{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T18:31:51Z","timestamp":1793125911246,"version":"4.5.0"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:00:00Z","timestamp":1777420800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:00:00Z","timestamp":1777420800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Nephrol"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1007\/s00467-026-07308-4","type":"journal-article","created":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T01:13:12Z","timestamp":1777425192000},"page":"3465-3476","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Fluid accumulation and outcomes in children receiving continuous kidney replacement therapy: an appraisal of the WE-ROCK registry"],"prefix":"10.1007","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0358-0760","authenticated-orcid":false,"given":"David T.","family":"Selewski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja M.","family":"Gist","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akash","family":"Deep","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lama","family":"Elbahlawan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana Y.","family":"Fuhrman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben","family":"Gelbart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen M.","family":"Gorga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth E.","family":"Mah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas J.","family":"Ollberding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Reynaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jangdong","family":"Seo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle E.","family":"Soranno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalja L.","family":"Stanski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle C.","family":"Starr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda M.","family":"Uber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Askenazi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott M.","family":"Sutherland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shina","family":"Menon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease (WE-ROCK) Collaborative","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Ahern","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayse Akcan","family":"Arikan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Issa","family":"Alhamoud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rashid","family":"Alobaidi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Anton-Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanthi S","family":"Balani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Barhight","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abby","family":"Basalely","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amee M","family":"Bigelow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriella","family":"Bottari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Cappoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhishek","family":"Chakraborty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eileen A","family":"Ciccia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michaela","family":"Collins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise","family":"Colosimo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerard","family":"Cortina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihaela A","family":"Damian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"De la Mata Navazo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabrielle","family":"DeAbreu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akash","family":"Deep","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathy L","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristin J","family":"Dolan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lama","family":"Elbahlawan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah N","family":"Fernandez Lafever","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana Y","family":"Fuhrman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben","family":"Gelbart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja M","family":"Gist","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen M","family":"Gorga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Guzzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella","family":"Guzzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taiki","family":"Haga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Harvey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise C","family":"Hasson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taylor","family":"Hill-Horowitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haleigh","family":"Inthavong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Joseph","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad","family":"Kaddourah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aadil","family":"Kakajiwala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron D","family":"Kessel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Korn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelli A","family":"Krallman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David M","family":"Kwiatkowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasmine","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurance","family":"Lequier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina Madani","family":"Kia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth E","family":"Mah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleonora","family":"Marinari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan D","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shina","family":"Menon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tahagod H","family":"Mohamed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Morgan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresa A","family":"Mottes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa A","family":"Muff-Luett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siva","family":"Namachivayam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tara M","family":"Neumayr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Nhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abigail","family":"O\u2019Rourke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas J","family":"Ollberding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew G","family":"Pinto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dua","family":"Qutob","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeria","family":"Raggi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Reynaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaccaria","family":"Ricci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zachary A","family":"Rumlow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda J","family":"Santiago Lozano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"See","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David T","family":"Selewski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmela","family":"Serpe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyssa","family":"Serratore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ananya","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiwen V","family":"Shih","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H Stella","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cara L","family":"Slagle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia","family":"Solomon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle E","family":"Soranno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachana","family":"Srivastava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalja L","family":"Stanski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle C","family":"Starr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin K","family":"Stenson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy E","family":"Strong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan A","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sameer V","family":"Thadani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda M","family":"Uber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brynna","family":"Van Wyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tennille N","family":"Webb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huaiyu","family":"Zang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily E","family":"Zangla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Zappitelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,29]]},"reference":[{"key":"7308_CR1","doi-asserted-by":"crossref","unstructured":"Selewski DT, Barhight MF, Bjornstad EC, Ricci Z, de Sousa Tavares M, Akcan-Arikan A, Goldstein SL, Basu R, Bagshaw SM, the Pediatric Acute Disease Quality Initiative Consensus Committee Members (2024) Fluid assessment, fluid balance, and fluid overload in sick children: a report from the Pediatric Acute Disease Quality Initiative (ADQI) conference. Pediatr Nephrol 39:955\u2013979","DOI":"10.1007\/s00467-023-06156-w"},{"key":"7308_CR2","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1007\/s00467-019-04468-4","volume":"35","author":"SM Gorga","year":"2020","unstructured":"Gorga SM, Sahay RD, Askenazi DJ, Bridges BC, Cooper DS, Paden ML, Zappitelli M, Gist KM, Gien J, Basu RK, Jetton JG, Murphy HJ, King E, Fleming GM, Selewski DT (2020) Fluid overload and fluid removal in pediatric patients on extracorporeal membrane oxygenation requiring continuous renal replacement therapy: a multicenter retrospective cohort study. Pediatr Nephrol 35:871\u2013882","journal-title":"Pediatr Nephrol"},{"key":"7308_CR3","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1053\/j.ajkd.2009.10.048","volume":"55","author":"SM Sutherland","year":"2010","unstructured":"Sutherland SM, Zappitelli M, Alexander SR, Chua AN, Brophy PD, Bunchman TE, Hackbarth R, Somers MJ, Baum M, Symons JM, Flores FX, Benfield M, Askenazi D, Chand D, Fortenberry JD, Mahan JD, McBryde K, Blowey D, Goldstein SL (2010) Fluid overload and mortality in children receiving continuous renal replacement therapy: the prospective pediatric continuous renal replacement therapy registry. Am J Kidney Dis 55:316\u2013325","journal-title":"Am J Kidney Dis"},{"key":"7308_CR4","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1097\/CCM.0000000000005791","volume":"51","author":"DT Selewski","year":"2023","unstructured":"Selewski DT, Gist KM, Basu RK, Goldstein SL, Zappitelli M, Soranno DE, Mammen C, Sutherland SM, Askenazi DJ, Ricci Z, Akcan-Arikan A, Gorga SM, Gillespie SE, Woroniecki R (2023) Impact of the magnitude and timing of fluid overload on outcomes in critically ill children: a report from the Multicenter International Assessment of Worldwide Acute Kidney Injury, Renal Angina, and Epidemiology (AWARE) Study. Crit Care Med 51:606\u2013618","journal-title":"Crit Care Med"},{"key":"7308_CR5","doi-asserted-by":"publisher","first-page":"1309","DOI":"10.1542\/peds.107.6.1309","volume":"107","author":"SL Goldstein","year":"2001","unstructured":"Goldstein SL, Currier H, Graf C, Cosio CC, Brewer ED, Sachdeva R (2001) Outcome in children receiving continuous venovenous hemofiltration. Pediatrics 107:1309\u20131312","journal-title":"Pediatrics"},{"key":"7308_CR6","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2023.49871","volume":"7","author":"KM Gist","year":"2024","unstructured":"Gist KM, Menon S, Anton-Martin P, Bigelow AM, Cortina G, Deep A, De la Mata-Navazo S, Gelbart B, Gorga S, Guzzo I, Mah KE, Ollberding NJ, Shin HS, Thadani S, Uber A, Zang H, Zappitelli M, Selewski DT, WE-ROCK Investigators (2024) Time to continuous renal replacement therapy initiation and 90-day major adverse kidney events in children and young adults. JAMA Netw Open 7:e2349871","journal-title":"JAMA Netw Open"},{"key":"7308_CR7","doi-asserted-by":"publisher","first-page":"1166","DOI":"10.1007\/s00134-011-2231-3","volume":"37","author":"DT Selewski","year":"2011","unstructured":"Selewski DT, Cornell TT, Lombel RM, Blatt NB, Han YY, Mottes T, Kommareddi M, Kershaw DB, Shanley TP, Heung M (2011) Weight-based determination of fluid overload status and mortality in pediatric intensive care unit patients requiring continuous renal replacement therapy. Intensive Care Med 37:1166\u20131173","journal-title":"Intensive Care Med"},{"key":"7308_CR8","doi-asserted-by":"publisher","first-page":"2033","DOI":"10.1007\/s00467-023-06161-z","volume":"39","author":"SM Gorga","year":"2024","unstructured":"Gorga SM, Selewski DT, Goldstein SL, Menon S (2024) An update on the role of fluid overload in the prediction of outcome in acute kidney injury. Pediatr Nephrol 39:2033\u20132048","journal-title":"Pediatr Nephrol"},{"key":"7308_CR9","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1001\/jamapediatrics.2017.4540","volume":"172","author":"R Alobaidi","year":"2018","unstructured":"Alobaidi R, Morgan C, Basu RK, Stenson E, Featherstone R, Majumdar SR, Bagshaw SM (2018) Association between fluid balance and outcomes in critically ill children: a systematic review and meta-analysis. JAMA Pediatr 172:257\u2013268","journal-title":"JAMA Pediatr"},{"key":"7308_CR10","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2024.102714","volume":"74","author":"VC Lintz","year":"2024","unstructured":"Lintz VC, Vieira RA, Carioca FL, Ferraz IS, Silva HM, Ventura AMC, de Souza DC, Brandao MB, Nogueira RJN, de Souza TH (2024) Fluid accumulation in critically ill children: a systematic review and meta-analysis. EClinicalMedicine 74:102714","journal-title":"EClinicalMedicine"},{"key":"7308_CR11","doi-asserted-by":"publisher","first-page":"984","DOI":"10.1016\/S0272-6386(03)00195-1","volume":"41","author":"JM Symons","year":"2003","unstructured":"Symons JM, Brophy PD, Gregory MJ, McAfee N, Somers MJ, Bunchman TE, Goldstein SL (2003) Continuous renal replacement therapy in children up to 10 kg. Am J Kidney Dis 41:984\u2013989","journal-title":"Am J Kidney Dis"},{"key":"7308_CR12","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1097\/PCC.0000000000000043","volume":"15","author":"AB Hassinger","year":"2014","unstructured":"Hassinger AB, Wald EL, Goodman DM (2014) Early postoperative fluid overload precedes acute kidney injury and is associated with higher morbidity in pediatric cardiac surgery patients. Pediatr Crit Care Med 15:131\u2013138","journal-title":"Pediatr Crit Care Med"},{"key":"7308_CR13","doi-asserted-by":"crossref","unstructured":"Brandewie