{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T23:16:32Z","timestamp":1776986192993,"version":"3.51.4"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T00:00:00Z","timestamp":1712534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T00:00:00Z","timestamp":1712534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Nephrol"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1007\/s00467-024-06362-0","type":"journal-article","created":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T18:02:05Z","timestamp":1712599325000},"page":"2423-2427","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Antineutrophil cytoplasmic antibody in children with nephrotic syndrome treated with levamisole: a cross-sectional cohort study"],"prefix":"10.1007","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4525-092X","authenticated-orcid":false,"given":"Rajiv","family":"Sinha","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subhankar","family":"Sarkar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sushmita","family":"Banerjee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shakil","family":"Akhtar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjukta","family":"Poddar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deblina","family":"Dasgupta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rana","family":"Saha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jayati","family":"Sengupta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mita","family":"Mandal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yincent","family":"Tse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amitava","family":"Pahari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,4,8]]},"reference":[{"key":"6362_CR1","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1016\/j.ajoms.2016.03.004","volume":"28","author":"ML Chandy","year":"2016","unstructured":"Chandy ML, Soman C, Kumar SP, Kurup S, Jose R (2016) Understanding molecular mechanisms in multivariant actions of levamisole as an anti-helminthic, anti-inflammatory, antioxidant, anti-neoplastic and immunomodulatory drug. J Oral Maxillofac Surg Med Pathol 28:354\u2013357. https:\/\/doi.org\/10.1016\/j.ajoms.2016.03.004","journal-title":"J Oral Maxillofac Surg Med Pathol"},{"key":"6362_CR2","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1016\/j.kint.2017.08.011","volume":"93","author":"MP Gruppen","year":"2018","unstructured":"Gruppen MP, Bouts AH, Jansen-van der Weide MC, Merkus MP, Zurowska A, Maternik M, Massella L, Emma F, Niaudet P, Cornelissen EAM, Schurmans T, Raes A, van de Walle J, van Dyck M, Gulati A, Bagga A, Davin JC, Levamisole Study Group (2018) A randomized clinical trial indicates that levamisole increases the time to relapse in children with steroid-sensitive idiopathic nephrotic syndrome. Kidney Int 93:510\u2013518. https:\/\/doi.org\/10.1016\/j.kint.2017.08.011","journal-title":"Kidney Int"},{"key":"6362_CR3","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1016\/j.kint.2018.08.039","volume":"95","author":"A Sinha","year":"2019","unstructured":"Sinha A, Puraswani M, Kalaivani M, Goyal P, Hari P, Bagga A (2019) Efficacy and safety of mycophenolate mofetil versus levamisole in frequently relapsing nephrotic syndrome: an open-label randomized controlled trial. Kidney Int 95:210\u2013218. https:\/\/doi.org\/10.1016\/j.kint.2018.08.039","journal-title":"Kidney Int"},{"key":"6362_CR4","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1007\/s004670050753","volume":"13","author":"G Barbano","year":"1999","unstructured":"Barbano G, Ginevri F, Ghiggeri GM, Gusmano R (1999) Disseminated autoimmune disease during levamisole treatment of nephrotic syndrome. Pediatr Nephrol 13:602\u2013603. https:\/\/doi.org\/10.1007\/s004670050753","journal-title":"Pediatr Nephrol"},{"key":"6362_CR5","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1111\/j.1525-1470.1997.tb00695.x","volume":"14","author":"S Menni","year":"1997","unstructured":"Menni S, Pistritto G, Gianotti R, Ghio L, Edefonti A (1997) Ear lobe bilateral necrosis by levamisole-induced occlusive vasculitis in a pediatric patient. Pediatr Dermatol 14:477\u2013479. https:\/\/doi.org\/10.1111\/j.1525-1470.1997.tb00695.x","journal-title":"Pediatr Dermatol"},{"key":"6362_CR6","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1046\/j.1365-2133.1999.02833.x","volume":"140","author":"F Rongioletti","year":"1999","unstructured":"Rongioletti F, Ghio L, Ginevri F, Bleidl D, Rinaldi S, Edefonti A, Gambini C, Rizzoni G, Rebora A (1999) Purpura of the ears: a distinctive vasculopathy with circulating autoantibodies complicating long-term treatment with levamisole in children. Br J Dermatol 140:948\u2013951. https:\/\/doi.org\/10.1046\/j.1365-2133.1999.02833.x","journal-title":"Br J Dermatol"},{"key":"6362_CR7","doi-asserted-by":"publisher","first-page":"650","DOI":"10.3390\/medicina58050650","volume":"58","author":"S Bernardi","year":"2022","unstructured":"Bernardi S, Innocenti S, Charbit M, Boyer O (2022) Late onset of ANCA vasculitis as a side effect of levamisole treatment in nephrotic syndrome. Medicina (Kaunas) 58:650. https:\/\/doi.org\/10.3390\/medicina58050650","journal-title":"Medicina (Kaunas)"},{"key":"6362_CR8","doi-asserted-by":"publisher","first-page":"1795","DOI":"10.1007\/s00467-020-04915-7","volume":"36","author":"L Krischock","year":"2021","unstructured":"Krischock L, Pannila P, Kennedy SE (2021) Levamisole and ANCA positivity in childhood nephrotic syndrome. Pediatr Nephrol 36:1795\u20131802. https:\/\/doi.org\/10.1007\/s00467-020-04915-7","journal-title":"Pediatr Nephrol"},{"key":"6362_CR9","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1080\/20009666.2018.1536242","volume":"8","author":"Q Jin","year":"2018","unstructured":"Jin Q, Kant S, Alhariri J, Geetha D (2018) Levamisole adulterated cocaine associated ANCA vasculitis: review of literature and update on pathogenesis. J Community Hosp Intern Med Perspect 8:339\u2013344. https:\/\/doi.org\/10.1080\/20009666.2018.1536242","journal-title":"J Community Hosp Intern Med Perspect"},{"key":"6362_CR10","first-page":"975","volume":"38","author":"Indian Pediatric Nephrology Group, Indian Academy of Pediatrics","year":"2001","unstructured":"Indian Pediatric Nephrology Group, Indian Academy of Pediatrics (2001) Consensus statement on management of steroid sensitive nephrotic syndrome. Indian Pediatr 38:975\u2013986","journal-title":"Indian Pediatr"},{"key":"6362_CR11","first-page":"203","volume":"45","author":"A Bagga","year":"2008","unstructured":"Bagga A, Ali U, Banerjee S, Kanitkar M, Phadke KD, Senguttuvan P, Sethi S, Shah M, Indian Pediatric Nephrology Group, Indian Academy of Pediatrics (2008) Management of steroid sensitive nephrotic syndrome: revised guidelines. Indian Pediatr 45:203\u2013214","journal-title":"Indian Pediatr"},{"key":"6362_CR12","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1007\/s13312-021-2217-3","volume":"58","author":"A Sinha","year":"2021","unstructured":"Sinha A, Bagga A, Banerjee S, Mishra K, Mehta A, Agarwal I, Uthup S, Saha A, Mishra OP, Expert Group of Indian Society of Pediatric Nephrology (2021) Steroid sensitive nephrotic syndrome: revised guidelines. Indian Pediatr 58:461\u2013481. https:\/\/doi.org\/10.1007\/s13312-021-2217-3","journal-title":"Indian Pediatr"},{"key":"6362_CR13","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1038\/s41584-018-0145-y","volume":"15","author":"D Nakazawa","year":"2019","unstructured":"Nakazawa D, Masuda S, Tomaru U, Ishizu A (2019) Pathogenesis and therapeutic interventions for ANCA-associated vasculitis. Nat Rev Rheumatol 15:91\u2013101. https:\/\/doi.org\/10.1038\/s41584-018-0145-y","journal-title":"Nat Rev Rheumatol"},{"key":"6362_CR14","first-page":"343","volume":"79","author":"K Chawdhary","year":"2015","unstructured":"Chawdhary K, Parke A (2015) Levamisole-induced vasculitis with renal involvement. Conn Med 79:343\u2013346","journal-title":"Conn Med"},{"key":"6362_CR15","doi-asserted-by":"publisher","first-page":"2799","DOI":"10.2215\/CJN.03440411","volume":"6","author":"MM McGrath","year":"2011","unstructured":"McGrath MM, Isakova T, Rennke HG, Mottola AM, Laliberte KA, Niles JL (2011) Contaminated cocaine and antineutrophil cytoplasmic antibody-associated disease. Clin J Am Soc Nephrol 6:2799\u20132805. https:\/\/doi.org\/10.2215\/CJN.03440411","journal-title":"Clin J Am Soc Nephrol"},{"key":"6362_CR16","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.jbspin.2017.05.022","volume":"85","author":"A N\u00e9el","year":"2018","unstructured":"N\u00e9el A, Agard C, Hamidou M (2018) Vasculitides induced by cocaine and\/or levamisole. Joint Bone Spine 85:9\u201314. https:\/\/doi.org\/10.1016\/j.jbspin.2017.05.022","journal-title":"Joint Bone Spine"},{"key":"6362_CR17","doi-asserted-by":"publisher","first-page":"877","DOI":"10.1007\/s00467-022-05739-3","volume":"38","author":"A Trautmann","year":"2023","unstructured":"Trautmann A, Boyer O, Hodson E, Bagga A, Gipson DS, Samuel S, Wetzels J, Alhasan K, Banerjee S, Bhimma R, Bonilla-Felix M, Cano F, Christian M, Hahn D, Kang HG, Nakanishi K, Safouh H, Trachtman H, Xu H, Cook W, Vivarelli M, Haffner D, International Pediatric Nephrology Association (2023) IPNA clinical practice recommendations for the diagnosis and management of children with steroid-sensitive nephrotic syndrome. Pediatr Nephrol 38:877\u2013919. https:\/\/doi.org\/10.1007\/s00467-022-05739-3","journal-title":"Pediatr Nephrol"}],"container-title":["Pediatric Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-024-06362-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00467-024-06362-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-024-06362-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,25]],"date-time":"2024-06-25T11:08:19Z","timestamp":1719313699000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00467-024-06362-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,8]]},"references-count":17,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["6362"],"URL":"https:\/\/doi.org\/10.1007\/s00467-024-06362-0","relation":{},"ISSN":["0931-041X","1432-198X"],"issn-type":[{"value":"0931-041X","type":"print"},{"value":"1432-198X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,8]]},"assertion":[{"value":"4 February 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 March 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 March 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 April 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}]}}