{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T07:51:58Z","timestamp":1781855518663,"version":"3.54.5"},"reference-count":59,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T00:00:00Z","timestamp":1781827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T00:00:00Z","timestamp":1781827200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Pediatr Nephrol"],"DOI":"10.1007\/s00467-026-07406-3","type":"journal-article","created":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T07:05:04Z","timestamp":1781852704000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hemoadsorption in acute pediatric carbamazepine intoxication: a case report and systematic review of extracorporeal therapies"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7939-3729","authenticated-orcid":false,"given":"Davide","family":"Visentin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-0026-8945","authenticated-orcid":false,"given":"Germana","family":"Longo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6036-1954","authenticated-orcid":false,"given":"Anna","family":"Tessari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3127-8836","authenticated-orcid":false,"given":"Marco","family":"Daverio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3665-1159","authenticated-orcid":false,"given":"Jos\u00e8 Maria","family":"Igeno San Miguel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3963-0803","authenticated-orcid":false,"given":"Enrico","family":"Vidal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5654-0506","authenticated-orcid":false,"given":"Angela","family":"Amigoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6266-3665","authenticated-orcid":false,"given":"Claudia Maria","family":"Bonardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,19]]},"reference":[{"key":"7406_CR1","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/bs.podrm.2015.11.001","volume":"41","author":"ST Alrashood","year":"2016","unstructured":"Alrashood ST (2016) Chapter Three - Carbamazepine. Profiles Drug Subst Excip Relat Methodol 41:133\u2013321. https:\/\/doi.org\/10.1016\/bs.podrm.2015.11.001","journal-title":"Profiles Drug Subst Excip Relat Methodol"},{"key":"7406_CR2","unstructured":"Maan JS, Duong TVH, Saadabadi A (2023) Carbamazepine [Updated 10 Jul 2023]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK482455\/Accessed 19 Feb 2026"},{"key":"7406_CR3","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1093\/tropej\/fmn117","volume":"55","author":"V Nair","year":"2009","unstructured":"Nair V, Mahadevan S (2009) Randomised controlled study\u2014efficacy of clonidine versus carbamazepine in children with ADHD. J Trop Pediatr 55:116\u2013121. https:\/\/doi.org\/10.1093\/tropej\/fmn117","journal-title":"J Trop Pediatr"},{"issue":"18","key":"7406_CR4","doi-asserted-by":"publisher","first-page":"9835","DOI":"10.3390\/ijms25189835","volume":"25","author":"A S\u00e1 Filho","year":"2024","unstructured":"S\u00e1 Filho A, Martins JLR, Costa RF, Pedrino GR, Duarte VS, Silva ON, Napolitano HB, Fajemiroye JO (2024) Polymorphism and pharmacological assessment of carbamazepine. Int J Mol Sci 25:9835. https:\/\/doi.org\/10.3390\/ijms25189835","journal-title":"Int J Mol Sci"},{"key":"7406_CR5","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1111\/jpc.13833","volume":"54","author":"S Ferranti","year":"2018","unstructured":"Ferranti S, Grande E, Gaggiano C, Grosso S (2018) Antiepileptic drugs: role in paediatric poisoning. J Paediatr Child Health 54:475\u2013479. https:\/\/doi.org\/10.1111\/jpc.13833","journal-title":"J