{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T10:57:21Z","timestamp":1781607441305,"version":"3.54.5"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T00:00:00Z","timestamp":1723420800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T00:00:00Z","timestamp":1723420800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Schmerz"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Hintergrund<\/jats:title>\n                    <jats:p>Die Behandlung des Nervenwurzelreizsyndroms beim lumbalen Bandscheibenvorfall kann chirurgisch oder konservativ erfolgen. Die konservativen Behandlungskonzepte zeigten einen Erfolg bei 90\u202f% der Patienten, in der Mehrzahl der Studien wurde jedoch kein strukturiertes Behandlungskonzept angewendet.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ziel der Arbeit<\/jats:title>\n                    <jats:p>In der Studie untersuchten wir den Effekt einer kombinierten konservativen Therapie des Wurzelreizsyndroms mit mechanischer Physiotherapie (McKenzie), Gabapentin sowie transforaminalen epiduralen Kortikosteroidinjektionen bei 40\u00a0Patienten w\u00e4hrend eines 10-t\u00e4gigen station\u00e4ren Aufenthalts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methoden<\/jats:title>\n                    <jats:p>Neben der klinischen Untersuchung einschlie\u00dflich des Straight-leg-raise-Tests und Finger-Boden-Abstands wurde die Schmerzst\u00e4rke in Ruhe und nach einer Gehstrecke von 5\u202fm erhoben und eine Elektromyographie der Kennmuskeln durchgef\u00fchrt. Die Oswestry Pain Disability Scale sowie Schmerzschwereskala nach von Korff wurden erhoben und neuropathische Schmerzkomponenten mit der painDETECT-Skala erfasst. Ferner wurden die Dauer der Arbeitsunf\u00e4higkeit sowie die Notwendigkeit einer Operation innerhalb des Beobachtungszeitraums erfasst. Die Untersuchungen wurden am Tag der Aufnahme, an den Tagen\u00a03,\u00a06 und\u00a010 sowie 3\u00a0Monate nach Entlassung durchgef\u00fchrt.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ergebnisse<\/jats:title>\n                    <jats:p>W\u00e4hrend der Behandlung konnte eine kontinuierliche Schmerzreduktion in Ruhe sowie beim Gehen von 5\u202fm, Verbesserung des Straight-leg-raise-Tests sowie Verminderung des Finger-Boden-Abstands dokumentiert werden. Da die 3\u00a0Verfahren mit zeitlichem Abstand eingesetzt wurden, konnte gezeigt werden, dass alle signifikant zur Besserung beitrugen. Alle 3\u00a0Verfahren wurden ohne wesentliche Nebenwirkungen vertragen und die anhaltende Besserung bei der Nachuntersuchung nach 12\u00a0Wochen best\u00e4tigte die Nachhaltigkeit des Konzepts. Bei Aufnahme zeigten 32\u202f% der Patienten eine \u00fcberwiegend neuropathische Schmerzkomponente, welche nach 3\u00a0Monaten auf 7\u202f% reduziert war. In der Elektromyographie fanden sich bei Aufnahme bei 70\u202f% der Patienten Auff\u00e4lligkeiten. Eine Kraftminderung zeigte sich bei Aufnahme bei 28\u00a0Patienten, bei der Kontrolle nur noch bei 7\u00a0Patienten. Auch die Lebensqualit\u00e4t war signifikant verbessert und die Patienten konnten 5,8\u00a0Wochen nach Behandlungsbeginn die Berufst\u00e4tigkeit wieder aufnehmen. 3\u00a0von 40\u00a0Patienten ben\u00f6tigten wegen anhaltender Schmerzen eine Operation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Konsequenz<\/jats:title>\n                    <jats:p>Das untersuchte kombinierte Behandlungsprogramm ist effektiv und wird gut toleriert.