KL, Selewski DT, Bailly DK, Bhat PN, Diddle JW, Ghbeis M, Krawczeski CD, Mah KE, Neumayr TM, Raymond TT, Reichle G, Zang H, Alten JA, NEPHRON investigators (2023) Early postoperative weight-based fluid overload is associated with worse outcomes after neonatal cardiac surgery. Pediatr Nephrol 38:3129\u20133137","DOI":"10.1007\/s00467-023-05929-7"},{"key":"7308_CR14","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1097\/PCC.0000000000002547","volume":"22","author":"L Lima","year":"2021","unstructured":"Lima L, Menon S, Goldstein SL, Basu RK (2021) Timing of fluid overload and association with patient outcome. Pediatr Crit Care Med 22:114\u2013124","journal-title":"Pediatr Crit Care Med"},{"key":"7308_CR15","doi-asserted-by":"publisher","first-page":"2690","DOI":"10.1016\/j.ekir.2023.09.019","volume":"8","author":"SL Goldstein","year":"2023","unstructured":"Goldstein SL, Krallman KA, Roy JP, Collins M, Chima RS, Basu RK, Chawla L, Fei L (2023) Real-time acute kidney injury risk stratification-biomarker directed fluid management improves outcomes in critically ill children and young adults. Kidney Int Rep 8:2690\u20132700","journal-title":"Kidney Int Rep"},{"key":"7308_CR16","doi-asserted-by":"publisher","first-page":"1842","DOI":"10.1016\/j.ekir.2022.05.021","volume":"7","author":"SL Goldstein","year":"2022","unstructured":"Goldstein SL, Krallman KA, Kirby C, Roy JP, Collins M, Fox K, Schmerge A, Wilder S, Gerhardt B, Chima R, Basu RK, Chawla L, Fei L (2022) Integration of the renal angina index and urine neutrophil gelatinase-associated lipocalin improves severe acute kidney injury prediction in critically ill children and young adults. Kidney Int Rep 7:1842\u20131849","journal-title":"Kidney Int Rep"},{"key":"7308_CR17","doi-asserted-by":"publisher","first-page":"1542","DOI":"10.1016\/j.ekir.2023.05.026","volume":"8","author":"S Menon","year":"2023","unstructured":"Menon S, Krallman KA, Arikan AA, Fuhrman DY, Gorga SM, Mottes T, Ollberding N, Ricci Z, Stanski NL, Selewski DT, Soranno DE, Zappitelli M, Zang H, Gist KM, Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease (WE-ROCK) Investigators (2023) Worldwide exploration of renal replacement outcomes collaborative in kidney disease (WE-ROCK). Kidney Int Rep 8:1542\u20131552","journal-title":"Kidney Int Rep"},{"key":"7308_CR18","doi-asserted-by":"publisher","first-page":"1686","DOI":"10.1097\/CCM.0000000000006405","volume":"52","author":"NL Stanski","year":"2024","unstructured":"Stanski NL, Gist KM, Hasson D, Stenson EK, Seo J, Ollberding NJ, Muff-Luett M, Cortina G, Alobaidi R, See E, Kaddourah A, Fuhrman DY, Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease Investigators (2024) Characteristics and outcomes of children and young adults with sepsis requiring continuous renal replacement therapy: a comparative analysis from the Worldwide exploration of renal replacement outcomes collaborative in kidney disease (WE-ROCK). Crit Care Med 52:1686\u20131699","journal-title":"Crit Care Med"},{"key":"7308_CR19","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1053\/j.ajkd.2023.12.017","volume":"84","author":"MC Starr","year":"2024","unstructured":"Starr MC, Gist KM, Zang H, Ollberding NJ, Balani S, Cappoli A, Ciccia E, Joseph C, Kakajiwala A, Kessel A, Muff-Luett M, Santiago Lozano MJ, Pinto M, Reynaud S, Solomon S, Slagle C, Srivastava R, Shih WV, Webb T, Menon S, Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease Collaborative (2024) Continuous kidney replacement therapy and survival in children and young adults: findings from the multinational Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease (WE-ROCK) Collaborative. Am J Kidney Dis 84:406-415 e401","journal-title":"Am J Kidney Dis"},{"key":"7308_CR20","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1159\/000545777","volume":"54","author":"A Basalely","year":"2025","unstructured":"Basalely A, Gist KM, Stanski NL, Fuhrman DY, Seo J, Ollberding NJ, Strong A, Damian M, Morgan C, Reynaud S, Muff-Luett M, Deep A, Serpe C, Krallman KA, Menon S, WE-ROCK Investigators (2025) Thrombocytopenia in children and young adults undergoing continuous renal replacement therapy: a Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease (WE-ROCK) Study. Blood Purif 54:322\u2013333","journal-title":"Blood Purif"},{"key":"7308_CR21","doi-asserted-by":"publisher","first-page":"2957","DOI":"10.1007\/s00467-025-06777-3","volume":"40","author":"S Goswami","year":"2025","unstructured":"Goswami S, Gist KM, Bjornstad P, Ciccia E, Deep A, Gelbart B, Menon S, Marinari E, Ollberding NJ, Qutob D, Seo J, Soranno DE, Van Wyk B, Starr MC, Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease Collaborative (2025) Hyperglycemia and kidney outcomes in critically ill children and young adults on continuous kidney replacement therapy. Pediatr Nephrol 40:2957\u20132966","journal-title":"Pediatr