Paediatr Child Health"},{"key":"7406_CR6","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1080\/15563650.2021.2023747","volume":"60","author":"MS Toce","year":"2022","unstructured":"Toce MS, Hudgins JD, Yuskaitis CJ, Monuteaux MC, Bourgeois FT (2022) National assessment of anti-epileptic drug exposures among pre-teens and adolescents, 2000-2020. Clin Toxicol (Phila) 60:681\u2013687. https:\/\/doi.org\/10.1080\/15563650.2021.2023747","journal-title":"Clin Toxicol (Phila)"},{"key":"7406_CR7","doi-asserted-by":"publisher","first-page":"4729","DOI":"10.12659\/MSM.898899","volume":"22","author":"M Acikgoz","year":"2016","unstructured":"Acikgoz M, Paksu MS, Guzel A, Alacam A, Alacam F (2016) Severe carbamazepine intoxication in children: analysis of a 40-case series. Med Sci Monit 22:4729\u20134735. https:\/\/doi.org\/10.12659\/MSM.898899","journal-title":"Med Sci Monit"},{"key":"7406_CR8","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1007\/BF00936891","volume":"242","author":"S Schmidt","year":"1995","unstructured":"Schmidt S, Schmitz-Buhl M (1995) Signs and symptoms of carbamazepine overdose. J Neurol 242:169\u2013173. https:\/\/doi.org\/10.1007\/BF00936891","journal-title":"J Neurol"},{"key":"7406_CR9","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1097\/00006565-200002000-00008","volume":"16","author":"M Lifshitz","year":"2000","unstructured":"Lifshitz M, Gavrilov V, Sofer S (2000) Signs and symptoms of carbamazepine overdose in young children. Pediatr Emerg Care 16:26\u201327. https:\/\/doi.org\/10.1097\/00006565-200002000-00008","journal-title":"Pediatr Emerg Care"},{"key":"7406_CR10","doi-asserted-by":"publisher","first-page":"445","DOI":"10.3109\/15563659009038587","volume":"28","author":"HA Spiller","year":"1990","unstructured":"Spiller HA, Krenzelok EP, Cookson E (1990) Carbamazepine overdose: a prospective study of serum levels and toxicity. J Toxicol Clin Toxicol 28:445\u2013458. https:\/\/doi.org\/10.3109\/15563659009038587","journal-title":"J Toxicol Clin Toxicol"},{"key":"7406_CR11","doi-asserted-by":"publisher","first-page":"341","DOI":"10.2165\/00003088-199529050-00004","volume":"29","author":"D Battino","year":"1995","unstructured":"Battino D, Estienne M, Avanzini G (1995) Clinical pharmacokinetics of antiepileptic drugs in paediatric patients. Clin Pharmacokinet 29:341\u2013369. https:\/\/doi.org\/10.2165\/00003088-199529050-00004","journal-title":"Clin Pharmacokinet"},{"key":"7406_CR12","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1046\/j.1442-2026.2002.00290.x","volume":"14","author":"A Graudins","year":"2002","unstructured":"Graudins A, Peden G, Dowsett RP (2002) Massive overdose with controlled-release carbamazepine resulting in delayed peak serum concentrations and life-threatening toxicity. Emerg Med (Fremantle) 14:89\u201394. https:\/\/doi.org\/10.1046\/j.1442-2026.2002.00290.x","journal-title":"Emerg Med (Fremantle)"},{"key":"7406_CR13","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1097\/MJT.0b013e3182258e51","volume":"20","author":"VH Patel","year":"2013","unstructured":"Patel VH, Schindlbeck MA, Bryant SM (2013) Delayed elevation in carbamazepine concentrations after overdose: a retrospective poison center study. Am J Ther 20:602\u2013606. https:\/\/doi.org\/10.1097\/MJT.0b013e3182258e51","journal-title":"Am J Ther"},{"key":"7406_CR14","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1080\/15563650.2018.1513138","volume":"57","author":"LCG Hoegberg","year":"2019","unstructured":"Hoegberg LCG, Refsgaard