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00482-024-00824-y","type":"journal-article","created":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T14:02:37Z","timestamp":1723471357000},"page":"220-228","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Konservative Kombinationstherapie beim lumbalen Bandscheibenvorfall mit Nervenwurzelreizsyndrom mit mechanischer Physiotherapie (McKenzie), Gabapentin und transforaminalen epiduralen Infiltrationen","Conservative combination therapy of sciatica due to lumbar disc herniation with mechanical physiotherapy (McKenzie), gabapentin, and transforaminal epidural injections"],"prefix":"10.1007","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0071-5914","authenticated-orcid":false,"given":"Manuela","family":"J\u00e4ntsch-Rieckert","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Rommel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Verena","family":"K\u00e4stner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lotte","family":"Maercklin-Rommel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg","family":"J\u00e4ger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,8,12]]},"reference":[{"key":"824_CR1","doi-asserted-by":"publisher","first-page":"1777","DOI":"10.1097\/00007632-199608010-00011","volume":"21","author":"SJ Atlas","year":"1996","unstructured":"Atlas\u00a0SJ, Deyo\u00a0RA, Keller\u00a0RB et\u00a0al (1996) The Maine Lumbar Spine Study, Part II. 1\u2011year outcomes of surgical and nonsurgical management of sciatica. Spine 21:1777\u20131786","journal-title":"Spine"},{"key":"824_CR2","doi-asserted-by":"publisher","first-page":"1179","DOI":"10.1097\/00007632-200105150-00017","volume":"26","author":"SJ Atlas","year":"2001","unstructured":"Atlas\u00a0SJ, Keller\u00a0RB, Chang\u00a0Y et\u00a0al (2001) Surgical and nonsurgical management of sciatica secondary to a\u00a0lumbar disc herniation: five-year outcomes from the Maine Lumbar Spine Study. Spine 26:1179\u20131187","journal-title":"Spine"},{"key":"824_CR3","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1016\/j.pain.2010.04.013","volume":"150","author":"R Baron","year":"2010","unstructured":"Baron\u00a0R, Freynhagen\u00a0R, T\u00f6lle\u00a0TR et\u00a0al (2010) The efficacy and safety of pregabalin in the treatment of neuropathic pain associated with chronic lumbosacral radiculopathy. Pain 150:420\u2013427","journal-title":"Pain"},{"key":"824_CR4","doi-asserted-by":"publisher","first-page":"155","DOI":"10.3233\/NRE-2010-0547","volume":"26","author":"D Br\u00f6tz","year":"2010","unstructured":"Br\u00f6tz\u00a0D, Burkard\u00a0S, Weller\u00a0M (2010) A prospective study of mechanical physiotherapy for lumbar disk prolapse: five year follow-up and final report. NeuroRehabilitation 26:155\u2013158","journal-title":"NeuroRehabilitation"},{"key":"824_CR5","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1007\/s00415-003-1077-1","volume":"250","author":"D Br\u00f6tz","year":"2003","unstructured":"Br\u00f6tz\u00a0D, K\u00fcker\u00a0W, Maschke\u00a0E et\u00a0al (2003) A prospective trial of mechanical physiotherapy for lumbar disk prolapse. J\u00a0Neurol 250:746\u2013749","journal-title":"J Neurol"},{"issue":"4","key":"824_CR6","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/S0004-9514(14)60110-0","volume":"50","author":"HA Clare","year":"2004","unstructured":"Clare\u00a0HA, Adams\u00a0R, Maher\u00a0CG (2004) A systematic review of efficacy of McKenzie therapy for spinal pain. Aust J Physiother 50(4):209\u2013216","journal-title":"Aust J Physiother"},{"key":"824_CR7","doi-asserted-by":"publisher","first-page":"1426","DOI":"10.1097\/00007632-200207010-00010","volume":"27","author":"G Dubourg","year":"2002","unstructured":"Dubourg\u00a0G, Rozenberg\u00a0S, Fautrel\u00a0B et\u00a0al (2002) A pilot study on the recovery from paresis after lumbar disc herniation. Spine 27:1426\u20131431","journal-title":"Spine"},{"key":"824_CR8","doi-asserted-by":"publisher","first-page":"2940","DOI":"10.1097\/00007632-200011150-00017","volume":"25","author":"JC