1179-8519","authenticated-orcid":false,"given":"Nida","family":"Din\u00e7el","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8817-494X","authenticated-orcid":false,"given":"Hasan","family":"Dursun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2424-6959","authenticated-orcid":false,"given":"Seha","family":"Sayg\u0131l\u0131","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2891-2231","authenticated-orcid":false,"given":"Zeynep Nagehan","family":"Y\u00fcr\u00fck Y\u0131ld\u0131r\u0131m","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9415-1640","authenticated-orcid":false,"given":"Sel\u00e7uk","family":"Y\u00fcksel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5284-5238","authenticated-orcid":false,"given":"Osman","family":"D\u00f6nmez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8946-0481","authenticated-orcid":false,"given":"Sibel","family":"Yel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beltinge","family":"Demircio\u011flu K\u0131l\u0131\u00e7","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3117-5968","authenticated-orcid":false,"given":"\u00d6zlem","family":"Aydo\u011f","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1133-4845","authenticated-orcid":false,"given":"Bahriye","family":"Atm\u0131\u015f","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0774-4419","authenticated-orcid":false,"given":"Aysun","family":"\u00c7alt\u0131k Y\u0131lmaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6530-9672","authenticated-orcid":false,"given":"Sevcan A.","family":"Bakkalo\u011flu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2561-9593","authenticated-orcid":false,"given":"Mehmet Baha","family":"Ayta\u00e7","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5579-6339","authenticated-orcid":false,"given":"Mehmet","family":"Ta\u015fdemir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5456-3509","authenticated-orcid":false,"given":"Belde","family":"Kasap Demir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5901-7398","authenticated-orcid":false,"given":"Alper","family":"Soylu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2359-1961","authenticated-orcid":false,"given":"Elif","family":"\u00c7omak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4630-4790","authenticated-orcid":false,"given":"Asl\u0131","family":"Kantar \u00d6z\u015fahin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7577-5386","authenticated-orcid":false,"given":"Alper","family":"Ka\u00e7ar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3420-9756","authenticated-orcid":false,"given":"Nur","family":"Canpolat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1743-1491","authenticated-orcid":false,"given":"Alev","family":"Y\u0131lmaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2617-4466","authenticated-orcid":false,"given":"\u0130lknur","family":"Giri\u015fgen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kadirye Bet\u00fcl","family":"Akkoyunlu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0850-1964","authenticated-orcid":false,"given":"Harika","family":"Alpay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5142-8432","authenticated-orcid":false,"given":"Hakan M.","family":"Poyrazo\u011flu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,12,2]]},"reference":[{"key":"6231_CR1","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1159\/000507254","volume":"144","author":"F Caravaca-Font\u00e1n","year":"2020","unstructured":"Caravaca-Font\u00e1n F, Lucientes L, Cavero T, Praga M (2020) Update on C3 glomerulopathy: a complement-mediated disease. Nephron 144:272\u2013280","journal-title":"Nephron"},{"key":"6231_CR2","doi-asserted-by":"publisher","first-page":"46","DOI":"10.2215\/CJN.04700513","volume":"9","author":"NR Medjeral-Thomas","year":"2014","unstructured":"Medjeral-Thomas NR, O\u2019Shaughnessy MM, O\u2019Regan JA, Traynor C, Flanagan M, Wong L, Teoh CW, Awan A, Waldron M, Cairns