F, Pedersen SH, Personne M, Ullah S, Panagiotidis G, Petersen TS, Annas A (2019) Potential pharmacobezoar formation of large size extended-release tablets and their dissolution - an in vitro study. Clin Toxicol (Phila) 57:271\u2013281. https:\/\/doi.org\/10.1080\/15563650.2018.1513138","journal-title":"Clin Toxicol (Phila)"},{"key":"7406_CR15","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.1345\/aph.1K162","volume":"41","author":"Y Lurie","year":"2007","unstructured":"Lurie Y, Bentur Y, Levy Y, Baum E, Krivoy N (2007) Limited efficacy of gastrointestinal decontamination in severe slow-release carbamazepine overdose. Ann Pharmacother 41:1539\u20131543. https:\/\/doi.org\/10.1345\/aph.1K162","journal-title":"Ann Pharmacother"},{"key":"7406_CR16","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1097\/00006565-200112000-00015","volume":"17","author":"HA Spiller","year":"2001","unstructured":"Spiller HA (2001) Management of carbamazepine overdose. Pediatr Emerg Care 17:452\u2013456. https:\/\/doi.org\/10.1097\/00006565-200112000-00015","journal-title":"Pediatr Emerg Care"},{"key":"7406_CR17","doi-asserted-by":"publisher","first-page":"816","DOI":"10.5498\/wjp.v13.i11.816","volume":"13","author":"L Wang","year":"2023","unstructured":"Wang L, Wang Y, Zhang RY, Wang Y, Liang W, Li TG (2023) Management of acute carbamazepine poisoning: a narrative review. World J Psychiatry 13:816\u2013830. https:\/\/doi.org\/10.5498\/wjp.v13.i11.816","journal-title":"World J Psychiatry"},{"issue":"1","key":"7406_CR18","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1186\/1865-1380-4-65","volume":"4","author":"TE Albertson","year":"2011","unstructured":"Albertson TE, Owen KP, Sutter ME, Chan AL (2011) Gastrointestinal decontamination in the acutely poisoned patient. Int J Emerg Med 4:65. https:\/\/doi.org\/10.1186\/1865-1380-4-65","journal-title":"Int J Emerg Med"},{"key":"7406_CR19","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1111\/bcp.16379","volume":"91","author":"S Gosselin","year":"2025","unstructured":"Gosselin S, Hoegberg LCG, Hoffman RS (2025) Gut decontamination in the poisoned patient. Br J Clin Pharmacol 91:595\u2013603. https:\/\/doi.org\/10.1111\/bcp.16379","journal-title":"Br J Clin Pharmacol"},{"key":"7406_CR20","doi-asserted-by":"publisher","first-page":"993","DOI":"10.3109\/15563650.2014.973572","volume":"52","author":"M Ghannoum","year":"2014","unstructured":"Ghannoum M, Yates C, Galvao TF, Sowinski KM, Vo TH, Coogan A, Gosselin S, Lavergne V, Nolin TD, Hoffman RS (2014) Extracorporeal treatment for carbamazepine poisoning: systematic review and recommendations from the EXTRIP workgroup. Clin Toxicol (Phila) 52:993\u20131004. https:\/\/doi.org\/10.3109\/15563650.2014.973572","journal-title":"Clin Toxicol (Phila)"},{"key":"7406_CR21","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1016\/j.kint.2018.03.026","volume":"94","author":"M Ghannoum","year":"2018","unstructured":"Ghannoum M, Hoffman RS, Gosselin S, Nolin TD, Lavergne V, Roberts DM (2018) Use of extracorporeal treatments in the management of poisonings. Kidney Int 94:682\u2013688. https:\/\/doi.org\/10.1016\/j.kint.2018.03.026","journal-title":"Kidney Int"},{"key":"7406_CR22","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1007\/s00467-023-05937-7","volume":"39","author":"K Deville","year":"2024","unstructured":"Deville K, Charlton N, Askenazi D (2024) Use of extracorporeal therapies to treat life-threatening intoxications. Pediatr Nephrol 39:105\u2013113. https:\/\/doi.org\/10.1007\/s00467-023-05937-7","journal-title":"Pediatr