Fairbank","year":"2000","unstructured":"Fairbank\u00a0JC, Pynsent\u00a0PB (2000) The Oswestry Disability Index. Spine 25:2940\u20132952","journal-title":"Spine"},{"key":"824_CR9","doi-asserted-by":"publisher","first-page":"1911","DOI":"10.1185\/030079906X132488","volume":"22","author":"R Freynhagen","year":"2006","unstructured":"Freynhagen\u00a0R, Baron\u00a0R, Gockel\u00a0U, T\u00f6lle\u00a0TR (2006) PainDETECT: a\u00a0new screening questionnaire to identify neuropathic components in patients with back pain. Curr Med Res Opin 22:1911\u20131920","journal-title":"Curr Med Res Opin"},{"key":"824_CR10","doi-asserted-by":"publisher","first-page":"1294","DOI":"10.1093\/pm\/pny252","volume":"20","author":"R Gastaldi","year":"2019","unstructured":"Gastaldi\u00a0R, Durand\u00a0M, Roustit\u00a0M et\u00a0al (2019) Short-term Efficiency and Tolerance of Ketoprofen and Methylprednisolone in Acute Sciatica: A\u00a0Randomized Trial. Pain Med 20:1294\u20131299","journal-title":"Pain Med"},{"key":"#cr-split#-824_CR11.1","unstructured":"Greitemann B, Schmidt R (2020) Leitlinie zur konservativen, operativen und rehabil. Versorgung bei Bandscheibenvorf\u00e4llen mit radikul\u00e4rer Symptomatik"},{"key":"#cr-split#-824_CR11.2","unstructured":"S2k Leitlinie. https:\/\/www.awmf.org\/leitlinien\/detail\/ll\/033-048.html. Zugegriffen: 27. Dez. 2020"},{"issue":"5","key":"824_CR12","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1177\/2192568218800050","volume":"9","author":"RM Kanna","year":"2019","unstructured":"Kanna\u00a0RM, Shetty\u00a0AP, Rajasekaran\u00a0S (2019) Predictors of successful outcomes of selective nerve root blocks for acute lumbar disc herniation. Global Spine\u00a0J 9(5):473\u2013479","journal-title":"Global Spine J"},{"key":"824_CR13","doi-asserted-by":"publisher","first-page":"1070","DOI":"10.2176\/nmc.50.1070","volume":"50","author":"O Kasimcan","year":"2010","unstructured":"Kasimcan\u00a0O, Kaptan\u00a0H (2010) Efficacy of gabapentin for radiculopathy caused by lumbar spinal stenosis and lumbar disk hernia. Neurol Med Chir 50:1070\u20131073","journal-title":"Neurol Med Chir"},{"key":"824_CR14","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.spinee.2017.08.264","volume":"18","author":"DJ Kennedy","year":"2018","unstructured":"Kennedy\u00a0DJ, Zheng\u00a0PZ, Smuck\u00a0M et\u00a0al (2018) A minimum of 5\u2011year follow-up after lumbar transforaminal epidural steroid injections in patients with lumbar radicular pain due to intervertebral disc herniation. Spine\u00a0J 18:29\u201335","journal-title":"Spine J"},{"key":"824_CR15","doi-asserted-by":"crossref","unstructured":"Lequin MB, Verbaan D, Jacobs WC et\u00a0al (2013) Surgery versus prolonged conservative treatment for sciatica: 5\u2011year results of a\u00a0randomised controlled trial. BMJ Open 3(5)","DOI":"10.1136\/bmjopen-2012-002534"},{"key":"824_CR16","doi-asserted-by":"publisher","first-page":"557","DOI":"10.2106\/00004623-195032030-00009","volume":"32-A","author":"K Lindblom","year":"1950","unstructured":"Lindblom\u00a0K, Hultqvist\u00a0G (1950) Absorption of protruded disc tissue. J\u00a0Bone Joint Surg Am 32-A:557\u2013560","journal-title":"J Bone Joint Surg Am"},{"key":"824_CR17","doi-asserted-by":"publisher","first-page":"e070730","DOI":"10.1136\/bmj-2022-07073","volume":"381","author":"C Liu","year":"2023","unstructured":"Liu\u00a0C, Ferreira\u00a0GE, Abdel Shaheed\u00a0C et\u00a0al (2023) Surgical versus non-surgical treatment for sciatica: systematic review and meta-analysis of randomised controlled trials. BMJ 381:e70730. https:\/\/doi.org\/10.1136\/bmj-2022-07073","journal-title":"BMJ"},{"key":"824_CR18","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1055\/s-0042-105603","volume":"11","author":"H Mayer","year":"2016","unstructured":"Mayer\u00a0H, Heider\u00a0F (2016) Der lumbale Bandscheibenvorfall. Orthop\u00e4die Unfallchirurgie Up2date 11:427\u2013447","journal-title":"Orthop\u00e4die Unfallchirurgie Up2date"},{"key":"824_CR19","volume-title":"The Lumbar Spine: Mechanical Diagnosis and Therapy","author":"RA McKenzie","year":"1981","unstructured":"McKenzie\u00a0RA (1981) The Lumbar Spine: Mechanical Diagnosis and Therapy. Spinal Publications"},{"issue":"4","key":"824_CR20","first-page":"492","volume":"19","author":"FI Namnagani","year":"2019","unstructured":"Namnagani\u00a0FI, Mashabi\u00a0AS, Yaseen\u00a0KM et\u00a0al (2019) The effectiveness of McKenzie method compared to manual therapy for treating chronic low back pain: a\u00a0systematic review. J\u00a0Musculoskelet Neuronal Interact 19(4):492\u2013499","journal-title":"J Musculoskelet Neuronal Interact"},{"key":"824_CR21","doi-asserted-by":"publisher","first-page":"1817","DOI":"10.1016\/j.spinee.2013.07.456","volume":"14","author":"GM Overdevest","year":"2014","unstructured":"Overdevest\u00a0GM, Vleggeert-Lankamp\u00a0CL, Jacobs\u00a0WC et\u00a0al (2014) Recovery of motor deficit accompanying sciatica\u2014subgroup analysis of a\u00a0randomized controlled trial. Spine\u00a0J 14:1817\u20131824","journal-title":"Spine J"},{"key":"824_CR22","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1097\/WNF.0000000000000145","volume":"39","author":"S Ozturk","year":"2016","unstructured":"Ozturk\u00a0S, Ucler\u00a0N, Hergunsel\u00a0OB et\u00a0al (2016) The Efficacy of Gabapentin in the Treatment of Pain Due to Far Lateral Lumbar Disc Herniations. Clin Neuropharmacol 39:140\u2013143","journal-title":"Clin Neuropharmacol"},{"key":"824_CR23","doi-asserted-by":"publisher","first-page":"1702","DOI":"10.1097\/00007632-200208150-00004","volume":"27","author":"T Petersen","year":"2002","unstructured":"Petersen\u00a0T, Kryger\u00a0P, Ekdahl\u00a0C et\u00a0al (2002) The effect of McKenzie therapy as compared with that of intensive strengthening training for the treatment of patients with subacute or chronic low back pain: A\u00a0randomized controlled trial. Spine 27:1702\u20131709","journal-title":"Spine"},{"key":"824_CR24","doi-asserted-by":"publisher","first-page":"1355","DOI":"10.1136\/bmj.a143","volume":"336","author":"WC Peul","year":"2008","unstructured":"Peul\u00a0WC, Hout\u00a0WBVD, Brand\u00a0R et\u00a0al (2008) Prolonged conservative care versus early surgery in patients with sciatica caused by lumbar disc herniation: two year results of a\u00a0randomised controlled trial. BMJ 336:1355\u20131358","journal-title":"BMJ"},{"key":"824_CR25","doi-asserted-by":"publisher","first-page":"2245","DOI":"10.1056\/NEJMoa064039","volume":"356","author":"WC Peul","year":"2007","unstructured":"Peul\u00a0WC, van Houwelingen\u00a0HC, van den Hout\u00a0WB et\u00a0al (2007) Surgery versus prolonged conservative treatment for sciatica. N\u00a0Engl J Med 356:2245\u20132256","journal-title":"N Engl J Med"},{"key":"824_CR26","doi-asserted-by":"publisher","first-page":"e497","DOI":"10.1136\/bmj.e497","volume":"344","author":"RZ Pinto","year":"2012","unstructured":"Pinto\u00a0RZ, Maher\u00a0CG, Ferreira\u00a0ML et\u00a0al (2012) Drugs for relief of pain in patients with sciatica: systematic review and meta-analysis. BMJ 344:e497","journal-title":"BMJ"},{"key":"824_CR27","first-page":"Cd012382","volume":"10","author":"E Rasmussen-Barr","year":"2016","unstructured":"Rasmussen-Barr\u00a0E, Held\u00a0U, Grooten\u00a0WJ et\u00a0al (2016) Non-steroidal anti-inflammatory drugs for sciatica. Cochrane Database Syst Rev 10:Cd12382","journal-title":"Cochrane Database Syst Rev"},{"key":"824_CR28","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1097\/00007632-198904000-00018","volume":"14","author":"JA