T, O\u2019Kelly P, Dorman AM, Pickering MC, Conlon PJ, Cook HT (2014) C3 glomerulopathy: clinicopathologic features and predictors of outcome. Clin J Am Soc Nephrol 9:46\u201353","journal-title":"Clin J Am Soc Nephrol"},{"key":"6231_CR3","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1093\/oxfordjournals.ndt.a027821","volume":"13","author":"R Coppo","year":"1998","unstructured":"Coppo R, Gianoglio B, Porcellini MG, Maringhini S (1998) Frequency of renal diseases and clinical indications for renal biopsy in children (report of the Italian National Registry of Renal Biopsies in Children). Group of Renal Immunopathology of the Italian Society of Pediatric Nephrology and Group of Renal Immunopathology of the Italian Society of Nephrology. Nephrol Dial Transplant 13:293\u2013297","journal-title":"Nephrol Dial Transplant"},{"key":"6231_CR4","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1038\/ki.2013.377","volume":"84","author":"MC Pickering","year":"2013","unstructured":"Pickering MC, D\u2019agati VD, Nester CM, Smith RJ, Haas M, Appel GB, Alpers CE, Bajema IM, Bedrosian C, Braun M, Doyle M, Fakhouri F, Fervenza FC, Fogo AB, Fremeaux-Bacchi V, Gale DP, Jorge EG, Harris CL, Holers VM, Johnson S, Lavin PJ, Medjeral-Thomas N, Morgan BP, Nast CC, Noel L, Peters DK, Cordoba SR, Servais A, Sethi S, Song WC, Tamburini P, Thurman JM, Zavros M, Cook HT (2013) C3 glomerulopathy: consensus report. Kidney Int 84:1079\u20131089","journal-title":"Kidney Int"},{"key":"6231_CR5","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1016\/j.kint.2017.10.022","volume":"93","author":"AS Bomback","year":"2018","unstructured":"Bomback AS, Santoriello D, Avasare RS, Regunathan-Shenk R, Canetta PA, Ahn W, Radhakrishnan J, Marasa M, Rosenstiel PE, Herlitz LC, Markowitz GS, D\u2019Agati VD, Appel GB (2018) C3 glomerulonephritis and dense deposit disease share a similar disease course in a large United States cohort of patients with C3 glomerulopathy. Kidney Int 93:977\u2013985","journal-title":"Kidney Int"},{"key":"6231_CR6","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1038\/ki.2012.63","volume":"82","author":"A Servais","year":"2012","unstructured":"Servais A, No\u00ebl LH, Roumenina LT, Le Quintrec M, Ngo S, Dragon-Durey MA, Macher MA, Zuber J, Karras A, Provot F, Moulin B, Gr\u00fcnfeld JP, Niaudet P, Lesavre P, Fr\u00e9meaux-Bacchi V (2012) Acquired and genetic complement abnormalities play a critical role in dense deposit disease and other C3 glomerulopathies. Kidney Int 82:454\u2013464","journal-title":"Kidney Int"},{"key":"6231_CR7","doi-asserted-by":"publisher","first-page":"1639","DOI":"10.2215\/CJN.00320121","volume":"16","author":"EKS Wong","year":"2021","unstructured":"Wong EKS, Marchbank KJ, Lomax-Browne H, Pappworth IY, Denton H, Cooke K, Ward S, McLoughlin AC, Richardson G, Wilson V, Harris CL, Morgan BP, Hakobyan S, McAlinden P, Gale DP, Maxwell H, Christian M, Malcomson R, Goodship THJ, Marks SD, Pickering MC, Kavanagh D, Cook HT, Johnson SA, MPGN\/DDD\/C3 Glomerulopathy Rare Disease Group and National Study of MPGN\/DDD\/C3 Glomerulopathy Investigators (2021) C3 glomerulopathy and related disorders in children: etiology-phenotype correlation and outcomes. Clin J Am Soc Nephrol 16:1639\u20131651","journal-title":"Clin J Am Soc Nephrol"},{"key":"6231_CR8","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1007\/978-3-030-52719-8_29","volume-title":"Pediatric Nephrology","author":"C Licht","year":"2022","unstructured":"Licht C, Vivarelli M, Riedl Khursigara M, Pickering MC, Walker PD (2022) Membranoproliferative glomerulonephritis and C3 glomerulopathy in children. In: Emma F, Goldstein SL, Bagga A, Bates CM, Shroff R (eds) Pediatric Nephrology, 8th edn. Springer, Cham, pp 563\u2013593","edition":"8"},{"key":"6231_CR9","doi-asserted-by":"publisher","first-page":"2313","DOI":"10.1016\/j.ekir.2020.09.019","volume":"5","author":"A Kirpalani","year":"2020","unstructured":"Kirpalani