Nephrol"},{"key":"7406_CR23","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1159\/000182054","volume":"27","author":"NE Gary","year":"1981","unstructured":"Gary NE, Byra WM, Eisinger RP (1981) Carbamazepine poisoning: treatment by hemoperfusion. Nephron 27:202\u2013203. https:\/\/doi.org\/10.1159\/000182054","journal-title":"Nephron"},{"key":"7406_CR24","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1177\/106002808902300206","volume":"23","author":"RJ Kandrotas","year":"1989","unstructured":"Kandrotas RJ, Oles KS, Gal P, Love JM (1989) Carbamazepine clearance in hemodialysis and hemoperfusion. DICP 23:137\u2013140. https:\/\/doi.org\/10.1177\/106002808902300206","journal-title":"DICP"},{"key":"7406_CR25","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1111\/j.1523-1755.2005.00469.x","volume":"68","author":"TW Meyer","year":"2005","unstructured":"Meyer TW, Walther JL, Pagtalunan ME, Martinez AW, Torkamani A, Fong PD, Recht NS, Robertson CR, Hostetter TH (2005) The clearance of protein-bound solutes by hemofiltration and hemodiafiltration. Kidney Int 68:867\u2013877. https:\/\/doi.org\/10.1111\/j.1523-1755.2005.00469.x","journal-title":"Kidney Int"},{"key":"7406_CR26","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1016\/j.ajem.2017.10.048","volume":"36","author":"X Yang","year":"2018","unstructured":"Yang X, Xin S, Zhang Y, Li T (2018) Early hemoperfusion for emergency treatment of carbamazepine poisoning. Am J Emerg Med 36:926\u2013930. https:\/\/doi.org\/10.1016\/j.ajem.2017.10.048","journal-title":"Am J Emerg Med"},{"key":"7406_CR27","doi-asserted-by":"publisher","first-page":"484","DOI":"10.5414\/CNP57484","volume":"57","author":"JT Kielstein","year":"2002","unstructured":"Kielstein JT, Schwarz A, Arnavaz A, Sehlberg O, Emrich HM, Fliser D (2002) High-flux hemodialysis\u2014an effective alternative to hemoperfusion in the treatment of carbamazepine intoxication. Clin Nephrol 57:484\u2013486. https:\/\/doi.org\/10.5414\/CNP57484","journal-title":"Clin Nephrol"},{"key":"7406_CR28","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.57657","volume":"8","author":"G Bottari","year":"2025","unstructured":"Bottari G, Buccione E, Bayrakci B, Briassoulis G, Carter MJ, Demirkol D, Ilia S, Morin L, Reiter K, Santiago MJ, Schlapbach LJ, Slocker-Barrio M, Tissieres P, Zaoral T, Bianzina S, Deep A (2025) Extracorporeal blood purification in European pediatric intensive care units: a consensus statement. JAMA Netw Open 8:e2457657. https:\/\/doi.org\/10.1001\/jamanetworkopen.2024.57657","journal-title":"JAMA Netw Open"},{"key":"7406_CR29","doi-asserted-by":"publisher","DOI":"10.1159\/000545804","author":"I Lemagnen","year":"2025","unstructured":"Lemagnen I, Monard C, Palluau M, Bergamaschi L, Furukawa T, Bellomo R, Schneider A (2025) Drug removal by hemoadsorption. Blood Purif. https:\/\/doi.org\/10.1159\/000545804","journal-title":"Blood Purif"},{"key":"7406_CR30","doi-asserted-by":"publisher","first-page":"1444","DOI":"10.1111\/jcpt.13724","volume":"47","author":"D Mitrovic","year":"2022","unstructured":"Mitrovic D, Huntjens DW, de Vos EAJ, van Tellingen M, Franssen EJF (2022) Extracorporeal hemoadsorption with the CytoSorb device as a potential therapeutic option in severe intoxications: review of the rationale and current clinical experiences. J Clin Pharm Ther 47:1444\u20131451. https:\/\/doi.org\/10.1111\/jcpt.13724","journal-title":"J Clin Pharm Ther"},{"key":"7406_CR31","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71","volume":"372","author":"MJ Page","year":"2021","unstructured":"Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, Chou R, Glanville J, Grimshaw JM, Hr\u00f3bjartsson A, Lalu MM, Li T, Loder EW, Mayo-Wilson E, McDonald S, McGuinness LA, Stewart LA, Thomas J, Tricco AC, Welch VA, Whiting P, Moher D (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 372:n71. https:\/\/doi.org\/10.1136\/bmj.n71","journal-title":"BMJ"},{"key":"7406_CR32","doi-asserted-by":"publisher","unstructured":"Moola S, Munn Z, Tufanaru C, Aromataris E, Sears K, Sfetcu R, Currie M, Lisy K, Qureshi R, Mattis P, Mu P (2020) Chapter 7: systematic reviews of etiology and risk. In: Aromataris E, Munn Z (eds) JBI Manual for Evidence Synthesis. JBI. Available from: https:\/\/synthesismanual.jbi.global. https:\/\/doi.org\/10.46658\/JBIMES-20-08","DOI":"10.46658\/JBIMES-20-08"},{"key":"7406_CR33","doi-asserted-by":"publisher","first-page":"2127","DOI":"10.11124\/JBISRIR-D-19-00099","volume":"18","author":"Z Munn","year":"2020","unstructured":"Munn Z, Barker TH, Moola S, Tufanaru C, Stern C, McArthur A, Stephenson M, Aromataris E (2020) Methodological quality of case series studies: an introduction to the JBI critical appraisal tool. JBI Evid Synth 18:2127\u20132133. https:\/\/doi.org\/10.11124\/JBISRIR-D-19-00099","journal-title":"JBI Evid Synth"},{"key":"7406_CR34","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/S0022-3476(05)81208-9","volume":"3476","author":"J Tibballs","year":"1992","unstructured":"Tibballs J (1992) Acute toxic reaction to carbamazepine: clinical effects and serum concentrations. J Pediatr 3476:295\u2013299. https:\/\/doi.org\/10.1016\/S0022-3476(05)81208-9","journal-title":"J Pediatr"},{"key":"7406_CR35","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1007\/s004670050698","volume":"13","author":"G Deshpande","year":"1999","unstructured":"Deshpande G, Meert KL, Valentini RP (1999) Repeat charcoal hemoperfusion treatments in life threatening carbamazepine overdose. Pediatr Nephrol 13:775\u2013777. https:\/\/doi.org\/10.1007\/s004670050698","journal-title":"Pediatr Nephrol"},{"key":"7406_CR36","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1081\/clt-100100938","volume":"38","author":"DJE Schuerer","year":"2000","unstructured":"Schuerer DJE, Brophy PD, Maxvold NJ, Kudelka T, Bunchman TE (2000) High-efficiency dialysis for carbamazepine overdose. J Toxicol Clin Toxicol 38:321\u2013323. https:\/\/doi.org\/10.1081\/clt-100100938","journal-title":"J Toxicol Clin Toxicol"},{"key":"7406_CR37","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1191\/096032701678766831","volume":"20","author":"A Duzova","year":"2001","unstructured":"Duzova A, Baskin E, Usta Y, Ozen S (2001) Carbamazepine poisoning: treatment with plasma exchange. Hum Exp Toxicol 20:175\u2013177. https:\/\/doi.org\/10.1191\/096032701678766831","journal-title":"Hum Exp Toxicol"},{"key":"7406_CR38","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1081\/clt-120006754","volume":"40","author":"RJ Cameron","year":"2002","unstructured":"Cameron RJ, Hungerford P, Dawson AH (2002) Efficacy of charcoal hemoperfusion in massive carbamazepine poisoning. J Toxicol Clin Toxicol 40:507\u2013512. https:\/\/doi.org\/10.1081\/clt-120006754","journal-title":"J Toxicol Clin Toxicol"},{"key":"7406_CR39","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1542\/peds.113.2.406","volume":"113","author":"DJ Askenazi","year":"2004","unstructured":"Askenazi DJ, Goldstein SL, Chang IF, Elenberg E, Feig DI (2004) Management of a severe carbamazepine overdose