Saal","year":"1989","unstructured":"Saal\u00a0JA, Saal\u00a0JS (1989) Nonoperative treatment of herniated lumbar intervertebral disc with radiculopathy. An outcome study. Spine 14:431\u2013437","journal-title":"Spine"},{"key":"824_CR29","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1093\/pm\/pnz160","volume":"21","author":"CC Smith","year":"2020","unstructured":"Smith\u00a0CC, McCormick\u00a0ZL, Mattie\u00a0R et\u00a0al (2020) The Effectiveness of Lumbar Transforaminal Injection of Steroid for the Treatment of Radicular Pain: A\u00a0Comprehensive Review of the Published Data. Pain Med 21:472\u2013487","journal-title":"Pain Med"},{"key":"824_CR30","unstructured":"Volbracht E, F\u00fcrchtenicht A, Grote-Westrick M (2017) R\u00fcckenoperationen. In: Bertelsmann Stiftung (Hrsg.) SPOTLIGHT Gesundheit Nr.\u00a07\/2017. https:\/\/www.bertelsmann-stiftung.de\/de\/publikationen\/publikation\/did\/spotlight-gesundheit-rueckenoperationen. Zugegriffen: 27. M\u00e4rz 2024"},{"key":"824_CR31","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/0304-3959(92)90154-4","volume":"50","author":"M Von Korff","year":"1992","unstructured":"Von Korff\u00a0M, Ormel\u00a0J, Keefe\u00a0FJ, Dworkin\u00a0SF (1992) Grading the severity of chronic pain. Pain 50:133\u2013149","journal-title":"Pain"},{"key":"824_CR32","doi-asserted-by":"publisher","first-page":"2451","DOI":"10.1001\/jama.296.20.2451","volume":"296","author":"JN Weinstein","year":"2006","unstructured":"Weinstein\u00a0JN, Lurie\u00a0JD, Tosteson\u00a0TD et\u00a0al (2006) Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research Trial (SPORT) observational cohort. JAMA 296:2451\u20132459","journal-title":"JAMA"},{"issue":"3","key":"824_CR33","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1163\/156856903767650718","volume":"15","author":"K Yildirim","year":"2013","unstructured":"Yildirim\u00a0K, Sisecioglu\u00a0M, Karatay\u00a0S et\u00a0al (2013) The effectiveness of Gabapentin in patients with chronic radiculopathy. Pain Clin 15(3):213\u2013218. https:\/\/doi.org\/10.1163\/156856903767650718","journal-title":"Pain Clin"}],"container-title":["Der Schmerz"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00482-024-00824-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00482-024-00824-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00482-024-00824-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T10:35:19Z","timestamp":1781606119000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00482-024-00824-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,12]]},"references-count":34,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["824"],"URL":"https:\/\/doi.org\/10.1007\/s00482-024-00824-y","relation":{},"ISSN":["0932-433X","1432-2129"],"issn-type":[{"value":"0932-433X","type":"print"},{"value":"1432-2129","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,12]]},"assertion":[{"value":"30 May 2024","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 August 2024","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"M.\u00a0J\u00e4ntsch-Rieckert, O.\u00a0Rommel, V.\u00a0K\u00e4stner, L.\u00a0Maercklin-Rommel und G.\u00a0J\u00e4ger geben an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"Alle beschriebenen Untersuchungen am Menschen oder an menschlichem Gewebe wurden mit Zustimmung der zust\u00e4ndigen Ethikkommission, im Einklang mit nationalem Recht sowie gem\u00e4\u00df der Deklaration von Helsinki von 1975 (in der aktuellen, \u00fcberarbeiteten Fassung) durchgef\u00fchrt. Das Studienprotokoll wurde von der Ethikkommission der Landes\u00e4rztekammer Baden-W\u00fcrttemberg (AZ-2016-075) genehmigt. Von allen beteiligten Patient\/-innen liegt eine Einverst\u00e4ndniserkl\u00e4rung vor.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}