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Despite this, limited longitudinal data exist regarding ambulatory blood pressure monitoring (ABPM) and cardiac outcomes in children and young people (CYP) initiating dialysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This is a retrospective, longitudinal study of CYP age 5\u201318 with paired echocardiogram and ABPM evaluations over 12 months (\u201cbaseline\u201d to \u201cfollow-up\u201d) following dialysis initiation. Left ventricular hypertrophy (LVH) was defined by age-specific indexed left ventricular mass (LVMI) and LV mass-for-height z-score\u2009\u2265\u200995th percentile. Hypertension was defined if day, night, or 24-h ABPM\u2009\u2265\u200995th percentile and CYP was categorised as having persistent hypertension, resolved hypertension, persistent normotension, or emergent hypertension.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were 32 CYP, with a mean age of 12.7\u2009\u00b1\u20093.1\u00a0years. LVH was present in 37.5% at baseline and 25% at follow-up. LVH rates improved on haemodialysis (baseline 52.9%, follow-up 17.6%,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.031), but not on peritoneal dialysis. Higher rates of hypertension were found in LVH versus no LVH at follow-up. Masked hypertension rates was present in 14 (43.8%)\u00a0at both\u00a0baseline and follow-up. Mean LVMI was higher in persistently hypertensive versus persistently normotensive CYP at follow-up. \u0394LVMI was independently associated with LVH at baseline (yes\/no) (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u2009\u22120.482,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.001), and \u0394log N-terminal pro-brain b-type natriuretic peptide (NT Pro-BNP) (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2009=\u20090.412,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.005).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>CYP with persistent hypertension had worst rates of LVH and indexed LV mass. A correlation between changes in NT Pro-BNP and LVMI highlights a probable role of fluid overload. Further research into using NT Pro-BNP as a biomarker to improve hypertension management is warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00467-026-07351-1","type":"journal-article","created":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T22:17:51Z","timestamp":1779488271000},"page":"3595-3604","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hypertension control and its association with left ventricular hypertrophy in children and young people on dialysis: a longitudinal study"],"prefix":"10.1007","volume":"41","author":[{"given":"Gordon","family":"Bruce","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravsimrat","family":"Chawla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Savis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Samuels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Newton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John M.","family":"Simpson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7593-1203","authenticated-orcid":false,"given":"Manish D.","family":"Sinha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,23]]},"reference":[{"key":"7351_CR1","doi-asserted-by":"publisher","first-page":"1355","DOI":"10.1016\/j.kint.2016.02.016","volume":"89","author":"NC Chesnaye","year":"2016","unstructured":"Chesnaye NC, Schaefer F, Groothoff JW et al (2016) Mortality risk in European children with end-stage renal disease on dialysis. 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