using albumin-enhanced continuous venovenous hemodialysis. Pediatrics 113:406\u2013409. https:\/\/doi.org\/10.1542\/peds.113.2.406","journal-title":"Pediatrics"},{"key":"7406_CR40","doi-asserted-by":"publisher","first-page":"1176","DOI":"10.1111\/j.1460-9592.2006.01955.x","volume":"16","author":"TS Yildiz","year":"2006","unstructured":"Yildiz TS, Toprak DG, Arisoy ES, Solak M, Toker K (2006) Continuous venovenous hemodiafiltration to treat controlled-release carbamazepine overdose in a pediatric patient. Paediatr Anaesth 16:1176\u20131178. https:\/\/doi.org\/10.1111\/j.1460-9592.2006.01955.x","journal-title":"Paediatr Anaesth"},{"key":"7406_CR41","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1111\/j.1440-1797.2006.00663.x","volume":"12","author":"K Bek","year":"2007","unstructured":"Bek K, Ko\u00e7ak S, \u00d6zkaya O, Y\u0131lmaz Y, Ayd\u0131n \u00d6F, Ta\u015fd\u00f6ven CS (2007) Carbamazepine poisoning managed with haemodialysis and haemoperfusion in three adolescents. Nephrology (Carlton) 12:33\u201335. https:\/\/doi.org\/10.1111\/j.1440-1797.2006.00663.x","journal-title":"Nephrology (Carlton)"},{"key":"7406_CR42","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1016\/j.ajem.2009.06.013","volume":"28","author":"U Goktas","year":"2010","unstructured":"Goktas U, Kati I, Yuce HH (2010) Management of a severe carbamazepine overdose with continuous venovenous hemodiafiltration. Am J Emerg Med 28:e1-260. https:\/\/doi.org\/10.1016\/j.ajem.2009.06.013","journal-title":"Am J Emerg Med"},{"key":"7406_CR43","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1007\/s00134-012-2717-7","volume":"39","author":"JS Choi","year":"2013","unstructured":"Choi JS, Kim CS, Bae EH, Ma SK, Kee SJ, Woo YJ, Kim SW (2013) Enhanced clearance of carbamazepine using albumin-containing dialysate during CVVHDF. Intensive Care Med 39:159\u2013160. https:\/\/doi.org\/10.1007\/s00134-012-2717-7","journal-title":"Intensive Care Med"},{"key":"7406_CR44","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1016\/j.jemermed.2012.12.018","volume":"44","author":"MA Darracq","year":"2013","unstructured":"Darracq MA, Cantrell FL (2013) Hemodialysis and extracorporeal removal after pediatric and adolescent poisoning reported to a state poison center. J Emerg Med 44:1101\u20131107. https:\/\/doi.org\/10.1016\/j.jemermed.2012.12.018","journal-title":"J Emerg Med"},{"key":"7406_CR45","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1111\/hdi.12132","volume":"18","author":"YK Chung","year":"2014","unstructured":"Chung YK, Chang KY, Park HS, Kim MH, Lee KM, Lim TS, Kim HW (2014) Severe carbamazepine intoxication unresponsive to albumin-enhanced continuous venovenous hemodiafiltration with low dialysate flow. Hemodial Int 18:551\u2013555. https:\/\/doi.org\/10.1111\/hdi.12132","journal-title":"Hemodial Int"},{"key":"7406_CR46","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1002\/jca.21305","volume":"29","author":"I Kozanoglu","year":"2014","unstructured":"Kozanoglu I, Kahveci S, Asma S, Yeral M, Noyan A, Boga C, Ozdogu H (2014) Plasma-exchange treatment for severe carbamazepine intoxication: a case study. J Clin Apher 29:178\u2013180. https:\/\/doi.org\/10.1002\/jca.21305","journal-title":"J Clin Apher"},{"key":"7406_CR47","doi-asserted-by":"publisher","first-page":"bcr2014207761","DOI":"10.1136\/bcr-2014-207761","volume":"2014","author":"R Moinho","year":"2014","unstructured":"Moinho R, Dias A, Estanqueiro P, Farela Neves J (2014) Overdose with antiepileptic drugs: the efficacy of extracorporeal removal