{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T09:13:59Z","timestamp":1783329239548,"version":"3.54.6"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:00:00Z","timestamp":1773705600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:00:00Z","timestamp":1773705600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100014452","name":"College of Medicine, University of Cincinnati","doi-asserted-by":"publisher","award":["UL1TR001425"],"award-info":[{"award-number":["UL1TR001425"]}],"id":[{"id":"10.13039\/100014452","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Nephrol"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Selective Fetoscopic Laser Photocoagulation (SFLP) is used to treat Twin-Twin Transfusion Syndrome (TTTS), affecting 10\u201315% of monochorionic twin pregnancies. Historical data have reported neonatal acute kidney injury (AKI) as high as 50% following TTTS; however, the incidence of AKI following SFLP remains poorly characterized.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a single-center retrospective study of monochorionic diamniotic twins who underwent SFLP for TTTS between 2010 and 2023. The primary outcome was the development of AKI during the first two weeks of life, defined by the Neonatal Modified KDIGO criteria. Mixed-effects logistic regression was performed to identify associations with AKI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 103 infants included, 15 (14.6%) developed AKI. Twins with AKI were born at earlier gestational age (26\u00a0weeks vs. 30\u00a0weeks,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and had lower birth weights (923 vs. 1320\u00a0g,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01). Adjusted analysis demonstrated longer latency to delivery (OR 0.69, 95% CI 0.54\u20130.88) and greater total number of arteriovenous (AV) anastomoses (OR 0.78, 95% CI 0.64\u20130.94) were associated with decreased odds of AKI.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our postnatal incidence of AKI following SFLP for TTTS is less common than previously described. Our findings suggest that a more extensive AV anastomotic network and\/or longer latency to delivery may allow for improved hemodynamic balance and kidney maturation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00467-026-07232-7","type":"journal-article","created":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T01:10:23Z","timestamp":1773709823000},"page":"2647-2655","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Twin-to-twin transfusion syndrome and neonatal acute kidney injury after selective fetoscopic laser photocoagulation"],"prefix":"10.1007","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2543-1141","authenticated-orcid":false,"given":"Evelyn","family":"Obregon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefanie","family":"Riddle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liu","family":"Chunyan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shelley","family":"Ehrlich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Braxton","family":"Forde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meredith P.","family":"Schuh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart L.","family":"Goldstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cara L.","family":"Slagle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,17]]},"reference":[{"key":"7232_CR1","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1515\/jpm.2010.147","volume":"39","author":"A Baschat","year":"2011","unstructured":"Baschat A, Chmait RH, Deprest J, Gratacos E, Hecher K, WAPM Consensus Group on Twin-to-Twin Transfusion et al (2011) Twin-to-twin transfusion syndrome (TTTS). 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This has since been replaced with the correct version.","order":8,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"CLS is a consultant for Bioporto Diagnostics and Mozarc Medical. No additional conflict of interest to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The NIH had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; or decision to submit the manuscript for publication.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Role of funder\/sponsor (if any)"}}]}}