A, Jawa N, Smoyer WE, Licht C, Midwest Pediatric Nephrology Consortium (2020) Long-term outcomes of C3 glomerulopathy and immune-complex membranoproliferative glomerulonephritis in children. Kidney Int Rep 5:2313\u20132324","journal-title":"Kidney Int Rep"},{"key":"6231_CR10","doi-asserted-by":"publisher","first-page":"1195","DOI":"10.1007\/s00467-020-04799-7","volume":"36","author":"AS P\u0131narba\u015f\u0131","year":"2021","unstructured":"P\u0131narba\u015f\u0131 AS, Dursun I, Gokce I, \u00c7omak E, Sayg\u0131l\u0131 S, Bayram MT, Donmez O, Melek E, Tekcan D, \u00c7i\u00e7ek N, Y\u0131lmaz D, Tabel Y, Y\u0131ld\u0131r\u0131m ZY, Bahat E, Koyun M, Soylu A, Canpolat N, Aksu B, \u00c7elak\u0131l ME, Ta\u015fdemir M, Benzer M, \u00d6z\u00e7elik G, Bakkalo\u011flu SA, D\u00fc\u015f\u00fcnsel R (2021) Predictors of poor kidney outcome in children with C3 glomerulopathy. Pediatr Nephrol 36:1195\u20131205","journal-title":"Pediatr Nephrol"},{"key":"6231_CR11","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.molimm.2016.01.010","volume":"71","author":"P Iatropoulos","year":"2016","unstructured":"Iatropoulos P, Noris M, Mele C, Piras R, Valoti E, Bresin E, Curreri M, Mondo E, Zito A, Gamba S, Bettoni S, Murer L, Fremeaux-Bacchi V, Vivarelli M, Emma F, Daina E, Remuzzi G (2016) Complement gene variants determine the risk of immunoglobulin-associated MPGN and C3 glomerulopathy and predict long-term renal outcome. Mol Immunol 71:131\u2013142","journal-title":"Mol Immunol"},{"key":"6231_CR12","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1016\/j.mayocp.2018.05.019","volume":"93","author":"A Ravindran","year":"2018","unstructured":"Ravindran A, Fervenza FC, Smith RJH, De Vriese AS, Sethi S (2018) C3 glomerulopathy: ten years\u2019 experience at Mayo Clinic. Mayo Clin Proc 93:991\u20131008","journal-title":"Mayo Clin Proc"},{"key":"6231_CR13","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1007\/s00467-015-3310-4","volume":"32","author":"M Riedl","year":"2017","unstructured":"Riedl M, Thorner P, Licht C (2017) C3 glomerulopathy. Pediatr Nephrol 32:43\u201357","journal-title":"Pediatr Nephrol"},{"key":"6231_CR14","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1016\/j.kint.2021.05.015","volume":"100","author":"BH Rovin","year":"2021","unstructured":"Rovin BH, Adler SG, Barratt J, Bridoux F, Burdge KA, Chan TM, Cook HT, Fervenza FC, Gibson KL, Glassock RJ, Jayne DRW, Jha V, Liew A, Liu ZH, Mej\u00eda-Vilet JM, Nester CM, Radhakrishnan J, Rave E (2021) Executive summary of the KDIGO 2021 Guideline for the Management of Glomerular Diseases. Kidney Int 100:753\u2013779","journal-title":"Kidney Int"},{"key":"6231_CR15","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.1038\/ki.2015.227","volume":"88","author":"C Rabasco","year":"2015","unstructured":"Rabasco C, Cavero T, Rom\u00e1n E, Rojas-Rivera J, Olea T, Espinosa M, Cabello V, Fern\u00e1ndez-Juarez G, Gonz\u00e1lez F, \u00c1vila A, Baltar JM, D\u00edaz M, Alegre R, El\u00edas S, Ant\u00f3n M, Frutos MA, Pobes A, Blasco M, Mart\u00edn F, Bernis C, Mac\u00edas M, Barroso S, de Lorenzo A, Ariceta G, L\u00f3pez-Mendoza M, Rivas B, L\u00f3pez-Revuelta K, Campistol JM, Mendiz\u00e1bal S, de C\u00f3rdoba SR, Praga M, Spanish Group for the Study of Glomerular Diseases (GLOSEN) (2015) Effectiveness of mycophenolate mofetil in C3 glomerulonephritis. Kidney Int 88:1153\u20131160","journal-title":"Kidney Int"},{"key":"6231_CR16","doi-asserted-by":"publisher","first-page":"406","DOI":"10.2215\/CJN.09080817","volume":"13","author":"RS Avasare","year":"2018","unstructured":"Avasare RS, Canetta PA, Bomback AS, Marasa M, Caliskan Y, Ozluk Y, Li Y, Gharavi AG, Appel GB (2018) Mycophenolate mofetil in combination with steroids for treatment of c3 glomerulopathy: a case series. Clin J Am Soc Nephrol 13:406\u2013413","journal-title":"Clin J Am Soc