techniques. BMJ Case Rep 2014:bcr2014207761. https:\/\/doi.org\/10.1136\/bcr-2014-207761","journal-title":"BMJ Case Rep"},{"key":"7406_CR48","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2016-1560","volume":"139","author":"A Agulnik","year":"2017","unstructured":"Agulnik A, Kelly DP, Bruccoleri RC, Yuskaitis CS, Ebrahimi-Fakhari D, Sahin M, Burns MM, Kohane DS (2017) Combination clearance therapy and barbiturate coma for severe carbamazepine overdose. Pediatrics 139:e20161560. https:\/\/doi.org\/10.1542\/peds.2016-1560","journal-title":"Pediatrics"},{"key":"7406_CR49","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1097\/WNF.0000000000000206","volume":"40","author":"B Chauhan","year":"2017","unstructured":"Chauhan B, Patanvadiya A, Dash GK (2017) Carbamazepine toxicity-induced spindle coma: a novel case report. Clin Neuropharmacol 40:100\u2013102. https:\/\/doi.org\/10.1097\/WNF.0000000000000206","journal-title":"Clin Neuropharmacol"},{"key":"7406_CR50","doi-asserted-by":"publisher","first-page":"3201203","DOI":"10.1155\/2018\/3201203","volume":"2018","author":"W Xu","year":"2018","unstructured":"Xu W, Chen YL, Zhao Y, Wang LJ, Li JJ, Liu CF (2018) A clinical study of toxication caused by carbamazepine abuse in adolescents. Biomed Res Int 2018:3201203. https:\/\/doi.org\/10.1155\/2018\/3201203","journal-title":"Biomed Res Int"},{"key":"7406_CR51","doi-asserted-by":"publisher","first-page":"e988","DOI":"10.1097\/PCC.0000000000002462","volume":"21","author":"M \u00d6zkale","year":"2020","unstructured":"\u00d6zkale M, \u00d6zkale Y (2020) The role of therapeutic plasma exchange in the treatment of childhood intoxication: a single-center experience. Pediatr Crit Care Med 21:e988\u2013e995. https:\/\/doi.org\/10.1097\/PCC.0000000000002462","journal-title":"Pediatr Crit Care Med"},{"key":"7406_CR52","doi-asserted-by":"publisher","first-page":"205","DOI":"10.2147\/IMCRJ.S358084","volume":"15","author":"MA Nasif","year":"2022","unstructured":"Nasif MA, Falana HH, Hamed HKH, Yousef QGH, Jaradat MA (2022) Severe carbamazepine toxicity treated with continuous venovenous hemofiltration at Palestine Medical Complex: two case reports. Int Med Case Rep J 15:205\u2013208. https:\/\/doi.org\/10.2147\/IMCRJ.S358084","journal-title":"Int Med Case Rep J"},{"key":"7406_CR53","doi-asserted-by":"publisher","DOI":"10.1177\/2050313X241229844","volume":"12","author":"H Abdullah-Koolmees","year":"2024","unstructured":"Abdullah-Koolmees H, Mekel VCC, Veldkamp AI, Caris MG, Swart EL (2024) A case report: management of carbamazepine intoxication using hemodialysis followed by continuous venovenous hemodialysis. SAGE Open Med Case Rep 12:2050313X241229844. https:\/\/doi.org\/10.1177\/2050313X241229844","journal-title":"SAGE Open Med Case Rep"},{"key":"7406_CR54","doi-asserted-by":"publisher","unstructured":"Klinkmann G, Reis T, Ronco C; Studies Utilizing Blood Purification in Limiting the Overdose in Treatments (SUBPLOT) Investigators (2026) Correspondence regarding the article by H\u00fcser et al. on \u201cCritical care management of the patient with pharmaceutical poisoning\u201d. Intensive Care Med. https:\/\/doi.org\/10.1007\/s00134-025-08279-0","DOI":"10.1007\/s00134-025-08279-0"},{"issue":"23","key":"7406_CR55","doi-asserted-by":"publisher","first-page":"7199","DOI":"10.3390\/jcm12237199","volume":"12","author":"S Mitzner","year":"2023","unstructured":"Mitzner S, Kogelmann K, Ince C, Moln\u00e1r Z, Ferrer R, Nierhaus A (2023) Adjunctive hemoadsorption therapy with CytoSorb in patients with septic\/vasoplegic