Nephrol"},{"key":"7308_CR22","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1007\/s00467-024-06438-x","volume":"40","author":"S Menon","year":"2025","unstructured":"Menon S, Starr MC, Zang H, Collins M, Damian MA, Fuhrman D, Krallman K, Soranno DE, Webb TN, Slagle C, Joseph C, Martin SD, Mohamed T, Beebe ME, Ricci Z, Ollberding N, Selewski D, Gist KM, Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease (WE-ROCK) investigators (2025) Characteristics and outcomes of children <\/= 10 kg receiving continuous kidney replacement therapy: a WE-ROCK study. Pediatr Nephrol 40:253\u2013264","journal-title":"Pediatr Nephrol"},{"key":"7308_CR23","doi-asserted-by":"publisher","first-page":"1919","DOI":"10.1093\/ndt\/gfaf067","volume":"40","author":"KJ Dolan","year":"2025","unstructured":"Dolan KJ, Gist KM, Basalely A, Bottari G, Chakraborty A, Damian M, Fuhrman D, Hasson DC, Joseph C, Kwiatkowski D, Martin S, Nhan J, Ollberding N, Selewski DT, Soranno D, Starr MC, Strong A, Thadani S, Zang H, Arikan AA, Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease (WE-ROCK) Collaborative (2025) Functional outcomes in pediatric patients on renal replacement therapy in a worldwide registry. Nephrol Dial Transplant 40:1919\u20131930","journal-title":"Nephrol Dial Transplant"},{"key":"7308_CR24","volume":"6","author":"S Thadani","year":"2024","unstructured":"Thadani S, Wu TC, Wu DTY, Kakajiwala A, Soranno DE, Cortina G, Srivastava R, Gist KM, Menon S, Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Diseases Collaborators (2024) Machine learning-based prediction model for ICU mortality after continuous renal replacement therapy initiation in children. Crit Care Explor 6:e1188","journal-title":"Crit Care Explor"},{"key":"7308_CR25","volume":"6","author":"DC Hasson","year":"2024","unstructured":"Hasson DC, Gist KM, Seo J, Stenson EK, Kessel A, Haga T, LaFever S, Santiago MJ, Barhight M, Selewski D, Ricci Z, Ollberding NJ, Stanski NL, Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease Collaborative (2024) The association between vasopressin and adverse kidney outcomes in children and young adults requiring vasopressors on continuous renal replacement therapy. Crit Care Explor 6:e1156","journal-title":"Crit Care Explor"},{"key":"7308_CR26","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1007\/s00134-024-07336-4","volume":"50","author":"EK Stenson","year":"2024","unstructured":"Stenson EK, Alhamoud I, Alobaidi R, Bottari G, Fernandez S, Fuhrman DY, Guzzi F, Haga T, Kaddourah A, Marinari E, Mohamed T, Morgan C, Mottes T, Neumayr T, Ollberding NJ, Raggi V, Ricci Z, See E, Stanski NL, Zang H, Zangla E, Gist KM, Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease (WE-ROCK) Investigators (2024) Factors associated with successful liberation from continuous renal replacement therapy in children and young adults: analysis of the worldwide exploration of renal replacement outcomes collaborative in Kidney Disease Registry. Intensive Care Med 50:861\u2013872","journal-title":"Intensive Care Med"},{"key":"7308_CR27","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.0243","volume":"7","author":"DY Fuhrman","year":"2024","unstructured":"Fuhrman DY, Stenson EK, Alhamoud I, Alobaidi R, Bottari G, Fernandez S, Guzzi F, Haga T, Kaddourah A, Marinari E, Mohamed TH, Morgan CJ, Mottes T, Neumayr TM, Ollberding NJ, Raggi V, Ricci Z, See E, Stanski NL, Zang H, Zangla E, Gist KM, Worldwide Exploration of Renal Replacement Outcomes Collaborative in Kidney Disease (WE-ROCK) Investigators (2024) Major adverse kidney events in pediatric continuous kidney replacement therapy. JAMA Netw Open 7:e240243","journal-title":"JAMA Netw Open"},{"key":"7308_CR28","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1016\/j.jclinepi.2007.11.008","volume":"61","author":"E von Elm","year":"2008","unstructured":"von Elm E, Altman DG, Egger M, Pocock SJ, Gotzsche PC, Vandenbroucke JP, STROBE Initiative (2008) The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies. J Clin Epidemiol 61:344\u2013349","journal-title":"J Clin Epidemiol"},{"key":"7308_CR29","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1007\/s40124-023-00286-3","volume":"11","author":"M Miranda","year":"2023","unstructured":"Miranda M, Nadel S (2023) Pediatric sepsis: a summary of current definitions and management recommendations. Curr Pediatr Rep 11:29\u201339","journal-title":"Curr Pediatr Rep"},{"key":"7308_CR30","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1097\/PCC.0b013e3181b806fc","volume":"11","author":"MG Gaies","year":"2010","unstructured":"Gaies MG, Gurney JG, Yen AH, Napoli ML, Gajarski RJ, Ohye RG, Charpie JR, Hirsch JC (2010) Vasoactive-inotropic score as a predictor of morbidity and mortality in infants after cardiopulmonary bypass. Pediatr Crit Care Med 11:234\u2013238","journal-title":"Pediatr Crit Care Med"},{"key":"7308_CR31","doi-asserted-by":"publisher","first-page":"1761","DOI":"10.1097\/CCM.0b013e31828a2bbd","volume":"41","author":"S