Nephrol"},{"key":"6231_CR17","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.2215\/CJN.15241219","volume":"15","author":"F Caravaca-Font\u00e1n","year":"2020","unstructured":"Caravaca-Font\u00e1n F, D\u00edaz-Encarnaci\u00f3n MM, Lucientes L, Cavero T, Cabello V, Ariceta G, Quintana LF, Marco H, Barros X, Ramos N, Rodr\u00edguez-Mendiola N, Cruz S, Fern\u00e1ndez-Ju\u00e1rez G, Rodr\u00edguez A, P\u00e9rez de Jos\u00e9 A, Rabasco C, Rodado R, Fern\u00e1ndez L, P\u00e9rez G\u00f3mez V, \u00c1vila AI, Bravo L, Lumbreras J, Allende N, Sanchez de la Nieta MD, Rodr\u00edguez E, Olea T, Melgosa M, Huerta A, Miquel R, Mon C, Fraga G, de Lorenzo A, Draibe J, Cano-Meg\u00edas M, Gonz\u00e1lez F, Shabaka A, L\u00f3pez-Rubio ME, Fenollosa M\u00c1, Mart\u00edn-Penagos L, Da Silva I, Alonso Titos J, Rodr\u00edguez de C\u00f3rdoba S, Goicoechea de Jorge E, Praga M, Spanish Group for the Study of Glomerular Diseases GLOSEN (2020) Mycophenolate mofetil in C3 glomerulopathy and pathogenic drivers of the disease. Clin J Am Soc Nephrol 15:1287\u20131298","journal-title":"Clin J Am Soc Nephrol"},{"key":"6231_CR18","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1016\/j.kint.2016.10.005","volume":"91","author":"TH Goodship","year":"2017","unstructured":"Goodship TH, Cook HT, Fakhouri F, Fervenza FC, Fr\u00e9meaux-Bacchi V, Kavanagh D, Nester CM, Noris M, Pickering MC, Rodr\u00edguez de C\u00f3rdoba S, Roumenina LT, Sethi S, Smith RJ, for the Conference Participants (2017) Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a \u201cKidney Disease: improving Global Outcomes\u201d (KDIGO) Controversies Conference. Kidney Int 91:539\u2013551","journal-title":"Kidney Int"},{"key":"6231_CR19","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1038\/gim.2015.30","volume":"17","author":"S Richards","year":"2015","unstructured":"Richards S, Aziz N, Bale S, Bick D, Das S, Gastier-Foster J, Grody WW, Hegde M, Lyon E, Spector E, Voelkerding K, Rehm HL, ACMG Laboratory Quality Assurance Committee (2015) Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology. Genet Med 17:405\u2013424","journal-title":"Genet Med"},{"key":"6231_CR20","doi-asserted-by":"publisher","first-page":"1919","DOI":"10.1093\/ndt\/gfy033","volume":"33","author":"W Zhao","year":"2018","unstructured":"Zhao W, Ding Y, Lu J, Zhang T, Chen D, Zhang H, Zeng C, Liu Z, Chen H (2018) Genetic analysis of the complement pathway in C3 glomerulopathy. Nephrol Dial Transplant 33:1919\u20131927","journal-title":"Nephrol Dial Transplant"},{"key":"6231_CR21","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.kint.2021.05.021","volume":"100","author":"Kidney Disease: Improving Global Outcomes (KDIGO) Glomerular Diseases Work Group","year":"2021","unstructured":"Kidney Disease: Improving Global Outcomes (KDIGO) Glomerular Diseases Work Group (2021) KDIGO 2021 Clinical Practice Guideline for the Management of Glomerular Diseases. Kidney Int 100:1\u2013276","journal-title":"Kidney Int"},{"key":"6231_CR22","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1007\/s00467-021-05088-7","volume":"37","author":"M Vivarelli","year":"2022","unstructured":"Vivarelli M, van de Kar N, Labbadia R, Diomedi-Camassei F, Thurman JM (2022) A clinical approach to children with C3 glomerulopathy. Pediatr Nephrol 37:521\u2013535","journal-title":"Pediatr Nephrol"},{"key":"6231_CR23","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1681\/ASN.2015040385","volume":"27","author":"F Bu","year":"2016","unstructured":"Bu F, Borsa NG, Jones MB, Takanami E, Nishimura C, Hauer JJ, Azaiez H, Black-Ziegelbein EA, Meyer NC, Kolbe DL, Li Y, Frees K, Schnieders MJ, Thomas C, Nester C, Smith RJ (2016) High-throughput genetic testing for thrombotic microangiopathies and C3 glomerulopathies. J Am Soc Nephrol 27:1245\u20131253","journal-title":"J Am Soc Nephrol"},{"key":"6231_CR24","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1038\/s41581-018-0107-2","volume":"15","author":"RJH