shock: a best practice consensus statement. J Clin Med 12:7199. https:\/\/doi.org\/10.3390\/jcm12237199","journal-title":"J Clin Med"},{"key":"7406_CR56","unstructured":"CytoSorbents Corporation (2024) CytoSorb\u00ae Guide (Practice Manual). Document No. B1031R13ENG2024, Rev. R13. Princeton (NJ): CytoSorbents Corporation. Available from: https:\/\/downloads.cytosorbents.com\/241217_CytoSorbGuide-ENG_B1031R13ENG2024_WEB.pdf Accessed 19 Feb 2026"},{"key":"7406_CR57","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1007\/s00467-025-06882-3","volume":"41","author":"G Ceschia","year":"2026","unstructured":"Ceschia G, Longo G, Igeno J, Vidal E (2026) Technicalities, current evidence, and clinical indications of hemoadsorption in critically ill children. Pediatr Nephrol 41:649\u2013662. https:\/\/doi.org\/10.1007\/s00467-025-06882-3","journal-title":"Pediatr Nephrol"},{"key":"7406_CR58","doi-asserted-by":"publisher","first-page":"409","DOI":"10.3390\/antibiotics15040409","volume":"15","author":"S Kenda","year":"2026","unstructured":"Kenda S, Guben\u0161ek J, Vovk T (2026) Antibiotics and other drugs removal by the CytoSorb\u00ae haemoadsorber: a systematic review of available evidence. Antibiotics (Basel) 15:409. https:\/\/doi.org\/10.3390\/antibiotics15040409","journal-title":"Antibiotics (Basel)"},{"key":"7406_CR59","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1111\/sdi.12251","volume":"27","author":"V Lavergne","year":"2014","unstructured":"Lavergne V, Ouellet G, Bouchard J, Galvao T, Kielstein JT, Roberts DM, Kanji S, Mowry JB, Calello DP, Hoffman RS, Gosselin S, Nolin TD, Goldfarb DS, Burdmann EA, Dargan PI, Decker BS, Hoegberg LC, Maclaren R, Megarbane B, Sowinski KM, Yates C, Mactier R, Wiegand T, Ghannoum M (2014) Guidelines for reporting case studies on extracorporeal treatments in poisonings: methodology. Semin Dial 27:407\u2013414. https:\/\/doi.org\/10.1111\/sdi.12251","journal-title":"Semin Dial"}],"container-title":["Pediatric Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-026-07406-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00467-026-07406-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00467-026-07406-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T07:05:07Z","timestamp":1781852707000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00467-026-07406-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,19]]},"references-count":59,"alternative-id":["7406"],"URL":"https:\/\/doi.org\/10.1007\/s00467-026-07406-3","relation":{},"ISSN":["0931-041X","1432-198X"],"issn-type":[{"value":"0931-041X","type":"print"},{"value":"1432-198X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,19]]},"assertion":[{"value":"19 February 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 May 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 May 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 June 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Given the retrospective and anonymized nature of this single case report, formal ethics committee approval was waived by the local Ethics Committee. All data are published anonymously, and the identity of the patient described cannot be retrieved from the data provided in this paper. Written informed consent for publication of the case details was obtained from the patient\u2019s parents\/legal guardians. All personal data were handled confidentially and anonymously, in accordance with the Declaration of Helsinki and local data protection regulations.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}