Leteurtre","year":"2013","unstructured":"Leteurtre S, Duhamel A, Salleron J, Grandbastien B, Lacroix J, Leclerc F, Groupe Francophone R\u00e9animation et d\u2019Urgences P\u00e9diatriques (GFRUP) (2013) PELOD-2: an update of the pediatric logistic organ dysfunction score. Crit Care Med 41:1761\u20131773","journal-title":"Crit Care Med"},{"key":"7308_CR32","doi-asserted-by":"publisher","first-page":"1772","DOI":"10.1097\/00003246-200208000-00016","volume":"30","author":"DA Schoenfeld","year":"2002","unstructured":"Schoenfeld DA, Bernard GR, ARDS Network (2002) Statistical evaluation of ventilator-free days as an efficacy measure in clinical trials of treatments for acute respiratory distress syndrome. Crit Care Med 30:1772\u20131777","journal-title":"Crit Care Med"},{"key":"7308_CR33","volume-title":"R: a language and environment for statistical computing","author":"R Core Team","year":"2025","unstructured":"R Core Team (2025) R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria"},{"key":"7308_CR34","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1007\/s00467-022-05584-4","volume":"38","author":"DR Nelson","year":"2023","unstructured":"Nelson DR, Keswani M, Finn L, Mahoney K, Genualdi L, Barhight MF (2023) A quality initiative to improve recognition of fluid overload among pediatric ICU patients requiring continuous kidney replacement therapy: preliminary results. Pediatr Nephrol 38:557\u2013564","journal-title":"Pediatr Nephrol"},{"key":"7308_CR35","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2020.00080","volume":"8","author":"TA Mottes","year":"2020","unstructured":"Mottes TA (2020) Does your program know its AKI and CRRT epidemiology? The case for a dashboard. Front Pediatr 8:80","journal-title":"Front Pediatr"},{"key":"7308_CR36","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/s12882-018-1195-8","volume":"20","author":"TA Mottes","year":"2019","unstructured":"Mottes TA, Goldstein SL, Basu RK (2019) Process based quality improvement using a continuous renal replacement therapy dashboard. BMC Nephrol 20:17","journal-title":"BMC Nephrol"},{"key":"7308_CR37","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1007\/s00467-020-04828-5","volume":"36","author":"DT Selewski","year":"2021","unstructured":"Selewski DT, Askenazi DJ, Kashani K, Basu RK, Gist KM, Harer MW, Jetton JG, Sutherland SM, Zappitelli M, Ronco C, Goldstein SL, Mottes TA (2021) Quality improvement goals for pediatric acute kidney injury: pediatric applications of the 22nd Acute Disease Quality Initiative (ADQI) conference. Pediatr Nephrol 36:733\u2013746","journal-title":"Pediatr Nephrol"},{"key":"7308_CR38","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1007\/s00134-012-2503-6","volume":"38","author":"RM Lombel","year":"2012","unstructured":"Lombel RM, Kommareddi M, Mottes T, Selewski DT, Han YY, Gipson DS, Collins KL, Heung M (2012) Implications of different fluid overload definitions in pediatric stem cell transplant patients requiring continuous renal replacement therapy. Intensive Care Med 38:663\u2013669","journal-title":"Intensive Care Med"}],"container-title":["Pediatric Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-026-07308-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00467-026-07308-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-026-07308-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:47:38Z","timestamp":1786978058000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00467-026-07308-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,29]]},"references-count":38,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["7308"],"URL":"https:\/\/doi.org\/10.1007\/s00467-026-07308-4","relation":{},"ISSN":["0931-041X","1432-198X"],"issn-type":[{"value":"0931-041X","type":"print"},{"value":"1432-198X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,29]]},"assertion":[{"value":"3 January 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 February 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 March 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 April 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Katja Gist receives funding from the Gerber Foundation for the \u201cMini-Rocket study,\u201d Katja Gist is a consultant for Seastar Medical and Altathera Medical. Katja Gist is a speaker for Fresenius Medical. David Selewski is a speaker for Bioporto. David Selewski is an associate editor for\n                      Pediatric Nephrology\n                      and a guest editor for the special issue on\n                      Neonatal Nephrology\n                      in the journal. David Askenazi is a consultant for Seastar Medical and Nuwellis and is the Chief Scientific Officer for Zorro-Flow Inc.","order":1,"name":"Ethics","label":"Disclosures","group":{"name":"EthicsHeading","label":"Declarations"}}]}}