Smith","year":"2019","unstructured":"Smith RJH, Appel GB, Blom AM, Cook HT, D\u2019Agati VD, Fakhouri F, Fremeaux-Bacchi V, J\u00f3zsi M, Kavanagh D, Lambris JD, Noris M, Pickering MC, Remuzzi G, de C\u00f3rdoba SR, Sethi S, Van der Vlag J, Zipfel PF, Nester CM (2019) C3 glomerulopathy \u2013 understanding a rare complement-driven renal disease. Nat Rev Nephrol 15:129\u2013143","journal-title":"Nat Rev Nephrol"},{"key":"6231_CR25","doi-asserted-by":"publisher","first-page":"79","DOI":"10.4103\/1319-2442.279964","volume":"31","author":"AS Pinarbasi","year":"2020","unstructured":"Pinarbasi AS, Dursun I, Poyrazoglu MH, Akgun H, Bozpolat A, Dusunsel R (2020) Evaluation of the children with C3 glomerulopathy. Saudi J Kidney Dis Transpl 31:79\u201389","journal-title":"Saudi J Kidney Dis Transpl"},{"key":"6231_CR26","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1007\/s00467-020-04768-0","volume":"36","author":"Z Zahir","year":"2021","unstructured":"Zahir Z, Wani AS, Gupta A, Agrawal V (2021) Pediatric C3 glomerulopathy: a 12-year single-center experience. Pediatr Nephrol 36:601\u2013610","journal-title":"Pediatr Nephrol"},{"key":"6231_CR27","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1159\/000479012","volume":"46","author":"Y Caliskan","year":"2017","unstructured":"Caliskan Y, Torun ES, Tiryaki TO, Oruc A, Ozluk Y, Akgul SU, Temurhan S, Oztop N, Kilicaslan I, Sever MS (2017) Immunosuppressive treatment in C3 glomerulopathy: is it really effective? Am J Nephrol 46:96\u2013107","journal-title":"Am J Nephrol"},{"key":"6231_CR28","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1159\/000524552","volume":"2","author":"J Hou","year":"2022","unstructured":"Hou J, Ren KYM, Haas M (2022) C3 glomerulopathy: a review with emphasis on ultrastructural features. Glomerular Dis 2:107\u2013120","journal-title":"Glomerular Dis"},{"key":"6231_CR29","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1681\/ASN.2017030258","volume":"29","author":"P Iatropoulos","year":"2018","unstructured":"Iatropoulos P, Daina E, Curreri M, Piras R, Valoti E, Mele C, Bresin E, Gamba S, Alberti M, Breno M, Perna A, Bettoni S, Sabadini E, Murer L, Vivarelli M, Noris M, Remuzzi G; Registry of Membranoproliferative Glomerulonephritis\/C3 Glomerulopathy; Nastasi (2018) Cluster analysis identifies distinct pathogenetic patterns in C3 glomerulopathies\/immune complex-mediated membranoproliferative GN. J Am Soc Nephrol 29:283\u2013294","journal-title":"J Am Soc Nephrol"},{"key":"6231_CR30","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1111\/nep.13522","volume":"24","author":"N Kojc","year":"2019","unstructured":"Kojc N, Bahovec A, Levart TK (2019) C3 glomerulopathy in children: is there still a place for anti-cellular immunosuppression? Nephrology (Carlton) 24:188\u2013194","journal-title":"Nephrology (Carlton)"}],"container-title":["Pediatric Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-023-06231-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00467-023-06231-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-023-06231-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T06:08:05Z","timestamp":1710482885000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00467-023-06231-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,2]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["6231"],"URL":"https:\/\/doi.org\/10.1007\/s00467-023-06231-2","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-3031121\/v1","asserted-by":"object"}]},"ISSN":["0931-041X","1432-198X"],"issn-type":[{"value":"0931-041X","type":"print"},{"value":"1432-198X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,2]]},"assertion":[{"value":"6 June 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 November 2023","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 November 2023","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 December 2023","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}